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Items: 1 to 50 of 1061

1.

NosP signaling modulates the NO/H-NOX-mediated multicomponent c-di-GMP network and biofilm formation in Shewanella oneidensis.

Nisbett LM, Binnenkade L, Bacon BA, Hossain S, Kotloski NJ, Brutinel ED, Hartmann R, Drescher K, Arora DP, Muralidharan S, Thormann K, Gralnick JA, Boon EM.

Biochemistry. 2019 Nov 4. doi: 10.1021/acs.biochem.9b00706. [Epub ahead of print]

PMID:
31682418
2.

Breakdown of Vibrio cholerae biofilm architecture induced by antibiotics disrupts community barrier function.

Díaz-Pascual F, Hartmann R, Lempp M, Vidakovic L, Song B, Jeckel H, Thormann KM, Yildiz FH, Dunkel J, Link H, Nadell CD, Drescher K.

Nat Microbiol. 2019 Oct 28. doi: 10.1038/s41564-019-0579-2. [Epub ahead of print]

PMID:
31659297
3.

Quantitative particle uptake by cells as analyzed by different methods.

Parak WJ, Ashraf S, Hassan Said A, Hartmann R, Assmann MA, Feliu N, Lenz P.

Angew Chem Int Ed Engl. 2019 Oct 27. doi: 10.1002/anie.201906303. [Epub ahead of print]

PMID:
31657113
4.

Length dependent activation of OAS proteins by dsRNA.

Wang Y, Holleufer A, Gad HH, Hartmann R.

Cytokine. 2019 Oct 17;126:154867. doi: 10.1016/j.cyto.2019.154867. [Epub ahead of print]

PMID:
31629990
5.

An Assessment of Handover Culture and Preferred Information in the Transitions of Care of Elderly Patients.

Trivedi S, Dick A, Beckett S, Hartmann RJ, Roberts C, Lyster K, Stempien J.

Cureus. 2019 Jul 29;11(7):e5267. doi: 10.7759/cureus.5267.

6.

Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors.

Sommer R, Rox K, Wagner S, Hauck D, Henrikus SS, Newsad S, Arnold T, Ryckmans T, Brönstrup M, Imberty A, Varrot A, Hartmann RW, Titz A.

J Med Chem. 2019 Oct 24;62(20):9201-9216. doi: 10.1021/acs.jmedchem.9b01120. Epub 2019 Oct 11.

PMID:
31553873
7.

Fungal biofilm morphology impacts hypoxia fitness and disease progression.

Kowalski CH, Kerkaert JD, Liu KW, Bond MC, Hartmann R, Nadell CD, Stajich JE, Cramer RA.

Nat Microbiol. 2019 Sep 23. doi: 10.1038/s41564-019-0558-7. [Epub ahead of print]

PMID:
31548684
8.

Correction to: Optimizing conditions for labeling of mesenchymal stromal cells (MSCs) with gold nanoparticles: a prerequisite for in vivo tracking of MSCs.

Nold P, Hartmann R, Feliu N, Kantner K, Gamal M, Pelaz B, Hühn J, Sun X, Jungebluth P, Del Pino P, Hackstein H, Macchiarini P, Parak WJ, Brendel C.

J Nanobiotechnology. 2019 Sep 17;17(1):98. doi: 10.1186/s12951-019-0527-6.

9.

Type I and type III interferons differ in their adjuvant activities for influenza vaccines.

Ye L, Ohnemus A, Ong LC, Gad HH, Hartmann R, Lycke N, Staeheli P.

J Virol. 2019 Sep 11. pii: JVI.01262-19. doi: 10.1128/JVI.01262-19. [Epub ahead of print]

PMID:
31511392
10.

Energy-dispersive Laue diffraction by means of a pnCCD detector coupled to a CsI(Tl) scintillator using ultra-hard X-ray synchrotron radiation.

Shokr M, Tosson A, Abboud A, Algashi A, Schlosser D, Hartmann R, Klaus M, Genzel C, Strüder L, Pietsch U.

J Synchrotron Radiat. 2019 Sep 1;26(Pt 5):1612-1620. doi: 10.1107/S160057751900626X. Epub 2019 Jul 25.

PMID:
31490151
11.

What makes the hepatitis C virus evolve?

O'Brien TR, Hartmann R, Prokunina-Olsson L.

Elife. 2019 Sep 3;8. pii: e50148. doi: 10.7554/eLife.50148.

12.

Development of Biarylalkyl Carboxylic Acid Amides with Improved Anti-schistosomal Activity.

Peter Ventura AM, Haeberlein S, Lange-Grünweller K, Grünweller A, Hartmann RK, Grevelding CG, Schlitzer M.

ChemMedChem. 2019 Nov 6;14(21):1856-1862. doi: 10.1002/cmdc.201900423. Epub 2019 Sep 18.

PMID:
31454168
13.

Polyketides and a Dihydroquinolone Alkaloid from a Marine-Derived Strain of the Fungus Metarhizium marquandii.

El-Kashef DH, Daletos G, Plenker M, Hartmann R, Mándi A, Kurtán T, Weber H, Lin W, Ancheeva E, Proksch P.

J Nat Prod. 2019 Sep 27;82(9):2460-2469. doi: 10.1021/acs.jnatprod.9b00125. Epub 2019 Aug 21.

PMID:
31432669
14.

Brominated Azaphilones from the Sponge-Associated Fungus Penicillium canescens Strain 4.14.6a.

Frank M, Hartmann R, Plenker M, Mándi A, Kurtán T, Özkaya FC, Müller WEG, Kassack MU, Hamacher A, Lin W, Liu Z, Proksch P.

J Nat Prod. 2019 Aug 23;82(8):2159-2166. doi: 10.1021/acs.jnatprod.9b00151. Epub 2019 Jul 30.

PMID:
31359750
15.

Design, Synthesis, and Biological Characterization of Orally Active 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors Targeting the Prevention of Osteoporosis.

Abdelsamie AS, Salah M, Siebenbürger L, Merabet A, Scheuer C, Frotscher M, Müller ST, Zierau O, Vollmer G, Menger MD, Laschke MW, van Koppen CJ, Marchais-Oberwinkler S, Hartmann RW.

J Med Chem. 2019 Aug 8;62(15):7289-7301. doi: 10.1021/acs.jmedchem.9b00932. Epub 2019 Jul 25.

PMID:
31343176
16.

Homologs of aquifex aeolicus protein-only RNase P are not the major RNase P activities in the archaea haloferax volcanii and methanosarcina mazei.

Schwarz TS, Wäber NB, Feyh R, Weidenbach K, Schmitz RA, Marchfelder A, Hartmann RK.

IUBMB Life. 2019 Aug;71(8):1109-1116. doi: 10.1002/iub.2122. Epub 2019 Jul 8.

PMID:
31283101
17.

Identification of an IRF3 variant and defective antiviral interferon responses in a patient with severe influenza.

Thomsen MM, Jørgensen SE, Storgaard M, Kristensen LS, Gjedsted J, Christiansen M, Gad HH, Hartmann R, Mogensen TH.

Eur J Immunol. 2019 Jun 28. doi: 10.1002/eji.201848083. [Epub ahead of print] No abstract available.

PMID:
31250433
18.

Exact open quantum system dynamics: Optimal frequency vs time representation of bath correlations.

Hartmann R, Werther M, Grossmann F, Strunz WT.

J Chem Phys. 2019 Jun 21;150(23):234105. doi: 10.1063/1.5097158.

PMID:
31228905
19.

Effects of 17β-HSD2 inhibition in bones on osteoporosis based on an animal rat model.

Müller ST, Pählig S, Merabet A, Abdelsamie AS, van Koppen CJ, Marchais-Oberwinkler S, Hartmann RW, Zierau O, Vollmer G.

J Steroid Biochem Mol Biol. 2019 Sep;192:105405. doi: 10.1016/j.jsbmb.2019.105405. Epub 2019 Jun 8.

PMID:
31185280
20.

Development of potential preclinical candidates with promising in vitro ADME profile for the inhibition of type 1 and type 2 17β-Hydroxysteroid dehydrogenases: Design, synthesis, and biological evaluation.

Abdelsamie AS, Salah M, Siebenbürger L, Hamed MM, Börger C, van Koppen CJ, Frotscher M, Hartmann RW.

Eur J Med Chem. 2019 Sep 15;178:93-107. doi: 10.1016/j.ejmech.2019.05.084. Epub 2019 May 31.

PMID:
31176098
21.

Defective interferon priming and impaired antiviral responses in a patient with an IRF7 variant and severe influenza.

Thomsen MM, Jørgensen SE, Gad HH, Storgaard M, Gjedsted J, Christiansen M, Hartmann R, Mogensen TH.

Med Microbiol Immunol. 2019 Dec;208(6):869-876. doi: 10.1007/s00430-019-00623-8. Epub 2019 Jun 6.

PMID:
31172279
22.

Melatonin effects on pulmonary tissue in the experimental model of Hepatopulmonary Syndrome.

Bosco AD, Schedler FB, Colares JR, Schemitt EG, Hartmann RM, Forgiarini Junior LA, Dias AS, Marroni NP.

J Bras Pneumol. 2019 May 30;45(3):e20170164. doi: 10.1590/1806-3713/e20170164. English, Portuguese.

23.

Emergence of three-dimensional order and structure in growing biofilms.

Hartmann R, Singh PK, Pearce P, Mok R, Song B, Díaz-Pascual F, Dunkel J, Drescher K.

Nat Phys. 2019 Apr 26;15(3):251-256. doi: 10.1038/s41567-018-0356-9. Epub 2018 Nov 26.

24.

The Influence of the rs30461 Single Nucleotide Polymorphism on IFN-λ1 Activity and Secretion.

Møhlenberg M, Gad HH, Hartmann R.

J Interferon Cytokine Res. 2019 Oct;39(10):661-667. doi: 10.1089/jir.2019.0051. Epub 2019 May 22.

PMID:
31120365
25.

Autologous Matrix-Induced Chondrogenesis for Osteochondral Lesions of the Talus: A Clinical and Radiological 2- to 8-Year Follow-up Study.

Weigelt L, Hartmann R, Pfirrmann C, Espinosa N, Wirth SH.

Am J Sports Med. 2019 Jun;47(7):1679-1686. doi: 10.1177/0363546519841574. Epub 2019 May 14.

PMID:
31084491
26.

Enantioselective total synthesis of altersolanol A and N.

Mechsner B, Böse D, Hogenkamp F, Ledermann N, Hartmann R, Bochinsky K, Frey W, Pietruszka J.

Bioorg Med Chem. 2019 Jul 1;27(13):2991-2997. doi: 10.1016/j.bmc.2019.04.033. Epub 2019 Apr 27.

PMID:
31072649
27.

Plant species affects establishment of Escherichia coli O157:H7 gfp+ on leafy vegetables.

Darlison J, Mieli M, Bengtsson T, Hartmann R, Mogren L, Vågsholm I, Karlsson M, Alsanius BW.

J Appl Microbiol. 2019 Jul;127(1):292-305. doi: 10.1111/jam.14299. Epub 2019 Jun 3.

PMID:
31054164
28.

Protective action of glutamine in rats with severe acute liver failure.

Schemitt EG, Hartmann RM, Colares JR, Licks F, Salvi JO, Marroni CA, Marroni NP.

World J Hepatol. 2019 Mar 27;11(3):273-286. doi: 10.4254/wjh.v11.i3.273.

29.

Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase.

Akram M, Patt M, Kaserer T, Temml V, Waratchareeyakul W, Kratschmar DV, Haupenthal J, Hartmann RW, Odermatt A, Schuster D.

J Steroid Biochem Mol Biol. 2019 Sep;192:105358. doi: 10.1016/j.jsbmb.2019.04.007. Epub 2019 Apr 6.

PMID:
30965118
30.

Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers.

Elfgen A, Hupert M, Bochinsky K, Tusche M, González de San Román Martin E, Gering I, Sacchi S, Pollegioni L, Huesgen PF, Hartmann R, Santiago-Schübel B, Kutzsche J, Willbold D.

Sci Rep. 2019 Apr 5;9(1):5715. doi: 10.1038/s41598-019-41993-6.

31.
32.

Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin.

Ye L, Schnepf D, Becker J, Ebert K, Tanriver Y, Bernasconi V, Gad HH, Hartmann R, Lycke N, Staeheli P.

Nat Immunol. 2019 May;20(5):593-601. doi: 10.1038/s41590-019-0345-x. Epub 2019 Mar 18.

PMID:
30886417
33.

Insects in anthelminthics research: Lady beetle-derived harmonine affects survival, reproduction and stem cell proliferation of Schistosoma mansoni.

Kellershohn J, Thomas L, Hahnel SR, Grünweller A, Hartmann RK, Hardt M, Vilcinskas A, Grevelding CG, Haeberlein S.

PLoS Negl Trop Dis. 2019 Mar 14;13(3):e0007240. doi: 10.1371/journal.pntd.0007240. eCollection 2019 Mar.

34.

Application of triple quadrupole mass spectrometry for the characterization of antibody-drug conjugates.

Källsten M, Pijnappel M, Hartmann R, Lehmann F, Kovac L, Lind SB, Bergquist J.

Anal Bioanal Chem. 2019 May;411(12):2569-2576. doi: 10.1007/s00216-019-01699-0. Epub 2019 Mar 8.

35.

Insights into the complex role of GRAS transcription factors in the arbuscular mycorrhiza symbiosis.

Hartmann RM, Schaepe S, Nübel D, Petersen AC, Bertolini M, Vasilev J, Küster H, Hohnjec N.

Sci Rep. 2019 Mar 4;9(1):3360. doi: 10.1038/s41598-019-40214-4.

36.

Site-Specific Cleavage of RNAs Derived from the PIM1 3'-UTR by a Metal-Free Artificial Ribonuclease.

Zellmann F, Thomas L, Scheffer U, Hartmann RK, Göbel MW.

Molecules. 2019 Feb 23;24(4). pii: E807. doi: 10.3390/molecules24040807.

37.

Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing.

Gobbi S, Hu Q, Foschi G, Catanzaro E, Belluti F, Rampa A, Fimognari C, Hartmann RW, Bisi A.

Bioorg Chem. 2019 May;86:401-409. doi: 10.1016/j.bioorg.2019.01.066. Epub 2019 Jan 30.

PMID:
30769265
38.

Heart Rate Variability as Indicator of Clinical State in Depression.

Hartmann R, Schmidt FM, Sander C, Hegerl U.

Front Psychiatry. 2019 Jan 17;9:735. doi: 10.3389/fpsyt.2018.00735. eCollection 2018.

39.

2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site.

Bestgen B, Krimm I, Kufareva I, Kamal AAM, Seetoh WG, Abell C, Hartmann RW, Abagyan R, Cochet C, Le Borgne M, Engel M, Lomberget T.

J Med Chem. 2019 Feb 28;62(4):1803-1816. doi: 10.1021/acs.jmedchem.8b01766. Epub 2019 Feb 18.

PMID:
30689953
40.

2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action.

Bestgen B, Kufareva I, Seetoh W, Abell C, Hartmann RW, Abagyan R, Le Borgne M, Filhol O, Cochet C, Lomberget T, Engel M.

J Med Chem. 2019 Feb 28;62(4):1817-1836. doi: 10.1021/acs.jmedchem.8b01765. Epub 2019 Feb 13.

PMID:
30689946
41.

Hit evaluation of an α-helical peptide: Ala-scan, truncation and sidechain-to-sidechain macrocyclization of an RNA polymerase Inhibitor.

Kamal AAM, Habib M, Haupenthal J, Hartmann RW, Empting M.

Biol Chem. 2019 Feb 25;400(3):333-342. doi: 10.1515/hsz-2018-0333.

PMID:
30657738
42.

Targeted Endocrine Therapy: Design, Synthesis, and Proof-of-Principle of 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors in Bone Fracture Healing.

Abdelsamie AS, Herath S, Biskupek Y, Börger C, Siebenbürger L, Salah M, Scheuer C, Marchais-Oberwinkler S, Frotscher M, Pohlemann T, Menger MD, Hartmann RW, Laschke MW, van Koppen CJ.

J Med Chem. 2019 Feb 14;62(3):1362-1372. doi: 10.1021/acs.jmedchem.8b01493. Epub 2019 Jan 15.

PMID:
30645111
43.

Correction to: Influence of foraminal enlargement on the healing of periapical lesions in rat molars.

Brandão PM, de Figueiredo JAP, Morgental RD, Scarparo RK, Hartmann RC, Waltrick SBG, Souza RA.

Clin Oral Investig. 2019 Apr;23(4):2001-2003. doi: 10.1007/s00784-018-2780-8.

PMID:
30635786
44.

Learning the space-time phase diagram of bacterial swarm expansion.

Jeckel H, Jelli E, Hartmann R, Singh PK, Mok R, Totz JF, Vidakovic L, Eckhardt B, Dunkel J, Drescher K.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1489-1494. doi: 10.1073/pnas.1811722116. Epub 2019 Jan 11.

45.

2'-Fluoro-Pyrimidine-Modified RNA Aptamers Specific for Lipopolysaccharide Binding Protein (LBP).

Aldag J, Persson T, Hartmann RK.

Int J Mol Sci. 2018 Dec 5;19(12). pii: E3883. doi: 10.3390/ijms19123883.

46.

Anti-inflammatory and antioxidant effect of melatonin on recovery from muscular trauma induced in rats.

Ostjen CA, Rosa CGS, Hartmann RM, Schemitt EG, Colares JR, Marroni NP.

Exp Mol Pathol. 2019 Feb;106:52-59. doi: 10.1016/j.yexmp.2018.12.001. Epub 2018 Dec 4.

PMID:
30521792
47.

Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents.

Castoldi A, Empting M, De Rossi C, Mayr K, Dersch P, Hartmann R, Müller R, Gordon S, Lehr CM.

Pharm Res. 2018 Dec 5;36(1):22. doi: 10.1007/s11095-018-2521-3.

48.

Highly Potent 17β-HSD2 Inhibitors with a Promising Pharmacokinetic Profile for Targeted Osteoporosis Therapy.

Siebenbuerger L, Hernandez-Olmos V, Abdelsamie AS, Frotscher M, van Koppen CJ, Marchais-Oberwinkler S, Scheuer C, Laschke MW, Menger MD, Boerger C, Hartmann RW.

J Med Chem. 2018 Dec 13;61(23):10724-10738. doi: 10.1021/acs.jmedchem.8b01373. Epub 2018 Nov 27.

PMID:
30480443
49.

Influence of foraminal enlargement on the healing of periapical lesions in rat molars.

Brandão PM, de Figueiredo JAP, Morgental RD, Scarparo RK, Hartmann RC, Waltrick SBG, Souza RA.

Clin Oral Investig. 2019 Apr;23(4):1985-1991. doi: 10.1007/s00784-018-2628-2. Epub 2018 Nov 1. Erratum in: Clin Oral Investig. 2019 Jan 11;:.

PMID:
30386994
50.

Dendritic cells and their relation to apical peridontitis.

Figueiredo JAP, Machado AM, Oliveira VP, Hartmann R, Waltrick SBG, Borba MG, Brew MC, Estrela CRA, Böttcher DE.

Braz Oral Res. 2018 Oct 18;32(suppl 1):e71. doi: 10.1590/1807-3107BOR-2018.vol32.0071. Review.

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