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Electronic Decay of Singly Charged Ground-State Ions by Charge Transfer via van der Waals Bonds.

Hans A, Miteva T, Holzapfel X, Ozga C, Schmidt P, Otto H, Hartmann G, Richter C, Sisourat N, Ehresmann A, Gokhberg K, Hergenhahn U, Knie A.

Phys Rev Lett. 2019 Nov 22;123(21):213001. doi: 10.1103/PhysRevLett.123.213001.


High RIG-I expression in ovarian cancer associates with an immune-escape signature and poor clinical outcome.

Wolf D, Fiegl H, Zeimet AG, Wieser V, Marth C, Sprung S, Sopper S, Hartmann G, Reimer D, Boesch M.

Int J Cancer. 2019 Dec 4. doi: 10.1002/ijc.32818. [Epub ahead of print]


Attosecond transient absorption spooktroscopy: a ghost imaging approach to ultrafast absorption spectroscopy.

Driver T, Li S, Champenois EG, Duris J, Ratner D, Lane TJ, Rosenberger P, Al-Haddad A, Averbukh V, Barnard T, Berrah N, Bostedt C, Bucksbaum PH, Coffee R, DiMauro LF, Fang L, Garratt D, Gatton A, Guo Z, Hartmann G, Haxton D, Helml W, Huang Z, LaForge A, Kamalov A, Kling MF, Knurr J, Lin MF, Lutman AA, MacArthur JP, Marangos JP, Nantel M, Natan A, Obaid R, O'Neal JT, Shivaram NH, Schori A, Walter P, Li Wang A, Wolf TJA, Marinelli A, Cryan JP.

Phys Chem Chem Phys. 2019 Dec 3. doi: 10.1039/c9cp03951a. [Epub ahead of print]


Interferon-beta-induced changes in neuroimaging phenotypes of appetitive motivation and reactivity to emotional salience.

Coch C, Viviani R, Breitfeld J, Münzer K, Dassler-Plencker J, Holdenrieder S, Coenen M, Steffens M, Müller M, Hartmann G, Stingl J.

Neuroimage Clin. 2019;24:102020. doi: 10.1016/j.nicl.2019.102020. Epub 2019 Nov 14.


The PNPLA3 I148M variant promotes lipid-induced hepatocyte secretion of CXC chemokines establishing a tumorigenic milieu.

Nischalke HD, Lutz P, Bartok E, Krämer B, Langhans B, Frizler R, Berg T, Hampe J, Buch S, Datz C, Stickel F, Hartmann G, Strassburg CP, Nattermann J, Spengler U.

J Mol Med (Berl). 2019 Nov;97(11):1589-1600. doi: 10.1007/s00109-019-01836-3. Epub 2019 Oct 21.


[Detector Based Determination of Water Absorbed Dose According to DIN 6800 Teil 1: Suggestion for an Extension of the Fundamental Formalism].

Hartmann GH, Hensley F, Kapsch RP, Poppe B, Sauer O, Würfel J, Zink K.

Z Med Phys. 2019 Oct 1. pii: S0939-3889(19)30033-9. doi: 10.1016/j.zemedi.2019.05.001. [Epub ahead of print] German.


Setup for multicoincidence experiments of photons in the extreme ultraviolet to visible spectral range and charged particles-The solid angle maximization approach.

Hans A, Ozga C, Schmidt P, Hartmann G, Nehls A, Wenzel P, Richter C, Lant C, Holzapfel X, Viehmann JH, Hergenhahn U, Ehresmann A, Knie A.

Rev Sci Instrum. 2019 Sep;90(9):093104. doi: 10.1063/1.5109104.


Recovery of High-Energy Photoelectron Circular Dichroism through Fano Interference.

Hartmann G, Ilchen M, Schmidt P, Küstner-Wetekam C, Ozga C, Scholz F, Buck J, Trinter F, Viefhaus J, Ehresmann A, Schöffler MS, Knie A, Demekhin PV.

Phys Rev Lett. 2019 Jul 26;123(4):043202. doi: 10.1103/PhysRevLett.123.043202.


A Monte Carlo study on the PTW 60019 microDiamond detector.

Hartmann GH, Zink K.

Med Phys. 2019 Nov;46(11):5159-5172. doi: 10.1002/mp.13721. Epub 2019 Sep 24.


Commissioning of a photoelectron spectrometer for soft X-ray photon diagnostics at the European XFEL.

Laksman J, Buck J, Glaser L, Planas M, Dietrich F, Liu J, Maltezopoulos T, Scholz F, Seltmann J, Hartmann G, Ilchen M, Freund W, Kujala N, Viefhaus J, Grünert J.

J Synchrotron Radiat. 2019 Jul 1;26(Pt 4):1010-1016. doi: 10.1107/S1600577519003552. Epub 2019 May 15.


Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.

Regula JT, Lundh von Leithner P, Foxton R, Barathi VA, Chui Ming GC, Tun SBB, Wey YS, Iwata D, Dostalek M, Moelleken J, Stubenrauch KG, Nogoceke E, Widmer G, Strassburger P, Koss MJ, Klein C, Shima DT, Hartmann G.

EMBO Mol Med. 2019 May;11(5). pii: e10666. doi: 10.15252/emmm.201910666. No abstract available.


Human TLR8 Senses RNA From Plasmodium falciparum-Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells.

Coch C, Hommertgen B, Zillinger T, Daßler-Plenker J, Putschli B, Nastaly M, Kümmerer BM, Scheunemann JF, Schumak B, Specht S, Schlee M, Barchet W, Hoerauf A, Bartok E, Hartmann G.

Front Immunol. 2019 Mar 27;10:371. doi: 10.3389/fimmu.2019.00371. eCollection 2019.


Targeted Nanoparticle Delivery of Bifunctional RIG-I Agonists to Pancreatic Cancer.

Zillinger T, Hartmann G.

Mol Ther. 2019 Mar 6;27(3):491-492. doi: 10.1016/j.ymthe.2019.02.005. Epub 2019 Feb 20. No abstract available.


Efficient Fluorescence Quenching by Distant Production of a Free Electron.

Hans A, Schmidt P, Ozga C, Richter C, Otto H, Holzapfel X, Hartmann G, Ehresmann A, Hergenhahn U, Knie A.

J Phys Chem Lett. 2019 Mar 7;10(5):1078-1082. doi: 10.1021/acs.jpclett.9b00124. Epub 2019 Feb 21.


Size limits of magnetic-domain engineering in continuous in-plane exchange-bias prototype films.

Gaul A, Emmrich D, Ueltzhöffer T, Huckfeldt H, Doğanay H, Hackl J, Khan MI, Gottlob DM, Hartmann G, Beyer A, Holzinger D, Nemšák S, Schneider CM, Gölzhäuser A, Reiss G, Ehresmann A.

Beilstein J Nanotechnol. 2018 Dec 3;9:2968-2979. doi: 10.3762/bjnano.9.276. eCollection 2018.


Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes.

Johns DG, LeVoci L, Krsmanovic M, Lu M, Hartmann G, Xu S, Wang SP, Chen Y, Bateman T, Blaustein RO.

Drug Metab Dispos. 2019 Mar;47(3):227-233. doi: 10.1124/dmd.118.084525. Epub 2018 Dec 19.


Speleothem record of geomagnetic South Atlantic Anomaly recurrence.

Trindade RIF, Jaqueto P, Terra-Nova F, Brandt D, Hartmann GA, Feinberg JM, Strauss BE, Novello VF, Cruz FW, Karmann I, Cheng H, Edwards RL.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13198-13203. doi: 10.1073/pnas.1809197115. Epub 2018 Dec 10.


Theoretical evaluation of thermal decomposition of dichlorosilane for plasma-enhanced atomic layer deposition of silicon nitride: the important role of surface hydrogen.

Hartmann G, Ventzek PLG, Iwao T, Ishibashi K, Hwang GS.

Phys Chem Chem Phys. 2018 Nov 28;20(46):29152-29158. doi: 10.1039/c8cp06272b.


Symmetry breakdown of electron emission in extreme ultraviolet photoionization of argon.

Ilchen M, Hartmann G, Gryzlova EV, Achner A, Allaria E, Beckmann A, Braune M, Buck J, Callegari C, Coffee RN, Cucini R, Danailov M, De Fanis A, Demidovich A, Ferrari E, Finetti P, Glaser L, Knie A, Lindahl AO, Plekan O, Mahne N, Mazza T, Raimondi L, Roussel E, Scholz F, Seltmann J, Shevchuk I, Svetina C, Walter P, Zangrando M, Viefhaus J, Grum-Grzhimailo AN, Meyer M.

Nat Commun. 2018 Nov 7;9(1):4659. doi: 10.1038/s41467-018-07152-7.


Fluence calculation methods in Monte Carlo dosimetry simulations.

Hartmann GH, Andreo P.

Z Med Phys. 2019 Aug;29(3):239-248. doi: 10.1016/j.zemedi.2018.08.003. Epub 2018 Sep 24.


ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.

Aden K, Tran F, Ito G, Sheibani-Tezerji R, Lipinski S, Kuiper JW, Tschurtschenthaler M, Saveljeva S, Bhattacharyya J, Häsler R, Bartsch K, Luzius A, Jentzsch M, Falk-Paulsen M, Stengel ST, Welz L, Schwarzer R, Rabe B, Barchet W, Krautwald S, Hartmann G, Pasparakis M, Blumberg RS, Schreiber S, Kaser A, Rosenstiel P.

J Exp Med. 2018 Nov 5;215(11):2868-2886. doi: 10.1084/jem.20171029. Epub 2018 Sep 25.


Application of Physiologically Based Pharmacokinetic Modeling to Predict Pharmacokinetics in Healthy Japanese Subjects.

Matsumoto Y, Cabalu T, Sandhu P, Hartmann G, Iwasa T, Yoshitsugu H, Gibson C, Uemura N.

Clin Pharmacol Ther. 2019 Apr;105(4):1018-1030. doi: 10.1002/cpt.1240. Epub 2018 Dec 4.


Direct RIG-I activation in human NK cells induces TRAIL-dependent cytotoxicity toward autologous melanoma cells.

Daßler-Plenker J, Paschen A, Putschli B, Rattay S, Schmitz S, Goldeck M, Bartok E, Hartmann G, Coch C.

Int J Cancer. 2019 Apr 1;144(7):1645-1656. doi: 10.1002/ijc.31874. Epub 2019 Jan 9.


Can a power law improve prediction of pain recovery trajectory?

Hartmann GC, George SZ.

Pain Rep. 2018 Jun 13;3(4):e657. doi: 10.1097/PR9.0000000000000657. eCollection 2018 Jul-Aug. Review.


PBPK Modeling Strategy for Predicting Complex Drug Interactions of Letermovir as a Perpetrator in Support of Product Labeling.

Wang YH, Chen D, Hartmann G, Cho CR, Menzel K.

Clin Pharmacol Ther. 2019 Feb;105(2):515-523. doi: 10.1002/cpt.1120. Epub 2018 Sep 11.


Improved sensitivity for detection of breast cancer by combination of miR-34a and tumor markers CA 15-3 or CEA.

Zaleski M, Kobilay M, Schroeder L, Debald M, Semaan A, Hettwer K, Uhlig S, Kuhn W, Hartmann G, Holdenrieder S.

Oncotarget. 2018 Apr 27;9(32):22523-22536. doi: 10.18632/oncotarget.25077. eCollection 2018 Apr 27.


Extreme Ultraviolet to Visible Dispersed Single Photon Detection for Highly Sensitive Sensing of Fundamental Processes in Diverse Samples.

Hans A, Schmidt P, Ozga C, Hartmann G, Holzapfel X, Ehresmann A, Knie A.

Materials (Basel). 2018 May 23;11(6). pii: E869. doi: 10.3390/ma11060869. Erratum in: Materials (Basel). 2018 Dec 25;12(1):.


Note: Soft X-ray transmission polarizer based on ferromagnetic thin films.

Müller L, Hartmann G, Schleitzer S, Berntsen MH, Walther M, Rysov R, Roseker W, Scholz F, Seltmann J, Glaser L, Viefhaus J, Mertens K, Bagschik K, Frömter R, De Fanis A, Shevchuk I, Medjanik K, Öhrwall G, Oepen HP, Martins M, Meyer M, Grübel G.

Rev Sci Instrum. 2018 Mar;89(3):036103. doi: 10.1063/1.5018396.


Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients.

Plenker D, Bertrand M, de Langen AJ, Riedel R, Lorenz C, Scheel AH, Müller J, Brägelmann J, Daßler-Plenker J, Kobe C, Persigehl T, Kluge A, Wurdinger T, Schellen P, Hartmann G, Zacherle T, Menon R, Thunnissen E, Büttner R, Griesinger F, Wolf J, Heukamp L, Sos ML, Heuckmann JM.

Clin Cancer Res. 2018 Mar 15;24(6):1337-1343. doi: 10.1158/1078-0432.CCR-17-3001. Epub 2017 Dec 28.


Type I interferon-mediated autoinflammation due to DNase II deficiency.

Rodero MP, Tesser A, Bartok E, Rice GI, Della Mina E, Depp M, Beitz B, Bondet V, Cagnard N, Duffy D, Dussiot M, Frémond ML, Gattorno M, Guillem F, Kitabayashi N, Porcheray F, Rieux-Laucat F, Seabra L, Uggenti C, Volpi S, Zeef LAH, Alyanakian MA, Beltrand J, Bianco AM, Boddaert N, Brouzes C, Candon S, Caorsi R, Charbit M, Fabre M, Faletra F, Girard M, Harroche A, Hartmann E, Lasne D, Marcuzzi A, Neven B, Nitschke P, Pascreau T, Pastore S, Picard C, Picco P, Piscianz E, Polak M, Quartier P, Rabant M, Stocco G, Taddio A, Uettwiller F, Valencic E, Vozzi D, Hartmann G, Barchet W, Hermine O, Bader-Meunier B, Tommasini A, Crow YJ.

Nat Commun. 2017 Dec 19;8(1):2176. doi: 10.1038/s41467-017-01932-3.


Transsynaptic Mapping of Second-Order Taste Neurons in Flies by trans-Tango.

Talay M, Richman EB, Snell NJ, Hartmann GG, Fisher JD, Sorkaç A, Santoyo JF, Chou-Freed C, Nair N, Johnson M, Szymanski JR, Barnea G.

Neuron. 2017 Nov 15;96(4):783-795.e4. doi: 10.1016/j.neuron.2017.10.011. Epub 2017 Oct 26.


Clinical performance of LOCI™-based tumor marker assays for tumor markers CA 15-3, CA 125, CEA, CA 19-9 and AFP in gynecological cancers.

Dolscheid-Pommerich RC, Keyver-Paik M, Hecking T, Kuhn W, Hartmann G, Stoffel-Wagner B, Holdenrieder S.

Tumour Biol. 2017 Oct;39(10):1010428317730246. doi: 10.1177/1010428317730246.


Analysis of integrated clinical trial protocols in early phases of medicinal product development.

Fruhner K, Hartmann G, Sudhop T.

Eur J Clin Pharmacol. 2017 Dec;73(12):1565-1577. doi: 10.1007/s00228-017-2335-y. Epub 2017 Sep 18.


Controlling Plasmon-Enhanced Fluorescence via Intersystem Crossing in Photoswitchable Molecules.

Wang M, Hartmann G, Wu Z, Scarabelli L, Rajeeva BB, Jarrett JW, Perillo EP, Dunn AK, Liz-Marzán LM, Hwang GS, Zheng Y.

Small. 2017 Oct;13(38). doi: 10.1002/smll.201701763. Epub 2017 Aug 21.


RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection.

Coch C, Stümpel JP, Lilien-Waldau V, Wohlleber D, Kümmerer BM, Bekeredjian-Ding I, Kochs G, Garbi N, Herberhold S, Schuberth-Wagner C, Ludwig J, Barchet W, Schlee M, Hoerauf A, Bootz F, Staeheli P, Hartmann G, Hartmann E.

Mol Ther. 2017 Sep 6;25(9):2093-2103. doi: 10.1016/j.ymthe.2017.07.003. Epub 2017 Jul 8.


Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.

Layer JP, Kronmüller MT, Quast T, van den Boorn-Konijnenberg D, Effern M, Hinze D, Althoff K, Schramm A, Westermann F, Peifer M, Hartmann G, Tüting T, Kolanus W, Fischer M, Schulte J, Hölzel M.

Oncoimmunology. 2017 Apr 28;6(6):e1320626. doi: 10.1080/2162402X.2017.1320626. eCollection 2017.


Diagnostic relevance of a novel multiplex immunoassay panel in breast cancer.

Hermann N, Dressen K, Schroeder L, Debald M, Schildberg FA, Walgenbach-Bruenagel G, Hettwer K, Uhlig S, Kuhn W, Hartmann G, Holdenrieder S.

Tumour Biol. 2017 Jun;39(6):1010428317711381. doi: 10.1177/1010428317711381.


Cathepsin S inhibition combines control of systemic and peripheral pathomechanisms of autoimmune tissue injury.

Tato M, Kumar SV, Liu Y, Mulay SR, Moll S, Popper B, Eberhard JN, Thomasova D, Rufer AC, Gruner S, Haap W, Hartmann G, Anders HJ.

Sci Rep. 2017 Jun 5;7(1):2775. doi: 10.1038/s41598-017-01894-y.


Accurate prediction of X-ray pulse properties from a free-electron laser using machine learning.

Sanchez-Gonzalez A, Micaelli P, Olivier C, Barillot TR, Ilchen M, Lutman AA, Marinelli A, Maxwell T, Achner A, Agåker M, Berrah N, Bostedt C, Bozek JD, Buck J, Bucksbaum PH, Montero SC, Cooper B, Cryan JP, Dong M, Feifel R, Frasinski LJ, Fukuzawa H, Galler A, Hartmann G, Hartmann N, Helml W, Johnson AS, Knie A, Lindahl AO, Liu J, Motomura K, Mucke M, O'Grady C, Rubensson JE, Simpson ER, Squibb RJ, Såthe C, Ueda K, Vacher M, Walke DJ, Zhaunerchyk V, Coffee RN, Marangos JP.

Nat Commun. 2017 Jun 5;8:15461. doi: 10.1038/ncomms15461.


Generating circularly polarized radiation in the extreme ultraviolet spectral range at the free-electron laser FLASH.

von Korff Schmising C, Weder D, Noll T, Pfau B, Hennecke M, Strüber C, Radu I, Schneider M, Staeck S, Günther CM, Lüning J, Merhe AED, Buck J, Hartmann G, Viefhaus J, Treusch R, Eisebitt S.

Rev Sci Instrum. 2017 May;88(5):053903. doi: 10.1063/1.4983056.


Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.

Regula JT, Lundh von Leithner P, Foxton R, Barathi VA, Gemmy Cheung CM, Bo Tun SB, Wey YS, Iwata D, Dostalek M, Moelleken J, Stubenrauch KG, Nogoceke E, Widmer G, Strassburger P, Koss MJ, Klein C, Shima DT, Hartmann G.

EMBO Mol Med. 2017 Jul;9(7):985. doi: 10.15252/emmm.201707895. No abstract available.


Free-Circulating Methylated DNA in Blood for Diagnosis, Staging, Prognosis, and Monitoring of Head and Neck Squamous Cell Carcinoma Patients: An Observational Prospective Cohort Study.

Schröck A, Leisse A, de Vos L, Gevensleben H, Dröge F, Franzen A, Wachendörfer M, Schröck F, Ellinger J, Teschke M, Wilhelm-Buchstab T, Landsberg J, Holdenrieder S, Hartmann G, Field JK, Bootz F, Kristiansen G, Dietrich D.

Clin Chem. 2017 Jul;63(7):1288-1296. doi: 10.1373/clinchem.2016.270207. Epub 2017 May 17.


Diagnostic Performance of a Novel Multiplex Immunoassay in Colorectal Cancer.

Dressen K, Hermann N, Manekeller S, Walgenbach-Bruenagel G, Schildberg FA, Hettwer K, Uhlig S, Kalff JC, Hartmann G, Holdenrieder S.

Anticancer Res. 2017 May;37(5):2477-2486.


RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation.

Engel C, Brügmann G, Lambing S, Mühlenbeck LH, Marx S, Hagen C, Horváth D, Goldeck M, Ludwig J, Herzner AM, Drijfhout JW, Wenzel D, Coch C, Tüting T, Schlee M, Hornung V, Hartmann G, Van den Boorn JG.

Cancer Immunol Res. 2017 Jun;5(6):455-467. doi: 10.1158/2326-6066.CIR-16-0129-T. Epub 2017 May 3.


Nucleic Acid Immunity.

Hartmann G.

Adv Immunol. 2017;133:121-169. doi: 10.1016/ Epub 2016 Dec 15.


Dedicated high dose rate 192Ir brachytherapy radiation fields for in vitro cell exposures at variable source-target cell distances: killing of mammalian cells depends on temporal dose rate fluctuation.

Veigel C, Hartmann GH, Fritz P, Debus J, Weber KJ.

Phys Med Biol. 2017 Feb 1;62(4):1613-1631. doi: 10.1088/1361-6560/aa587c. [Epub ahead of print]


Clinical Performance of CEA, CA19-9, CA15-3, CA125 and AFP in Gastrointestinal Cancer Using LOCI™-based Assays.

Dolscheid-Pommerich RC, Manekeller S, Walgenbach-Brünagel G, Kalff JC, Hartmann G, Wagner BS, Holdenrieder S.

Anticancer Res. 2017 Jan;37(1):353-359.


G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes.

Herzner AM, Wolter S, Zillinger T, Schmitz S, Barchet W, Hartmann G, Bartok E, Schlee M.

Sci Rep. 2016 Dec 12;6:38405. doi: 10.1038/srep38405.

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