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Items: 1 to 50 of 668

1.

Theoretical evaluation of thermal decomposition of dichlorosilane for plasma-enhanced atomic layer deposition of silicon nitride: the important role of surface hydrogen.

Hartmann G, Ventzek PLG, Iwao T, Ishibashi K, Hwang GS.

Phys Chem Chem Phys. 2018 Nov 14. doi: 10.1039/c8cp06272b. [Epub ahead of print]

PMID:
30426994
2.

Symmetry breakdown of electron emission in extreme ultraviolet photoionization of argon.

Ilchen M, Hartmann G, Gryzlova EV, Achner A, Allaria E, Beckmann A, Braune M, Buck J, Callegari C, Coffee RN, Cucini R, Danailov M, De Fanis A, Demidovich A, Ferrari E, Finetti P, Glaser L, Knie A, Lindahl AO, Plekan O, Mahne N, Mazza T, Raimondi L, Roussel E, Scholz F, Seltmann J, Shevchuk I, Svetina C, Walter P, Zangrando M, Viefhaus J, Grum-Grzhimailo AN, Meyer M.

Nat Commun. 2018 Nov 7;9(1):4659. doi: 10.1038/s41467-018-07152-7.

3.

Fluence calculation methods in Monte Carlo dosimetry simulations.

Hartmann GH, Andreo P.

Z Med Phys. 2018 Sep 24. pii: S0939-3889(18)30065-5. doi: 10.1016/j.zemedi.2018.08.003. [Epub ahead of print]

PMID:
30262137
4.

ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.

Aden K, Tran F, Ito G, Sheibani-Tezerji R, Lipinski S, Kuiper JW, Tschurtschenthaler M, Saveljeva S, Bhattacharyya J, Häsler R, Bartsch K, Luzius A, Jentzsch M, Falk-Paulsen M, Stengel ST, Welz L, Schwarzer R, Rabe B, Barchet W, Krautwald S, Hartmann G, Pasparakis M, Blumberg RS, Schreiber S, Kaser A, Rosenstiel P.

J Exp Med. 2018 Nov 5;215(11):2868-2886. doi: 10.1084/jem.20171029. Epub 2018 Sep 25.

5.

Application of Physiologically-Based Pharmacokinetic Modeling to Predict Pharmacokinetics in Healthy Japanese Subjects.

Matsumoto Y, Cabalu T, Sandhu P, Hartmann G, Iwasa T, Yoshitsugu H, Gibson C, Uemura N.

Clin Pharmacol Ther. 2018 Sep 25. doi: 10.1002/cpt.1240. [Epub ahead of print]

PMID:
30252941
6.

Direct RIG-I activation in human NK cells induces TRAIL-dependent cytotoxicity towards autologous melanoma cells.

Daßler-Plenker J, Paschen A, Putschli B, Rattay S, Schmitz S, Goldeck M, Bartok E, Hartmann G, Coch C.

Int J Cancer. 2018 Sep 19. doi: 10.1002/ijc.31874. [Epub ahead of print]

PMID:
30230526
7.

Can a power law improve prediction of pain recovery trajectory?

Hartmann GC, George SZ.

Pain Rep. 2018 Jun 13;3(4):e657. doi: 10.1097/PR9.0000000000000657. eCollection 2018 Jul-Aug. Review.

8.
9.

PBPK Modeling Strategy for Predicting Complex Drug Interactions of Letermovir as a Perpetrator in Support of Product Labeling.

Wang YH, Chen D, Hartmann G, Cho CR, Menzel K.

Clin Pharmacol Ther. 2018 Jun 14. doi: 10.1002/cpt.1120. [Epub ahead of print]

PMID:
29901213
10.

Improved sensitivity for detection of breast cancer by combination of miR-34a and tumor markers CA 15-3 or CEA.

Zaleski M, Kobilay M, Schroeder L, Debald M, Semaan A, Hettwer K, Uhlig S, Kuhn W, Hartmann G, Holdenrieder S.

Oncotarget. 2018 Apr 27;9(32):22523-22536. doi: 10.18632/oncotarget.25077. eCollection 2018 Apr 27.

11.

Extreme Ultraviolet to Visible Dispersed Single Photon Detection for Highly Sensitive Sensing of Fundamental Processes in Diverse Samples.

Hans A, Schmidt P, Ozga C, Hartmann G, Holzapfel X, Ehresmann A, Knie A.

Materials (Basel). 2018 May 23;11(6). pii: E869. doi: 10.3390/ma11060869.

12.

Note: Soft X-ray transmission polarizer based on ferromagnetic thin films.

Müller L, Hartmann G, Schleitzer S, Berntsen MH, Walther M, Rysov R, Roseker W, Scholz F, Seltmann J, Glaser L, Viefhaus J, Mertens K, Bagschik K, Frömter R, De Fanis A, Shevchuk I, Medjanik K, Öhrwall G, Oepen HP, Martins M, Meyer M, Grübel G.

Rev Sci Instrum. 2018 Mar;89(3):036103. doi: 10.1063/1.5018396.

PMID:
29604789
13.

Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients.

Plenker D, Bertrand M, de Langen AJ, Riedel R, Lorenz C, Scheel AH, Müller J, Brägelmann J, Daßler-Plenker J, Kobe C, Persigehl T, Kluge A, Wurdinger T, Schellen P, Hartmann G, Zacherle T, Menon R, Thunnissen E, Büttner R, Griesinger F, Wolf J, Heukamp L, Sos ML, Heuckmann JM.

Clin Cancer Res. 2018 Mar 15;24(6):1337-1343. doi: 10.1158/1078-0432.CCR-17-3001. Epub 2017 Dec 28.

PMID:
29284707
14.

Type I interferon-mediated autoinflammation due to DNase II deficiency.

Rodero MP, Tesser A, Bartok E, Rice GI, Della Mina E, Depp M, Beitz B, Bondet V, Cagnard N, Duffy D, Dussiot M, Frémond ML, Gattorno M, Guillem F, Kitabayashi N, Porcheray F, Rieux-Laucat F, Seabra L, Uggenti C, Volpi S, Zeef LAH, Alyanakian MA, Beltrand J, Bianco AM, Boddaert N, Brouzes C, Candon S, Caorsi R, Charbit M, Fabre M, Faletra F, Girard M, Harroche A, Hartmann E, Lasne D, Marcuzzi A, Neven B, Nitschke P, Pascreau T, Pastore S, Picard C, Picco P, Piscianz E, Polak M, Quartier P, Rabant M, Stocco G, Taddio A, Uettwiller F, Valencic E, Vozzi D, Hartmann G, Barchet W, Hermine O, Bader-Meunier B, Tommasini A, Crow YJ.

Nat Commun. 2017 Dec 19;8(1):2176. doi: 10.1038/s41467-017-01932-3.

15.

Transsynaptic Mapping of Second-Order Taste Neurons in Flies by trans-Tango.

Talay M, Richman EB, Snell NJ, Hartmann GG, Fisher JD, Sorkaç A, Santoyo JF, Chou-Freed C, Nair N, Johnson M, Szymanski JR, Barnea G.

Neuron. 2017 Nov 15;96(4):783-795.e4. doi: 10.1016/j.neuron.2017.10.011. Epub 2017 Oct 26.

16.

Clinical performance of LOCI™-based tumor marker assays for tumor markers CA 15-3, CA 125, CEA, CA 19-9 and AFP in gynecological cancers.

Dolscheid-Pommerich RC, Keyver-Paik M, Hecking T, Kuhn W, Hartmann G, Stoffel-Wagner B, Holdenrieder S.

Tumour Biol. 2017 Oct;39(10):1010428317730246. doi: 10.1177/1010428317730246.

PMID:
29034816
17.

Analysis of integrated clinical trial protocols in early phases of medicinal product development.

Fruhner K, Hartmann G, Sudhop T.

Eur J Clin Pharmacol. 2017 Dec;73(12):1565-1577. doi: 10.1007/s00228-017-2335-y. Epub 2017 Sep 18.

18.

Controlling Plasmon-Enhanced Fluorescence via Intersystem Crossing in Photoswitchable Molecules.

Wang M, Hartmann G, Wu Z, Scarabelli L, Rajeeva BB, Jarrett JW, Perillo EP, Dunn AK, Liz-Marzán LM, Hwang GS, Zheng Y.

Small. 2017 Oct;13(38). doi: 10.1002/smll.201701763. Epub 2017 Aug 21.

19.

RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection.

Coch C, Stümpel JP, Lilien-Waldau V, Wohlleber D, Kümmerer BM, Bekeredjian-Ding I, Kochs G, Garbi N, Herberhold S, Schuberth-Wagner C, Ludwig J, Barchet W, Schlee M, Hoerauf A, Bootz F, Staeheli P, Hartmann G, Hartmann E.

Mol Ther. 2017 Sep 6;25(9):2093-2103. doi: 10.1016/j.ymthe.2017.07.003. Epub 2017 Jul 8.

20.

Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.

Layer JP, Kronmüller MT, Quast T, van den Boorn-Konijnenberg D, Effern M, Hinze D, Althoff K, Schramm A, Westermann F, Peifer M, Hartmann G, Tüting T, Kolanus W, Fischer M, Schulte J, Hölzel M.

Oncoimmunology. 2017 Apr 28;6(6):e1320626. doi: 10.1080/2162402X.2017.1320626. eCollection 2017.

21.

Diagnostic relevance of a novel multiplex immunoassay panel in breast cancer.

Hermann N, Dressen K, Schroeder L, Debald M, Schildberg FA, Walgenbach-Bruenagel G, Hettwer K, Uhlig S, Kuhn W, Hartmann G, Holdenrieder S.

Tumour Biol. 2017 Jun;39(6):1010428317711381. doi: 10.1177/1010428317711381.

PMID:
28618926
22.

Cathepsin S inhibition combines control of systemic and peripheral pathomechanisms of autoimmune tissue injury.

Tato M, Kumar SV, Liu Y, Mulay SR, Moll S, Popper B, Eberhard JN, Thomasova D, Rufer AC, Gruner S, Haap W, Hartmann G, Anders HJ.

Sci Rep. 2017 Jun 5;7(1):2775. doi: 10.1038/s41598-017-01894-y.

23.

Accurate prediction of X-ray pulse properties from a free-electron laser using machine learning.

Sanchez-Gonzalez A, Micaelli P, Olivier C, Barillot TR, Ilchen M, Lutman AA, Marinelli A, Maxwell T, Achner A, Agåker M, Berrah N, Bostedt C, Bozek JD, Buck J, Bucksbaum PH, Montero SC, Cooper B, Cryan JP, Dong M, Feifel R, Frasinski LJ, Fukuzawa H, Galler A, Hartmann G, Hartmann N, Helml W, Johnson AS, Knie A, Lindahl AO, Liu J, Motomura K, Mucke M, O'Grady C, Rubensson JE, Simpson ER, Squibb RJ, Såthe C, Ueda K, Vacher M, Walke DJ, Zhaunerchyk V, Coffee RN, Marangos JP.

Nat Commun. 2017 Jun 5;8:15461. doi: 10.1038/ncomms15461.

24.

Generating circularly polarized radiation in the extreme ultraviolet spectral range at the free-electron laser FLASH.

von Korff Schmising C, Weder D, Noll T, Pfau B, Hennecke M, Strüber C, Radu I, Schneider M, Staeck S, Günther CM, Lüning J, Merhe AED, Buck J, Hartmann G, Viefhaus J, Treusch R, Eisebitt S.

Rev Sci Instrum. 2017 May;88(5):053903. doi: 10.1063/1.4983056.

PMID:
28571434
25.

Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.

Regula JT, Lundh von Leithner P, Foxton R, Barathi VA, Gemmy Cheung CM, Bo Tun SB, Wey YS, Iwata D, Dostalek M, Moelleken J, Stubenrauch KG, Nogoceke E, Widmer G, Strassburger P, Koss MJ, Klein C, Shima DT, Hartmann G.

EMBO Mol Med. 2017 Jul;9(7):985. doi: 10.15252/emmm.201707895. No abstract available.

26.

Free-Circulating Methylated DNA in Blood for Diagnosis, Staging, Prognosis, and Monitoring of Head and Neck Squamous Cell Carcinoma Patients: An Observational Prospective Cohort Study.

Schröck A, Leisse A, de Vos L, Gevensleben H, Dröge F, Franzen A, Wachendörfer M, Schröck F, Ellinger J, Teschke M, Wilhelm-Buchstab T, Landsberg J, Holdenrieder S, Hartmann G, Field JK, Bootz F, Kristiansen G, Dietrich D.

Clin Chem. 2017 Jul;63(7):1288-1296. doi: 10.1373/clinchem.2016.270207. Epub 2017 May 17.

27.

Diagnostic Performance of a Novel Multiplex Immunoassay in Colorectal Cancer.

Dressen K, Hermann N, Manekeller S, Walgenbach-Bruenagel G, Schildberg FA, Hettwer K, Uhlig S, Kalff JC, Hartmann G, Holdenrieder S.

Anticancer Res. 2017 May;37(5):2477-2486.

PMID:
28476816
28.

RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation.

Engel C, Brügmann G, Lambing S, Mühlenbeck LH, Marx S, Hagen C, Horváth D, Goldeck M, Ludwig J, Herzner AM, Drijfhout JW, Wenzel D, Coch C, Tüting T, Schlee M, Hornung V, Hartmann G, Van den Boorn JG.

Cancer Immunol Res. 2017 Jun;5(6):455-467. doi: 10.1158/2326-6066.CIR-16-0129-T. Epub 2017 May 3.

29.

Nucleic Acid Immunity.

Hartmann G.

Adv Immunol. 2017;133:121-169. doi: 10.1016/bs.ai.2016.11.001. Epub 2016 Dec 15.

PMID:
28215278
30.

Dedicated high dose rate 192Ir brachytherapy radiation fields for in vitro cell exposures at variable source-target cell distances: killing of mammalian cells depends on temporal dose rate fluctuation.

Veigel C, Hartmann GH, Fritz P, Debus J, Weber KJ.

Phys Med Biol. 2017 Feb 1;62(4):1613-1631. doi: 10.1088/1361-6560/aa587c. [Epub ahead of print]

PMID:
28145285
31.

Clinical Performance of CEA, CA19-9, CA15-3, CA125 and AFP in Gastrointestinal Cancer Using LOCI™-based Assays.

Dolscheid-Pommerich RC, Manekeller S, Walgenbach-Brünagel G, Kalff JC, Hartmann G, Wagner BS, Holdenrieder S.

Anticancer Res. 2017 Jan;37(1):353-359.

PMID:
28011514
32.

G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes.

Herzner AM, Wolter S, Zillinger T, Schmitz S, Barchet W, Hartmann G, Bartok E, Schlee M.

Sci Rep. 2016 Dec 12;6:38405. doi: 10.1038/srep38405.

33.

RIG-I activation induces the release of extracellular vesicles with antitumor activity.

Daßler-Plenker J, Reiners KS, van den Boorn JG, Hansen HP, Putschli B, Barnert S, Schuberth-Wagner C, Schubert R, Tüting T, Hallek M, Schlee M, Hartmann G, Pogge von Strandmann E, Coch C.

Oncoimmunology. 2016 Aug 19;5(10):e1219827. eCollection 2016.

34.

Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.

Regula JT, Lundh von Leithner P, Foxton R, Barathi VA, Cheung CM, Bo Tun SB, Wey YS, Iwata D, Dostalek M, Moelleken J, Stubenrauch KG, Nogoceke E, Widmer G, Strassburger P, Koss MJ, Klein C, Shima DT, Hartmann G.

EMBO Mol Med. 2016 Nov 2;8(11):1265-1288. doi: 10.15252/emmm.201505889. Print 2016 Nov.

35.

LYSOPHOSPHATIDIC ACIDS AND AUTOTAXIN IN RETINAL VEIN OCCLUSION.

Dacheva I, Ullmer C, Ceglowska K, Nogoceke E, Hartmann G, Müller S, Rejdak R, Nowomiejska K, Reich M, Nobl M, Tandogan T, Kretz FT, Auffarth GU, Koss MJ.

Retina. 2016 Dec;36(12):2311-2318.

PMID:
27648638
36.

Circular dichroism measurements at an x-ray free-electron laser with polarization control.

Hartmann G, Lindahl AO, Knie A, Hartmann N, Lutman AA, MacArthur JP, Shevchuk I, Buck J, Galler A, Glownia JM, Helml W, Huang Z, Kabachnik NM, Kazansky AK, Liu J, Marinelli A, Mazza T, Nuhn HD, Walter P, Viefhaus J, Meyer M, Moeller S, Coffee RN, Ilchen M.

Rev Sci Instrum. 2016 Aug;87(8):083113. doi: 10.1063/1.4961470.

PMID:
27587106
37.

Discriminating self from non-self in nucleic acid sensing.

Schlee M, Hartmann G.

Nat Rev Immunol. 2016 Sep;16(9):566-80. doi: 10.1038/nri.2016.78. Epub 2016 Jul 25. Review.

PMID:
27455396
38.

Inflammasome-Dependent Induction of Adaptive NK Cell Memory.

van den Boorn JG, Jakobs C, Hagen C, Renn M, Luiten RM, Melief CJ, Tüting T, Garbi N, Hartmann G, Hornung V.

Immunity. 2016 Jun 21;44(6):1406-21. doi: 10.1016/j.immuni.2016.05.008. Epub 2016 Jun 7.

39.

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice.

Ludwig-Portugall I, Bartok E, Dhana E, Evers BD, Primiano MJ, Hall JP, Franklin BS, Knolle PA, Hornung V, Hartmann G, Boor P, Latz E, Kurts C.

Kidney Int. 2016 Sep;90(3):525-39. doi: 10.1016/j.kint.2016.03.035. Epub 2016 Jun 2.

PMID:
27262364
40.

An alternative model of sexually transmissible infection testing in men attending a sex-on-premises venue in Sydney: a cross-sectional descriptive study.

Bennett C, Knight V, Knox D, Gray J, Hartmann G, McNulty A.

Sex Health. 2016 May 23. doi: 10.1071/SH15174. [Epub ahead of print]

PMID:
27208975
41.

MDA-5 activation by cytoplasmic double-stranded RNA impairs endothelial function and aggravates atherosclerosis.

Asdonk T, Steinmetz M, Krogmann A, Ströcker C, Lahrmann C, Motz I, Paul-Krahe K, Flender A, Schmitz T, Barchet W, Hartmann G, Nickenig G, Zimmer S.

J Cell Mol Med. 2016 Sep;20(9):1696-705. doi: 10.1111/jcmm.12864. Epub 2016 Apr 29.

42.

Individualized versus standardized risk assessment in patients at high risk for adverse drug reactions (IDrug) - study protocol for a pragmatic randomized controlled trial.

Stingl JC, Kaumanns KL, Claus K, Lehmann ML, Kastenmüller K, Bleckwenn M, Hartmann G, Steffens M, Wirtz D, Leuchs AK, Benda N, Meier F, Schöffski O, Holdenrieder S, Coch C, Weckbecker K.

BMC Fam Pract. 2016 Apr 26;17:49. doi: 10.1186/s12875-016-0447-6.

43.

Centennial-scale solar forcing of the South American Monsoon System recorded in stalagmites.

Novello VF, Vuille M, Cruz FW, Stríkis NM, de Paula MS, Edwards RL, Cheng H, Karmann I, Jaqueto PF, Trindade RI, Hartmann GA, Moquet JS.

Sci Rep. 2016 Apr 21;6:24762. doi: 10.1038/srep24762.

44.

Correction: ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.

Lässig C, Matheisl S, Sparrer KM, de Oliveira Mann CC, Moldt M, Patel JR, Goldeck M, Hartmann G, García-Sastre A, Hornung V, Conzelmann KK, Beckmann R, Hopfner KP.

Elife. 2016 Mar 2;5. pii: e14954. doi: 10.7554/eLife.14954. No abstract available.

45.

Cutting Edge: The RIG-I Ligand 3pRNA Potently Improves CTL Cross-Priming and Facilitates Antiviral Vaccination.

Hochheiser K, Klein M, Gottschalk C, Hoss F, Scheu S, Coch C, Hartmann G, Kurts C.

J Immunol. 2016 Mar 15;196(6):2439-43. doi: 10.4049/jimmunol.1501958. Epub 2016 Jan 27.

46.

Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice.

Hartmann G, Kumar S, Johns D, Gheyas F, Gutstein D, Shen X, Burton A, Lederman H, Lutz R, Jackson T, Chavez-Eng C, Mitra K.

Drug Metab Dispos. 2016 Mar;44(3):428-34. doi: 10.1124/dmd.115.067736. Epub 2015 Dec 28.

47.

Correction: New Archaeological Evidence for an Early Human Presence at Monte Verde, Chile.

Dillehay TD, Ocampo C, Saavedra J, Sawakuchi AO, Vega RM, Pino M, Collins MB, Cummings LS, Arregui I, Villagran XS, Hartmann GA, Mella M, González A, Dix G.

PLoS One. 2015 Dec 23;10(12):e0145471. doi: 10.1371/journal.pone.0145471. eCollection 2015. No abstract available.

48.

ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.

Lässig C, Matheisl S, Sparrer KM, de Oliveira Mann CC, Moldt M, Patel JR, Goldeck M, Hartmann G, García-Sastre A, Hornung V, Conzelmann KK, Beckmann R, Hopfner KP.

Elife. 2015 Nov 26;4. pii: e10859. doi: 10.7554/eLife.10859. Erratum in: Elife. 2016;5. pii: e14954. doi: 10.7554/eLife.14954.

49.

New Archaeological Evidence for an Early Human Presence at Monte Verde, Chile.

Dillehay TD, Ocampo C, Saavedra J, Sawakuchi AO, Vega RM, Pino M, Collins MB, Scott Cummings L, Arregui I, Villagran XS, Hartmann GA, Mella M, González A, Dix G.

PLoS One. 2015 Nov 18;10(11):e0141923. doi: 10.1371/journal.pone.0141923. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0145471.

50.

Cathepsin S Cleavage of Protease-Activated Receptor-2 on Endothelial Cells Promotes Microvascular Diabetes Complications.

Kumar Vr S, Darisipudi MN, Steiger S, Devarapu SK, Tato M, Kukarni OP, Mulay SR, Thomasova D, Popper B, Demleitner J, Zuchtriegel G, Reichel C, Cohen CD, Lindenmeyer MT, Liapis H, Moll S, Reid E, Stitt AW, Schott B, Gruner S, Haap W, Ebeling M, Hartmann G, Anders HJ.

J Am Soc Nephrol. 2016 Jun;27(6):1635-49. doi: 10.1681/ASN.2015020208. Epub 2015 Nov 13.

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