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Items: 1 to 50 of 68

1.

A natural variant and engineered mutation in a GPCR promote DEET resistance in C. elegans.

Dennis EJ, Dobosiewicz M, Jin X, Duvall LB, Hartman PS, Bargmann CI, Vosshall LB.

Nature. 2018 Oct;562(7725):119-123. doi: 10.1038/s41586-018-0546-8. Epub 2018 Sep 26.

2.

Single Plant Derived Nanotechnology for Synergistic Antibacterial Therapies.

Kalluri JR, Gonzalez-Rodriguez R, Hartman PS, Loni A, Canham LT, Coffer JL.

PLoS One. 2016 Sep 29;11(9):e0163270. doi: 10.1371/journal.pone.0163270. eCollection 2016.

3.

Endogenous reactive oxygen species cause astrocyte defects and neuronal dysfunctions in the hippocampus: a new model for aging brain.

Ishii T, Takanashi Y, Sugita K, Miyazawa M, Yanagihara R, Yasuda K, Onouchi H, Kawabe N, Nakata M, Yamamoto Y, Hartman PS, Ishii N.

Aging Cell. 2017 Feb;16(1):39-51. doi: 10.1111/acel.12523. Epub 2016 Sep 13.

4.

Infertility and recurrent miscarriage with complex II deficiency-dependent mitochondrial oxidative stress in animal models.

Ishii T, Yasuda K, Miyazawa M, Mitsushita J, Johnson TE, Hartman PS, Ishii N.

Mech Ageing Dev. 2016 Apr;155:22-35. doi: 10.1016/j.mad.2016.02.013. Epub 2016 Mar 2. Review.

PMID:
26944226
5.

Influence of Surface Chemistry on the Release of an Antibacterial Drug from Nanostructured Porous Silicon.

Wang M, Hartman PS, Loni A, Canham LT, Bodiford N, Coffer JL.

Langmuir. 2015 Jun 9;31(22):6179-85. doi: 10.1021/acs.langmuir.5b01372. Epub 2015 May 26.

PMID:
25970551
6.

Ethyl methanesulfonate induces mutations in Caenorhabditis elegans embryos at a high frequency.

Hartman PS, Barry J, Finstad W, Khan N, Tanaka M, Yasuda K, Ishii N.

Mutat Res. 2014 Aug-Sep;766-767:44-8. doi: 10.1016/j.mrfmmm.2014.05.011. Epub 2014 Jun 10.

PMID:
25847271
7.

Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans.

Arribere JA, Bell RT, Fu BX, Artiles KL, Hartman PS, Fire AZ.

Genetics. 2014 Nov;198(3):837-46. doi: 10.1534/genetics.114.169730. Epub 2014 Aug 26.

8.

Genetically induced oxidative stress in mice causes thrombocytosis, splenomegaly and placental angiodysplasia that leads to recurrent abortion.

Ishii T, Miyazawa M, Takanashi Y, Tanigawa M, Yasuda K, Onouchi H, Kawabe N, Mitsushita J, Hartman PS, Ishii N.

Redox Biol. 2014 May 14;2:679-85. doi: 10.1016/j.redox.2014.05.001. eCollection 2014.

9.

Model animals for the study of oxidative stress from complex II.

Ishii T, Miyazawa M, Onouchi H, Yasuda K, Hartman PS, Ishii N.

Biochim Biophys Acta. 2013 May;1827(5):588-97. doi: 10.1016/j.bbabio.2012.10.016. Epub 2012 Nov 6. Review.

10.

Mitochondrial superoxide anion overproduction in Tet-mev-1 transgenic mice accelerates age-dependent corneal cell dysfunctions.

Onouchi H, Ishii T, Miyazawa M, Uchino Y, Yasuda K, Hartman PS, Kawai K, Tsubota K, Ishii N.

Invest Ophthalmol Vis Sci. 2012 Aug 31;53(9):5780-7. doi: 10.1167/iovs.12-9573.

PMID:
22786907
11.

A mutation in a mitochondrial dehydrogenase/reductase gene causes an increased sensitivity to oxidative stress and mitochondrial defects in the nematode Caenorhabditis elegans.

Fujii M, Yasuda K, Hartman PS, Ayusawa D, Ishii N.

Genes Cells. 2011 Oct;16(10):1022-34. doi: 10.1111/j.1365-2443.2011.01547.x. Epub 2011 Sep 7.

12.

Mitochondrial superoxide anion (O(2)(-)) inducible "mev-1" animal models for aging research.

Ishii T, Miyazawa M, Hartman PS, Ishii N.

BMB Rep. 2011 May;44(5):298-305. doi: 10.5483/BMBRep.2011.44.5.298. Review.

13.

Interrelationships between mitochondrial fusion, energy metabolism and oxidative stress during development in Caenorhabditis elegans.

Yasuda K, Hartman PS, Ishii T, Suda H, Akatsuka A, Shoyama T, Miyazawa M, Ishii N.

Biochem Biophys Res Commun. 2011 Jan 21;404(3):751-5. doi: 10.1016/j.bbrc.2010.12.017. Epub 2010 Dec 7.

PMID:
21144829
14.

Sustained antibacterial activity from triclosan-loaded nanostructured mesoporous silicon.

Wang M, Coffer JL, Dorraj K, Hartman PS, Loni A, Canham LT.

Mol Pharm. 2010 Dec 6;7(6):2232-9. doi: 10.1021/mp100227m. Epub 2010 Nov 16.

PMID:
20973523
15.

Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation.

Ishii T, Miyazawa M, Onodera A, Yasuda K, Kawabe N, Kirinashizawa M, Yoshimura S, Maruyama N, Hartman PS, Ishii N.

Mitochondrion. 2011 Jan;11(1):155-65. doi: 10.1016/j.mito.2010.09.006. Epub 2010 Oct 18.

PMID:
20870041
16.

Post-dauer life span of Caenorhabditis elegans dauer larvae can be modified by X-irradiation.

Onodera A, Yanase S, Ishii T, Yasuda K, Miyazawa M, Hartman PS, Ishii N.

J Radiat Res. 2010;51(1):67-71. Epub 2009 Oct 23.

17.

A community perspective on quantifying the economic impact of teleradiology and telepsychiatry.

Whitacre BE, Hartman PS, Boggs SA, Schott V.

J Rural Health. 2009 Spring;25(2):194-7. doi: 10.1111/j.1748-0361.2009.00217.x. No abstract available.

PMID:
19785586
18.

The role of mitochondrial superoxide anion (O2(-)) on physiological aging in C57BL/6J mice.

Miyazawa M, Ishii T, Yasuda K, Noda S, Onouchi H, Hartman PS, Ishii N.

J Radiat Res. 2009 Jan;50(1):73-83.

19.

Repeated temperature fluctuation extends the life span of Caenorhabditis elegans in a daf-16-dependent fashion.

Galbadage T, Hartman PS.

Mech Ageing Dev. 2008 Sep;129(9):507-14. doi: 10.1016/j.mad.2008.04.012. Epub 2008 May 2.

PMID:
18538371
20.

Cell growth of the mouse SDHC mutant cells was suppressed by apoptosis throughout mitochondrial pathway.

Miyazawa M, Ishii T, Kirinashizawa M, Yasuda K, Hino O, Hartman PS, Ishii N.

Biosci Trends. 2008 Feb;2(1):22-30.

21.

Chromosome dosage as a life span determinant in Caenorhabiditis elegans.

Hartman PS, Ishii N.

Mech Ageing Dev. 2007 Jul-Aug;128(7-8):437-43. Epub 2007 Jun 19.

PMID:
17644160
22.

The role of the electron transport SDHC gene on lifespan and cancer.

Ishii N, Ishii T, Hartman PS.

Mitochondrion. 2007 Feb-Apr;7(1-2):24-8. Epub 2006 Dec 3. Review.

PMID:
17321223
23.

The role of the electron transport gene SDHC on lifespan and cancer.

Ishii N, Ishii T, Hartman PS.

Exp Gerontol. 2006 Oct;41(10):952-6. Epub 2006 Sep 7. Review.

PMID:
16962276
24.

Age-related changes of mitochondrial structure and function in Caenorhabditis elegans.

Yasuda K, Ishii T, Suda H, Akatsuka A, Hartman PS, Goto S, Miyazawa M, Ishii N.

Mech Ageing Dev. 2006 Oct;127(10):763-70. Epub 2006 Aug 7.

PMID:
16893561
25.

The p38 signal transduction pathway participates in the oxidative stress-mediated translocation of DAF-16 to Caenorhabditis elegans nuclei.

Kondo M, Yanase S, Ishii T, Hartman PS, Matsumoto K, Ishii N.

Mech Ageing Dev. 2005 Jun-Jul;126(6-7):642-7. Epub 2005 Jan 11.

PMID:
15888317
26.

Effect of oxidative stress on translocation of DAF-16 in oxygen-sensitive mutants, mev-1 and gas-1 of Caenorhabditis elegans.

Kondo M, Senoo-Matsuda N, Yanase S, Ishii T, Hartman PS, Ishii N.

Mech Ageing Dev. 2005 Jun-Jul;126(6-7):637-41. Epub 2005 Jan 8.

PMID:
15888316
27.

A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.

Ishii T, Yasuda K, Akatsuka A, Hino O, Hartman PS, Ishii N.

Cancer Res. 2005 Jan 1;65(1):203-9.

28.

Coenzyme Q10 can prolong C. elegans lifespan by lowering oxidative stress.

Ishii N, Senoo-Matsuda N, Miyake K, Yasuda K, Ishii T, Hartman PS, Furukawa S.

Mech Ageing Dev. 2004 Jan;125(1):41-6.

PMID:
14706236
29.

A complex II defect affects mitochondrial structure, leading to ced-3- and ced-4-dependent apoptosis and aging.

Senoo-Matsuda N, Hartman PS, Akatsuka A, Yoshimura S, Ishii N.

J Biol Chem. 2003 Jun 13;278(24):22031-6. Epub 2003 Apr 2.

30.

Protein oxidation during aging of the nematode Caenorhabditis elegans.

Ishii N, Goto S, Hartman PS.

Free Radic Biol Med. 2002 Oct 15;33(8):1021-5.

PMID:
12374613
31.

Enhancement of oxidative damage to cultured cells and Caenorhabditis elegans by mitochondrial electron transport inhibitors.

Ishiguro H, Yasuda K, Ishii N, Ihara K, Ohkubo T, Hiyoshi M, Ono K, Senoo-Matsuda N, Shinohara O, Yosshii F, Murakami M, Hartman PS, Tsuda M.

IUBMB Life. 2001 Apr;51(4):263-8.

32.

A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans.

Senoo-Matsuda N, Yasuda K, Tsuda M, Ohkubo T, Yoshimura S, Nakazawa H, Hartman PS, Ishii N.

J Biol Chem. 2001 Nov 9;276(45):41553-8. Epub 2001 Aug 29.

33.

Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans.

Hartman PS, Ishii N, Kayser EB, Morgan PG, Sedensky MM.

Mech Ageing Dev. 2001 Aug;122(11):1187-201.

PMID:
11389932
34.

A comparison of mutations induced by accelerated iron particles versus those induced by low earth orbit space radiation in the FEM-3 gene of Caenorhabditis elegans.

Hartman PS, Hlavacek A, Wilde H, Lewicki D, Schubert W, Kern RG, Kazarians GA, Benton EV, Benton ER, Nelson GA.

Mutat Res. 2001 Mar 1;474(1-2):47-55.

PMID:
11239962
35.

Oxidative stress and aging in Caenorhabditis elegans.

Ishii N, Hartman PS.

Results Probl Cell Differ. 2000;29:149-64. Review. No abstract available.

PMID:
10838699
36.

Isolating mutants of the nematode Caenorhabditis elegans that are hypersensitive to DNA-damaging agents.

Hartman PS, Ishii N.

Methods Mol Biol. 1999;113:11-6. No abstract available.

PMID:
10443407
37.

Oxidative stress pretreatment increases the X-radiation resistance of the nematode Caenorhabditis elegans.

Yanase S, Hartman PS, Ito A, Ishii N.

Mutat Res. 1999 May 3;426(1):31-9.

PMID:
10320748
39.

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes.

Ishii N, Fujii M, Hartman PS, Tsuda M, Yasuda K, Senoo-Matsuda N, Yanase S, Ayusawa D, Suzuki K.

Nature. 1998 Aug 13;394(6694):694-7.

PMID:
9716135
40.

Replication in UV-irradiated Caenorhabditis elegans embryos.

Jones CA, Hartman PS.

Photochem Photobiol. 1996 Feb;63(2):187-92.

PMID:
8657732
41.

Genetic and molecular analyses of UV radiation-induced mutations in the fem-3 gene of Caenorhabditis elegans.

Hartman PS, De Wilde D, Dwarakanath VN.

Photochem Photobiol. 1995 Jun;61(6):607-14.

PMID:
7568407
42.
43.
44.
45.

Transillumination can profoundly reduce transformation frequencies.

Hartman PS.

Biotechniques. 1991 Dec;11(6):747-8. No abstract available.

PMID:
1809328
46.

The regulation of DNA repair during development.

Mitchell DL, Hartman PS.

Bioessays. 1990 Feb;12(2):74-9. Review.

PMID:
2188652
47.

Excision repair of UV radiation-induced DNA damage in Caenorhabditis elegans.

Hartman PS, Hevelone J, Dwarakanath V, Mitchell DL.

Genetics. 1989 Jun;122(2):379-85.

48.

Radiation effects on life span in Caenorhabditis elegans.

Johnson TE, Hartman PS.

J Gerontol. 1988 Sep;43(5):B137-41.

PMID:
3418030
49.

An endonuclease from Caenorhabditis elegans: partial purification and characterization.

Hevelone J, Hartman PS.

Biochem Genet. 1988 Aug;26(7-8):447-61.

PMID:
3228446
50.

Radiation sensitivity and DNA repair in Caenorhabditis elegans strains with different mean life spans.

Hartman PS, Simpson VJ, Johnson T, Mitchell D.

Mutat Res. 1988 Jun;208(2):77-82.

PMID:
3380112

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