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Items: 1 to 50 of 850

1.

Thermal proteome profiling identifies oxidative-dependent inhibition of the transcription of major oncogenes as a new therapeutic mechanism for select anticancer compounds.

Peuget S, Zhu J, Sanz G, Singh M, Gaetani M, Chen X, Shi Y, Saei AA, Visnes T, Lindström MS, Rihani A, Moyano-Galceran L, Carlson JW, Hjerpe E, Joneborg U, Lehti K, Hartman J, Helleday T, Zubarev R, Selivanova G.

Cancer Res. 2020 Feb 4. pii: canres.2069.2019. doi: 10.1158/0008-5472.CAN-19-2069. [Epub ahead of print]

PMID:
32019870
2.

Seeing the world through different lenses: activity registration differs between two validated accelerometers.

van der Molen MC, Hartman JE, Vanfleteren LEGW, Slebos DJ.

ERJ Open Res. 2020 Jan 20;6(1). pii: 00262-2019. doi: 10.1183/23120541.00262-2019. eCollection 2020 Jan.

3.

Endobronchial Valve Treatment in Emphysema Patients with a Very Low DLCO.

van Dijk M, Hartman JE, Klooster K, Ten Hacken NHT, Kerstjens HAM, Slebos DJ.

Respiration. 2020;99(2):163-170. doi: 10.1159/000505428. Epub 2020 Jan 21.

4.

From Bench to Bedside: Implementation of Endobronchial Valve Treatment for Patients with Advanced Emphysema in Routine Clinical Care.

Hartman JE, Klooster K, Slebos DJ.

Respiration. 2020;99(2):187-188. doi: 10.1159/000504633. Epub 2020 Jan 15. No abstract available.

5.

In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects.

Osinski V, Bauknight DK, Dasa SSK, Harms MJ, Kroon T, Marshall MA, Garmey JC, Nguyen AT, Hartman J, Upadhye A, Srikakulapu P, Zhou A, O'Mahony G, Klibanov AL, Kelly KA, Boucher J, McNamara CA.

Theranostics. 2020 Jan 1;10(2):585-601. doi: 10.7150/thno.36572. eCollection 2020.

6.

CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance.

Langebäck A, Bacanu S, Laursen H, Mout L, Seki T, Erkens-Schulze S, Ramos AD, Berggren A, Cao Y, Hartman J, van Weerden W, Bergh J, Nordlund P, Lööf S.

Sci Rep. 2019 Dec 18;9(1):19384. doi: 10.1038/s41598-019-55526-8.

7.

FRAX prognostic and intervention thresholds in the management of major bone fractures in hemodialysis patients: A two-year prospective multicenter cohort study.

Przedlacki J, Buczyńska-Chyl J, Koźmiński P, Niemczyk E, Wojtaszek E, Gieglis E, Żebrowski P, Podgórzak A, Wściślak J, Wieliczko M, Grochowski J, Kędzierska M, Kaczanowska B, Wyszyńska A, Sitkowska-Kurzec Z, Klatko W, Gellert R, Daniewska D, Osuch D, Stryjewski D, Świtalski M, Piotrowski A, Stopiński M, Kędzierski P, Rydzewski A, Fiderkiewicz B, Wypych-Birecka M, Śliwicka D, Durlik M, Grzeszczyk M, Sokalski A, Papliński M, Hartman J, Imiela J, Małecki R, Bolesta A, Niemczyk S, Klimm W, Wierzbicki P, Gorczyńska J, Piórecki M, Gołębiewski S, Horbacz R, Małyszko J, Matuszkiewicz-Rowińska J.

Bone. 2019 Dec 13;133:115188. doi: 10.1016/j.bone.2019.115188. [Epub ahead of print]

PMID:
31843681
8.

Early postnatal manganese exposure causes arousal dysregulation and lasting hypofunctioning of the prefrontal cortex catecholaminergic systems.

Conley TE, Beaudin SA, Lasley SM, Fornal CA, Hartman J, Uribe W, Khan T, Strupp BJ, Smith DR.

J Neurochem. 2019 Dec 7:e14934. doi: 10.1111/jnc.14934. [Epub ahead of print]

PMID:
31811785
9.

The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay.

Beames T, Moreau M, Roberts LA, Mansouri K, Haider S, Smeltz M, Nicolas CI, Doheny D, Phillips MB, Yoon M, Becker RA, McMullen PD, Andersen ME, Clewell RA, Hartman JK.

Toxicol Appl Pharmacol. 2020 Jan 15;387:114774. doi: 10.1016/j.taap.2019.114774. Epub 2019 Nov 27.

10.

Structure-Activity Relationships of 7-Substituted Dimethyltyrosine-Tetrahydroisoquinoline Opioid Peptidomimetics.

Montgomery D, Anand JP, Baber MA, Twarozynski JJ, Hartman JG, Delong LJ, Traynor JR, Mosberg HI.

Molecules. 2019 Nov 26;24(23). pii: E4302. doi: 10.3390/molecules24234302.

11.

CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment.

Neo SY, Yang Y, Record J, Ma R, Chen X, Chen Z, Tobin NP, Blake E, Seitz C, Thomas R, Wagner AK, Andersson J, de Boniface J, Bergh J, Murray S, Alici E, Childs R, Johansson M, Westerberg LS, Haglund F, Hartman J, Lundqvist A.

J Clin Invest. 2020 Feb 4. pii: 128895. doi: 10.1172/JCI128895. [Epub ahead of print]

12.

Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects.

Bauknight DK, Osinski V, Dasa SSK, Nguyen AT, Marshall MA, Hartman J, Harms M, O'Mahony G, Boucher J, Klibanov AL, McNamara CA, Kelly KA.

PLoS One. 2019 Nov 14;14(11):e0224917. doi: 10.1371/journal.pone.0224917. eCollection 2019.

13.

Swim exercise in Caenorhabditis elegans extends neuromuscular and gut healthspan, enhances learning ability, and protects against neurodegeneration.

Laranjeiro R, Harinath G, Hewitt JE, Hartman JH, Royal MA, Meyer JN, Vanapalli SA, Driscoll M.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23829-23839. doi: 10.1073/pnas.1909210116. Epub 2019 Nov 4.

14.

Computational study of clot formation in aneurysms treated with shape memory polymer foam.

Horn JD, Maitland DJ, Hartman J, Ortega JM.

Med Eng Phys. 2020 Jan;75:65-71. doi: 10.1016/j.medengphy.2019.10.002. Epub 2019 Oct 28.

PMID:
31672456
15.

Developing context appropriate toxicity testing approaches using new alternative methods (NAMs).

Andersen ME, McMullen PD, Phillips MB, Yoon M, Pendse SN, Clewell HJ, Hartman JK, Moreau M, Becker RA, Clewell RA.

ALTEX. 2019;36(4):523-534. doi: 10.14573/altex.1906261.

16.

A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin.

Santos SM, Hartman JL 4th.

Cancer Metab. 2019 Oct 23;7:9. doi: 10.1186/s40170-019-0201-3. eCollection 2019.

17.

Slowing ribosome velocity restores folding and function of mutant CFTR.

Oliver KE, Rauscher R, Mijnders M, Wang W, Wolpert MJ, Maya J, Sabusap CM, Kesterson RA, Kirk KL, Rab A, Braakman I, Hong JS, Hartman JL 4th, Ignatova Z, Sorscher EJ.

J Clin Invest. 2019 Dec 2;129(12):5236-5253. doi: 10.1172/JCI124282.

18.

Cauda Equina Syndrome in a Patient with Intradural Schwannoma at the Same Level as an Acute L2 Compression Fracture.

Mallol D, Taveras R, Hartman J, Granville M, Jacobson RE.

Cureus. 2019 Aug 26;11(8):e5492. doi: 10.7759/cureus.5492.

19.

CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples.

Zhang X, Garnerone S, Simonetti M, Harbers L, Nicoś M, Mirzazadeh R, Venesio T, Sapino A, Hartman J, Marchiò C, Bienko M, Crosetto N.

Nat Commun. 2019 Oct 18;10(1):4732. doi: 10.1038/s41467-019-12570-2.

20.

The Use of Vertiflex® Interspinous Spacer Device in Patients With Lumbar Spinal Stenosis and Concurrent Medical Comorbidities.

Hartman J, Granville M, Jacobson RE.

Cureus. 2019 Aug 12;11(8):e5374. doi: 10.7759/cureus.5374.

21.

Democratized image analytics by visual programming through integration of deep models and small-scale machine learning.

Godec P, Pančur M, Ilenič N, Čopar A, Stražar M, Erjavec A, Pretnar A, Demšar J, Starič A, Toplak M, Žagar L, Hartman J, Wang H, Bellazzi R, Petrovič U, Garagna S, Zuccotti M, Park D, Shaulsky G, Zupan B.

Nat Commun. 2019 Oct 7;10(1):4551. doi: 10.1038/s41467-019-12397-x.

22.

A Humanized Yeast Phenomic Model of Deoxycytidine Kinase to Predict Genetic Buffering of Nucleoside Analog Cytotoxicity.

Santos SM, Icyuz M, Pound I, William D, Guo J, McKinney BA, Niederweis M, Rodgers J, Hartman JL IV.

Genes (Basel). 2019 Sep 30;10(10). pii: E770. doi: 10.3390/genes10100770.

23.

Physical Therapists Needed: The Refugee Crisis in Greece and Our Ethical Responsibility to Respond.

Schottland-Cox J, Hartman J.

Phys Ther. 2019 Dec 16;99(12):1583-1586. doi: 10.1093/ptj/pzz128. No abstract available.

PMID:
31504927
24.

A New Oxygen Uptake Measurement Supporting Target Selection for Endobronchial Valve Treatment.

Welling JBA, Klooster K, Charbonnier JP, Van Rikxoort EM, Barends CRM, Kerstjens HAM, Ten Hacken NHT, Hartman JE, Slebos DJ.

Respiration. 2019;98(6):521-526. doi: 10.1159/000502310. Epub 2019 Sep 3.

25.

Significant Differences in Body Plethysmography Measurements Between Hospitals in Patients Referred for Bronchoscopic Lung Volume Reduction.

Welling JBA, Hartman JE, Ten Hacken NHT, Augustijn SWS, Kerstjens HAM, Slebos DJ, Klooster K.

Lung. 2019 Oct;197(5):573-576. doi: 10.1007/s00408-019-00265-w. Epub 2019 Aug 31.

PMID:
31473796
26.

Next generation pathology: artificial intelligence enhances histopathology practice.

Acs B, Hartman J.

J Pathol. 2020 Jan;250(1):7-8. doi: 10.1002/path.5343. Epub 2019 Oct 23.

PMID:
31465119
27.

Collateral Ventilation Measurement Using Chartis: Procedural Sedation vs General Anesthesia.

Welling JBA, Klooster K, Hartman JE, Kerstjens HAM, Franz I, Struys MMRF, Absalom AR, Slebos DJ, Barends CRM.

Chest. 2019 Nov;156(5):984-990. doi: 10.1016/j.chest.2019.07.025. Epub 2019 Aug 15.

PMID:
31421111
28.

Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe Chronic Obstructive Pulmonary Disease (AIRFLOW). A Multicenter Randomized Controlled Clinical Trial.

Slebos DJ, Shah PL, Herth FJF, Pison C, Schumann C, Hübner RH, Bonta PI, Kessler R, Gesierich W, Darwiche K, Lamprecht B, Perez T, Skowasch D, Deslee G, Marceau A, Sciurba FC, Gosens R, Hartman JE, Srikanthan K, Duller M, Valipour A; AIRFLOW-2 Study Group.

Am J Respir Crit Care Med. 2019 Dec 15;200(12):1477-1486. doi: 10.1164/rccm.201903-0624OC.

29.

PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.

Costa TDF, Zhuang T, Lorent J, Turco E, Olofsson H, Masia-Balague M, Zhao M, Rabieifar P, Robertson N, Kuiper R, Sjölund J, Spiess M, Hernández-Varas P, Rabenhorst U, Roswall P, Ma R, Gong X, Hartman J, Pietras K, Adams PD, Defilippi P, Strömblad S.

Nat Commun. 2019 Aug 9;10(1):3589. doi: 10.1038/s41467-019-11510-4.

30.

Effect of Adding a Pediatric Vascular Access Team Component to a Pediatric Peripheral Vascular Access Algorithm.

Hartman JH, Bena JF, Morrison SL, Albert NM.

J Pediatr Health Care. 2020 Jan - Feb;34(1):4-9. doi: 10.1016/j.pedhc.2019.06.004. Epub 2019 Jul 31.

PMID:
31375309
31.

Erratum to: iMicrobe: Tools and data-driven discovery platform for the microbiome sciences.

Youens-Clark K, Bomhoff M, Ponsero AJ, Wood-Charlson EM, Lynch J, Choi I, Hartman JH, Hurwitz BL.

Gigascience. 2019 Aug 1;8(8). pii: giz097. doi: 10.1093/gigascience/giz097. No abstract available.

32.

Does Device or Connection Type Affect Health Preferences in Online Surveys?

Hartman JD, Craig BM.

Patient. 2019 Dec;12(6):639-650. doi: 10.1007/s40271-019-00380-z.

PMID:
31364022
33.

Treatment of a High-risk Thoracolumbar Compression Fracture Using Bilateral Expandable Titanium SpineJack Implants.

Hartman J, Granville M, Jacobson RE.

Cureus. 2019 May 21;11(5):e4701. doi: 10.7759/cureus.4701.

34.

Strengths and limitations of morphological and behavioral analyses in detecting dopaminergic deficiency in Caenorhabditis elegans.

Smith LL, Ryde IT, Hartman JH, Romersi RF, Markovich Z, Meyer JN.

Neurotoxicology. 2019 Sep;74:209-220. doi: 10.1016/j.neuro.2019.07.002. Epub 2019 Jul 16.

PMID:
31323240
35.

iMicrobe: Tools and data-dreaiven discovery platform for the microbiome sciences.

Youens-Clark K, Bomhoff M, Ponsero AJ, Wood-Charlson EM, Lynch J, Choi I, Hartman JH, Hurwitz BL.

Gigascience. 2019 Jul 1;8(7). pii: giz083. doi: 10.1093/gigascience/giz083. Erratum in: Gigascience. 2019 Aug 1;8(8):.

36.

Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration.

Hartman JH, Gonzalez-Hunt C, Hall SM, Ryde IT, Caldwell KA, Caldwell GA, Meyer JN.

Int J Mol Sci. 2019 Jun 29;20(13). pii: E3202. doi: 10.3390/ijms20133202.

38.

Open source acoustofluidics.

Bachman H, Fu H, Huang PH, Tian Z, Embry-Seckler J, Rufo J, Xie Z, Hartman JH, Zhao S, Yang S, Meyer JN, Huang TJ.

Lab Chip. 2019 Jul 21;19(14):2404-2414. doi: 10.1039/c9lc00340a. Epub 2019 Jun 26.

39.

Safety and Dose Study of Targeted Lung Denervation in Moderate/Severe COPD Patients.

Valipour A, Shah PL, Pison C, Ninane V, Janssens W, Perez T, Kessler R, Deslee G, Garner J, Abele C, Hartman JE, Slebos DJ; On behalf of the AIRFLOW-1 Study Group.

Respiration. 2019;98(4):329-339. doi: 10.1159/000500463. Epub 2019 Jun 20.

40.

Novel Dimethyltyrosine-Tetrahydroisoquinoline Peptidomimetics with Aromatic Tetrahydroisoquinoline Substitutions Show in Vitro Kappa and Mu Opioid Receptor Agonism.

Montgomery D, Anand JP, Griggs NW, Fernandez TJ, Hartman JG, Sánchez-Santiago AA, Pogozheva ID, Traynor JR, Mosberg HI.

ACS Chem Neurosci. 2019 Aug 21;10(8):3682-3689. doi: 10.1021/acschemneuro.9b00250. Epub 2019 Jul 1.

41.
42.

MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa.

Hartman JH, Richie CT, Gordon KL, Mello DF, Castillo P, Zhu A, Wang Y, Hoffer BJ, Sherwood DR, Meyer JN, Harvey BK.

Eur J Cell Biol. 2019 Dec;98(5-8). pii: S0171-9335(18)30348-0. doi: 10.1016/j.ejcb.2019.05.002. Epub 2019 May 21.

PMID:
31138438
43.

EMPIRICAL TIDAL DISSIPATION IN EXOPLANET HOSTS FROM TIDAL SPIN-UP.

Penev K, Bouma LG, Winn JN, Hartman JD.

Astron J. 2018 Apr;155(4). pii: 165. doi: 10.3847/1538-3881/aaaf71. Epub 2018 Mar 22.

44.

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.

Prakash V, Carson BB, Feenstra JM, Dass RA, Sekyrova P, Hoshino A, Petersen J, Guo Y, Parks MM, Kurylo CM, Batchelder JE, Haller K, Hashimoto A, Rundqivst H, Condeelis JS, Allis CD, Drygin D, Nieto MA, Andäng M, Percipalle P, Bergh J, Adameyko I, Farrants AÖ, Hartman J, Lyden D, Pietras K, Blanchard SC, Vincent CT.

Nat Commun. 2019 May 8;10(1):2110. doi: 10.1038/s41467-019-10100-8.

45.

Endobronchial valves for severe emphysema.

Hartman JE, Vanfleteren LEGW, van Rikxoort EM, Klooster K, Slebos DJ.

Eur Respir Rev. 2019 Apr 17;28(152). pii: 180121. doi: 10.1183/16000617.0121-2018. Print 2019 Jun 30. Review.

46.

Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity.

Latifkar A, Ling L, Hingorani A, Johansen E, Clement A, Zhang X, Hartman J, Fischbach C, Lin H, Cerione RA, Antonyak MA.

Dev Cell. 2019 May 6;49(3):393-408.e7. doi: 10.1016/j.devcel.2019.03.011. Epub 2019 Apr 11.

PMID:
30982660
47.

Collaboration between patient and pharmacovigilance organizations to gain insight into adults' experiences with drug use and ADRs for the treatment of ADHD.

Weits G, Härmark L, Hartman J, Kant A.

Expert Opin Drug Saf. 2019 Apr;18(4):333-337. doi: 10.1080/14740338.2019.1591366. Epub 2019 Mar 14.

PMID:
30845849
48.

Predictors of Response to Endobronchial Coil Therapy in Patients With Advanced Emphysema.

Slebos DJ, Cicenia J, Sciurba FC, Criner GJ, Hartman JE, Garner J, Deslée G, Delage A, Jantz M, Marquette CH, Strange C, Hatipoglu U, Mehta AC, LaPrad AS, Schmid-Bindert G, Herth FJF, Shah PL; RENEW Study Group.

Chest. 2019 May;155(5):928-937. doi: 10.1016/j.chest.2019.02.012. Epub 2019 Feb 21.

PMID:
30797746
49.

Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans.

Zhang J, Yang S, Chen C, Hartman JH, Huang PH, Wang L, Tian Z, Zhang P, Faulkenberry D, Meyer JN, Huang TJ.

Lab Chip. 2019 Mar 13;19(6):984-992. doi: 10.1039/c8lc01012a.

50.

Blinded Visual Scoring of Images Using the Freely-available Software Blinder.

Cothren SD, Meyer JN, Hartman JH.

Bio Protoc. 2018 Dec 5;8(23). pii: e3103. doi: 10.21769/BioProtoc.3103.

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