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Items: 21


Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling.

Hansen M, Peltier J, Killy B, Amin B, Bodendorfer B, Härtlova A, Uebel S, Bosmann M, Hofmann J, Büttner C, Ekici AB, Kuttke M, Franzyk H, Foged C, Beer-Hammer S, Schabbauer G, Trost M, Lang R.

Mol Cell Proteomics. 2019 Jan 11. pii: mcp.RA118.000929. doi: 10.1074/mcp.RA118.000929. [Epub ahead of print]


Regulation of phagosome functions by post-translational modifications: a new paradigm.

Dean P, Heunis T, Härtlova A, Trost M.

Curr Opin Chem Biol. 2018 Nov 24;48:73-80. doi: 10.1016/j.cbpa.2018.11.001. [Epub ahead of print] Review.


LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.

Härtlova A, Herbst S, Peltier J, Rodgers A, Bilkei-Gorzo O, Fearns A, Dill BD, Lee H, Flynn R, Cowley SA, Davies P, Lewis PA, Ganley IG, Martinez J, Alessi DR, Reith AD, Trost M, Gutierrez MG.

EMBO J. 2018 Jun 15;37(12). pii: e98694. doi: 10.15252/embj.201798694. Epub 2018 May 22.


Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib.

Miettinen TP, Peltier J, Härtlova A, Gierliński M, Jansen VM, Trost M, Björklund M.

EMBO J. 2018 May 15;37(10). pii: e98359. doi: 10.15252/embj.201798359. Epub 2018 Apr 18.


Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti-Bacterial Innate Immunity.

Erttmann SF, Härtlova A, Sloniecka M, Raffi FAM, Hosseinzadeh A, Edgren T, Rofougaran R, Resch U, Fällman M, Ek T, Gekara NO.

Immunity. 2017 Dec 19;47(6):1210-1211. doi: 10.1016/j.immuni.2017.11.014. No abstract available.


Subversion of innate immune responses by Francisella involves the disruption of TRAF3 and TRAF6 signalling complexes.

Putzova D, Panda S, Härtlova A, Stulík J, Gekara NO.

Cell Microbiol. 2017 Nov;19(11). doi: 10.1111/cmi.12769. Epub 2017 Aug 16.


Assessing the Phagosome Proteome by Quantitative Mass Spectrometry.

Peltier J, Härtlova A, Trost M.

Methods Mol Biol. 2017;1519:249-263.


Isolation and Western Blotting of Latex-Bead Phagosomes to Track Phagosome Maturation.

Härtlova A, Peltier J, Bilkei-Gorzo O, Trost M.

Methods Mol Biol. 2017;1519:241-248.


Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti-Bacterial Innate Immunity.

Erttmann SF, Härtlova A, Sloniecka M, Raffi FA, Hosseinzadeh A, Edgren T, Rofougaran R, Resch U, Fällman M, Ek T, Gekara NO.

Immunity. 2016 Jul 19;45(1):106-18. doi: 10.1016/j.immuni.2016.06.018. Epub 2016 Jul 12. Erratum in: Immunity. 2017 Dec 19;47(6):1210-1211.


A mass spectrometric-derived cell surface protein atlas.

Bausch-Fluck D, Hofmann A, Bock T, Frei AP, Cerciello F, Jacobs A, Moest H, Omasits U, Gundry RL, Yoon C, Schiess R, Schmidt A, Mirkowska P, Härtlová A, Van Eyk JE, Bourquin JP, Aebersold R, Boheler KR, Zandstra P, Wollscheid B.

PLoS One. 2015 Apr 20;10(3):e0121314. doi: 10.1371/journal.pone.0121314. eCollection 2015.


Quantitative proteome analysis of temporally resolved phagosomes following uptake via key phagocytic receptors.

Dill BD, Gierlinski M, Härtlova A, Arandilla AG, Guo M, Clarke RG, Trost M.

Mol Cell Proteomics. 2015 May;14(5):1334-49. doi: 10.1074/mcp.M114.044594. Epub 2015 Mar 9.


DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity.

Härtlova A, Erttmann SF, Raffi FA, Schmalz AM, Resch U, Anugula S, Lienenklaus S, Nilsson LM, Kröger A, Nilsson JA, Ek T, Weiss S, Gekara NO.

Immunity. 2015 Feb 17;42(2):332-343. doi: 10.1016/j.immuni.2015.01.012.


High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived macrophages.

Guo M, Härtlova A, Dill BD, Prescott AR, Gierliński M, Trost M.

Proteomics. 2015 Sep;15(18):3169-74. doi: 10.1002/pmic.201400431. Epub 2015 Feb 5.


Quantitative proteomics analysis of macrophage-derived lipid rafts reveals induction of autophagy pathway at the early time of Francisella tularensis LVS infection.

Härtlova A, Link M, Balounova J, Benesova M, Resch U, Straskova A, Sobol M, Philimonenko A, Hozak P, Krocova Z, Gekara N, Filipp D, Stulik J.

J Proteome Res. 2014 Feb 7;13(2):796-804. doi: 10.1021/pr4008656. Epub 2014 Jan 7.


Application of SILAC labeling to primary bone marrow-derived dendritic cells reveals extensive GM-CSF-dependent arginine metabolism.

Fabrik I, Link M, Härtlova A, Dankova V, Rehulka P, Stulik J.

J Proteome Res. 2014 Feb 7;13(2):752-62. doi: 10.1021/pr4007798. Epub 2013 Dec 17.


Serving the new masters - dendritic cells as hosts for stealth intracellular bacteria.

Fabrik I, Härtlova A, Rehulka P, Stulik J.

Cell Microbiol. 2013 Sep;15(9):1473-83. doi: 10.1111/cmi.12160. Epub 2013 Jul 29. Review.


Tetratricopeptide repeat motifs in the world of bacterial pathogens: role in virulence mechanisms.

Cerveny L, Straskova A, Dankova V, Hartlova A, Ceckova M, Staud F, Stulik J.

Infect Immun. 2013 Mar;81(3):629-35. doi: 10.1128/IAI.01035-12. Epub 2012 Dec 21. Review.


A proteomic view of the host-pathogen interaction: The host perspective.

Hartlova A, Krocova Z, Cerveny L, Stulik J.

Proteomics. 2011 Aug;11(15):3212-20. doi: 10.1002/pmic.201000767. Epub 2011 Jul 4. Review.


Activation of B cell apoptotic pathways in the course of Francisella tularensis infection.

Zivna L, Krocova Z, Härtlova A, Kubelkova K, Zakova J, Rudolf E, Hrstka R, Macela A, Stulik J.

Microb Pathog. 2010 Nov;49(5):226-36. doi: 10.1016/j.micpath.2010.06.003. Epub 2010 Jun 23.


Membrane rafts: a potential gateway for bacterial entry into host cells.

Hartlova A, Cerveny L, Hubalek M, Krocova Z, Stulik J.

Microbiol Immunol. 2010 Apr;54(4):237-45. doi: 10.1111/j.1348-0421.2010.00198.x. Review.


Interaction of B cells with intracellular pathogen Francisella tularensis.

Krocova Z, Härtlova A, Souckova D, Zivna L, Kroca M, Rudolf E, Macela A, Stulik J.

Microb Pathog. 2008 Aug;45(2):79-85. doi: 10.1016/j.micpath.2008.01.010. Epub 2008 Apr 8.


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