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Items: 8


Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma.

Purzner T, Purzner J, Buckstaff T, Cozza G, Gholamin S, Rusert JM, Hartl TA, Sanders J, Conley N, Ge X, Langan M, Ramaswamy V, Ellis L, Litzenburger U, Bolin S, Theruvath J, Nitta R, Qi L, Li XN, Li G, Taylor MD, Wechsler-Reya RJ, Pinna LA, Cho YJ, Fuller MT, Elias JE, Scott MP.

Sci Signal. 2018 Sep 11;11(547). pii: eaau5147. doi: 10.1126/scisignal.aau5147.


Stable Chromosome Condensation Revealed by Chromosome Conformation Capture.

Eagen KP, Hartl TA, Kornberg RD.

Cell. 2015 Nov 5;163(4):934-46. doi: 10.1016/j.cell.2015.10.026.


Wing tips: The wing disc as a platform for studying Hedgehog signaling.

Hartl TA, Scott MP.

Methods. 2014 Jun 15;68(1):199-206. doi: 10.1016/j.ymeth.2014.02.002. Epub 2014 Feb 17. Review.


Maintenance of interphase chromosome compaction and homolog pairing in Drosophila is regulated by the condensin cap-h2 and its partner Mrg15.

Smith HF, Roberts MA, Nguyen HQ, Peterson M, Hartl TA, Wang XJ, Klebba JE, Rogers GC, Bosco G.

Genetics. 2013 Sep;195(1):127-46. doi: 10.1534/genetics.113.153544. Epub 2013 Jul 2.


Regulation of ribosome biogenesis by nucleostemin 3 promotes local and systemic growth in Drosophila.

Hartl TA, Ni J, Cao J, Suyama KL, Patchett S, Bussiere C, Gui DY, Tang S, Kaplan DD, Fish M, Johnson AW, Scott MP.

Genetics. 2013 May;194(1):101-15. doi: 10.1534/genetics.112.149104. Epub 2013 Feb 22.


Condensin II promotes the formation of chromosome territories by inducing axial compaction of polyploid interphase chromosomes.

Bauer CR, Hartl TA, Bosco G.

PLoS Genet. 2012;8(8):e1002873. doi: 10.1371/journal.pgen.1002873. Epub 2012 Aug 30.


Chromosome alignment and transvection are antagonized by condensin II.

Hartl TA, Smith HF, Bosco G.

Science. 2008 Nov 28;322(5906):1384-7. doi: 10.1126/science.1164216.


Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis.

Hartl TA, Sweeney SJ, Knepler PJ, Bosco G.

PLoS Genet. 2008 Oct;4(10):e1000228. doi: 10.1371/journal.pgen.1000228. Epub 2008 Oct 17.

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