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Items: 1 to 50 of 380

1.

A macrocyclic receptor containing two viologen species connected by conjugated terphenyl groups.

Chen L, Lim KJC, Babra TS, Taylor JO, PiŽl M, Evans R, Chippindale AM, Hartl F, Colquhoun HM, Greenland BW.

Org Biomol Chem. 2018 Jul 11;16(27):5006-5015. doi: 10.1039/c8ob00919h.

PMID:
29946600
2.

Anodic electrochemistry of mono- and dinuclear aminophenylferrocene and diphenylaminoferrocene complexes.

Zhang MX, Zhang J, Yin J, Hartl F, Liu SH.

Dalton Trans. 2018 May 1;47(17):6112-6123. doi: 10.1039/c8dt00584b.

PMID:
29664488
3.

Molecular and structural architecture of polyQ aggregates in yeast.

Gruber A, Hornburg D, Antonin M, Krahmer N, Collado J, Schaffer M, Zubaite G, Lüchtenborg C, Sachsenheimer T, Brügger B, Mann M, Baumeister W, Hartl FU, Hipp MS, Fernández-Busnadiego R.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3446-E3453. doi: 10.1073/pnas.1717978115. Epub 2018 Mar 26.

PMID:
29581260
4.

Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.

Prestipino A, Emhardt AJ, Aumann K, O'Sullivan D, Gorantla SP, Duquesne S, Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M, Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R.

Sci Transl Med. 2018 Feb 21;10(429). pii: eaam7729. doi: 10.1126/scitranslmed.aam7729.

PMID:
29467301
5.

In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.

Guo Q, Lehmer C, Martínez-Sánchez A, Rudack T, Beck F, Hartmann H, Pérez-Berlanga M, Frottin F, Hipp MS, Hartl FU, Edbauer D, Baumeister W, Fernández-Busnadiego R.

Cell. 2018 Feb 8;172(4):696-705.e12. doi: 10.1016/j.cell.2017.12.030. Epub 2018 Feb 1.

6.

GroEL Ring Separation and Exchange in the Chaperonin Reaction.

Yan X, Shi Q, Bracher A, Miličić G, Singh AK, Hartl FU, Hayer-Hartl M.

Cell. 2018 Jan 25;172(3):605-617.e11. doi: 10.1016/j.cell.2017.12.010. Epub 2018 Jan 11.

PMID:
29336887
7.

High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins.

Vincenz-Donnelly L, Holthusen H, Körner R, Hansen EC, Presto J, Johansson J, Sawarkar R, Hartl FU, Hipp MS.

EMBO J. 2018 Feb 1;37(3):337-350. doi: 10.15252/embj.201695841. Epub 2017 Dec 15.

PMID:
29247078
8.

Plant RuBisCo assembly in E. coli with five chloroplast chaperones including BSD2.

Aigner H, Wilson RH, Bracher A, Calisse L, Bhat JY, Hartl FU, Hayer-Hartl M.

Science. 2017 Dec 8;358(6368):1272-1278. doi: 10.1126/science.aap9221.

PMID:
29217567
9.

Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function.

Hosp F, Gutiérrez-Ángel S, Schaefer MH, Cox J, Meissner F, Hipp MS, Hartl FU, Klein R, Dudanova I, Mann M.

Cell Rep. 2017 Nov 21;21(8):2291-2303. doi: 10.1016/j.celrep.2017.10.097.

10.

Structural Variability of 4f and 5f Thiocyanate Complexes and Dissociation of Uranium(III)-Thiocyanate Bonds with Increased Ionicity.

Biswas S, Ma S, Nuzzo S, Twamley B, Russell AT, Platts JA, Hartl F, Baker RJ.

Inorg Chem. 2017 Dec 4;56(23):14426-14437. doi: 10.1021/acs.inorgchem.7b01560. Epub 2017 Nov 16.

PMID:
29144747
11.

Pathways of cellular proteostasis in aging and disease.

Klaips CL, Jayaraj GG, Hartl FU.

J Cell Biol. 2018 Jan 2;217(1):51-63. doi: 10.1083/jcb.201709072. Epub 2017 Nov 10. Review.

12.

Cytosolic Protein Vms1 Links Ribosome Quality Control to Mitochondrial and Cellular Homeostasis.

Izawa T, Park SH, Zhao L, Hartl FU, Neupert W.

Cell. 2017 Nov 2;171(4):890-903.e18. doi: 10.1016/j.cell.2017.10.002. Epub 2017 Oct 26.

PMID:
29107329
13.

Unfolding the chaperone story.

Hartl FU.

Mol Biol Cell. 2017 Nov 1;28(22):2919-2923. doi: 10.1091/mbc.E17-07-0480.

14.

In Situ Architecture and Cellular Interactions of PolyQ Inclusions.

Bäuerlein FJB, Saha I, Mishra A, Kalemanov M, Martínez-Sánchez A, Klein R, Dudanova I, Hipp MS, Hartl FU, Baumeister W, Fernández-Busnadiego R.

Cell. 2017 Sep 21;171(1):179-187.e10. doi: 10.1016/j.cell.2017.08.009. Epub 2017 Sep 7.

PMID:
28890085
15.

Role of the ribosomal quality control machinery in nucleocytoplasmic translocation of polyQ-expanded huntingtin exon-1.

Zheng J, Yang J, Choe YJ, Hao X, Cao X, Zhao Q, Zhang Y, Franssens V, Hartl FU, Nyström T, Winderickx J, Liu B.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):708-717. doi: 10.1016/j.bbrc.2017.08.126. Epub 2017 Aug 30.

16.

Bonding and Electronic Properties of Linear Diethynyl Oligothienoacene-Bridged Diruthenium Complexes and Their Oxidized Forms.

Ou YP, Zhang J, Zhang MX, Zhang F, Kuang D, Hartl F, Liu SH.

Inorg Chem. 2017 Sep 18;56(18):11074-11086. doi: 10.1021/acs.inorgchem.7b01433. Epub 2017 Aug 29.

PMID:
28849928
17.

Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance.

Minguet S, Kläsener K, Schaffer AM, Fiala GJ, Osteso-Ibánez T, Raute K, Navarro-Lérida I, Hartl FA, Seidl M, Reth M, Del Pozo MA.

Nat Immunol. 2017 Oct;18(10):1150-1159. doi: 10.1038/ni.3813. Epub 2017 Aug 14.

18.

Mechanism of Enzyme Repair by the AAA+ Chaperone Rubisco Activase.

Bhat JY, Miličić G, Thieulin-Pardo G, Bracher A, Maxwell A, Ciniawsky S, Mueller-Cajar O, Engen JR, Hartl FU, Wendler P, Hayer-Hartl M.

Mol Cell. 2017 Sep 7;67(5):744-756.e6. doi: 10.1016/j.molcel.2017.07.004. Epub 2017 Aug 10.

PMID:
28803776
19.

New Multiresponsive Chromic Soft Materials: Dynamic Interconversion of Short 2,7-Dicyanomethylenecarbazole-Based Biradicaloid and the Corresponding Cyclophane Tetramer.

Wang D, Capel Ferrón C, Li J, Gámez-Valenzuela S, Ponce Ortiz R, López Navarrete JT, Hernández Jolín V, Yang X, Peña Álvarez M, García Baonza V, Hartl F, Ruiz Delgado MC, Li H.

Chemistry. 2017 Oct 4;23(55):13776-13783. doi: 10.1002/chem.201702659. Epub 2017 Sep 5.

PMID:
28749543
20.

Rubisco Activases: AAA+ Chaperones Adapted to Enzyme Repair.

Bhat JY, Thieulin-Pardo G, Hartl FU, Hayer-Hartl M.

Front Mol Biosci. 2017 Apr 10;4:20. doi: 10.3389/fmolb.2017.00020. eCollection 2017. Review.

21.

Protein Misfolding Diseases.

Hartl FU.

Annu Rev Biochem. 2017 Jun 20;86:21-26. doi: 10.1146/annurev-biochem-061516-044518. Epub 2017 Apr 24.

PMID:
28441058
22.

Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

Walther DM, Kasturi P, Zheng M, Pinkert S, Vecchi G, Ciryam P, Morimoto RI, Dobson CM, Vendruscolo M, Mann M, Hartl FU.

Cell. 2017 Feb 23;168(5):944. doi: 10.1016/j.cell.2016.12.041. No abstract available.

23.

Biogenesis and Metabolic Maintenance of Rubisco.

Bracher A, Whitney SM, Hartl FU, Hayer-Hartl M.

Annu Rev Plant Biol. 2017 Apr 28;68:29-60. doi: 10.1146/annurev-arplant-043015-111633. Epub 2017 Jan 11. Review.

PMID:
28125284
24.

Sandwich and half-sandwich metal complexes derived from cross-conjugated 3-methylene-penta-1,4-diynes.

Vincent KB, Gluyas JBG, Zeng Q, Yufit DS, Howard JAK, Hartl F, Low PJ.

Dalton Trans. 2017 May 2;46(17):5522-5531. doi: 10.1039/c6dt04470k.

PMID:
28054684
25.

Multistep Oxidation of Diethynyl Oligophenylamine-Bridged Diruthenium and Diiron Complexes.

Zhang J, Guo SZ, Dong YB, Rao L, Yin J, Yu GA, Hartl F, Liu SH.

Inorg Chem. 2017 Jan 17;56(2):1001-1015. doi: 10.1021/acs.inorgchem.6b02809. Epub 2017 Jan 3.

PMID:
28045545
26.

Diacenaphthylene-fused benzo[1,2-b:4,5-b']dithiophenes: polycyclic heteroacenes containing full-carbon five-membered aromatic rings.

Wu H, Fang R, Tao J, Wang D, Qiao X, Yang X, Hartl F, Li H.

Chem Commun (Camb). 2017 Jan 5;53(4):751-754. doi: 10.1039/c6cc09184a.

PMID:
27995232
27.

Manganese Tricarbonyl Complexes with Asymmetric 2-Iminopyridine Ligands: Toward Decoupling Steric and Electronic Factors in Electrocatalytic CO2 Reduction.

Spall SJ, Keane T, Tory J, Cocker DC, Adams H, Fowler H, Meijer AJ, Hartl F, Weinstein JA.

Inorg Chem. 2016 Dec 19;55(24):12568-12582. Epub 2016 Nov 23.

PMID:
27989199
28.

Susan Lee Lindquist (1949-2016)-pioneer in the study of cellular protein folding and disease.

Hartl FU.

EMBO J. 2016 Dec 15;35(24):2626-2627. Epub 2016 Dec 5. No abstract available.

29.

Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors.

Kim YE, Hosp F, Frottin F, Ge H, Mann M, Hayer-Hartl M, Hartl FU.

Mol Cell. 2016 Sep 15;63(6):951-64. doi: 10.1016/j.molcel.2016.07.022. Epub 2016 Aug 25.

30.

Localized Mixed-Valence and Redox Activity within a Triazole-Bridged Dinucleating Ligand upon Coordination to Palladium.

Broere DL, Plessius R, Tory J, Demeshko S, de Bruin B, Siegler MA, Hartl F, van der Vlugt JI.

Chemistry. 2016 Sep 19;22(39):13965-13975. doi: 10.1002/chem.201601900. Epub 2016 Aug 17.

PMID:
27531163
31.

In vivo aspects of protein folding and quality control.

Balchin D, Hayer-Hartl M, Hartl FU.

Science. 2016 Jul 1;353(6294):aac4354. doi: 10.1126/science.aac4354. Review.

PMID:
27365453
32.

Compositional diversity of rehabilitated tropical lands supports multiple ecosystem services and buffers uncertainties.

Knoke T, Paul C, Hildebrandt P, Calvas B, Castro LM, Härtl F, Döllerer M, Hamer U, Windhorst D, Wiersma YF, Curatola Fernández GF, Obermeier WA, Adams J, Breuer L, Mosandl R, Beck E, Weber M, Stimm B, Haber W, Fürst C, Bendix J.

Nat Commun. 2016 Jun 13;7:11877. doi: 10.1038/ncomms11877.

33.

The formation, function and regulation of amyloids: insights from structural biology.

Landreh M, Sawaya MR, Hipp MS, Eisenberg DS, Wüthrich K, Hartl FU.

J Intern Med. 2016 Aug;280(2):164-76. doi: 10.1111/joim.12500. Epub 2016 May 30. Review.

PMID:
27237473
34.

Correction: Nck Binds to the T Cell Antigen Receptor Using Its SH3.1 and SH2 Domains in a Cooperative Manner, Promoting TCR Functioning.

Paensuwan P, Hartl FA, Yousefi OS, Ngoenkam J, Wipa P, Beck-Garcia E, Dopfer EP, Khamsri B, Sanguansermsri D, Minguet S, Schamel WW, Pongcharoen S.

J Immunol. 2016 Jun 1;196(11):4833. doi: 10.4049/jimmunol.1600551. No abstract available.

35.

A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation.

Swamy M, Beck-Garcia K, Beck-Garcia E, Hartl FA, Morath A, Yousefi OS, Dopfer EP, Molnár E, Schulze AK, Blanco R, Borroto A, Martín-Blanco N, Alarcon B, Höfer T, Minguet S, Schamel WW.

Immunity. 2016 May 17;44(5):1091-101. doi: 10.1016/j.immuni.2016.04.011.

36.

Cellular Homeostasis and Aging.

Hartl FU.

Annu Rev Biochem. 2016 Jun 2;85:1-4. doi: 10.1146/annurev-biochem-011116-110806. Epub 2016 Apr 6. Review.

PMID:
27050288
37.

Notable differences between oxidized diruthenium complexes bridged by four isomeric diethynyl benzodithiophene ligands.

Ou YP, Zhang J, Zhang F, Kuang D, Hartl F, Rao L, Liu SH.

Dalton Trans. 2016 Apr 21;45(15):6503-16. doi: 10.1039/c6dt00109b.

PMID:
26953807
38.

Failure of RQC machinery causes protein aggregation and proteotoxic stress.

Choe YJ, Park SH, Hassemer T, Körner R, Vincenz-Donnelly L, Hayer-Hartl M, Hartl FU.

Nature. 2016 Mar 10;531(7593):191-5. doi: 10.1038/nature16973. Epub 2016 Feb 29.

PMID:
26934223
39.

Effects of Electrode-Molecule Binding and Junction Geometry on the Single-Molecule Conductance of bis-2,2':6',2″-Terpyridine-based Complexes.

Davidson R, Al-Owaedi OA, Milan DC, Zeng Q, Tory J, Hartl F, Higgins SJ, Nichols RJ, Lambert CJ, Low PJ.

Inorg Chem. 2016 Mar 21;55(6):2691-700. doi: 10.1021/acs.inorgchem.5b02094. Epub 2016 Feb 24.

PMID:
26909823
40.

Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells.

Schönle A, Hartl FA, Mentzel J, Nöltner T, Rauch KS, Prestipino A, Wohlfeil SA, Apostolova P, Hechinger AK, Melchinger W, Fehrenbach K, Guadamillas MC, Follo M, Prinz G, Ruess AK, Pfeifer D, del Pozo MA, Schmitt-Graeff A, Duyster J, Hippen KI, Blazar BR, Schachtrup K, Minguet S, Zeiser R.

Blood. 2016 Apr 14;127(15):1930-9. doi: 10.1182/blood-2015-09-672428. Epub 2016 Feb 2.

41.

Structure of human heat-shock transcription factor 1 in complex with DNA.

Neudegger T, Verghese J, Hayer-Hartl M, Hartl FU, Bracher A.

Nat Struct Mol Biol. 2016 Feb;23(2):140-6. doi: 10.1038/nsmb.3149. Epub 2016 Jan 4.

PMID:
26727489
42.

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.

Woerner AC, Frottin F, Hornburg D, Feng LR, Meissner F, Patra M, Tatzelt J, Mann M, Winklhofer KF, Hartl FU, Hipp MS.

Science. 2016 Jan 8;351(6269):173-6. doi: 10.1126/science.aad2033. Epub 2015 Dec 3.

43.

Asymmetric oxidation of vinyl- and ethynyl terthiophene ligands in triruthenium complexes.

Zhang J, Sun CF, Zhang MX, Hartl F, Yin J, Yu GA, Rao L, Liu SH.

Dalton Trans. 2016 Jan 14;45(2):768-82. doi: 10.1039/c5dt04083c.

PMID:
26632006
44.

Efficient access to conjugated 4,4'-bipyridinium oligomers using the Zincke reaction: synthesis, spectroscopic and electrochemical properties.

Chen L, Willcock H, Wedge CJ, Hartl F, Colquhoun HM, Greenland BW.

Org Biomol Chem. 2016 Jan 21;14(3):980-8. doi: 10.1039/c5ob02211h. Epub 2015 Dec 2.

PMID:
26626110
45.

Nck Binds to the T Cell Antigen Receptor Using Its SH3.1 and SH2 Domains in a Cooperative Manner, Promoting TCR Functioning.

Paensuwan P, Hartl FA, Yousefi OS, Ngoenkam J, Wipa P, Beck-Garcia E, Dopfer EP, Khamsri B, Sanguansermsri D, Minguet S, Schamel WW, Pongcharoen S.

J Immunol. 2016 Jan 1;196(1):448-58. doi: 10.4049/jimmunol.1500958. Epub 2015 Nov 20. Erratum in: J Immunol. 2016 Jun 1;196(11):4833.

46.

Electrochemical Single-Molecule Transistors with Optimized Gate Coupling.

Osorio HM, Catarelli S, Cea P, Gluyas JB, Hartl F, Higgins SJ, Leary E, Low PJ, Martín S, Nichols RJ, Tory J, Ulstrup J, Vezzoli A, Milan DC, Zeng Q.

J Am Chem Soc. 2015 Nov 18;137(45):14319-28. doi: 10.1021/jacs.5b08431. Epub 2015 Nov 4.

PMID:
26488257
47.

The GroEL-GroES Chaperonin Machine: A Nano-Cage for Protein Folding.

Hayer-Hartl M, Bracher A, Hartl FU.

Trends Biochem Sci. 2016 Jan;41(1):62-76. doi: 10.1016/j.tibs.2015.07.009. Epub 2015 Sep 25. Review.

PMID:
26422689
48.

Structural Analysis of the Rubisco-Assembly Chaperone RbcX-II from Chlamydomonas reinhardtii.

Bracher A, Hauser T, Liu C, Hartl FU, Hayer-Hartl M.

PLoS One. 2015 Aug 25;10(8):e0135448. doi: 10.1371/journal.pone.0135448. eCollection 2015.

49.

Elucidating the Structure of Chiral Molecules by using Amplified Vibrational Circular Dichroism: From Theory to Experimental Realization.

Domingos SR, Hartl F, Buma WJ, Woutersen S.

Chemphyschem. 2015 Nov 16;16(16):3363-73. doi: 10.1002/cphc.201500551. Epub 2015 Sep 9.

PMID:
26289778
50.

Structure and mechanism of the Rubisco-assembly chaperone Raf1.

Hauser T, Bhat JY, Miličić G, Wendler P, Hartl FU, Bracher A, Hayer-Hartl M.

Nat Struct Mol Biol. 2015 Sep;22(9):720-8. doi: 10.1038/nsmb.3062. Epub 2015 Aug 3.

PMID:
26237510

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