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Items: 21

1.

Neutralization of rhesus cytomegalovirus IL-10 reduces horizontal transmission and alters long-term immunity.

Deere JD, Chang WLW, Villalobos A, Schmidt KA, Deshpande A, Castillo LD, Fike J, Walter MR, Barry PA, Hartigan-O'Connor DJ.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13036-13041. doi: 10.1073/pnas.1903317116. Epub 2019 Jun 12.

PMID:
31189602
2.

Disruption of latent HIV in vivo during the clearance of actinic keratosis by ingenol mebutate.

Jiang G, Maverakis E, Cheng MY, Elsheikh MM, Deleage C, Méndez-Lagares G, Shimoda M, Yukl SA, Hartigan-O'Connor DJ, Thompson GR 3rd, Estes JD, Wong JK, Dandekar S.

JCI Insight. 2019 Apr 4;4(7). pii: 126027. doi: 10.1172/jci.insight.126027. eCollection 2019 Apr 4.

3.

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.

Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM.

Nat Med. 2019 Jan;25(1):141-151. doi: 10.1038/s41591-018-0221-5. Epub 2018 Nov 12.

4.

Idiopathic Colitis in Rhesus Macaques Is Associated With Dysbiosis, Abundant Enterochromaffin Cells and Altered T-Cell Cytokine Expression.

Laing ST, Merriam D, Shock BC, Mills S, Spinner A, Reader R, Hartigan-O'Connor DJ.

Vet Pathol. 2018 Sep;55(5):741-752. doi: 10.1177/0300985818780449. Epub 2018 Jun 21.

PMID:
29929446
5.

Subclinical Cytomegalovirus Infection Is Associated with Altered Host Immunity, Gut Microbiota, and Vaccine Responses.

Santos Rocha C, Hirao LA, Weber MG, Méndez-Lagares G, Chang WLW, Jiang G, Deere JD, Sparger EE, Roberts J, Barry PA, Hartigan-O'Connor DJ, Dandekar S.

J Virol. 2018 Jun 13;92(13). pii: e00167-18. doi: 10.1128/JVI.00167-18. Print 2018 Jul 1.

6.

HIV latency is reversed by ACSS2-driven histone crotonylation.

Jiang G, Nguyen D, Archin NM, Yukl SA, Méndez-Lagares G, Tang Y, Elsheikh MM, Thompson GR 3rd, Hartigan-O'Connor DJ, Margolis DM, Wong JK, Dandekar S.

J Clin Invest. 2018 Mar 1;128(3):1190-1198. doi: 10.1172/JCI98071. Epub 2018 Feb 19.

7.

Memory T Cell Proliferation before Hepatitis C Virus Therapy Predicts Antiviral Immune Responses and Treatment Success.

Méndez-Lagares G, Lu D, Chen C, Terrault N, Segal MR, Khalili M, Monto A, Shen H, Manos MM, Lanier LL, Ryan JC, McCune JM, Hartigan-O'Connor DJ.

J Immunol. 2018 Feb 1;200(3):1124-1132. doi: 10.4049/jimmunol.1701364. Epub 2017 Dec 20.

8.

IL-21 Therapy Controls Immune Activation and Maintains Antiviral CD8+ T Cell Responses in Acute Simian Immunodeficiency Virus Infection.

Méndez-Lagares G, Lu D, Merriam D, Baker CA, Villinger F, Van Rompay KKA, McCune JM, Hartigan-O'Connor DJ.

AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S81-S92. doi: 10.1089/aid.2017.0160.

9.

Depletion of Gut-Resident CCR5+ Cells for HIV Cure Strategies.

Merriam D, Chen C, Méndez-Lagares G, Rogers KA, Michaels AJ, Yan J, Casaz P, Reimann KA, Villinger F, Hartigan-O'Connor DJ.

AIDS Res Hum Retroviruses. 2017 Nov;33(S1):S70-S80. doi: 10.1089/aid.2017.0159.

10.

Exposure to SIV in utero results in reduced viral loads and altered responsiveness to postnatal challenge.

Baker CA, Swainson L, Lin DL, Wong S, Hartigan-O'Connor DJ, Lifson JD, Tarantal AF, McCune JM.

Sci Transl Med. 2015 Aug 12;7(300):300ra125. doi: 10.1126/scitranslmed.aac5547.

11.

Persistent effects of early infant diet and associated microbiota on the juvenile immune system.

Narayan NR, Méndez-Lagares G, Ardeshir A, Lu D, Van Rompay KK, Hartigan-O'Connor DJ.

Gut Microbes. 2015 Jul 4;6(4):284-9. doi: 10.1080/19490976.2015.1067743.

12.

Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems.

Ardeshir A, Narayan NR, Méndez-Lagares G, Lu D, Rauch M, Huang Y, Van Rompay KK, Lynch SV, Hartigan-O'Connor DJ.

Sci Transl Med. 2014 Sep 3;6(252):252ra120. doi: 10.1126/scitranslmed.3008791.

13.

Monocyte activation by interferon α is associated with failure to achieve a sustained virologic response after treatment for hepatitis C virus infection.

Hartigan-O'Connor DJ, Lin D, Ryan JC, Shvachko VA, Cozen ML, Segal MR, Terrault NA, Lanier LL, Manos MM, McCune JM.

J Infect Dis. 2014 May 15;209(10):1602-12. doi: 10.1093/infdis/jit801. Epub 2013 Dec 10.

14.

IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia.

Miller CN, Hartigan-O'Connor DJ, Lee MS, Laidlaw G, Cornelissen IP, Matloubian M, Coughlin SR, McDonald DM, McCune JM.

Int Immunol. 2013 Aug;25(8):471-83. doi: 10.1093/intimm/dxt012. Epub 2013 May 8.

15.

SIV replication in the infected rhesus macaque is limited by the size of the preexisting TH17 cell compartment.

Hartigan-O'Connor DJ, Abel K, Van Rompay KK, Kanwar B, McCune JM.

Sci Transl Med. 2012 May 30;4(136):136ra69. doi: 10.1126/scitranslmed.3003941.

16.

Th17 cells and regulatory T cells in elite control over HIV and SIV.

Hartigan-O'Connor DJ, Hirao LA, McCune JM, Dandekar S.

Curr Opin HIV AIDS. 2011 May;6(3):221-7. doi: 10.1097/COH.0b013e32834577b3. Review.

17.

The human fetal immune response to hepatitis C virus exposure in utero.

Babik JM, Cohan D, Monto A, Hartigan-O'Connor DJ, McCune JM.

J Infect Dis. 2011 Jan 15;203(2):196-206. doi: 10.1093/infdis/jiq044.

18.

Development of cytomegalovirus (CMV) immune recovery uveitis is associated with Th17 cell depletion and poor systemic CMV-specific T cell responses.

Hartigan-O'Connor DJ, Jacobson MA, Tan QX, Sinclair E; Studies of Ocular Complications of AIDS Research Group.

Clin Infect Dis. 2011 Feb 1;52(3):409-17. doi: 10.1093/cid/ciq112. Epub 2010 Dec 28.

19.

Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression.

Hartigan-O'Connor DJ, Abel K, McCune JM.

J Exp Med. 2007 Oct 29;204(11):2679-92. Epub 2007 Oct 22.

20.

Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells.

Hartigan-O'Connor DJ, Poon C, Sinclair E, McCune JM.

J Immunol Methods. 2007 Jan 30;319(1-2):41-52. Epub 2006 Nov 3.

PMID:
17173927
21.

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells.

Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS.

Development. 1998 Jun;125(12):2213-21.

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