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Items: 1 to 50 of 82

1.

Plasma Cell Alloantigen 1 and IL-10 Secretion Define Two Distinct Peritoneal B1a B Cell Subsets With Opposite Functions, PC1high Cells Being Protective and PC1low Cells Harmful for the Growing Fetus.

Schumacher A, Ehrentraut S, Scharm M, Wang H, Hartig R, Morse HC 3rd, Zenclussen AC.

Front Immunol. 2018 May 15;9:1045. doi: 10.3389/fimmu.2018.01045. eCollection 2018.

2.

HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience.

Raza SA, Albrecht A, Çalışkan G, Müller B, Demiray YE, Ludewig S, Meis S, Faber N, Hartig R, Schraven B, Lessmann V, Schwegler H, Stork O.

Nat Commun. 2017 Aug 4;8(1):189. doi: 10.1038/s41467-017-00205-3.

3.

Chk1 Promotes DNA Damage Response Bypass following Oxidative Stress in a Model of Hydrogen Peroxide-Associated Ulcerative Colitis through JNK Inactivation and Chromatin Binding.

Reissig K, Silver A, Hartig R, Schinlauer A, Walluscheck D, Guenther T, Siedentopf S, Ross J, Vo DK, Roessner A, Poehlmann-Nitsche A.

Oxid Med Cell Longev. 2017;2017:9303158. doi: 10.1155/2017/9303158. Epub 2017 Jun 7.

4.

Alterations in the Peripheral Immune System in Dementia.

Busse M, Michler E, von Hoff F, Dobrowolny H, Hartig R, Frodl T, Busse S.

J Alzheimers Dis. 2017;58(4):1303-1313. doi: 10.3233/JAD-161304.

PMID:
28582858
5.

Increased quinolinic acid in peripheral mononuclear cells in Alzheimer's dementia.

Busse M, Hettler V, Fischer V, Mawrin C, Hartig R, Dobrowolny H, Bogerts B, Frodl T, Busse S.

Eur Arch Psychiatry Clin Neurosci. 2018 Aug;268(5):493-500. doi: 10.1007/s00406-017-0785-y. Epub 2017 Apr 6.

PMID:
28386767
6.

De novo phosphorylation and conformational opening of the tyrosine kinase Lck act in concert to initiate T cell receptor signaling.

Philipsen L, Reddycherla AV, Hartig R, Gumz J, Kästle M, Kritikos A, Poltorak MP, Prokazov Y, Turbin E, Weber A, Zuschratter W, Schraven B, Simeoni L, Müller AJ.

Sci Signal. 2017 Jan 17;10(462). pii: eaaf4736. doi: 10.1126/scisignal.aaf4736.

PMID:
28096507
7.

T Cells of Infants Are Mature, but Hyporeactive Due to Limited Ca2+ Influx.

Schmiedeberg K, Krause H, Röhl FW, Hartig R, Jorch G, Brunner-Weinzierl MC.

PLoS One. 2016 Nov 28;11(11):e0166633. doi: 10.1371/journal.pone.0166633. eCollection 2016.

8.

Verapamil inhibits tumor progression of chemotherapy-resistant pancreatic cancer side population cells.

Zhao L, Zhao Y, Schwarz B, Mysliwietz J, Hartig R, Camaj P, Bao Q, Jauch KW, Guba M, Ellwart JW, Nelson PJ, Bruns CJ.

Int J Oncol. 2016 Jul;49(1):99-110. doi: 10.3892/ijo.2016.3512. Epub 2016 May 10.

9.

Physiological Concentration of Exogenous Lactate Reduces Antimycin A Triggered Oxidative Stress in Intestinal Epithelial Cell Line IPEC-1 and IPEC-J2 In Vitro.

Kahlert S, Junnikkala S, Renner L, Hynönen U, Hartig R, Nossol C, Barta-Böszörményi A, Dänicke S, Souffrant WB, Palva A, Rothkötter HJ, Kluess J.

PLoS One. 2016 Apr 7;11(4):e0153135. doi: 10.1371/journal.pone.0153135. eCollection 2016.

10.

DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T Magnetic Resonance Imaging.

Fatahi M, Reddig A, Vijayalaxmi, Friebe B, Hartig R, Prihoda TJ, Ricke J, Roggenbuck D, Reinhold D, Speck O.

Neuroimage. 2016 Jun;133:288-293. doi: 10.1016/j.neuroimage.2016.03.023. Epub 2016 Mar 16.

PMID:
26994830
11.

Expression of HLA-DR, CD80, and CD86 in Healthy Aging and Alzheimer's Disease.

Busse S, Steiner J, Alter J, Dobrowolny H, Mawrin C, Bogerts B, Hartig R, Busse M.

J Alzheimers Dis. 2015;47(1):177-84. doi: 10.3233/JAD-150217.

PMID:
26402766
12.

Insulin and insulin-like growth factor-1 can modulate the phosphoinositide-3-kinase/Akt/FoxO1 pathway in SZ95 sebocytes in vitro.

Mirdamadi Y, Thielitz A, Wiede A, Goihl A, Papakonstantinou E, Hartig R, Zouboulis CC, Reinhold D, Simeoni L, Bommhardt U, Quist S, Gollnick H.

Mol Cell Endocrinol. 2015 Nov 5;415:32-44. doi: 10.1016/j.mce.2015.08.001. Epub 2015 Aug 6.

PMID:
26257240
13.

Analysis of DNA Double-Strand Breaks and Cytotoxicity after 7 Tesla Magnetic Resonance Imaging of Isolated Human Lymphocytes.

Reddig A, Fatahi M, Friebe B, Guttek K, Hartig R, Godenschweger F, Roggenbuck D, Ricke J, Reinhold D, Speck O.

PLoS One. 2015 Jul 15;10(7):e0132702. doi: 10.1371/journal.pone.0132702. eCollection 2015.

14.

VGF expression by T lymphocytes in patients with Alzheimer's disease.

Busse S, Steiner J, Glorius S, Dobrowolny H, Greiner-Bohl S, Mawrin C, Bommhardt U, Hartig R, Bogerts B, Busse M.

Oncotarget. 2015 Jun 20;6(17):14843-51.

15.

Assessment of modulated cytostatic drug resistance by automated γH2AX analysis.

Reddig A, Lorenz S, Hiemann R, Guttek K, Hartig R, Heiserich L, Eberle C, Peters V, Schierack P, Sack U, Roggenbuck D, Reinhold D.

Cytometry A. 2015 Aug;87(8):724-32. doi: 10.1002/cyto.a.22667. Epub 2015 Apr 2.

16.

Dysregulation of apoptotic signaling pathways by interaction of RPLP0 and cathepsin X/Z in gastric cancer.

Teller A, Jechorek D, Hartig R, Adolf D, Reißig K, Roessner A, Franke S.

Pathol Res Pract. 2015 Jan;211(1):62-70. doi: 10.1016/j.prp.2014.09.005. Epub 2014 Sep 28.

PMID:
25433997
17.

Age-related increase of VGF-expression in T lymphocytes.

Busse S, Steiner J, Micheel J, Dobrowolny H, Mawrin C, Krause TJ, Adamaszek M, Bogerts B, Bommhardt U, Hartig R, Busse M.

Aging (Albany NY). 2014 Jun;6(6):440-53.

18.

Differential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells.

Nass N, Brömme HJ, Hartig R, Korkmaz S, Sel S, Hirche F, Ward A, Simm A, Wiemann S, Lykkesfeldt AE, Roessner A, Kalinski T.

PLoS One. 2014 Jul 1;9(7):e101473. doi: 10.1371/journal.pone.0101473. eCollection 2014. Erratum in: PLoS One. 2014;9(7):e104322.

19.

Induction of Candida albicans biofilm formation on silver-coated vascular grafts.

Tammer I, Reuner J, Hartig R, Geginat G.

J Antimicrob Chemother. 2014 May;69(5):1282-5. doi: 10.1093/jac/dkt521. Epub 2014 Jan 20.

PMID:
24448486
20.

Repeated H2 O2 exposure drives cell cycle progression in an in vitro model of ulcerative colitis.

Poehlmann A, Reissig K, Schönfeld P, Walluscheck D, Schinlauer A, Hartig R, Lessel W, Guenther T, Silver A, Roessner A.

J Cell Mol Med. 2013 Dec;17(12):1619-31. doi: 10.1111/jcmm.12150. Epub 2013 Oct 9.

21.

Cutting edge: IL-10-producing regulatory B cells in early human pregnancy.

Rolle L, Memarzadeh Tehran M, Morell-García A, Raeva Y, Schumacher A, Hartig R, Costa SD, Jensen F, Zenclussen AC.

Am J Reprod Immunol. 2013 Dec;70(6):448-53. doi: 10.1111/aji.12157. Epub 2013 Oct 10.

PMID:
24118333
22.

Wide-field fluorescence lifetime imaging with multi-anode detectors.

Hartig R, Prokazov Y, Turbin E, Zuschratter W.

Methods Mol Biol. 2014;1076:457-80. doi: 10.1007/978-1-62703-649-8_20.

PMID:
24108639
23.

Fully automated analysis of chemically induced γH2AX foci in human peripheral blood mononuclear cells by indirect immunofluorescence.

Willitzki A, Lorenz S, Hiemann R, Guttek K, Goihl A, Hartig R, Conrad K, Feist E, Sack U, Schierack P, Heiserich L, Eberle C, Peters V, Roggenbuck D, Reinhold D.

Cytometry A. 2013 Nov;83(11):1017-26. doi: 10.1002/cyto.a.22350. Epub 2013 Sep 5.

24.

Deoxynivalenol affects the composition of the basement membrane proteins and influences en route the migration of CD16(+) cells into the intestinal epithelium.

Nossol C, Diesing AK, Kahlert S, Kersten S, Kluess J, Ponsuksili S, Hartig R, Wimmers K, Dänicke S, Rothkötter HJ.

Mycotoxin Res. 2013 Nov;29(4):245-54. doi: 10.1007/s12550-013-0177-8. Epub 2013 Aug 16.

25.

ATF2 knockdown reinforces oxidative stress-induced apoptosis in TE7 cancer cells.

Walluscheck D, Poehlmann A, Hartig R, Lendeckel U, Schönfeld P, Hotz-Wagenblatt A, Reissig K, Bajbouj K, Roessner A, Schneider-Stock R.

J Cell Mol Med. 2013 Aug;17(8):976-88. doi: 10.1111/jcmm.12071. Epub 2013 Jun 25.

26.

Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis.

Poehlmann A, Reissig K, Just A, Walluscheck D, Hartig R, Schinlauer A, Lessel W, Guenther T, Silver A, Steinberg P, Roessner A.

J Cell Mol Med. 2013 Jul;17(7):901-13. doi: 10.1111/jcmm.12079. Epub 2013 Jun 7.

27.

T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.

Stirnweiss A, Hartig R, Gieseler S, Lindquist JA, Reichardt P, Philipsen L, Simeoni L, Poltorak M, Merten C, Zuschratter W, Prokazov Y, Paster W, Stockinger H, Harder T, Gunzer M, Schraven B.

Sci Signal. 2013 Feb 19;6(263):ra13. doi: 10.1126/scisignal.2003607.

PMID:
23423439
28.

Sunitinib targets PDGF-receptor and Flt3 and reduces survival and migration of human meningioma cells.

Andrae N, Kirches E, Hartig R, Haase D, Keilhoff G, Kalinski T, Mawrin C.

Eur J Cancer. 2012 Aug;48(12):1831-41. doi: 10.1016/j.ejca.2012.01.032. Epub 2012 Mar 3.

PMID:
22391574
29.

Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases.

Linka RM, Risse SL, Bienemann K, Werner M, Linka Y, Krux F, Synaeve C, Deenen R, Ginzel S, Dvorsky R, Gombert M, Halenius A, Hartig R, Helminen M, Fischer A, Stepensky P, Vettenranta K, Köhrer K, Ahmadian MR, Laws HJ, Fleckenstein B, Jumaa H, Latour S, Schraven B, Borkhardt A.

Leukemia. 2012 May;26(5):963-71. doi: 10.1038/leu.2011.371. Epub 2012 Jan 6.

PMID:
22289921
30.

P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.

Bajbouj K, Mawrin C, Hartig R, Schulze-Luehrmann J, Wilisch-Neumann A, Roessner A, Schneider-Stock R.

J Neurooncol. 2012 May;107(3):503-16. doi: 10.1007/s11060-011-0791-2. Epub 2012 Jan 20.

PMID:
22270849
31.

Air-liquid interface cultures enhance the oxygen supply and trigger the structural and functional differentiation of intestinal porcine epithelial cells (IPEC).

Nossol C, Diesing AK, Walk N, Faber-Zuschratter H, Hartig R, Post A, Kluess J, Rothkötter HJ, Kahlert S.

Histochem Cell Biol. 2011 Jul;136(1):103-15. doi: 10.1007/s00418-011-0826-y. Epub 2011 Jun 17.

32.

Serine phosphorylation of cortactin controls focal adhesion kinase activity and cell scattering induced by Helicobacter pylori.

Tegtmeyer N, Wittelsberger R, Hartig R, Wessler S, Martinez-Quiles N, Backert S.

Cell Host Microbe. 2011 Jun 16;9(6):520-31. doi: 10.1016/j.chom.2011.05.007.

33.

Wide-Field Multi-Parameter FLIM: long-term minimal invasive observation of proteins in living cells.

Vitali M, Picazo F, Prokazov Y, Duci A, Turbin E, Götze C, Llopis J, Hartig R, Visser AJ, Zuschratter W.

PLoS One. 2011 Feb 2;6(2):e15820. doi: 10.1371/journal.pone.0015820.

34.

Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G₂ checkpoint arrest.

Poehlmann A, Habold C, Walluscheck D, Reissig K, Bajbouj K, Ullrich O, Hartig R, Gali-Muhtasib H, Diestel A, Roessner A, Schneider-Stock R.

J Cell Mol Med. 2011 Jul;15(7):1528-41. doi: 10.1111/j.1582-4934.2010.01143.x.

35.

A small fibronectin-mimicking protein from bacteria induces cell spreading and focal adhesion formation.

Tegtmeyer N, Hartig R, Delahay RM, Rohde M, Brandt S, Conradi J, Takahashi S, Smolka AJ, Sewald N, Backert S.

J Biol Chem. 2010 Jul 23;285(30):23515-26. doi: 10.1074/jbc.M109.096214. Epub 2010 May 27.

36.

Primary porcine CD11R1+ antigen-presenting cells isolated from small intestinal mucosa mature but lose their T cell stimulatory function in response to cholera toxin treatment.

Bimczok D, Verdonck F, Hartig R, Cox E, Rothkötter HJ.

Vet Immunol Immunopathol. 2010 Apr 15;134(3-4):239-48. doi: 10.1016/j.vetimm.2009.10.022. Epub 2009 Oct 29.

PMID:
19926143
37.

RETRACTED: Identification of phosphorylated p38 as a novel DAPK-interacting partner during TNFalpha-induced apoptosis in colorectal tumor cells.

Bajbouj K, Poehlmann A, Kuester D, Drewes T, Haase K, Hartig R, Teller A, Kliche S, Walluscheck D, Ivanovska J, Chakilam S, Ulitzsch A, Bommhardt U, Leverkus M, Roessner A, Schneider-Stock R.

Am J Pathol. 2009 Aug;175(2):557-70. doi: 10.2353/ajpath.2009.080853. Epub 2009 Jul 23. Retraction in: Am J Pathol. 2017 Jan;187(1):225.

38.

Mechanisms of opioid-mediated inhibition of human T cell receptor signaling.

Börner C, Warnick B, Smida M, Hartig R, Lindquist JA, Schraven B, Höllt V, Kraus J.

J Immunol. 2009 Jul 15;183(2):882-9. doi: 10.4049/jimmunol.0802763. Epub 2009 Jun 26.

39.

Helicobacter pylori activates protein kinase C delta to control Raf in MAP kinase signalling: role in AGS epithelial cell scattering and elongation.

Brandt S, Wessler S, Hartig R, Backert S.

Cell Motil Cytoskeleton. 2009 Oct;66(10):874-92. doi: 10.1002/cm.20373.

PMID:
19437514
40.

Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by the Helicobacter pylori CagA protein: antagonistic effects of the vacuolating cytotoxin VacA.

Tegtmeyer N, Zabler D, Schmidt D, Hartig R, Brandt S, Backert S.

Cell Microbiol. 2009 Mar;11(3):488-505. doi: 10.1111/j.1462-5822.2008.01269.x. Epub 2008 Nov 25.

PMID:
19046339
41.
42.

Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis.

Habold C, Poehlmann A, Bajbouj K, Hartig R, Korkmaz KS, Roessner A, Schneider-Stock R.

J Cell Mol Med. 2008 Apr;12(2):607-21. doi: 10.1111/j.1582-4934.2007.00136.x. Erratum in: J Cell Mol Med. 2008 Aug;12(4):1421.

43.

Signaling signatures and functional properties of anti-human CD28 superagonistic antibodies.

Waibler Z, Sender LY, Merten C, Hartig R, Kliche S, Gunzer M, Reichardt P, Kalinke U, Schraven B.

PLoS One. 2008 Mar 5;3(3):e1708. doi: 10.1371/journal.pone.0001708.

44.

A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration.

Posevitz-Fejfár A, Smída M, Kliche S, Hartig R, Schraven B, Lindquist JA.

Eur J Immunol. 2008 Jan;38(1):250-9.

45.

Helicobacter exploits integrin for type IV secretion and kinase activation.

Kwok T, Zabler D, Urman S, Rohde M, Hartig R, Wessler S, Misselwitz R, Berger J, Sewald N, König W, Backert S.

Nature. 2007 Oct 18;449(7164):862-6.

PMID:
17943123
46.
47.

Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni.

Krause-Gruszczynska M, Rohde M, Hartig R, Genth H, Schmidt G, Keo T, König W, Miller WG, Konkel ME, Backert S.

Cell Microbiol. 2007 Oct;9(10):2431-44. Epub 2007 May 23.

PMID:
17521326
48.

Use of a novel coinfection system reveals a role for Rac1, H-Ras, and CrkII phosphorylation in Helicobacter pylori-induced host cell actin cytoskeletal rearrangements.

Brandt S, Shafikhani S, Balachandran P, Jin S, Hartig R, König W, Engel J, Backert S.

FEMS Immunol Med Microbiol. 2007 Jul;50(2):190-205. Epub 2007 Apr 11.

49.

Activation of Abl by Helicobacter pylori: a novel kinase for CagA and crucial mediator of host cell scattering.

Tammer I, Brandt S, Hartig R, König W, Backert S.

Gastroenterology. 2007 Apr;132(4):1309-19. Epub 2007 Feb 1.

PMID:
17408661
50.

Early involvement of death-associated protein kinase promoter hypermethylation in the carcinogenesis of Barrett's esophageal adenocarcinoma and its association with clinical progression.

Kuester D, Dar AA, Moskaluk CC, Krueger S, Meyer F, Hartig R, Stolte M, Malfertheiner P, Lippert H, Roessner A, El-Rifai W, Schneider-Stock R.

Neoplasia. 2007 Mar;9(3):236-45.

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