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Items: 14


Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer.

Parkes EE, Walker SM, Taggart LE, McCabe N, Knight LA, Wilkinson R, McCloskey KD, Buckley NE, Savage KI, Salto-Tellez M, McQuaid S, Harte MT, Mullan PB, Harkin DP, Kennedy RD.

J Natl Cancer Inst. 2016 Oct 5;109(1). doi: 10.1093/jnci/djw199. Print 2017 Jan.


NF-κB is a critical mediator of BRCA1-induced chemoresistance.

Harte MT, Gorski JJ, Savage KI, Purcell JW, Barros EM, Burn PM, McFarlane C, Mullan PB, Kennedy RD, Perkins ND, Harkin DP.

Oncogene. 2014 Feb 6;33(6):713-723. doi: 10.1038/onc.2013.10. Epub 2013 Feb 25.


BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.

Harte MT, O'Brien GJ, Ryan NM, Gorski JJ, Savage KI, Crawford NT, Mullan PB, Harkin DP.

Cancer Res. 2010 Mar 15;70(6):2538-47. doi: 10.1158/0008-5472.CAN-09-2089. Epub 2010 Mar 9.


The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense.

Harte MT, Haga IR, Maloney G, Gray P, Reading PC, Bartlett NW, Smith GL, Bowie A, O'Neill LA.

J Exp Med. 2003 Feb 3;197(3):343-51.


Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA.

Nature. 2001 Sep 6;413(6851):78-83.


Identification of two focal adhesion targeting sequences in the adapter molecule p130(Cas).

Harte MT, Macklem M, Weidow CL, Parsons JT, Bouton AH.

Biochim Biophys Acta. 2000 Dec 11;1499(1-2):34-48.


Regulation of c-SRC activity and function by the adapter protein CAS.

Burnham MR, Bruce-Staskal PJ, Harte MT, Weidow CL, Ma A, Weed SA, Bouton AH.

Mol Cell Biol. 2000 Aug;20(16):5865-78.


Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region.

Adrain C, Slee EA, Harte MT, Martin SJ.

J Biol Chem. 1999 Jul 23;274(30):20855-60.


Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner.

Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA, Newmeyer DD, Wang HG, Reed JC, Nicholson DW, Alnemri ES, Green DR, Martin SJ.

J Cell Biol. 1999 Jan 25;144(2):281-92.


p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase.

Harte MT, Hildebrand JD, Burnham MR, Bouton AH, Parsons JT.

J Biol Chem. 1996 Jun 7;271(23):13649-55.


The identification of p130cas-binding proteins and their role in cellular transformation.

Burnham MR, Harte MT, Richardson A, Parsons JT, Bouton AH.

Oncogene. 1996 Jun 6;12(11):2467-72.


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