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Items: 1 to 50 of 173

1.

ALLELE-SPECIFIC SIRNA CORRECTS ABERRANT CELLULAR PHENOTYPE IN KERATITIS-ICHTHYOSIS-DEAFNESS SYNDROME KERATINOCYTES.

Lee MY, Wang HZ, White TW, Brooks T, Pittman A, Halai H, Petrova A, Xu D, Hart SL, Kinsler VA, Di WL.

J Invest Dermatol. 2019 Nov 6. pii: S0022-202X(19)33381-0. doi: 10.1016/j.jid.2019.09.022. [Epub ahead of print]

PMID:
31705875
2.

A Nanosensor Toolbox for Rapid, Label-Free Measurement of Airway Surface Liquid and Epithelial Cell Function.

Ivanova R, Benton DCH, Munye MM, Rangseesorranan S, Hart SL, Moss GWJ.

ACS Appl Mater Interfaces. 2019 Mar 6;11(9):8731-8739. doi: 10.1021/acsami.8b14122. Epub 2019 Feb 25.

PMID:
30648848
3.

The discovery and enhanced properties of trichain lipids in lipopolyplex gene delivery systems.

Mohammadi A, Kudsiova L, Mustapa MFM, Campbell F, Vlaho D, Welser K, Story H, Tagalakis AD, Hart SL, Barlow DJ, Tabor AB, Lawrence MJ, Hailes HC.

Org Biomol Chem. 2019 Jan 23;17(4):945-957. doi: 10.1039/c8ob02374c.

4.

Development of Targeted siRNA Nanocomplexes to Prevent Fibrosis in Experimental Glaucoma Filtration Surgery.

Fernando O, Tagalakis AD, Awwad S, Brocchini S, Khaw PT, Hart SL, Yu-Wai-Man C.

Mol Ther. 2018 Dec 5;26(12):2812-2822. doi: 10.1016/j.ymthe.2018.09.004. Epub 2018 Sep 11.

5.

Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung.

Tagalakis AD, Munye MM, Ivanova R, Chen H, Smith CM, Aldossary AM, Rosa LZ, Moulding D, Barnes JL, Kafetzis KN, Jones SA, Baines DL, Moss GWJ, O'Callaghan C, McAnulty RJ, Hart SL.

Thorax. 2018 Sep;73(9):847-856. doi: 10.1136/thoraxjnl-2017-210670. Epub 2018 May 10.

6.

Genetic therapies for cystic fibrosis lung disease.

Hart SL, Harrison PT.

Curr Opin Pharmacol. 2017 Jun;34:119-124. doi: 10.1016/j.coph.2017.10.006. Epub 2017 Nov 5. Review.

PMID:
29107808
7.

Genotype-Phenotype Associations of IL6 and PRG4 With Conjunctival Fibrosis After Glaucoma Surgery.

Yu-Wai-Man C, Tagalakis AD, Meng J, Bouremel Y, Lee RMH, Virasami A, Hart SL, Khaw PT.

JAMA Ophthalmol. 2017 Nov 1;135(11):1147-1155. doi: 10.1001/jamaophthalmol.2017.3407.

8.

Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery.

Yu-Wai-Man C, Owen N, Lees J, Tagalakis AD, Hart SL, Webster AR, Orengo CA, Khaw PT.

Sci Rep. 2017 Jul 17;7(1):5644. doi: 10.1038/s41598-017-05780-5.

9.

THE TRANSITION FROM MOTHER-OF-ONE TO MOTHER-OF-TWO: MOTHERS' PERCEPTIONS OF THEMSELVES AND THEIR RELATIONSHIPS WITH THEIR FIRSTBORN CHILDREN.

Chapman JK, Hart SL.

Infant Ment Health J. 2017 Jul;38(4):475-485. doi: 10.1002/imhj.21650. Epub 2017 Jun 15.

PMID:
28618010
10.

Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis.

Manunta MDI, Tagalakis AD, Attwood M, Aldossary AM, Barnes JL, Munye MM, Weng A, McAnulty RJ, Hart SL.

Sci Rep. 2017 Apr 6;7(1):700. doi: 10.1038/s41598-017-00662-2.

11.

Prospects for RNA delivery with nanotechnologies.

Hart SL.

Gene Ther. 2017 Mar;24(3):121. doi: 10.1038/gt.2017.15. No abstract available.

PMID:
28356601
12.

Proximal Foundations of Jealousy: Expectations of Exclusivity in the Infant's First Year of Life.

Hart SL.

Emot Rev. 2016 Oct;8(4):358-366. doi: 10.1177/1754073915615431. Epub 2016 Jun 21.

13.

Peptide and nucleic acid-directed self-assembly of cationic nanovehicles through giant unilamellar vesicle modification: Targetable nanocomplexes for in vivo nucleic acid delivery.

Tagalakis AD, Maeshima R, Yu-Wai-Man C, Meng J, Syed F, Wu LP, Aldossary AM, McCarthy D, Moghimi SM, Hart SL.

Acta Biomater. 2017 Mar 15;51:351-362. doi: 10.1016/j.actbio.2017.01.048. Epub 2017 Jan 18.

PMID:
28110069
14.

BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity.

Munye MM, Shoemark A, Hirst RA, Delhove JM, Sharp TV, McKay TR, O'Callaghan C, Baines DL, Howe SJ, Hart SL.

Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L258-L267. doi: 10.1152/ajplung.00471.2016. Epub 2016 Dec 15.

15.

Low-SES Preschool Children's Eyewitness Memory: The Role of Narrative Skill.

Chae Y, Kulkofsky S, Debaran F, Wang Q, Hart SL.

Behav Sci Law. 2016 Jan;34(1):55-73. doi: 10.1002/bsl.2242.

PMID:
27117601
16.

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer.

Munye MM, Tagalakis AD, Barnes JL, Brown RE, McAnulty RJ, Howe SJ, Hart SL.

Sci Rep. 2016 Mar 15;6:23125. doi: 10.1038/srep23125.

17.

Receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient delivery system for MRTF silencing in conjunctival fibrosis.

Yu-Wai-Man C, Tagalakis AD, Manunta MD, Hart SL, Khaw PT.

Sci Rep. 2016 Feb 24;6:21881. doi: 10.1038/srep21881.

18.

Systematic Comparisons of Formulations of Linear Oligolysine Peptides with siRNA and Plasmid DNA.

Kwok A, McCarthy D, Hart SL, Tagalakis AD.

Chem Biol Drug Des. 2016 May;87(5):747-63. doi: 10.1111/cbdd.12709. Epub 2016 Feb 1.

19.

In-hospital Breastfeeding and Intention to Return to Work Influence Mothers' Breastfeeding Intentions.

Thomas-Jackson SC, Bentley GE, Keyton K, Reifman A, Boylan M, Hart SL.

J Hum Lact. 2016 Nov;32(4):NP76-NP83. doi: 10.1177/0890334415597636. Epub 2016 Jul 11.

PMID:
26243753
20.

A critical role for ATF2 transcription factor in the regulation of E-selectin expression in response to non-endotoxin components of Neisseria meningitidis.

Jacobsen MC, Dusart PJ, Kotowicz K, Bajaj-Elliott M, Hart SL, Klein NJ, Dixon GL.

Cell Microbiol. 2016 Jan;18(1):66-79. doi: 10.1111/cmi.12483. Epub 2015 Jul 31.

21.

A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency.

Tagalakis AD, Castellaro S, Zhou H, Bienemann A, Munye MM, McCarthy D, White EA, Hart SL.

Int J Nanomedicine. 2015 Apr 1;10:2673-83. doi: 10.2147/IJN.S78935. eCollection 2015.

22.

Role of liposome and peptide in the synergistic enhancement of transfection with a lipopolyplex vector.

Munye MM, Ravi J, Tagalakis AD, McCarthy D, Ryadnov MG, Hart SL.

Sci Rep. 2015 Mar 19;5:9292. doi: 10.1038/srep09292.

23.

Improved intracellular delivery of peptide- and lipid-nanoplexes by natural glycosides.

Weng A, Manunta MD, Thakur M, Gilabert-Oriol R, Tagalakis AD, Eddaoudi A, Munye MM, Vink CA, Wiesner B, Eichhorst J, Melzig MF, Hart SL.

J Control Release. 2015 May 28;206:75-90. doi: 10.1016/j.jconrel.2015.03.007. Epub 2015 Mar 7.

PMID:
25758332
24.

The role of the helper lipid on the DNA transfection efficiency of lipopolyplex formulations.

Du Z, Munye MM, Tagalakis AD, Manunta MD, Hart SL.

Sci Rep. 2014 Nov 19;4:7107. doi: 10.1038/srep07107.

25.

Low-SES children's eyewitness memory: the effects of verbal labels and vocabulary skills.

Chae Y, Kulkofsky S, Debaran F, Wang Q, Hart SL.

Behav Sci Law. 2014 Nov-Dec;32(6):732-45. doi: 10.1002/bsl.2145. Epub 2014 Nov 13.

PMID:
25393768
26.

Multifunctional, self-assembling anionic peptide-lipid nanocomplexes for targeted siRNA delivery.

Tagalakis AD, Lee DH, Bienemann AS, Zhou H, Munye MM, Saraiva L, McCarthy D, Du Z, Vink CA, Maeshima R, White EA, Gustafsson K, Hart SL.

Biomaterials. 2014 Sep;35(29):8406-15. doi: 10.1016/j.biomaterials.2014.06.003. Epub 2014 Jun 28.

27.

PEGylation improves the receptor-mediated transfection efficiency of peptide-targeted, self-assembling, anionic nanocomplexes.

Tagalakis AD, Kenny GD, Bienemann AS, McCarthy D, Munye MM, Taylor H, Wyatt MJ, Lythgoe MF, White EA, Hart SL.

J Control Release. 2014 Jan 28;174:177-87. doi: 10.1016/j.jconrel.2013.11.014. Epub 2013 Nov 22.

28.

Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm.

Onoufriadis A, Shoemark A, Munye MM, James CT, Schmidts M, Patel M, Rosser EM, Bacchelli C, Beales PL, Scambler PJ, Hart SL, Danke-Roelse JE, Sloper JJ, Hull S, Hogg C, Emes RD, Pals G, Moore AT, Chung EM; UK10K, Mitchison HM.

J Med Genet. 2014 Jan;51(1):61-7. doi: 10.1136/jmedgenet-2013-101938. Epub 2013 Nov 7.

29.

Multifunctional receptor-targeted nanocomplexes for the delivery of therapeutic nucleic acids to the brain.

Kenny GD, Bienemann AS, Tagalakis AD, Pugh JA, Welser K, Campbell F, Tabor AB, Hailes HC, Gill SS, Lythgoe MF, McLeod CW, White EA, Hart SL.

Biomaterials. 2013 Dec;34(36):9190-200. doi: 10.1016/j.biomaterials.2013.07.081. Epub 2013 Aug 12.

30.

Inhibition of neointimal hyperplasia in a rabbit vein graft model following non-viral transfection with human iNOS cDNA.

Meng QH, Irvine S, Tagalakis AD, McAnulty RJ, McEwan JR, Hart SL.

Gene Ther. 2013 Oct;20(10):979-86. doi: 10.1038/gt.2013.20. Epub 2013 May 2.

31.

Airway deposition of nebulized gene delivery nanocomplexes monitored by radioimaging agents.

Manunta MD, McAnulty RJ, McDowell A, Jin J, Ridout D, Fleming J, Bottoms SE, Tossici-Bolt L, Laurent GJ, Biassoni L, O'Callaghan C, Hart SL.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):471-80. doi: 10.1165/rcmb.2013-0030OC.

32.

Comparison of nanocomplexes with branched and linear peptides for siRNA delivery.

Tagalakis AD, Saraiva L, McCarthy D, Gustafsson KT, Hart SL.

Biomacromolecules. 2013 Mar 11;14(3):761-70. doi: 10.1021/bm301842j. Epub 2013 Feb 6.

PMID:
23339543
33.

Gene delivery using ternary lipopolyplexes incorporating branched cationic peptides: the role of Peptide sequence and branching.

Welser K, Campbell F, Kudsiova L, Mohammadi A, Dawson N, Hart SL, Barlow DJ, Hailes HC, Lawrence MJ, Tabor AB.

Mol Pharm. 2013 Jan 7;10(1):127-41. doi: 10.1021/mp300187t. Epub 2012 Dec 4.

PMID:
23210981
34.

Multifunctional receptor-targeted nanocomplexes for magnetic resonance imaging and transfection of tumours.

Kenny GD, Villegas-Llerena C, Tagalakis AD, Campbell F, Welser K, Botta M, Tabor AB, Hailes HC, Lythgoe MF, Hart SL.

Biomaterials. 2012 Oct;33(29):7241-50. doi: 10.1016/j.biomaterials.2012.06.042. Epub 2012 Jul 17.

35.

Lipid peptide nanocomplexes for gene delivery and magnetic resonance imaging in the brain.

Writer MJ, Kyrtatos PG, Bienemann AS, Pugh JA, Lowe AS, Villegas-Llerena C, Kenny GD, White EA, Gill SS, McLeod CW, Lythgoe MF, Hart SL.

J Control Release. 2012 Sep 10;162(2):340-8. doi: 10.1016/j.jconrel.2012.07.002. Epub 2012 Jul 16.

36.

Somatic symptoms, peer and school stress, and family and community violence exposure among urban elementary school children.

Hart SL, Hodgkinson SC, Belcher HM, Hyman C, Cooley-Strickland M.

J Behav Med. 2013 Oct;36(5):454-65. doi: 10.1007/s10865-012-9440-2. Epub 2012 Jul 7.

37.

Meta-analysis of efficacy of interventions for elevated depressive symptoms in adults diagnosed with cancer.

Hart SL, Hoyt MA, Diefenbach M, Anderson DR, Kilbourn KM, Craft LL, Steel JL, Cuijpers P, Mohr DC, Berendsen M, Spring B, Stanton AL.

J Natl Cancer Inst. 2012 Jul 3;104(13):990-1004. doi: 10.1093/jnci/djs256. Epub 2012 Jul 5.

38.

Age-related patterns in negative affect and appraisals about colorectal cancer over time.

Hart SL, Charles ST.

Health Psychol. 2013 Mar;32(3):302-10. doi: 10.1037/a0028523. Epub 2012 May 21.

PMID:
22612558
39.

Impact of depression and anxiety on the quality of life of constipated patients.

Albiani JJ, Hart SL, Katz L, Berian J, Del Rosario A, Lee J, Varma M.

J Clin Psychol Med Settings. 2013 Mar;20(1):123-32. doi: 10.1007/s10880-012-9306-3.

PMID:
22581107
40.

Elemental imaging of MRI contrast agents: benchmarking of LA-ICP-MS to MRI.

Pugh JA, Cox AG, McLeod CW, Bunch J, Writer MJ, Hart SL, Bienemann A, White E, Bell J.

Anal Bioanal Chem. 2012 Jun;403(6):1641-9. doi: 10.1007/s00216-012-5973-z. Epub 2012 Apr 18.

PMID:
22526651
41.

Cancer perceptions: implications from the 2007 Health Information National Trends Survey.

Kowalkowski MA, Hart SL, Du XL, Baraniuk S, Latini DM.

J Cancer Surviv. 2012 Sep;6(3):287-95. doi: 10.1007/s11764-012-0217-y. Epub 2012 Mar 29.

PMID:
22457218
42.

A randomized controlled trial of anorectal biofeedback for constipation.

Hart SL, Lee JW, Berian J, Patterson TR, Del Rosario A, Varma MG.

Int J Colorectal Dis. 2012 Apr;27(4):459-66. doi: 10.1007/s00384-011-1355-9. Epub 2011 Dec 9.

PMID:
22159695
43.

Development and assessment of the constipation-related disability scale.

Hart SL, Albiani JJ, Crangle CJ, Torbit LA, Varma MG.

Aliment Pharmacol Ther. 2012 Jan;35(1):183-92. doi: 10.1111/j.1365-2036.2011.04910.x. Epub 2011 Nov 17.

44.

Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium.

Manunta MD, McAnulty RJ, Tagalakis AD, Bottoms SE, Campbell F, Hailes HC, Tabor AB, Laurent GJ, O'Callaghan C, Hart SL.

PLoS One. 2011;6(10):e26768. doi: 10.1371/journal.pone.0026768. Epub 2011 Oct 26.

45.

Moderators of cancer-related distress and worry after a pancreatic cancer genetic counseling and screening intervention.

Hart SL, Torbit LA, Crangle CJ, Esplen MJ, Holter S, Semotiuk K, Borgida A, Ardiles P, Rothenmund H, Gallinger S.

Psychooncology. 2012 Dec;21(12):1324-30. doi: 10.1002/pon.2026. Epub 2011 Jul 20.

PMID:
21774034
46.

Compromised weight gain, milk intake, and feeding behavior in breastfed newborns of depressive mothers.

Hart SL, Jackson SC, Boylan LM.

J Pediatr Psychol. 2011 Sep;36(8):942-50. doi: 10.1093/jpepsy/jsr031. Epub 2011 Jun 3.

47.

Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery.

Tagalakis AD, He L, Saraiva L, Gustafsson KT, Hart SL.

Biomaterials. 2011 Sep;32(26):6302-15. doi: 10.1016/j.biomaterials.2011.05.022. Epub 2011 May 31.

PMID:
21624650
48.

Improvements in partner support predict sexual satisfaction among individuals with multiple sclerosis.

Blackmore DE, Hart SL, Albiani JJ, Mohr DC.

Rehabil Psychol. 2011 May;56(2):117-22. doi: 10.1037/a0023362.

49.

Gender-specific differences in pelvic organ function after proctectomy for inflammatory bowel disease.

Wang JY, Hart SL, Wilkowski KS, Lee JW, Delmotte EC, del Rosario KM, del Rosario AS, Varma MG.

Dis Colon Rectum. 2011 Jan;54(1):66-76. doi: 10.1007/DCR.0b013e3181fd48d2.

PMID:
21160316
50.

Integrin-targeted nanocomplexes for tumour specific delivery and therapy by systemic administration.

Tagalakis AD, Grosse SM, Meng QH, Mustapa MF, Kwok A, Salehi SE, Tabor AB, Hailes HC, Hart SL.

Biomaterials. 2011 Feb;32(5):1370-6. doi: 10.1016/j.biomaterials.2010.10.037. Epub 2010 Nov 12.

PMID:
21074847

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