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Modelling Survival of Patients Treated with Adjuvant Nivolumab Who Have Melanoma with Lymph Node Involvement or Metastatic Disease After Complete Resection.

Batteson R, Hart R, Hemstock M, Gooden K, Kotapati S, Roze S, Lee D, Amadi A.

Pharmacoecon Open. 2019 Oct 5. doi: 10.1007/s41669-019-00181-y. [Epub ahead of print]


Ecophysiological Plasticity and Cold Stress Adaptation in Himalayan Alpine Herbs: Bistorta affinis and Sibbaldia procumbens.

Rahman IU, Hart R, Afzal A, Iqbal Z, Alqarawi AA, Abd Allah EF, Hashem A, Ijaz F, Ali N, Calixto ES.

Plants (Basel). 2019 Sep 27;8(10). pii: E378. doi: 10.3390/plants8100378.


Major Bleeding in Patients With Coronary or Peripheral Artery Disease Treated With Rivaroxaban Plus Aspirin.

Eikelboom JW, Bosch JJ, Connolly SJ, Shestakovska O, Dagenais GR, Hart RG, Leong DP, O'Donnell M, Fox KAA, Bhatt DL, Cairns JA, Tasto C, Berkowitz SD, Cook Bruns N, Muehlhofer E, Diaz R, Maggioni AP, Yusuf S.

J Am Coll Cardiol. 2019 Sep 24;74(12):1519-1528. doi: 10.1016/j.jacc.2019.07.065.


Aortic Arch Atherosclerosis in Patients With Embolic Stroke of Undetermined Source: An Exploratory Analysis of the NAVIGATE ESUS Trial.

Ntaios G, Pearce LA, Meseguer E, Endres M, Amarenco P, Ozturk S, Lang W, Bornstein NM, Molina CA, Pagola J, Mundl H, Berkowitz SD, Liu YY, Sen S, Connolly SJ, Hart RG; NAVIGATE ESUS Investigators.

Stroke. 2019 Sep 17:STROKEAHA119025813. doi: 10.1161/STROKEAHA.119.025813. [Epub ahead of print]


Association Between Low-Dose Rivaroxaban With or Without Aspirin and Ischemic Stroke Subtypes: A Secondary Analysis of the COMPASS Trial.

Perera KS, Ng KKH, Nayar S, Catanese L, Dyal L, Sharma M, Connolly SJ, Yusuf S, Bosch J, Eikelboom JW, Hart RG.

JAMA Neurol. 2019 Sep 16. doi: 10.1001/jamaneurol.2019.2984. [Epub ahead of print]


Effective Prevention of Proximal Junctional Failure in Adult Spinal Deformity Surgery Requires a Combination of Surgical Implant Prophylaxis and Avoidance of Sagittal Alignment Overcorrection.

Line BG, Bess S, Lafage R, Lafage V, Schwab F, Ames C, Kim HJ, Kelly M, Gupta M, Burton D, Hart R, Klineberg E, Kebaish K, Hostin R, Eastlack R, Shaffrey C, Smith JS; International Spine Study Group.

Spine (Phila Pa 1976). 2019 Sep 12. doi: 10.1097/BRS.0000000000003249. [Epub ahead of print]


A brief update on the evidence supporting the treatment of infertility in polycystic ovary syndrome.

Costello MF, Misso ML, Balen A, Boyle J, Devoto L, Garad RM, Hart R, Johnson L, Jordan C, Legro RS, Norman RJ, Moran L, Mocanu E, Qiao J, Rodgers RJ, Rombauts L, Tassone EC, Thangaratinam S, Vanky E, Teede HJ.

Aust N Z J Obstet Gynaecol. 2019 Sep 12. doi: 10.1111/ajo.13051. [Epub ahead of print]


Should Sagittal Spinal Alignment Targets for Adult Spinal Deformity Correction Depend on Pelvic Incidence and Age?

Protopsaltis TS, Soroceanu A, Tishelman JC, Buckland AJ, Mundis GM Jr, Smith JS, Daniels A, Lenke LG, Kim HJ, Klineberg EO, Ames CP, Hart RA, Bess S, Shaffrey CI, Schwab FJ, Lafage V; International Spine Study Group (ISSG).

Spine (Phila Pa 1976). 2019 Sep 6. doi: 10.1097/BRS.0000000000003237. [Epub ahead of print]


The Importance of C2-Slope, a Singular Marker of Cervical Deformity, Correlates with Patient Reported Outcomes.

Protopsaltis TS, Ramchandran S, Tishelman JC, Smith JS, Neuman BJ, Mundis GM Jr, Lafage R, Klineberg EO, Hamilton DK, LaFage V, Gupta MC, Hart RA, Schwab FJ, Burton DC, Bess S, Shaffrey CI, Ames CP; International Spine Study Group.

Spine (Phila Pa 1976). 2019 Sep 6. doi: 10.1097/BRS.0000000000003214. [Epub ahead of print]


Bleeding and New Cancer Diagnosis in Patients with Atherosclerosis.

Eikelboom JW, Connolly SJ, Bosch J, Shestakovska O, Aboyans V, Alings M, Anand SS, Avezum A, Berkowitz SD, Bhatt DL, Cook Bruns N, Felix C, Fox KAA, Hart RG, Maggioni AP, Moayyedi P, O'Donnell M, Rydén L, Verhamme P, Widimsky P, Zhu J, Yusuf S; COMPASS investigators.

Circulation. 2019 Sep 12. doi: 10.1161/CIRCULATIONAHA.119.041949. [Epub ahead of print]


A Review of First Line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome.

Costello M, Garad R, Hart R, Homer H, Johnson L, Jordan C, Mocanu E, Qiao J, Rombauts L, Teede HJ, Vanky E, Venetis C, Ledger W.

Med Sci (Basel). 2019 Sep 10;7(9). pii: E95. doi: 10.3390/medsci7090095. Review.


The Role of Potentially Modifiable Factors in a Standard Work Protocol to Decrease Complications in Adult Spinal Deformity Surgery: A Systematic Review, Part 2.

Sethi RK, Burton DC, Wright AK, Lenke LG, Cerpa M, Kelly MP, Daniels AH, Ames CP, Klineberg EO, Mundis GM, Bess S, Hart RA; ISSG.

Spine Deform. 2019 Sep;7(5):684-695. doi: 10.1016/j.jspd.2019.03.001.


The Role of Potentially Modifiable Factors in a Standard Work Protocol to Decrease Complications in Adult Spinal Deformity Surgery: A Systematic Review, Part 1.

Burton DC, Sethi RK, Wright AK, Daniels AH, Ames CP, Reid DB, Klineberg EO, Harper R, Mundis GM, Hlubek RJ, Bess S, Hart RA, Kelly MP, Lenke LG.

Spine Deform. 2019 Sep;7(5):669-683. doi: 10.1016/j.jspd.2019.04.003.


Evidence summaries and recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome: assessment and treatment of infertility.

Costello MF, Misso ML, Balen A, Boyle J, Devoto L, Garad RM, Hart R, Johnson L, Jordan C, Legro RS, Norman RJ, Mocanu E, Qiao J, Rodgers RJ, Rombauts L, Tassone EC, Thangaratinam S, Vanky E, Teede HJ; International PCOS Network.

Hum Reprod Open. 2019 Jan 4;2019(1):hoy021. doi: 10.1093/hropen/hoy021. eCollection 2019.


Improvement in Glycemic and Lipid Profiles in Type 2 Diabetics with a 90-Day Ketogenic Diet.

Walton CM, Perry K, Hart RH, Berry SL, Bikman BT.

J Diabetes Res. 2019 Aug 14;2019:8681959. doi: 10.1155/2019/8681959. eCollection 2019.


Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neurons.

Halikere A, Popova D, Scarnati MS, Hamod A, Swerdel MR, Moore JC, Tischfield JA, Hart RP, Pang ZP.

Mol Psychiatry. 2019 Sep 3. doi: 10.1038/s41380-019-0507-0. [Epub ahead of print]


Systematic review and meta-analysis of T1 glottic cancer outcomes comparing CO2 transoral laser microsurgery and radiotherapy.

Vaculik MF, MacKay CA, Taylor SM, Trites JRB, Hart RD, Rigby MH.

J Otolaryngol Head Neck Surg. 2019 Sep 3;48(1):44. doi: 10.1186/s40463-019-0367-2.


Younger Patients Are Differentially Affected by Stiffness-Related Disability Following Adult Spinal Deformity Surgery.

Durand WM, Daniels AH, Hamilton DK, Passias PG, Kim HJ, Protopsaltis T, Lafage V, Smith JS, Shaffrey C, Gupta M, Kelly MP, Klineberg E, Schwab F, Burton D, Bess S, Ames C, Hart R; International Spine Study Group.

World Neurosurg. 2019 Aug 31. pii: S1878-8750(19)32325-3. doi: 10.1016/j.wneu.2019.08.169. [Epub ahead of print]


Non-AIDS comorbidity burden differs by sex, race, and insurance type in aging adults in HIV care.

Palella FJ Jr, Hart R, Armon C, Tedaldi E, Yangco B, Novak R, Battalora L, Ward D, Li J, Buchacz K; HIV Outpatient Study (HOPS).

AIDS. 2019 Aug 22. doi: 10.1097/QAD.0000000000002349. [Epub ahead of print]


Characterisation of hybrid yeasts for the production of varietal Sauvignon blanc wine - A review.

Hart RS, Jolly NP, Ndimba BK.

J Microbiol Methods. 2019 Aug 22;165:105699. doi: 10.1016/j.mimet.2019.105699. [Epub ahead of print] Review.


Incidence and Risk Factors for Renal Disease in an Outpatient Cohort of HIV-Infected Patients on Antiretroviral Therapy.

Doshi S, Ucanda M, Hart R, Hou Q, Terzian AS; DC Cohort Executive Committee.

Kidney Int Rep. 2019 May 7;4(8):1075-1084. doi: 10.1016/j.ekir.2019.04.024. eCollection 2019 Aug.


In-utero Exposure to Maternal Stressful Life Events and Risk of Cryptorchidism: The Raine Study.

Bräuner EV, Hickey M, Hansen ÅM, Doherty DA, Handelsman DJ, Juul A, Hart R.

Front Endocrinol (Lausanne). 2019 Aug 2;10:530. doi: 10.3389/fendo.2019.00530. eCollection 2019.


Predicting extended operative time and length of inpatient stay in cervical deformity corrective surgery.

Horn SR, Passias PG, Bortz CA, Pierce KE, Lafage V, Lafage R, Brown AE, Alas H, Smith JS, Line B, Deviren V, Mundis GM, Kelly MP, Kim HJ, Protopsaltis T, Daniels AH, Klineberg EO, Burton DC, Hart RA, Schwab FJ, Bess S, Shaffrey CI, Ames CP; International Spine Study Group.

J Clin Neurosci. 2019 Aug 8. pii: S0967-5868(19)30304-2. doi: 10.1016/j.jocn.2019.07.064. [Epub ahead of print]


Efficacy and Safety of Rivaroxaban Versus Aspirin in Embolic Stroke of Undetermined Source and Carotid Atherosclerosis.

Ntaios G, Swaminathan B, Berkowitz SD, Gagliardi RJ, Lang W, Siegler JE, Lavados P, Mundl H, Bornstein N, Meseguer E, Amarenco P, Cucchiara B, Camps-Renom P, Makaritsis K, Korompoki E, Papavasileiou V, Marti-Fabregas J, Milionis H, Vemmos K, Connolly SJ, Hart RG; NAVIGATE ESUS Investigators.

Stroke. 2019 Sep;50(9):2477-2485. doi: 10.1161/STROKEAHA.119.025168. Epub 2019 Aug 12.


Clinical exome sequencing vs. usual care for hereditary colorectal cancer diagnosis: A pilot comparative effectiveness study.

Niu X, Amendola LM, Hart R, Bennette CS, Heagerty P, Horike-Pyne M, Trinidad SB, Rosenthal EA, Comstock B, Nefcy C, Hisama FM, Bennett RL, Grady WM, Gallego CJ, Tarczy-Hornoch P, Fullerton SM, Burke W, Regier DA, Dorschner MO, Shirts BH, Robertson PD, Nickerson DA, Patrick DL, Jarvik GP, Veenstra DL.

Contemp Clin Trials. 2019 Sep;84:105820. doi: 10.1016/j.cct.2019.105820. Epub 2019 Aug 7.


Use of Growth Hormone in the IVF Treatment of Women With Poor Ovarian Reserve.

Hart RJ.

Front Endocrinol (Lausanne). 2019 Jul 24;10:500. doi: 10.3389/fendo.2019.00500. eCollection 2019. Review.


Myoelectric signal from below the level of spinal cord injury as a command source for an implanted upper extremity neuroprosthesis - a case report.

Heald E, Kilgore K, Hart R, Moss C, Peckham PH.

J Neuroeng Rehabil. 2019 Aug 2;16(1):100. doi: 10.1186/s12984-019-0571-3.


Development of a Novel Cervical Deformity Surgical Invasiveness Index.

Passias PG, Horn SR, Soroceanu A, Oh C, Ailon T, Neuman BJ, Lafage V, Lafage R, Smith JS, Line B, Bortz CA, Segreto FA, Brown A, Alas H, Pierce KE, Eastlack RK, Sciubba DM, Protopsaltis TS, Klineberg EO, Burton DC, Hart RA, Schwab FJ, Bess S, Shaffrey CI, Ames CP; International Spine Study Group.

Spine (Phila Pa 1976). 2019 Jul 29. doi: 10.1097/BRS.0000000000003175. [Epub ahead of print]


Randomized Trial of Standard Adjuvant Chemotherapy Regimens Versus Capecitabine in Older Women With Early Breast Cancer: 10-Year Update of the CALGB 49907 Trial.

Muss HB, Polley MC, Berry DA, Liu H, Cirrincione CT, Theodoulou M, Mauer AM, Kornblith AB, Partridge AH, Dressler LG, Cohen HJ, Kartcheske PA, Perez EA, Wolff AC, Gralow JR, Burstein HJ, Mahmood AA, Sutton LM, Magrinat G, Parker BA, Hart RD, Grenier D, Hurria A, Jatoi A, Norton L, Hudis CA, Winer EP, Carey L.

J Clin Oncol. 2019 Sep 10;37(26):2338-2348. doi: 10.1200/JCO.19.00647. Epub 2019 Jul 24.


Traditional Herbal Knowledge among the Inhabitants: A Case Study in Urgam Valley of Chamoli Garhwal, Uttarakhand, India.

Singh A, Hart R, Chandra S, Nautiyal MC, Sayok AK.

Evid Based Complement Alternat Med. 2019 Jun 3;2019:5656925. doi: 10.1155/2019/5656925. eCollection 2019.


A Review of Second- and Third-line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome.

Costello MF, Garad RM, Hart R, Homer H, Johnson L, Jordan C, Mocanu E, Qiao J, Rombauts L, Teede HJ, Vanky E, Venetis CA, Ledger WL.

Med Sci (Basel). 2019 Jun 26;7(7). pii: E75. doi: 10.3390/medsci7070075. Review.


Translation and implementation of the Australian-led PCOS guideline: clinical summary and translation resources from the International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome.

Teede HJ, Misso ML, Boyle JA, Garad RM, McAllister V, Downes L, Gibson-Helm M, Hart RJ, Rombauts L, Moran L, Dokras A, Laven J, Piltonen T, Rodgers RJ, Thondan M, Costello MF, Norman RJ; International PCOS Network.

Med J Aust. 2018 Oct;209 Suppl 7:S3-S8. doi: 10.5694/mja18.00656.


Parent Intent and Willingness to Immunize Children Against Influenza in the Pediatric Emergency Department.

Hart RJ, Paul RI, Levine A, Sikes K, Bryant K, Stevenson MD.

Pediatr Emerg Care. 2019 Jul;35(7):493-497. doi: 10.1097/PEC.0000000000001869.


Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages.

Aly ASI, Deveci G, Yilmaz I, Abraham A, Golshan A, Hart RJ.

J Vis Exp. 2019 May 30;(147). doi: 10.3791/55688.


Comparison of Best Versus Worst Clinical Outcomes for Adult Cervical Deformity Surgery.

Smith JS, Shaffrey CI, Kim HJ, Passias P, Protopsaltis T, Lafage R, Mundis GM Jr, Klineberg E, Lafage V, Schwab FJ, Scheer JK, Kelly M, Hamilton DK, Gupta M, Deviren V, Hostin R, Albert T, Riew KD, Hart R, Burton D, Bess S, Ames CP.

Global Spine J. 2019 May;9(3):303-314. doi: 10.1177/2192568218794164. Epub 2018 Aug 16.


Roles of the Clinical Ethics Consultant: A Response to Kornfeld and Prager.

Vaughan DM, Permar R, Rakestraw C, Hart R, Griffin LC, Winslade WJ.

J Clin Ethics. 2019 Summer;30(2):117-120.


Oncological and functional outcomes following transoral laser microsurgery in patients with T2a vs T2b glottic squamous cell carcinoma.

Forner D, Rigby MH, Hart RD, Trites JR, Taylor SM.

J Otolaryngol Head Neck Surg. 2019 Jun 7;48(1):27. doi: 10.1186/s40463-019-0346-7.


Incidence of Acute, Progressive, and Delayed Proximal Junctional Kyphosis Over an 8-Year Period in Adult Spinal Deformity Patients.

Segreto FA, Passias PG, Lafage R, Lafage V, Smith JS, Line BG, Mundis GM, Bortz CA, Stekas ND, Horn SR, Diebo BG, Brown AE, Ihejirika Y, Nunley PD, Daniels AH, Gupta MC, Gum JL, Hamilton DK, Klineberg EO, Burton DC, Hart RA, Schwab FJ, Bess S, Shaffrey CI, Ames CP.

Oper Neurosurg (Hagerstown). 2019 Jun 7. pii: opz128. doi: 10.1093/ons/opz128. [Epub ahead of print]


Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter.

Zhu Y, Zou X, Dean AE, Brien JO, Gao Y, Tran EL, Park SH, Liu G, Kieffer MB, Jiang H, Stauffer ME, Hart R, Quan S, Satchell KJF, Horikoshi N, Bonini M, Gius D.

Nat Commun. 2019 Jun 3;10(1):2399. doi: 10.1038/s41467-019-10352-4.


Predictors of Recurrent Ischemic Stroke in Patients with Embolic Strokes of Undetermined Source and Effects of Rivaroxaban Versus Aspirin According to Risk Status: The NAVIGATE ESUS Trial.

Hart RG, Veltkamp RC, Sheridan P, Sharma M, Kasner SE, Bangdiwala SI, Ntaios G, Shoamanesh A, Ameriso SF, Toni D, Czlonkowska A, Lindgren A, Hankey GJ, Perera KS, Shuaib A, Coutts SB, Gagliardi RJ, Berkowitz SD, Mundl H, Peters G, Connolly SJ; NAVIGATE ESUS Investigators.

J Stroke Cerebrovasc Dis. 2019 Aug;28(8):2273-2279. doi: 10.1016/j.jstrokecerebrovasdis.2019.05.014. Epub 2019 May 31.


Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin.

Moayyedi P, Eikelboom JW, Bosch J, Connolly SJ, Dyal L, Shestakovska O, Leong D, Anand SS, Störk S, Branch KRH, Bhatt DL, Verhamme PB, O'Donnell M, Maggioni AP, Lonn EM, Piegas LS, Ertl G, Keltai M, Bruns NC, Muehlhofer E, Dagenais GR, Kim JH, Hori M, Steg PG, Hart RG, Diaz R, Alings M, Widimsky P, Avezum A, Probstfield J, Zhu J, Liang Y, Lopez-Jaramillo P, Kakkar AK, Parkhomenko AN, Ryden L, Pogosova N, Dans AL, Lanas F, Commerford PJ, Torp-Pedersen C, Guzik TJ, Vinereanu D, Tonkin AM, Lewis BS, Felix C, Yusoff K, Metsarinne KP, Fox KAA, Yusuf S; COMPASS Investigators.

Gastroenterology. 2019 Sep;157(3):682-691.e2. doi: 10.1053/j.gastro.2019.05.056. Epub 2019 May 29.


Who says "no" to participating in stroke clinical trials and why: an observational study from the Vancouver Stroke Program.

O'Neill ZR, Deptuck HM, Quong L, Maclean G, Villaluna K, King-Azote P, Sharma M, Butcher K, Hart RG, Field TS.

Trials. 2019 May 31;20(1):313. doi: 10.1186/s13063-019-3434-0.


Food craving, cortisol and ghrelin responses in modeling highly palatable snack intake in the laboratory.

Sinha R, Gu P, Hart R, Guarnaccia JB.

Physiol Behav. 2019 Sep 1;208:112563. doi: 10.1016/j.physbeh.2019.112563. Epub 2019 May 27.


The association between in-utero exposure to stressful life events during pregnancy and male reproductive function in a cohort of 20-year-old offspring: The Raine Study.

Bräuner EV, Hansen ÅM, Doherty DA, Dickinson JE, Handelsman DJ, Hickey M, Skakkebæk NE, Juul A, Hart R.

Hum Reprod. 2019 Jul 8;34(7):1345-1355. doi: 10.1093/humrep/dez070.


Are obstetric and gynaecological trainees in Australia and New Zealand adequately trained in the management of the infertile couple?

Robertson P, Pontré J, Tucker P, Hart R.

Aust N Z J Obstet Gynaecol. 2019 Aug;59(4):580-584. doi: 10.1111/ajo.12989. Epub 2019 May 29.


Branch atheromatous disease diagnosed as embolic stroke of undetermined source: A sub-analysis of NAVIGATE ESUS.

Uchiyama S, Toyoda K, Kitagawa K, Okada Y, Ameriso S, Mundl H, Berkowitz S, Yamada T, Liu YY, Hart RG; NAVIGATE ESUS Investigators.

Int J Stroke. 2019 May 27:1747493019852177. doi: 10.1177/1747493019852177. [Epub ahead of print]


OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome.

Xu R, Brawner AT, Li S, Liu JJ, Kim H, Xue H, Pang ZP, Kim WY, Hart RP, Liu Y, Jiang P.

Cell Stem Cell. 2019 Jun 6;24(6):908-926.e8. doi: 10.1016/j.stem.2019.04.014. Epub 2019 May 23.


An Unusual Case of Mandibular Squamous Cell Carcinoma in Intimacy with an Impacted Wisdom Tooth.

Cheung J, Al Afif A, Bullock MJ, Robertson C, Hart R, Goodday R.

Case Rep Surg. 2019 Apr 11;2019:8360357. doi: 10.1155/2019/8360357. eCollection 2019.


The Genomic Medicine Integrative Research Framework: A Conceptual Framework for Conducting Genomic Medicine Research.

Horowitz CR, Orlando LA, Slavotinek AM, Peterson J, Angelo F, Biesecker B, Bonham VL, Cameron LD, Fullerton SM, Gelb BD, Goddard KAB, Hailu B, Hart R, Hindorff LA, Jarvik GP, Kaufman D, Kenny EE, Knight SJ, Koenig BA, Korf BR, Madden E, McGuire AL, Ou J, Wasserstein MP, Robinson M, Leventhal H, Sanderson SC.

Am J Hum Genet. 2019 Jun 6;104(6):1088-1096. doi: 10.1016/j.ajhg.2019.04.006. Epub 2019 May 16.


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