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Items: 20

1.

Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk.

Hart PC, Kenny HA, Grassl N, Watters KM, Litchfield LM, Coscia F, Blaženović I, Ploetzky L, Fiehn O, Mann M, Lengyel E, Romero IL.

Cell Rep. 2019 Dec 17;29(12):4086-4098.e6. doi: 10.1016/j.celrep.2019.11.079.

2.

SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.

He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23534-23541. doi: 10.1073/pnas.1902308116. Epub 2019 Oct 7.

PMID:
31591207
3.

Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.

Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, Nomura DK, Bonini MG, Locasale JW, Rosner MR.

Nature. 2019 Apr;568(7751):254-258. doi: 10.1038/s41586-019-1005-x. Epub 2019 Mar 6.

4.

Inhibition of fascin in cancer and stromal cells blocks ovarian cancer metastasis.

McGuire S, Kara B, Hart PC, Montag A, Wroblewski K, Fazal S, Huang XY, Lengyel E, Kenny HA.

Gynecol Oncol. 2019 May;153(2):405-415. doi: 10.1016/j.ygyno.2019.01.020. Epub 2019 Feb 20.

PMID:
30797592
5.

SPHK1 Is a Novel Target of Metformin in Ovarian Cancer.

Hart PC, Chiyoda T, Liu X, Weigert M, Curtis M, Chiang CY, Loth R, Lastra R, McGregor SM, Locasale JW, Lengyel E, Romero IL.

Mol Cancer Res. 2019 Apr;17(4):870-881. doi: 10.1158/1541-7786.MCR-18-0409. Epub 2019 Jan 17.

PMID:
30655321
6.

Allele-specific interaction between glutathione peroxidase 1 and manganese superoxide dismutase affects the levels of Bcl-2, Sirt3 and E-cadherin.

Ekoue DN, Bera S, Ansong E, Hart PC, Zaichick S, Domann FE, Bonini MG, Diamond AM.

Free Radic Res. 2017 Jun;51(6):582-590. doi: 10.1080/10715762.2017.1339303. Epub 2017 Jul 4.

7.

Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.

Chiyoda T, Hart PC, Eckert MA, McGregor SM, Lastra RR, Hamamoto R, Nakamura Y, Yamada SD, Olopade OI, Lengyel E, Romero IL.

Cancer Prev Res (Phila). 2017 Apr;10(4):255-266. doi: 10.1158/1940-6207.CAPR-16-0281. Epub 2017 Mar 6.

8.

SOD2 and the Mitochondrial UPR: Partners Regulating Cellular Phenotypic Transitions.

He C, Hart PC, Germain D, Bonini MG.

Trends Biochem Sci. 2016 Jul;41(7):568-577. doi: 10.1016/j.tibs.2016.04.004. Epub 2016 May 11.

9.

Experimental Models of Anxiety for Drug Discovery and Brain Research.

Hart PC, Bergner CL, Smolinsky AN, Dufour BD, Egan RJ, LaPorte JL, Kalueff AV.

Methods Mol Biol. 2016;1438:271-91. doi: 10.1007/978-1-4939-3661-8_16. Review.

PMID:
27150096
10.

Mouse Models for Studying Depression-Like States and Antidepressant Drugs.

Bergner CL, Smolinsky AN, Hart PC, Dufour BD, Egan RJ, LaPorte JL, Kalueff AV.

Methods Mol Biol. 2016;1438:255-69. doi: 10.1007/978-1-4939-3661-8_15.

PMID:
27150095
11.

Caveolin-1 regulates cancer cell metabolism via scavenging Nrf2 and suppressing MnSOD-driven glycolysis.

Hart PC, Ratti BA, Mao M, Ansenberger-Fricano K, Shajahan-Haq AN, Tyner AL, Minshall RD, Bonini MG.

Oncotarget. 2016 Jan 5;7(1):308-22. doi: 10.18632/oncotarget.5687.

12.

NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.

Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG.

J Exp Med. 2015 Sep 21;212(10):1725-38. doi: 10.1084/jem.20140654. Epub 2015 Aug 31.

13.

MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer.

Hart PC, Mao M, de Abreu AL, Ansenberger-Fricano K, Ekoue DN, Ganini D, Kajdacsy-Balla A, Diamond AM, Minshall RD, Consolaro ME, Santos JH, Bonini MG.

Nat Commun. 2015 Feb 5;6:6053. doi: 10.1038/ncomms7053.

14.

Redox control of enzymatic functions: The electronics of life's circuitry.

Bonini MG, Consolaro MEL, Hart PC, Mao M, de Abreu ALP, Master AM.

IUBMB Life. 2014 Mar;66(3):167-181. doi: 10.1002/iub.1258. Epub 2014 Mar 26. Review.

15.

Experimental models of anxiety for drug discovery and brain research.

Hart PC, Bergner CL, Smolinsky AN, Dufour BD, Egan RJ, Laporte JL, Kalueff AV.

Methods Mol Biol. 2010;602:299-321. doi: 10.1007/978-1-60761-058-8_18. Review.

PMID:
20012406
16.

Mouse models for studying depression-like states and antidepressant drugs.

Bergner CL, Smolinsky AN, Hart PC, Dufour BD, Egan RJ, Laporte JL, Kalueff AV.

Methods Mol Biol. 2010;602:267-82. doi: 10.1007/978-1-60761-058-8_16.

PMID:
20012404
17.

Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish.

Egan RJ, Bergner CL, Hart PC, Cachat JM, Canavello PR, Elegante MF, Elkhayat SI, Bartels BK, Tien AK, Tien DH, Mohnot S, Beeson E, Glasgow E, Amri H, Zukowska Z, Kalueff AV.

Behav Brain Res. 2009 Dec 14;205(1):38-44. doi: 10.1016/j.bbr.2009.06.022. Epub 2009 Jun 18.

18.

Qui non proficit, deficit: experimental models for 'integrative' research of affective disorders.

LaPorte JL, Egan RJ, Hart PC, Bergner CL, Cachat JM, Canavello PR, Kalueff AV.

J Affect Disord. 2010 Feb;121(1-2):1-9. doi: 10.1016/j.jad.2009.04.010. Epub 2009 May 9. Review.

PMID:
19428115
19.

Influence of anabolic steroids versus effect of glucose on muscular degeneration in pigs.

HART PC, KROESKE D, SYBESMA W, vd VEEN HE.

Nature. 1963 May 18;198:716. No abstract available.

PMID:
13953042
20.

Experiments on the effect of protein on the action of methylthiouracil.

VAN DER VEEN HE, HART PC.

Acta Endocrinol (Copenh). 1953 Jul;13(3):202-6. No abstract available.

PMID:
13079551

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