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Items: 1 to 50 of 426

1.

Chemoenzymatic synthesis of the oligosaccharide moiety of the tumor-associated antigen disialosyl globopentaosylceramide.

't Hart IME, Li T, Wolfert MA, Wang S, Moremen KW, Boons GJ.

Org Biomol Chem. 2019 Aug 7;17(31):7304-7308. doi: 10.1039/c9ob01368g.

PMID:
31339142
2.

The recall of dementia-related and neutral words by people with dementia: The ironic process of thought suppression.

Cheston R, Dodd E, Hart I, Christopher G.

Int J Geriatr Psychiatry. 2019 May;34(5):756-764. doi: 10.1002/gps.5083. Epub 2019 Mar 26.

PMID:
30734372
3.

Biopharmaceutical Industry Approaches to Facility Segregation for Viral Safety: An Effort from the Consortium on Adventitious Agent Contamination in Biomanufacturing.

Barone PW, Avgerinos S, Ballard R, Brussel A, Clark P, Dowd C, Gerentes L, Hart I, Keumurian FJ, Kindermann J, Leung JC, Ly N, Mink S, Minning S, Mullberg J, Murphy M, Nöske K, Parriott S, Shum B, Wiebe ME, Springs SL.

PDA J Pharm Sci Technol. 2019 Mar-Apr;73(2):191-203. doi: 10.5731/pdajpst.2018.008862. Epub 2018 Oct 25.

PMID:
30361281
4.

Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study.

McGill F, Griffiths MJ, Bonnett LJ, Geretti AM, Michael BD, Beeching NJ, McKee D, Scarlett P, Hart IJ, Mutton KJ, Jung A, Adan G, Gummery A, Sulaiman WAW, Ennis K, Martin AP, Haycox A, Miller A, Solomon T; UK Meningitis Study Investigators.

Lancet Infect Dis. 2018 Sep;18(9):992-1003. doi: 10.1016/S1473-3099(18)30245-7. Epub 2018 Jun 29.

5.

Endothelial FAK is required for tumour angiogenesis.

Tavora B, Batista S, Reynolds LE, Jadeja S, Robinson S, Kostourou V, Hart I, Fruttiger M, Parsons M, Hodivala-Dilke KM.

EMBO Mol Med. 2016 Oct 4;8(10):1229. doi: 10.15252/emmm.201606907. Print 2016 Oct. No abstract available.

6.

Corrigendum: Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.

Barrow-McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche BA, Noval AJ, Mai A, Guzmán C, Robbez-Masson L, Iturrioz X, Hulit J, Brennan CH, Hart IR, Parker PJ, Ivaska J, Kermorgant S.

Nat Commun. 2016 Jul 22;7:12392. doi: 10.1038/ncomms12392. No abstract available.

7.

Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.

Barrow-McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche BA, Noval AJ, Mai A, Guzmán C, Robbez-Masson L, Iturrioz X, Hulit J, Brennan CH, Hart IR, Parker PJ, Ivaska J, Kermorgant S.

Nat Commun. 2016 Jun 23;7:11942. doi: 10.1038/ncomms11942. Erratum in: Nat Commun. 2016 Jul 22;7:12392. Robert-Masson, Luisa [corrected to Robbez, Masson].

8.

Synthesis and biological evaluation of negative allosteric modulators of the Kv11.1(hERG) channel.

Yu Z, van Veldhoven JP, 't Hart IM, Kopf AH, Heitman LH, IJzerman AP.

Eur J Med Chem. 2015 Dec 1;106:50-9. doi: 10.1016/j.ejmech.2015.10.032. Epub 2015 Oct 21.

PMID:
26519929
9.

Structure-Affinity Relationships (SARs) and Structure-Kinetics Relationships (SKRs) of Kv11.1 Blockers.

Yu Z, van Veldhoven JP, Louvel J, 't Hart IM, Rook MB, van der Heyden MA, Heitman LH, IJzerman AP.

J Med Chem. 2015 Aug 13;58(15):5916-29. doi: 10.1021/acs.jmedchem.5b00518. Epub 2015 Jul 17.

PMID:
26125327
10.

CD56+ T cells are increased in kidney transplant patients following cytomegalovirus infection.

Almehmadi M, Hammad A, Heyworth S, Moberly J, Middleton D, Hopkins MJ, Hart IJ, Christmas SE.

Transpl Infect Dis. 2015 Aug;17(4):518-26. doi: 10.1111/tid.12405. Epub 2015 Jul 3.

PMID:
26039898
11.

Therapeutic targeting of integrin αvβ6 in breast cancer.

Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR, Haider S, Brouilette K, Saha A, Vallath S, Bowen R, Chelala C, Eccles D, Tapper WJ, Thompson AM, Quinlan P, Jordan L, Gillett C, Brentnall A, Violette S, Weinreb PH, Kendrew J, Barry ST, Hart IR, Jones JL, Marshall JF.

J Natl Cancer Inst. 2014 Jun 28;106(8). pii: dju169. doi: 10.1093/jnci/dju169. Print 2014 Aug.

12.

Neurological manifestations of influenza infection in children and adults: results of a National British Surveillance Study.

Goenka A, Michael BD, Ledger E, Hart IJ, Absoud M, Chow G, Lilleker J, Lunn M, McKee D, Peake D, Pysden K, Roberts M, Carrol ED, Lim M, Avula S, Solomon T, Kneen R.

Clin Infect Dis. 2014 Mar;58(6):775-84. doi: 10.1093/cid/cit922. Epub 2013 Dec 18.

PMID:
24352349
13.

RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells.

Li NF, Gemenetzidis E, Marshall FJ, Davies D, Yu Y, Frese K, Froeling FE, Woolf AK, Feakins RM, Naito Y, Iacobuzio-Donahue C, Tuveson DA, Hart IR, Kocher HM.

PLoS One. 2013 Dec 3;8(12):e81575. doi: 10.1371/journal.pone.0081575. eCollection 2013.

14.

Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing.

Robbez-Masson LJ, Bödör C, Jones JL, Hurst HC, Fitzgibbon J, Hart IR, Grose RP.

PLoS One. 2013 Nov 12;8(11):e78839. doi: 10.1371/journal.pone.0078839. eCollection 2013.

15.

Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence.

Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA, Dickinson S, Edwards DR, Pennington CJ, Sestak I, Cuzick J, Marshall JF, Hart IR, Jones JL.

Clin Cancer Res. 2014 Jan 15;20(2):344-57. doi: 10.1158/1078-0432.CCR-13-1504. Epub 2013 Oct 22.

16.

Common and new acyclovir resistant herpes simplex virus-1 mutants causing bilateral recurrent herpetic keratitis in an immunocompetent patient.

Pan D, Kaye SB, Hopkins M, Kirwan R, Hart IJ, Coen DM.

J Infect Dis. 2014 Feb 1;209(3):345-9. doi: 10.1093/infdis/jit437. Epub 2013 Aug 14.

17.

FAK-heterozygous mice display enhanced tumour angiogenesis.

Kostourou V, Lechertier T, Reynolds LE, Lees DM, Baker M, Jones DT, Tavora B, Ramjaun AR, Birdsey GM, Robinson SD, Parsons M, Randi AM, Hart IR, Hodivala-Dilke K.

Nat Commun. 2013;4:2020. doi: 10.1038/ncomms3020.

18.

Plasma obestatin and autonomic function are altered in orexin-deficient narcolepsy, but ghrelin is unchanged.

Huda MS, Mani H, Durham BH, Dovey TM, Halford JC, Aditya BS, Pinkney JH, Wilding JP, Hart IK.

Endocrine. 2013 Jun;43(3):696-704. doi: 10.1007/s12020-012-9838-1. Epub 2012 Nov 23.

PMID:
23179778
19.

Detection of herpes viruses in the cerebrospinal fluid of adults with suspected viral meningitis in Malawi.

Benjamin LA, Kelly M, Cohen D, Neuhann F, Galbraith S, Mallewa M, Hopkins M, Hart IJ, Guiver M, Lalloo DG, Heyderman RS, Solomon T.

Infection. 2013 Feb;41(1):27-31. doi: 10.1007/s15010-012-0292-z. Epub 2012 Jul 14.

20.

Combined fiber modifications both to target α(v)β(6) and detarget the coxsackievirus-adenovirus receptor improve virus toxicity profiles in vivo but fail to improve antitumoral efficacy relative to adenovirus serotype 5.

Coughlan L, Vallath S, Gros A, Giménez-Alejandre M, Van Rooijen N, Thomas GJ, Baker AH, Cascalló M, Alemany R, Hart IR.

Hum Gene Ther. 2012 Sep;23(9):960-79. doi: 10.1089/hum.2011.218. Epub 2012 Aug 27.

PMID:
22708837
21.

Improving the diagnosis of central nervous system infections in adults through introduction of a simple lumbar puncture pack.

Michael BD, Powell G, Curtis S, Bailey L, Almond S, McGill F, Cousins D, Hart IJ, Griffiths M, Kneen R, Solomon T.

Emerg Med J. 2013 May;30(5):402-5. doi: 10.1136/emermed-2012-201248. Epub 2012 Jun 15.

PMID:
22707473
23.

β3-integrin is required for differentiation in OC-2 cells derived from mammalian embryonic inner ear.

Brunetta I, Casalotti SO, Hart IR, Forge A, Reynolds LE.

BMC Cell Biol. 2012 Mar 17;13:5. doi: 10.1186/1471-2121-13-5.

24.

Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris.

Tsang SM, Brown L, Lin K, Liu L, Piper K, O'Toole EA, Grose R, Hart IR, Garrod DR, Fortune F, Wan H.

J Pathol. 2012 May;227(1):81-93. doi: 10.1002/path.3982. Epub 2012 Feb 17.

PMID:
22294297
25.

Management of suspected viral encephalitis in adults--Association of British Neurologists and British Infection Association National Guidelines.

Solomon T, Michael BD, Smith PE, Sanderson F, Davies NW, Hart IJ, Holland M, Easton A, Buckley C, Kneen R, Beeching NJ; National Encephalitis Guidelines Development and Stakeholder Groups.

J Infect. 2012 Apr;64(4):347-73. doi: 10.1016/j.jinf.2011.11.014. Epub 2011 Nov 18.

PMID:
22120595
26.

Proteome of formalin-fixed paraffin-embedded pancreatic ductal adenocarcinoma and lymph node metastases.

Naidoo K, Jones R, Dmitrovic B, Wijesuriya N, Kocher H, Hart IR, Crnogorac-Jurcevic T.

J Pathol. 2012 Apr;226(5):756-63. doi: 10.1002/path.3959. Epub 2012 Jan 17. Erratum in: J Pathol. 2012 Aug;227(4):e8.

PMID:
22081483
27.

Eating for two: how stromal fibroblasts might nurture adjacent carcinoma cells.

Hart I.

Cell Cycle. 2011 Sep 1;10(17):2829-30. Epub 2011 Sep 1. No abstract available.

PMID:
21869598
28.

Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression.

Froeling FE, Feig C, Chelala C, Dobson R, Mein CE, Tuveson DA, Clevers H, Hart IR, Kocher HM.

Gastroenterology. 2011 Oct;141(4):1486-97, 1497.e1-14. doi: 10.1053/j.gastro.2011.06.047. Epub 2011 Jun 24.

PMID:
21704588
29.

A direct role for Met endocytosis in tumorigenesis.

Joffre C, Barrow R, Ménard L, Calleja V, Hart IR, Kermorgant S.

Nat Cell Biol. 2011 Jun 5;13(7):827-37. doi: 10.1038/ncb2257.

PMID:
21642981
30.

Editorial: Special section on "site-specific metastasis".

Allgayer H, Hart IR.

Int J Cancer. 2011 Jun 1;128(11):2509-10. doi: 10.1002/ijc.26050. No abstract available.

31.

Detection of norovirus infection in the hospital setting using vomit samples.

Kirby A, Ashton L, Hart IJ.

J Clin Virol. 2011 May;51(1):86-7. doi: 10.1016/j.jcv.2011.02.007. Epub 2011 Mar 3. No abstract available.

PMID:
21376659
32.

Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell-surface marker of the basal phenotype that promotes tumour cell invasion.

Allen MD, Vaziri R, Green M, Chelala C, Brentnall AR, Dreger S, Vallath S, Nitch-Smith H, Hayward J, Carpenter R, Holliday DL, Walker RA, Hart IR, Jones JL.

J Pathol. 2011 Apr;223(5):646-58. doi: 10.1002/path.2833. Epub 2011 Feb 21.

PMID:
21341269
33.

Using the full spectral capacity (six channels) of a real-time PCR instrument can simplify diagnostic laboratory screening and typing protocols for pandemic H1N1 influenza.

Hopkins MJ, Moorcroft JF, Correia JB, Hart IJ.

Influenza Other Respir Viruses. 2011 Mar;5(2):110-4. doi: 10.1111/j.1750-2659.2010.00178.x. Epub 2010 Oct 8.

34.

Stromal features are predictive of disease mortality in oral cancer patients.

Marsh D, Suchak K, Moutasim KA, Vallath S, Hopper C, Jerjes W, Upile T, Kalavrezos N, Violette SM, Weinreb PH, Chester KA, Chana JS, Marshall JF, Hart IR, Hackshaw AK, Piper K, Thomas GJ.

J Pathol. 2011 Mar;223(4):470-81. doi: 10.1002/path.2830. Epub 2011 Jan 5.

PMID:
21294121
35.

Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis.

Moutasim KA, Jenei V, Sapienza K, Marsh D, Weinreb PH, Violette SM, Lewis MP, Marshall JF, Fortune F, Tilakaratne WM, Hart IR, Thomas GJ.

J Pathol. 2011 Feb;223(3):366-77. doi: 10.1002/path.2786. Epub 2010 Oct 25.

PMID:
21171082
36.

Endothelial FAK is required for tumour angiogenesis.

Tavora B, Batista S, Reynolds LE, Jadeja S, Robinson S, Kostourou V, Hart I, Fruttiger M, Parsons M, Hodivala-Dilke KM.

EMBO Mol Med. 2010 Dec;2(12):516-28. doi: 10.1002/emmm.201000106. Erratum in: EMBO Mol Med. 2016 Oct 4;8(10 ):1229.

37.

Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src.

Tsang SM, Liu L, Teh MT, Wheeler A, Grose R, Hart IR, Garrod DR, Fortune F, Wan H.

PLoS One. 2010 Dec 3;5(12):e14211. doi: 10.1371/journal.pone.0014211.

38.

Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion.

Morgan MR, Jazayeri M, Ramsay AG, Thomas GJ, Boulanger MJ, Hart IR, Marshall JF.

Oncogene. 2011 Mar 24;30(12):1422-35. doi: 10.1038/onc.2010.535. Epub 2010 Dec 6.

PMID:
21132011
39.

Validated scales to assess adult decisional balance to eat more fruits and vegetables.

Mainvil LA, Lawson R, Horwath CC, McKenzie JE, Hart I.

Appetite. 2010 Dec;55(3):454-65. doi: 10.1016/j.appet.2010.08.007. Epub 2010 Aug 21.

PMID:
20732362
40.

An effective immunotherapy regimen for VGKC antibody-positive limbic encephalitis.

Wong SH, Saunders MD, Larner AJ, Das K, Hart IK.

J Neurol Neurosurg Psychiatry. 2010 Oct;81(10):1167-9. doi: 10.1136/jnnp.2009.178293. Epub 2010 Jul 26.

PMID:
20660916
41.

Acute central nervous system infections in adults--a retrospective cohort study in the NHS North West region.

Michael BD, Sidhu M, Stoeter D, Roberts M, Beeching NJ, Bonington A, Hart IJ, Kneen R, Miller A, Solomon T; North West Neurological Infections Network.

QJM. 2010 Oct;103(10):749-58. doi: 10.1093/qjmed/hcq121. Epub 2010 Jul 24.

PMID:
20657024
42.

Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF.

da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V, Germain MA, Reynolds AR, Jones DT, Watson AR, Jones JL, Harris A, Hart IR, Iruela-Arispe ML, Dipersio CM, Kreidberg JA, Hodivala-Dilke KM.

Am J Pathol. 2010 Sep;177(3):1534-48. doi: 10.2353/ajpath.2010.100043. Epub 2010 Jul 16.

43.

High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin alphavbeta6.

Saha A, Ellison D, Thomas GJ, Vallath S, Mather SJ, Hart IR, Marshall JF.

J Pathol. 2010 Sep;222(1):52-63. doi: 10.1002/path.2745.

PMID:
20629113
44.

Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome.

Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S, Rodriguez-Manzaneque JC, Martino-Echarri E, Aurrand-Lions M, Sheer D, Dagna-Bricarelli F, Nizetic D, McCabe CJ, Turnell AS, Kermorgant S, Imhof BA, Adams R, Fisher EM, Tybulewicz VL, Hart IR, Hodivala-Dilke KM.

Nature. 2010 Jun 10;465(7299):813-7. doi: 10.1038/nature09106. Erratum in: Nature. 2010 Jul 15;466(7304):398.

45.

Validation of a laboratory-developed real-time PCR protocol for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine.

Hopkins MJ, Ashton LJ, Alloba F, Alawattegama A, Hart IJ.

Sex Transm Infect. 2010 Jun;86(3):207-11. doi: 10.1136/sti.2009.040634.

PMID:
20522633
46.

Favourable one-year ART outcomes in adult Malawians with hepatitis B and C co-infection.

Moore E, Beadsworth MB, Chaponda M, Mhango B, Faragher B, Njala J, Hofland HW, Davies J, Hart IJ, Beeching NJ, Zijlstra EE, van Oosterhout JJ.

J Infect. 2010 Jul;61(2):155-63. doi: 10.1016/j.jinf.2010.04.009. Epub 2010 May 12.

PMID:
20470823
47.

Reliability of rapid testing for hepatitis B in a region of high HIV endemicity.

Davies J, van Oosterhout JJ, Nyirenda M, Bowden J, Moore E, Hart IJ, Zijlstra EE, Chaponda M, Faragher B, Beeching NJ, Beadsworth MB.

Trans R Soc Trop Med Hyg. 2010 Feb;104(2):162-4. doi: 10.1016/j.trstmh.2009.10.010.

PMID:
19931107
48.

Human herpesvirus 6 infection after solid organ transplantation.

Bakran A, Hart IJ.

Transplantation. 2009 Sep 27;88(6):757-8. doi: 10.1097/TP.0b013e3181b4452b. No abstract available.

PMID:
19920771
49.

New evidence for tumour embolism as a mode of metastasis.

Hart IR.

J Pathol. 2009 Nov;219(3):275-6. doi: 10.1002/path.2616.

PMID:
19768739
50.

Loss-of-function FERMT1 mutations in kindler syndrome implicate a role for fermitin family homolog-1 in integrin activation.

Lai-Cheong JE, Parsons M, Tanaka A, Ussar S, South AP, Gomathy S, Mee JB, Barbaroux JB, Techanukul T, Almaani N, Clements SE, Hart IR, McGrath JA.

Am J Pathol. 2009 Oct;175(4):1431-41. doi: 10.2353/ajpath.2009.081154. Epub 2009 Sep 17.

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