Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 235

1.

Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase.

Lazo JS, Blanco IK, Tasker NR, Rastelli EJ, Burnett JC, Garrott SR, Hart DJ, McCloud RL, Hsu KL, Wipf P, Sharlow ER.

J Pharmacol Exp Ther. 2019 Dec;371(3):652-662. doi: 10.1124/jpet.119.262188. Epub 2019 Oct 10.

PMID:
31601683
2.

TwinsUK: The UK Adult Twin Registry Update.

Verdi S, Abbasian G, Bowyer RCE, Lachance G, Yarand D, Christofidou P, Mangino M, Menni C, Bell JT, Falchi M, Small KS, Williams FMK, Hammond CJ, Hart DJ, Spector TD, Steves CJ.

Twin Res Hum Genet. 2019 Sep 17:1-7. doi: 10.1017/thg.2019.65. [Epub ahead of print]

PMID:
31526404
3.

A Simple Method for Simulating Groundwater Interactions with Fens to Forecast Development Effects.

Feinstein DT, Hart DJ, Gatzke S, Hunt RJ, Niswonger RG, Fienen MN.

Ground Water. 2019 Jul 30. doi: 10.1111/gwat.12931. [Epub ahead of print]

PMID:
31364162
4.
5.

Auxin sensing is a property of an unstructured domain in the Auxin Response Factor ETTIN of Arabidopsis thaliana.

Simonini S, Mas PJ, Mas CMVS, Østergaard L, Hart DJ.

Sci Rep. 2018 Sep 10;8(1):13563. doi: 10.1038/s41598-018-31634-9.

6.

Association of metabolic syndrome with knee and hand osteoarthritis: A community-based study of women.

Sanchez-Santos MT, Judge A, Gulati M, Spector TD, Hart DJ, Newton JL, Arden NK, Kluzek S.

Semin Arthritis Rheum. 2019 Apr;48(5):791-798. doi: 10.1016/j.semarthrit.2018.07.007. Epub 2018 Jul 31.

PMID:
30172470
7.

Three Novel Escherichia coli Vectors for Convenient and Efficient Molecular Biological Manipulations.

Gao H, Qi X, Hart DJ, Gao S, Wang H, Xu S, Zhang Y, Liu X, Liu Y, An Y.

J Agric Food Chem. 2018 Jun 20;66(24):6123-6131. doi: 10.1021/acs.jafc.8b01960. Epub 2018 Jun 11.

PMID:
29798665
8.

A universal mini-vector and an annealing of PCR products (APP)-based cloning strategy for convenient molecular biological manipulations.

Liu X, Li T, Hart DJ, Gao S, Wang H, Gao H, Xu S, Zhang Y, Liu Y, An Y.

Biochem Biophys Res Commun. 2018 Mar 18;497(4):978-982. doi: 10.1016/j.bbrc.2018.02.099. Epub 2018 Feb 12.

PMID:
29448102
9.

The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.

Tarbouriech N, Ducournau C, Hutin S, Mas PJ, Man P, Forest E, Hart DJ, Peyrefitte CN, Burmeister WP, Iseni F.

Nat Commun. 2017 Nov 13;8(1):1455. doi: 10.1038/s41467-017-01542-z.

10.

Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.

den Hollander W, Boer CG, Hart DJ, Yau MS, Ramos YFM, Metrustry S, Broer L, Deelen J, Cupples LA, Rivadeneira F, Kloppenburg M, Peters M, Spector TD, Hofman A, Slagboom PE, Nelissen RGHH, Uitterlinden AG, Felson DT, Valdes AM, Meulenbelt I, van Meurs JJB.

Ann Rheum Dis. 2017 Dec;76(12):2046-2053. doi: 10.1136/annrheumdis-2017-211214. Epub 2017 Aug 30.

11.

Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7.

Desravines DC, Serna Martin I, Schneider R, Mas PJ, Aleksandrova N, Jensen MR, Blackledge M, Hart DJ.

Sci Rep. 2017 Jun 16;7(1):3678. doi: 10.1038/s41598-017-03718-5.

12.

Serum Lipid Levels and Risk Of Hand Osteoarthritis: The Chingford Prospective Cohort Study.

Garcia-Gil M, Reyes C, Ramos R, Sanchez-Santos MT, Prieto-Alhambra D, Spector TD, Hart DJ, Arden NK.

Sci Rep. 2017 Jun 9;7(1):3147. doi: 10.1038/s41598-017-03317-4.

13.

Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1).

Sukackaite R, Cornacchia D, Jensen MR, Mas PJ, Blackledge M, Enervald E, Duan G, Auchynnikava T, Köhn M, Hart DJ, Buonomo SBC.

Sci Rep. 2017 May 18;7(1):2119. doi: 10.1038/s41598-017-01910-1.

14.

Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene.

Warner SC, Walsh DA, Laslett LL, Maciewicz RA, Soni A, Hart DJ, Zhang W, Muir KR, Dennison EM, Leaverton P, Rampersaud E, Cooper C, Spector TD, Cicuttini FM, Arden NK, Jones G, Doherty M, Valdes AM.

Eur J Pain. 2017 Aug;21(7):1277-1284. doi: 10.1002/ejp.1027. Epub 2017 May 11.

15.

ESPRIT: A Method for Defining Soluble Expression Constructs in Poorly Understood Gene Sequences.

Mas PJ, Hart DJ.

Methods Mol Biol. 2017;1586:45-63. doi: 10.1007/978-1-4939-6887-9_4.

PMID:
28470598
16.

Structural insights into the architecture of the Shigella flexneri virulence factor IcsA/VirG and motifs involved in polar distribution and secretion.

Leupold S, Büsing P, Mas PJ, Hart DJ, Scrima A.

J Struct Biol. 2017 Apr;198(1):19-27. doi: 10.1016/j.jsb.2017.03.003. Epub 2017 Mar 6.

PMID:
28268178
17.

A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations.

Yerabham ASK, Mas PJ, Decker C, Soares DC, Weiergräber OH, Nagel-Steger L, Willbold D, Hart DJ, Bradshaw NJ, Korth C.

J Biol Chem. 2017 Apr 21;292(16):6468-6477. doi: 10.1074/jbc.M116.773903. Epub 2017 Mar 1.

18.

Expression and Characterization of Levansucrase from Clostridium acetobutylicum.

Gao S, Qi X, Hart DJ, Gao H, An Y.

J Agric Food Chem. 2017 Feb 1;65(4):867-871. doi: 10.1021/acs.jafc.6b05165. Epub 2017 Jan 18.

PMID:
28075130
19.

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.

Castaño-Betancourt MC, Evans DS, Ramos YF, Boer CG, Metrustry S, Liu Y, den Hollander W, van Rooij J, Kraus VB, Yau MS, Mitchell BD, Muir K, Hofman A, Doherty M, Doherty S, Zhang W, Kraaij R, Rivadeneira F, Barrett-Connor E, Maciewicz RA, Arden N, Nelissen RG, Kloppenburg M, Jordan JM, Nevitt MC, Slagboom EP, Hart DJ, Lafeber F, Styrkarsdottir U, Zeggini E, Evangelou E, Spector TD, Uitterlinden AG, Lane NE, Meulenbelt I, Valdes AM, van Meurs JB.

PLoS Genet. 2016 Oct 4;12(10):e1006260. doi: 10.1371/journal.pgen.1006260. eCollection 2016 Oct.

20.

Investigating the Role of Large-Scale Domain Dynamics in Protein-Protein Interactions.

Delaforge E, Milles S, Huang JR, Bouvier D, Jensen MR, Sattler M, Hart DJ, Blackledge M.

Front Mol Biosci. 2016 Sep 13;3:54. doi: 10.3389/fmolb.2016.00054. eCollection 2016. Review.

21.

Recent advances in universal TA cloning methods for use in function studies.

Yao S, Hart DJ, An Y.

Protein Eng Des Sel. 2016 Nov 1;29(11):551-556. doi: 10.1093/protein/gzw047.

PMID:
27578885
22.

Symptoms of Raynaud's phenomenon (RP) in fibromyalgia syndrome are similar to those reported in primary RP despite differences in objective assessment of digital microvascular function and morphology.

Scolnik M, Vasta B, Hart DJ, Shipley JA, McHugh NJ, Pauling JD.

Rheumatol Int. 2016 Oct;36(10):1371-7. doi: 10.1007/s00296-016-3483-6. Epub 2016 May 2.

23.

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites.

Simon B, Huart AS, Temmerman K, Vahokoski J, Mertens HD, Komadina D, Hoffmann JE, Yumerefendi H, Svergun DI, Kursula P, Schultz C, McCarthy AA, Hart DJ, Wilmanns M.

Structure. 2016 Jun 7;24(6):851-61. doi: 10.1016/j.str.2016.03.020. Epub 2016 Apr 28.

24.

Aging Trajectories in Different Body Systems Share Common Environmental Etiology: The Healthy Aging Twin Study (HATS).

Moayyeri A, Hart DJ, Snieder H, Hammond CJ, Spector TD, Steves CJ.

Twin Res Hum Genet. 2016 Feb;19(1):27-34. doi: 10.1017/thg.2015.100.

PMID:
26810865
25.

Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.

Thierry E, Guilligay D, Kosinski J, Bock T, Gaudon S, Round A, Pflug A, Hengrung N, El Omari K, Baudin F, Hart DJ, Beck M, Cusack S.

Mol Cell. 2016 Jan 7;61(1):125-37. doi: 10.1016/j.molcel.2015.11.016. Epub 2015 Dec 17.

26.

A comparison of radiographic anatomic axis knee alignment measurements and cross-sectional associations with knee osteoarthritis.

Goulston LM, Sanchez-Santos MT, D'Angelo S, Leyland KM, Hart DJ, Spector TD, Cooper C, Dennison EM, Hunter D, Arden NK.

Osteoarthritis Cartilage. 2016 Apr;24(4):612-22. doi: 10.1016/j.joca.2015.11.009. Epub 2015 Dec 14.

27.

Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin α.

Delaforge E, Milles S, Bouvignies G, Bouvier D, Boivin S, Salvi N, Maurin D, Martel A, Round A, Lemke EA, Jensen MR, Hart DJ, Blackledge M.

J Am Chem Soc. 2015 Dec 9;137(48):15122-34. doi: 10.1021/jacs.5b07765. Epub 2015 Oct 16.

PMID:
26424125
28.

Use of Laser Speckle Contrast Imaging to Assess Digital Microvascular Function in Primary Raynaud Phenomenon and Systemic Sclerosis: A Comparison Using the Raynaud Condition Score Diary.

Pauling JD, Shipley JA, Hart DJ, McGrogan A, McHugh NJ.

J Rheumatol. 2015 Jul;42(7):1163-8. doi: 10.3899/jrheum.141437. Epub 2015 Jun 1.

PMID:
26034146
29.

Vascular disease of the spine.

Munyon CN, Hart DJ.

Neurologist. 2015 May;19(5):121-7. doi: 10.1097/NRL.0000000000000018. Review.

PMID:
25970833
30.

Complications in Surgical Treatment of Cervical Spondylotic Myelopathy: What We Think We Know.

Shammassian B, Hart DJ.

World Neurosurg. 2015 Sep;84(3):627-9. doi: 10.1016/j.wneu.2015.04.016. Epub 2015 Apr 15. No abstract available.

PMID:
25888812
31.

Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7.

Pumroy RA, Ke S, Hart DJ, Zachariae U, Cingolani G.

Structure. 2015 Feb 3;23(2):374-84. doi: 10.1016/j.str.2014.11.015. Epub 2015 Jan 15.

32.

Individuals with high bone mass have an increased prevalence of radiographic knee osteoarthritis.

Hardcastle SA, Dieppe P, Gregson CL, Arden NK, Spector TD, Hart DJ, Edwards MH, Dennison EM, Cooper C, Sayers A, Williams M, Davey Smith G, Tobias JH.

Bone. 2015 Feb;71:171-9. doi: 10.1016/j.bone.2014.10.015. Epub 2014 Oct 30.

33.

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.

Ramos YF, Metrustry S, Arden N, Bay-Jensen AC, Beekman M, de Craen AJ, Cupples LA, Esko T, Evangelou E, Felson DT, Hart DJ, Ioannidis JP, Karsdal M, Kloppenburg M, Lafeber F, Metspalu A, Panoutsopoulou K, Slagboom PE, Spector TD, van Spil EW, Uitterlinden AG, Zhu Y; arcOGEN Consortium; TreatOA Collaborators, Valdes AM, van Meurs JB, Meulenbelt I.

J Med Genet. 2014 Sep;51(9):596-604. doi: 10.1136/jmedgenet-2014-102478. Epub 2014 Jul 23.

PMID:
25057126
34.

Association of interleukin-6 gene polymorphisms with hand osteoarthritis and hand osteoporosis.

Blumenfeld O, Williams FM, Valdes A, Hart DJ, Malkin I, Spector TD, Livshits G.

Cytokine. 2014 Sep;69(1):94-101. doi: 10.1016/j.cyto.2014.05.012. Epub 2014 Jun 11.

PMID:
25022967
35.

Prevalence of radiographic hip osteoarthritis is increased in high bone mass.

Hardcastle SA, Dieppe P, Gregson CL, Hunter D, Thomas GE, Arden NK, Spector TD, Hart DJ, Laugharne MJ, Clague GA, Edwards MH, Dennison EM, Cooper C, Williams M, Davey Smith G, Tobias JH.

Osteoarthritis Cartilage. 2014 Aug;22(8):1120-8. doi: 10.1016/j.joca.2014.06.007. Epub 2014 Jun 24.

36.

Osteophytes, enthesophytes, and high bone mass: a bone-forming triad with potential relevance in osteoarthritis.

Hardcastle SA, Dieppe P, Gregson CL, Arden NK, Spector TD, Hart DJ, Edwards MH, Dennison EM, Cooper C, Williams M, Davey Smith G, Tobias JH.

Arthritis Rheumatol. 2014 Sep;66(9):2429-39. doi: 10.1002/art.38729.

37.

Structural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures.

Sukackaite R, Jensen MR, Mas PJ, Blackledge M, Buonomo SB, Hart DJ.

J Biol Chem. 2014 May 16;289(20):13903-11. doi: 10.1074/jbc.M114.557843. Epub 2014 Mar 14.

38.

A drag reducing surfactant threadlike micelle system with unusual rheological responses to pH.

Shi H, Ge W, Wang Y, Fang B, Huggins JT, Russell TA, Talmon Y, Hart DJ, Zakin JL.

J Colloid Interface Sci. 2014 Mar 15;418:95-102. doi: 10.1016/j.jcis.2013.11.078. Epub 2013 Dec 8.

PMID:
24461823
39.

Traumatic, high-cervical, coronal-plane spondyloptosis with unilateral vertebral artery occlusion: treatment using a prophylactic arterial bypass graft, open reduction, and instrumented segmental fusion.

Manjila S, Chowdhry SA, Bambakidis NC, Hart DJ.

J Neurosurg Spine. 2014 Feb;20(2):183-90. doi: 10.3171/2013.10.SPINE13115. Epub 2013 Nov 29.

PMID:
24286529
40.

Advanced imaging techniques in cervical spinal cord trauma.

Alonso F, Hart DJ.

World Neurosurg. 2015 Apr;83(4):496-7. doi: 10.1016/j.wneu.2013.10.059. Epub 2013 Oct 29. No abstract available.

PMID:
24176838
41.

Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors.

Kerkhof HJ, Bierma-Zeinstra SM, Arden NK, Metrustry S, Castano-Betancourt M, Hart DJ, Hofman A, Rivadeneira F, Oei EH, Spector TD, Uitterlinden AG, Janssens AC, Valdes AM, van Meurs JB.

Ann Rheum Dis. 2014 Dec;73(12):2116-21. doi: 10.1136/annrheumdis-2013-203620. Epub 2013 Aug 20.

PMID:
23962456
42.

The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study.

Panoutsopoulou K, Metrustry S, Doherty SA, Laslett LL, Maciewicz RA, Hart DJ, Zhang W, Muir KR, Wheeler M, Cooper C, Spector TD, Cicuttini FM, Jones G, Arden NK, Doherty M, Zeggini E, Valdes AM; arcOGEN Consortium.

Ann Rheum Dis. 2014 Dec;73(12):2082-6. doi: 10.1136/annrheumdis-2013-203772. Epub 2013 Aug 6.

43.

Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis.

Neogi T, Soni A, Doherty SA, Laslett LL, Maciewicz RA, Hart DJ, Zhang W, Muir KR, Wheeler M, Cooper C, Spector TD, Cicuttini F, Jones G, Nevitt M, Liu Y, Arden NK, Doherty M, Valdes AM.

Ann Rheum Dis. 2014 Jan;73(1):315-7. doi: 10.1136/annrheumdis-2013-203836. Epub 2013 Jul 13. No abstract available.

44.

Bioavailability of epicatechin and effects on nitric oxide metabolites of an apple flavanol-rich extract supplemented beverage compared to a whole apple puree: a randomized, placebo-controlled, crossover trial.

Hollands WJ, Hart DJ, Dainty JR, Hasselwander O, Tiihonen K, Wood R, Kroon PA.

Mol Nutr Food Res. 2013 Jul;57(7):1209-17. doi: 10.1002/mnfr.201200663. Epub 2013 Apr 23.

PMID:
23610075
45.

Library methods for structural biology of challenging proteins and their complexes.

Hart DJ, Waldo GS.

Curr Opin Struct Biol. 2013 Jun;23(3):403-8. doi: 10.1016/j.sbi.2013.03.004. Epub 2013 Apr 17. Review.

46.

Association between cartilage and bone biomarkers and incidence of radiographic knee osteoarthritis (RKOA) in UK females: a prospective study.

Blumenfeld O, Williams FM, Hart DJ, Spector TD, Arden N, Livshits G.

Osteoarthritis Cartilage. 2013 Jul;21(7):923-9. doi: 10.1016/j.joca.2013.04.009. Epub 2013 Apr 15.

47.

Neuropathic features of joint pain: a community-based study.

Soni A, Batra RN, Gwilym SE, Spector TD, Hart DJ, Arden NK, Cooper C, Tracey I, Javaid MK.

Arthritis Rheum. 2013 Jul;65(7):1942-9. doi: 10.1002/art.37962.

48.

Photoreversible micellar solution as a smart drag-reducing fluid for use in district heating/cooling systems.

Shi H, Ge W, Oh H, Pattison SM, Huggins JT, Talmon Y, Hart DJ, Raghavan SR, Zakin JL.

Langmuir. 2013 Jan 8;29(1):102-9. doi: 10.1021/la304001r. Epub 2012 Dec 19.

PMID:
23210742
49.

Minimally invasive presacral retrieval of a failed AxiaLIF rod implant: technical note and illustrative cases.

Manjila S, Singer J, Knudson K, Tomac AC, Hart DJ.

Spine J. 2012 Oct;12(10):940-8. doi: 10.1016/j.spinee.2012.10.026.

PMID:
23199822
50.

Toward clarity of management options in spinal synovial cysts.

Carmody M, Hart DJ.

World Neurosurg. 2013 Feb;79(2):283-4. doi: 10.1016/j.wneu.2012.10.046. Epub 2012 Oct 27. No abstract available.

PMID:
23111222

Supplemental Content

Support Center