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Items: 1 to 50 of 474

1.

Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice.

Smith BJ, Miller RA, Ericsson AC, Harrison DC, Strong R, Schmidt TM.

BMC Microbiol. 2019 Jun 13;19(1):130. doi: 10.1186/s12866-019-1494-7.

2.

The Björk-Shiley convexo-concave heart valve experience from the perspective of the supervisory panel. Reply.

Harrison DC.

Am J Cardiol. 2014 Jun 15;113(12):2089-90. doi: 10.1016/j.amjcard.2014.03.030. Epub 2014 Mar 28. No abstract available.

PMID:
24878137
3.

The Björk-Shiley convexo-concave heart valve experience from the perspective of the supervisory panel.

Harrison DC, Ibrahim MA, Weyman AE, Kuller LH, Blot WJ, Miller DE.

Am J Cardiol. 2013 Dec 15;112(12):1921-31. doi: 10.1016/j.amjcard.2013.08.020. Epub 2013 Sep 21.

PMID:
24063829
4.

Orally bioavailable and brain-penetrant pyridazine and pyridine-derived γ-secretase modulators reduced amyloidogenic Aβ peptides in vivo.

Huang Y, Li T, Eatherton A, Mitchell WL, Rong N, Ye L, Yang XJ, Jin S, Ding Y, Zhang J, Li Y, Wu Y, Jin Y, Sang Y, Cheng Z, Browne ER, Harrison DC, Hussain I, Wan Z, Hall A, Lau LF, Matsuoka Y.

Neuropharmacology. 2013 Jul;70:278-86. doi: 10.1016/j.neuropharm.2013.02.003. Epub 2013 Feb 26.

PMID:
23485401
5.

Form and function.

Harrison DC.

CMAJ. 2012 Feb 7;184(2):215. doi: 10.1503/cmaj.112-2014. No abstract available.

6.

Γ-secretase modulators do not induce Aβ-rebound and accumulation of β-C-terminal fragment.

Li T, Huang Y, Jin S, Ye L, Rong N, Yang X, Ding Y, Cheng Z, Zhang J, Wan Z, Harrison DC, Hussain I, Hall A, Lee DH, Lau LF, Matsuoka Y.

J Neurochem. 2012 Apr;121(2):277-86. doi: 10.1111/j.1471-4159.2011.07560.x. Epub 2012 Mar 13.

7.

Pyridine-derived γ-secretase modulators.

Wan Z, Hall A, Sang Y, Xiang JN, Yang E, Smith B, Harrison DC, Yang G, Yu H, Price HS, Wang J, Hawkins J, Lau LF, Johnson MR, Li T, Zhao W, Mitchell WL, Su X, Zhang X, Zhou Y, Jin Y, Tong Z, Cheng Z, Hussain I, Elliott JD, Matsuoka Y.

Bioorg Med Chem Lett. 2011 Aug 15;21(16):4832-5. doi: 10.1016/j.bmcl.2011.06.042. Epub 2011 Jun 17.

PMID:
21742495
8.

Dynamics of Aβ42 reduction in plasma, CSF and brain of rats treated with the γ-secretase modulator, GSM-10h.

Hawkins J, Harrison DC, Ahmed S, Davis RP, Chapman T, Marshall I, Smith B, Mead TL, Medhurst A, Giblin GM, Hall A, Gonzalez MI, Richardson J, Hussain I.

Neurodegener Dis. 2011;8(6):455-64. doi: 10.1159/000324511. Epub 2011 Mar 10.

PMID:
21389687
9.

The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase.

Vasilaki A, van der Meulen JH, Larkin L, Harrison DC, Pearson T, Van Remmen H, Richardson A, Brooks SV, Jackson MJ, McArdle A.

Aging Cell. 2010 Dec;9(6):979-90. doi: 10.1111/j.1474-9726.2010.00635.x. Epub 2010 Oct 29.

10.

TASTPM mice expressing amyloid precursor protein and presenilin-1 mutant transgenes are sensitive to γ-secretase modulation and amyloid-β₄₂ lowering by GSM-10h.

Hussain I, Harrison DC, Hawkins J, Chapman T, Marshall I, Facci L, Ahmed S, Brackenborough K, Skaper SD, Mead TL, Smith BB, Giblin GM, Hall A, Gonzalez MI, Richardson JC.

Neurodegener Dis. 2011;8(1-2):15-24. doi: 10.1159/000313903. Epub 2010 Aug 4.

PMID:
20689247
11.

Donald Carey Harrison, MD: a conversation with the editor. Interview by William Clifford Roberts, MD.

Harrison DC.

Am J Cardiol. 2006 May 1;97(9):1399-421. Epub 2006 Mar 23. No abstract available.

PMID:
16635619
12.

Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin.

Li Y, Zhang D, Jin W, Shao C, Yan P, Xu C, Sheng H, Liu Y, Yu J, Xie Y, Zhao Y, Lu D, Nebert DW, Harrison DC, Huang W, Jin L.

J Clin Invest. 2006 Feb;116(2):506-11. Epub 2006 Jan 26.

13.

Quantitative analysis of gene transcription in stroke models using real-time RT-PCR.

Harrison DC, Bond BC.

Methods Mol Med. 2005;104:265-84.

PMID:
15454673
14.

Localisation of NMU1R and NMU2R in human and rat central nervous system and effects of neuromedin-U following central administration in rats.

Gartlon J, Szekeres P, Pullen M, Sarau HM, Aiyar N, Shabon U, Michalovich D, Steplewski K, Ellis C, Elshourbagy N, Duxon M, Ashmeade TE, Harrison DC, Murdock P, Wilson S, Ennaceur A, Atkins A, Heidbreder C, Hagan JJ, Hunter AJ, Jones DN.

Psychopharmacology (Berl). 2004 Dec;177(1-2):1-14. Epub 2004 Jun 16.

PMID:
15205870
15.
16.

The distribution of the orphan bombesin receptor subtype-3 in the rat CNS.

Jennings CA, Harrison DC, Maycox PR, Crook B, Smart D, Hervieu GJ.

Neuroscience. 2003;120(2):309-24.

PMID:
12890504
17.

Localisation of the GPRC5B receptor in the rat brain and spinal cord.

Robbins MJ, Charles KJ, Harrison DC, Pangalos MN.

Brain Res Mol Brain Res. 2002 Oct 15;106(1-2):136-44.

PMID:
12393273
18.

Increased cortical expression of the orexin-1 receptor following permanent middle cerebral artery occlusion in the rat.

Irving EA, Harrison DC, Babbs AJ, Mayes AC, Campbell CA, Hunter AJ, Upton N, Parsons AA.

Neurosci Lett. 2002 May 10;324(1):53-6.

PMID:
11983293
19.

Protein distribution of the orexin-2 receptor in the rat central nervous system.

Cluderay JE, Harrison DC, Hervieu GJ.

Regul Pept. 2002 Mar 15;104(1-3):131-44.

PMID:
11830288
20.

Selective increases in cytokine expression in the rat brain in response to striatal injection of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and interleukin-1.

Allan SM, Harrison DC, Read S, Collins B, Parsons AA, Philpott K, Rothwell NJ.

Brain Res Mol Brain Res. 2001 Sep 30;93(2):180-9.

PMID:
11589995
21.

Characterisation of gene expression changes following permanent MCAO in the rat using subtractive hybridisation.

Bates S, Read SJ, Harrison DC, Topp S, Morrow R, Gale D, Murdock P, Barone FC, Parsons AA, Gloger IS.

Brain Res Mol Brain Res. 2001 Sep 10;93(1):70-80.

PMID:
11532340
22.

Central effects of urotensin-II following ICV administration in rats.

Gartlon J, Parker F, Harrison DC, Douglas SA, Ashmeade TE, Riley GJ, Hughes ZA, Taylor SG, Munton RP, Hagan JJ, Hunter JA, Jones DN.

Psychopharmacology (Berl). 2001 Jun;155(4):426-33.

PMID:
11441433
23.

Stroke genomics: approaches to identify, validate, and understand ischemic stroke gene expression.

Read SJ, Parsons AA, Harrison DC, Philpott K, Kabnick K, O' Brien S, Clark S, Brawner M, Bates S, Gloger I, Legos JJ, Barone FC.

J Cereb Blood Flow Metab. 2001 Jul;21(7):755-78. Review.

PMID:
11435788
24.

AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1.

Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC.

J Biol Chem. 2001 Aug 3;276(31):28969-75. Epub 2001 May 31.

25.

An unusual case of cavernous sinus syndrome.

Harrison DC, Roberts CJ.

Eye (Lond). 2001 Apr;15(Pt 2):244-5. No abstract available.

PMID:
11339609
26.

Caspase mRNA expression in a rat model of focal cerebral ischemia.

Harrison DC, Davis RP, Bond BC, Campbell CA, James MF, Parsons AA, Philpott KL.

Brain Res Mol Brain Res. 2001 Apr 18;89(1-2):133-46.

PMID:
11311984
27.

Self-reported quality of life and health among Björk-Shiley convexo-concave prosthetic heart valve patients.

Signorello LB, Kennedy JA, Richmond RA, Sieu KL, Blot WJ, Harrison DC.

J Heart Valve Dis. 2001 Mar;10(2):210-8.

PMID:
11297208
28.

Upregulation of death pathway molecules in rat cerebellar granule neurons undergoing apoptosis.

Ginham R, Harrison DC, Facci L, Skaper S, Philpott KL.

Neurosci Lett. 2001 Apr 20;302(2-3):113-6.

PMID:
11290400
29.

Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord.

Hervieu GJ, Cluderay JE, Harrison DC, Roberts JC, Leslie RA.

Neuroscience. 2001;103(3):777-97.

PMID:
11274794
30.

Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia.

Barone FC, Irving EA, Ray AM, Lee JC, Kassis S, Kumar S, Badger AM, Legos JJ, Erhardt JA, Ohlstein EH, Hunter AJ, Harrison DC, Philpott K, Smith BR, Adams JL, Parsons AA.

Med Res Rev. 2001 Mar;21(2):129-45. Review.

PMID:
11223862
31.

Male circumcision and HIV infection.

Harrison DC.

Lancet. 2000 Mar 11;355(9207):926; author reply 927. No abstract available.

PMID:
10752724
32.

Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.

Hayes P, Meadows HJ, Gunthorpe MJ, Harries MH, Duckworth DM, Cairns W, Harrison DC, Clarke CE, Ellington K, Prinjha RK, Barton AJ, Medhurst AD, Smith GD, Topp S, Murdock P, Sanger GJ, Terrett J, Jenkins O, Benham CD, Randall AD, Gloger IS, Davis JB.

Pain. 2000 Nov;88(2):205-15.

PMID:
11050376
33.

The expression of GABA(B1) and GABA(B2) receptor subunits in the cNS differs from that in peripheral tissues.

Calver AR, Medhurst AD, Robbins MJ, Charles KJ, Evans ML, Harrison DC, Stammers M, Hughes SA, Hervieu G, Couve A, Moss SJ, Middlemiss DN, Pangalos MN.

Neuroscience. 2000;100(1):155-70.

PMID:
10996466
34.

The use of TaqMan RT-PCR assays for semiquantitative analysis of gene expression in CNS tissues and disease models.

Medhurst AD, Harrison DC, Read SJ, Campbell CA, Robbins MJ, Pangalos MN.

J Neurosci Methods. 2000 May 15;98(1):9-20.

PMID:
10837866
35.

TR3 death receptor expression in the normal and ischaemic brain.

Harrison DC, Roberts J, Campbell CA, Crook B, Davis R, Deen K, Meakin J, Michalovich D, Price J, Stammers M, Maycox PR.

Neuroscience. 2000;96(1):147-60.

PMID:
10777386
36.

The use of quantitative RT-PCR to measure mRNA expression in a rat model of focal ischemia--caspase-3 as a case study.

Harrison DC, Medhurst AD, Bond BC, Campbell CA, Davis RP, Philpott KL.

Brain Res Mol Brain Res. 2000 Jan 10;75(1):143-9.

PMID:
10648898
37.

Failure of isradipine to reduce infarct size in mouse, gerbil, and rat models of cerebral ischemia.

Bailey SJ, Wood NI, Samson NA, Rothaul AL, Roberts JC, King PD, Hamilton TC, Harrison DC, Hunter AJ.

Stroke. 1995 Nov;26(11):2177-83.

PMID:
7482669
38.

SB 201823-A antagonizes calcium currents in central neurons and reduces the effects of focal ischemia in rats and mice.

Barone FC, Lysko PG, Price WJ, Feuerstein G, al-Baracanji KA, Benham CD, Harrison DC, Harries MH, Bailey SJ, Hunter AJ.

Stroke. 1995 Sep;26(9):1683-9; discussion 1689-90.

PMID:
7660415
39.

Funding for the colleges of medicine: integrated delivery systems to the rescue.

Harrison DC, Hutton JJ, Hillard JR.

Trans Am Clin Climatol Assoc. 1996;107:238-46; discussion 246-8. No abstract available.

40.

Managed care involvement by cardiovascular specialists: prevalence, attitudes and influence on practice.

DeMaria AN, Engle MA, Harrison DC, Judge RD, Kouchoukos NT, Lee TH, Mills PS, Ganslaw LS, Seidman JJ.

J Am Coll Cardiol. 1994 Apr;23(5):1245-53.

41.

Dynamic gadolinium-enhanced three-dimensional abdominal MR arteriography.

Prince MR, Yucel EK, Kaufman JA, Harrison DC, Geller SC.

J Magn Reson Imaging. 1993 Nov-Dec;3(6):877-81.

PMID:
8280977
42.

The Sicilian Gambit: reasons for maintaining the present antiarrhythmic drug classification.

Harrison DC.

Cardiovasc Res. 1992 Jun;26(6):566-7. Review. No abstract available.

PMID:
1451134
43.

Ethics in health economics.

Harrison DC.

Pharmacoeconomics. 1992 Feb;1(2):147-8. No abstract available.

PMID:
10147107
44.

Advances in antiarrhythmic drug therapy.

Harrison DC, Bottorff MB.

Adv Pharmacol. 1992;23:179-225. Review. No abstract available.

PMID:
1540535
45.

Plaque-associated immune reactivity as a tool for the diagnosis and treatment of atherosclerosis.

Harrison DC, Calenoff E, Chen FW, Parmley WW, Khaw BA, Ross R.

Trans Am Clin Climatol Assoc. 1992;103:210-7.

46.

A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes.

Harrison DC, Lemasters JJ, Herman B.

Biochem Biophys Res Commun. 1991 Jan 31;174(2):654-9.

PMID:
1899571
47.

Histamine mediates myocardial damage by an H1 mechanism independent of coronary blood flow.

Kantrowitz NE, Ellis AK, Bristow MR, Minobe W, Billingham ME, Harrison DC.

J Cardiovasc Pharmacol. 1990 Jan;15(1):82-8.

PMID:
1688987
48.

Radiologic diagnosis of absent left lobe of the liver.

Banerjee B, Harrison DC.

AJR Am J Roentgenol. 1989 Apr;152(4):894-5. No abstract available.

PMID:
2784275
49.

Arrhythmia prophylaxis after acute myocardial infarction: a decade of controversy.

Harrison DC.

Cardiovasc Drugs Ther. 1989 Jan;2(6):783-9. Review.

PMID:
2488092
50.

The hemodynamic effects of repeated bed rest exposure.

Sandler H, Popp RL, Harrison DC.

Aviat Space Environ Med. 1988 Nov;59(11 Pt 1):1047-54.

PMID:
3202785

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