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Variation between hospitals in outcomes following cardiac surgery in the UK.

Soppa G, Theodoropoulos P, Bilkhu R, Harrison DA, Alam R, Beattie R, Bleetman D, Hussain A, Jones S, Kenny L, Khorsandi M, Lea A, Mensah K, Hici TN, Pinho-Gomes AC, Rogers L, Sepehripour A, Singh S, Steele D, Weaver H, Klein A, Fletcher N, Jahangiri M.

Ann R Coll Surg Engl. 2019 Mar 11:1-9. doi: 10.1308/rcsann.2019.0029. [Epub ahead of print]


Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: a multicentre randomized clinical pilot trial.

Peters MJ, Woolfall K, Khan I, Deja E, Mouncey PR, Wulff J, Mason A, Agbeko RS, Draper ES, Fenn B, Gould DW, Koelewyn A, Klein N, Mackerness C, Martin S, O'Neill L, Ray S, Ramnarayan P, Tibby S, Thorburn K, Tume L, Watkins J, Wellman P, Harrison DA, Rowan KM; FEVER Investigators on behalf of the Paediatric Intensive Care Society Study Group (PICS-SG).

Crit Care. 2019 Mar 7;23(1):69. doi: 10.1186/s13054-019-2354-4.


Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT.

Peters MJ, Khan I, Woolfall K, Deja E, Mouncey PR, Wulff J, Mason A, Agbeko R, Draper ES, Fenn B, Gould DW, Koelewyn A, Klein N, Mackerness C, Martin S, O'Neill L, Ramnarayan P, Tibby S, Tume L, Watkins J, Thorburn K, Wellman P, Harrison DA, Rowan KM.

Health Technol Assess. 2019 Feb;23(5):1-148. doi: 10.3310/hta23050.


Effect of a Nurse-Led Preventive Psychological Intervention on Symptoms of Posttraumatic Stress Disorder Among Critically Ill Patients: A Randomized Clinical Trial.

Wade DM, Mouncey PR, Richards-Belle A, Wulff J, Harrison DA, Sadique MZ, Grieve RD, Emerson LM, Mason AJ, Aaronovitch D, Als N, Brewin CR, Harvey SE, Howell DCJ, Hudson N, Mythen MG, Smyth D, Weinman J, Welch J, Whitman C, Rowan KM; POPPI Trial Investigators.

JAMA. 2019 Feb 19;321(7):665-675. doi: 10.1001/jama.2019.0073.


ICU Structure and Outcomes Following Traumatic Brain Injury.

Menon DK, Rowan KM, Harrison DA.

Crit Care Med. 2019 Jan;47(1):e68-e69. doi: 10.1097/CCM.0000000000003386. No abstract available.


Psychological outcomes following a nurse-led preventative psychological intervention for critically ill patients trial: Statistical and health economic analysis plan.

Wulff J, Sadique Z, Grieve R, Howell D, Mouncey P, Wade D, Rowan KM, Harrison DA.

J Intensive Care Soc. 2018 Nov;19(4):281-286. doi: 10.1177/1751143718755016. Epub 2018 Jan 29.


Anxiety, Depression and Post Traumatic Stress Disorder after critical illness: a UK-wide prospective cohort study.

Hatch R, Young D, Barber V, Griffiths J, Harrison DA, Watkinson P.

Crit Care. 2018 Nov 23;22(1):310. doi: 10.1186/s13054-018-2223-6.


Relationship between height and outcomes among critically ill adults: a cohort study.

Vail EA, Harrison DA, Wunsch H.

Intensive Care Med. 2018 Dec;44(12):2122-2133. doi: 10.1007/s00134-018-5441-0. Epub 2018 Nov 12.


A Comparison of Mortality From Sepsis in Brazil and England: The Impact of Heterogeneity in General and Sepsis-Specific Patient Characteristics.

Ranzani OT, Shankar-Hari M, Harrison DA, Rabello LS, Salluh JIF, Rowan KM, Soares M.

Crit Care Med. 2019 Jan;47(1):76-84. doi: 10.1097/CCM.0000000000003438.


Restricted fluid bolus versus current practice in children with septic shock: the FiSh feasibility study and pilot RCT.

Inwald D, Canter RR, Woolfall K, O'Hara CB, Mouncey PR, Zenasni Z, Hudson N, Saunders S, Carter A, Jones N, Lyttle MD, Nadel S, Peters MJ, Harrison DA, Rowan KM.

Health Technol Assess. 2018 Sep;22(51):1-106. doi: 10.3310/hta22510.


Effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route for critically ill adult patients.

Sadique Z, Harrison DA, Bear DE, Rowan KM, Grieve R; CALORIES trial investigators.

J Crit Care. 2018 Aug 26. pii: S0883-9441(18)30351-4. doi: 10.1016/j.jcrc.2018.08.025. [Epub ahead of print] No abstract available.


'Lumping or splitting' in paediatric acute respiratory distress syndrome (PARDS).

De Luca D, Harrison DA, Peters MJ.

Intensive Care Med. 2018 Sep;44(9):1548-1550. doi: 10.1007/s00134-018-5323-5. Epub 2018 Aug 24. No abstract available.


Randomized Study of Early Continuous Positive Airways Pressure in Acute Respiratory Failure in Children With Impaired Immunity (SCARF) ISRCTN82853500.

Peters MJ, Agbeko R, Davis P, Klein N, Zenasni Z, Jones A, Mackerness C, George S, Veys P, Ray S, Mouncey PR, Harrison DA, Rowan K; SCARF Study Investigators and the Pediatric Intensive Care Society Study Group (PICS-SG).

Pediatr Crit Care Med. 2018 Oct;19(10):939-948. doi: 10.1097/PCC.0000000000001683.


Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial.

Inwald DP, Canter R, Woolfall K, Mouncey P, Zenasni Z, O'Hara C, Carter A, Jones N, Lyttle MD, Nadel S, Peters MJ, Harrison DA, Rowan KM; PERUKI (Paediatric Emergency Research in the UK and Ireland) and PICS SG (Paediatric Intensive Care Society Study Group).

Arch Dis Child. 2018 Aug 7. pii: archdischild-2018-314924. doi: 10.1136/archdischild-2018-314924. [Epub ahead of print]


Providing psychological support to people in intensive care: development and feasibility study of a nurse-led intervention to prevent acute stress and long-term morbidity.

Wade D, Als N, Bell V, Brewin C, D'Antoni D, Harrison DA, Harvey M, Harvey S, Howell D, Mouncey PR, Mythen M, Richards-Belle A, Smyth D, Weinman J, Welch J, Whitman C, Rowan KM; POPPI investigators.

BMJ Open. 2018 Jul 23;8(7):e021083. doi: 10.1136/bmjopen-2017-021083.


Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial.

Peters MJ, Jones GAL, Wiley D, Wulff J, Ramnarayan P, Ray S, Inwald D, Grocott M, Griksaitis M, Pappachan J, O'Neill L, Eaton S, Mouncey PR, Harrison DA, Rowan KM; Oxy-PICU Investigators for the Paediatric Intensive Care Society Study Group (PICS-SG).

Intensive Care Med. 2018 Aug;44(8):1240-1248. doi: 10.1007/s00134-018-5232-7. Epub 2018 Jun 4.


FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): a multicentre pilot randomised controlled trial of high-flow nasal cannula therapy versus continuous positive airway pressure in paediatric critical care.

Ramnarayan P, Lister P, Dominguez T, Habibi P, Edmonds N, Canter RR, Wulff J, Harrison DA, Mouncey PM, Peters MJ; United Kingdom Paediatric Intensive Care Society Study Group (PICS-SG).

Crit Care. 2018 Jun 4;22(1):144. doi: 10.1186/s13054-018-2080-3.


The organisation of critical care for burn patients in the UK: epidemiology and comparison of mortality prediction models.

Toft-Petersen AP, Ferrando-Vivas P, Harrison DA, Dunn K, Rowan KM.

Anaesthesia. 2018 Sep;73(9):1131-1140. doi: 10.1111/anae.14319. Epub 2018 May 15.


Seeing their side versus feeling their pain: Differential consequences of perspective-taking and empathy at work.

Longmire NH, Harrison DA.

J Appl Psychol. 2018 Aug;103(8):894-915. doi: 10.1037/apl0000307. Epub 2018 Apr 16.


Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI): protocol for a cluster-randomised clinical trial of a complex intervention.

Richards-Belle A, Mouncey PR, Wade D, Brewin CR, Emerson LM, Grieve R, Harrison DA, Harvey S, Howell D, Mythen M, Sadique Z, Smyth D, Weinman J, Welch J, Rowan KM; POPPI Trial Investigators.

BMJ Open. 2018 Feb 8;8(2):e020908. doi: 10.1136/bmjopen-2017-020908.


Estimating attributable fraction of mortality from sepsis to inform clinical trials.

Shankar-Hari M, Harrison DA, Rowan KM, Rubenfeld GD.

J Crit Care. 2018 Jun;45:33-39. doi: 10.1016/j.jcrc.2018.01.018. Epub 2018 Jan 31.


Incidence and Outcomes for Patients With Cirrhosis Admitted to the United Kingdom Critical Care Units.

McPhail MJW, Parrott F, Wendon JA, Harrison DA, Rowan KA, Bernal W.

Crit Care Med. 2018 May;46(5):705-712. doi: 10.1097/CCM.0000000000002961.


Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU).

Jones GAL, Ramnarayan P, Raman S, Inwald D, Grocott MPW, Eaton S, Ray S, Griksaitis MJ, Pappachan J, Wiley D, Mouncey PR, Wulff J, Harrison DA, Rowan KM, Peters MJ; Oxy-PICU Investigators for thePaediatric Intensive Care Society-Study Group (PICS-SG).

BMJ Open. 2017 Dec 14;7(12):e019253. doi: 10.1136/bmjopen-2017-019253.


Exploring the impact of using measured or estimated values for height and weight on the relationship between BMI and acute hospital mortality.

Toft-Petersen AP, Wulff J, Harrison DA, Ostermann M, Margarson M, Rowan KM, Dawson D.

J Crit Care. 2018 Apr;44:196-202. doi: 10.1016/j.jcrc.2017.11.021. Epub 2017 Nov 15.


Epidemiology of sepsis and septic shock in critical care units: comparison between sepsis-2 and sepsis-3 populations using a national critical care database.

Shankar-Hari M, Harrison DA, Rubenfeld GD, Rowan K.

Br J Anaesth. 2017 Oct 1;119(4):626-636. doi: 10.1093/bja/aex234.


Religious/Spiritual Struggle in Young Adult Hematopoietic Cell Transplant Survivors.

King SDW, Fitchett G, Murphy PE, Rajaee G, Pargament KI, Loggers ET, Harrison DA, Johnson RH.

J Adolesc Young Adult Oncol. 2018 Apr;7(2):210-216. doi: 10.1089/jayao.2017.0069. Epub 2017 Nov 3.


A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock.

O'Hara CB, Canter RR, Mouncey PR, Carter A, Jones N, Nadel S, Peters MJ, Lyttle MD, Harrison DA, Rowan KM, Inwald D, Woolfall K.

Arch Dis Child. 2018 Jan;103(1):28-32. doi: 10.1136/archdischild-2016-312515. Epub 2017 Aug 28.


The effect of postal questionnaire burden on response rate and answer patterns following admission to intensive care: a randomised controlled trial.

Hatch R, Young D, Barber V, Harrison DA, Watkinson P.

BMC Med Res Methodol. 2017 Mar 27;17(1):49. doi: 10.1186/s12874-017-0319-3.


Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.

PRISM Investigators, Rowan KM, Angus DC, Bailey M, Barnato AE, Bellomo R, Canter RR, Coats TJ, Delaney A, Gimbel E, Grieve RD, Harrison DA, Higgins AM, Howe B, Huang DT, Kellum JA, Mouncey PR, Music E, Peake SL, Pike F, Reade MC, Sadique MZ, Singer M, Yealy DM.

N Engl J Med. 2017 Jun 8;376(23):2223-2234. doi: 10.1056/NEJMoa1701380. Epub 2017 Mar 21.


Association of Intensive Care Unit Patient-to-Intensivist Ratios With Hospital Mortality.

Gershengorn HB, Harrison DA, Garland A, Wilcox ME, Rowan KM, Wunsch H.

JAMA Intern Med. 2017 Mar 1;177(3):388-396. doi: 10.1001/jamainternmed.2016.8457.


qSOFA for Identifying Sepsis Among Patients With Infection.

Lamontagne F, Harrison DA, Rowan KM.

JAMA. 2017 Jan 17;317(3):267-268. doi: 10.1001/jama.2016.19684. No abstract available.


Psychometric assessment of the Family Satisfaction in the Intensive Care Unit questionnaire in the United Kingdom.

Harrison DA, Ferrando-Vivas P, Wright SE, McColl E, Heyland DK, Rowan KM; Family-Reported Experiences Evaluation Study Investigators.

J Crit Care. 2017 Apr;38:346-350. doi: 10.1016/j.jcrc.2016.10.023. Epub 2016 Nov 5.


Development and validation of the new ICNARC model for prediction of acute hospital mortality in adult critical care.

Ferrando-Vivas P, Jones A, Rowan KM, Harrison DA.

J Crit Care. 2017 Apr;38:335-339. doi: 10.1016/j.jcrc.2016.11.031. Epub 2016 Nov 21.


Determining best methods to screen for religious/spiritual distress.

King SD, Fitchett G, Murphy PE, Pargament KI, Harrison DA, Loggers ET.

Support Care Cancer. 2017 Feb;25(2):471-479. doi: 10.1007/s00520-016-3425-6. Epub 2016 Oct 6.


The Assessment of Risk in Cardiothoracic Intensive Care (ARCtIC): prediction of hospital mortality after admission to cardiothoracic critical care.

Shahin J, Ferrando-Vivas P, Power GS, Biswas S, Webb ST, Rowan KM, Harrison DA.

Anaesthesia. 2016 Dec;71(12):1410-1416. doi: 10.1111/anae.13624. Epub 2016 Sep 26.


Predicting invasive fungal disease due to Candida species in non-neutropenic, critically ill, adult patients in United Kingdom critical care units.

Shahin J, Allen EJ, Patel K, Muskett H, Harvey SE, Edgeworth J, Kibbler CC, Barnes RA, Biswas S, Soni N, Rowan KM, Harrison DA; FIRE Study Investigators.

BMC Infect Dis. 2016 Sep 9;16:480. doi: 10.1186/s12879-016-1803-9.


Maternal morbidity and mortality from severe sepsis: a national cohort study.

Acosta CD, Harrison DA, Rowan K, Lucas DN, Kurinczuk JJ, Knight M.

BMJ Open. 2016 Aug 23;6(8):e012323. doi: 10.1136/bmjopen-2016-012323.


Palliative Care: A Partnership Across the Continuum of Care.

Spaulding A, Harrison DA, Harrison JP.

Health Care Manag (Frederick). 2016 Jul-Sep;35(3):189-98. doi: 10.1097/HCM.0000000000000115.


Increasing survival after admission to UK critical care units following cardiopulmonary resuscitation.

Nolan JP, Ferrando P, Soar J, Benger J, Thomas M, Harrison DA, Perkins GD.

Crit Care. 2016 Jul 9;20(1):219. doi: 10.1186/s13054-016-1390-6.


An evaluation of the clinical and cost-effectiveness of alternative care locations for critically ill adult patients with acute traumatic brain injury.

Grieve R, Sadique Z, Gomes M, Smith M, Lecky FE, Hutchinson PJ, Menon DK, Rowan KM, Harrison DA; Risk Adjustment In Neurocritical care (RAIN) Study Investigators.

Br J Neurosurg. 2016 Aug;30(4):388-96. doi: 10.3109/02688697.2016.1161166. Epub 2016 May 18.


A multicentre, randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route in critically ill patients (CALORIES).

Harvey SE, Parrott F, Harrison DA, Sadique MZ, Grieve RD, Canter RR, McLennan BK, Tan JC, Bear DE, Segaran E, Beale R, Bellingan G, Leonard R, Mythen MG, Rowan KM.

Health Technol Assess. 2016 Apr;20(28):1-144. doi: 10.3310/hta20280.


Relationship Between Peak Lactate and Patient Outcome Following High-Risk Gastrointestinal Surgery: Influence of the Nature of Their Surgery: Elective Versus Emergency.

Creagh-Brown BC, De Silva AP, Ferrando-Vivas P, Harrison DA.

Crit Care Med. 2016 May;44(5):918-25. doi: 10.1097/CCM.0000000000001567.


Children with dermatological conditions admitted to paediatric intensive care: analysis of a national clinical audit database.

George SM, Sen SM, Harrison DA, McShane P, Patel K, Darley CR.

Clin Exp Dermatol. 2016 Jun;41(4):403-6. doi: 10.1111/ced.12780. Epub 2015 Dec 18.


Family-Reported Experiences Evaluation (FREE) study: a mixed-methods study to evaluate families’ satisfaction with adult critical care services in the NHS.

Wright SE, Walmsley E, Harvey SE, Robinson E, Ferrando-Vivas P, Harrison DA, Canter RR, McColl E, Richardson A, Richardson M, Hinton L, Heyland DK, Rowan KM.

Southampton (UK): NIHR Journals Library; 2015 Dec.


Cost-effectiveness of a cardiac output-guided haemodynamic therapy algorithm in high-risk patients undergoing major gastrointestinal surgery.

Sadique Z, Harrison DA, Grieve R, Rowan KM, Pearse RM; OPTIMISE study group.

Perioper Med (Lond). 2015 Dec 14;4:13. doi: 10.1186/s13741-015-0024-x. eCollection 2015.


Risk-adjusted survival for adults following in-hospital cardiac arrest by day of week and time of day: observational cohort study.

Robinson EJ, Smith GB, Power GS, Harrison DA, Nolan J, Soar J, Spearpoint K, Gwinnutt C, Rowan KM.

BMJ Qual Saf. 2016 Nov;25(11):832-841. doi: 10.1136/bmjqs-2015-004223. Epub 2015 Dec 11.


Ups and downs of the expatriate experience? Understanding work adjustment trajectories and career outcomes.

Zhu J, Wanberg CR, Harrison DA, Diehn EW.

J Appl Psychol. 2016 Apr;101(4):549-68. doi: 10.1037/apl0000073. Epub 2015 Dec 14.


Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock.

Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Tan JC, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM.

Health Technol Assess. 2015 Nov;19(97):i-xxv, 1-150. doi: 10.3310/hta19970.

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