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Items: 1 to 50 of 259

1.

Molecular Signatures of Non-typeable Haemophilus influenzae Lung Adaptation in Pediatric Chronic Lung Disease.

Aziz A, Sarovich DS, Nosworthy E, Beissbarth J, Chang AB, Smith-Vaughan H, Price EP, Harris TM.

Front Microbiol. 2019 Jul 16;10:1622. doi: 10.3389/fmicb.2019.01622. eCollection 2019.

2.

Antimicrobial susceptibility and impact of macrolide antibiotics on Moraxella catarrhalis in the upper and lower airways of children with chronic endobronchial suppuration.

Hare KM, Seib KL, Chang AB, Harris TM, Spargo JC, Smith-Vaughan HC.

J Med Microbiol. 2019 Aug;68(8):1140-1147. doi: 10.1099/jmm.0.001033. Epub 2019 Jul 5.

PMID:
31274402
3.
4.

Incident haemodialysis and outcomes in the Top End of Australia.

Hughes JT, Majoni SW, Barzi F, Harris TM, Signal S, Lowah G, Kapojos J, Abeyaratne A, Sundaram M, Goldrick P, Jones SL, McFarlane R, Campbell LT, Stephens D, Cass A.

Aust Health Rev. 2019 Apr 18. doi: 10.1071/AH18230. [Epub ahead of print]

PMID:
30995950
5.

Method for culturing Candidatus Ornithobacterium hominis.

Lawrence KA, Harris TM, Salter SJ, Hall RW, Smith-Vaughan HC, Chang AB, Marsh RL.

J Microbiol Methods. 2019 Apr;159:157-160. doi: 10.1016/j.mimet.2019.03.006. Epub 2019 Mar 11.

PMID:
30871998
6.

Optimal targeting of BCL-family proteins in head and neck squamous cell carcinoma requires inhibition of both BCL-xL and MCL-1.

Ow TJ, Fulcher CD, Thomas C, Broin PÓ, López A, Reyna DE, Smith RV, Sarta C, Prystowsky MB, Schlecht NF, Schiff BA, Rosenblatt G, Belbin TJ, Harris TM, Childs GC, Kawachi N, Guha C, Gavathiotis E.

Oncotarget. 2019 Jan 11;10(4):494-510. doi: 10.18632/oncotarget.26563. eCollection 2019 Jan 11.

7.

Integrated Genomic and Functional microRNA Analysis Identifies miR-30-5p as a Tumor Suppressor and Potential Therapeutic Nanomedicine in Head and Neck Cancer.

Saleh AD, Cheng H, Martin SE, Si H, Ormanoglu P, Carlson S, Clavijo PE, Yang X, Das R, Cornelius S, Couper J, Chepeha D, Danilova L, Harris TM, Prystowsky MB, Childs GJ, Smith RV, Robertson AG, Jones SJM, Cherniack AD, Kim SS, Rait A, Pirollo KF, Chang EH, Chen Z, Van Waes C.

Clin Cancer Res. 2019 May 1;25(9):2860-2873. doi: 10.1158/1078-0432.CCR-18-0716. Epub 2019 Feb 5.

PMID:
30723145
8.

Cell mimetic liposomal nanocarriers for tailored delivery of vascular therapeutics.

Mattern-Schain SI, Fisher RK, West PC, Grimsley LB, Harris TM, Grandas OH, Best MD, Mountain DJH.

Chem Phys Lipids. 2019 Jan;218:149-157. doi: 10.1016/j.chemphyslip.2018.12.009. Epub 2018 Dec 21.

PMID:
30582896
9.

Absolute Configurations of Naturally Occurring [5]- and [3]-Ladderanoic Acids: Isolation, Chiroptical Spectroscopy, and Crystallography.

Raghavan V, Johnson JL, Stec DF, Song B, Zajac G, Baranska M, Harris CM, Schley ND, Polavarapu PL, Harris TM.

J Nat Prod. 2018 Dec 28;81(12):2654-2666. doi: 10.1021/acs.jnatprod.8b00458. Epub 2018 Dec 18.

PMID:
30562024
10.

Soil-Transmitted Helminths in Children in a Remote Aboriginal Community in the Northern Territory: Hookworm is Rare but Strongyloides stercoralis and Trichuris trichiura Persist.

Holt DC, Shield J, Harris TM, Mounsey KE, Aland K, McCarthy JS, Currie BJ, Kearns TM.

Trop Med Infect Dis. 2017 Oct 4;2(4). pii: E51. doi: 10.3390/tropicalmed2040051.

11.

Investigation of trimethoprim/sulfamethoxazole resistance in an emerging sequence type 5 methicillin-resistant Staphylococcus aureus clone reveals discrepant resistance reporting.

Harris TM, Bowen AC, Holt DC, Sarovich DS, Stevens K, Currie BJ, Howden BP, Carapetis JR, Giffard PM, Tong SYC.

Clin Microbiol Infect. 2018 Sep;24(9):1027-1029. doi: 10.1016/j.cmi.2018.04.020. Epub 2018 May 1. No abstract available.

12.

CtGEM typing: Discrimination of Chlamydia trachomatis ocular and urogenital strains and major evolutionary lineages by high resolution melting analysis of two amplified DNA fragments.

Giffard PM, Andersson P, Wilson J, Buckley C, Lilliebridge R, Harris TM, Kleinecke M, O'Grady KF, Huston WM, Lambert SB, Whiley DM, Holt DC.

PLoS One. 2018 Apr 10;13(4):e0195454. doi: 10.1371/journal.pone.0195454. eCollection 2018.

13.

Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases.

Vazquez ML, Kaila N, Strohbach JW, Trzupek JD, Brown MF, Flanagan ME, Mitton-Fry MJ, Johnson TA, TenBrink RE, Arnold EP, Basak A, Heasley SE, Kwon S, Langille J, Parikh MD, Griffin SH, Casavant JM, Duclos BA, Fenwick AE, Harris TM, Han S, Caspers N, Dowty ME, Yang X, Banker ME, Hegen M, Symanowicz PT, Li L, Wang L, Lin TH, Jussif J, Clark JD, Telliez JB, Robinson RP, Unwalla R.

J Med Chem. 2018 Feb 8;61(3):1130-1152. doi: 10.1021/acs.jmedchem.7b01598. Epub 2018 Jan 23.

PMID:
29298069
14.

Suspected cases of intracontinental Burkholderia pseudomallei sequence type homoplasy resolved using whole-genome sequencing.

Aziz A, Sarovich DS, Harris TM, Kaestli M, McRobb E, Mayo M, Currie BJ, Price EP.

Microb Genom. 2017 Nov;3(11). doi: 10.1099/mgen.0.000139.

15.

Apolipoprotein E Promotes Invasion in Oral Squamous Cell Carcinoma.

Jayakar SK, Loudig O, Brandwein-Gensler M, Kim RS, Ow TJ, Ustun B, Harris TM, Prystowsky MB, Childs G, Segall JE, Belbin TJ.

Am J Pathol. 2017 Oct;187(10):2259-2272. doi: 10.1016/j.ajpath.2017.06.016. Epub 2017 Jul 24.

16.

Simultaneous identification of Haemophilus influenzae and Haemophilus haemolyticus using real-time PCR.

Price EP, Harris TM, Spargo J, Nosworthy E, Beissbarth J, Chang AB, Smith-Vaughan HC, Sarovich DS.

Future Microbiol. 2017 Jun;12:585-593. doi: 10.2217/fmb-2016-0215. Epub 2017 Jun 12.

17.

miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin.

Jimenez L, Lim J, Burd B, Harris TM, Ow TJ, Kawachi N, Belbin TJ, Angeletti R, Prystowsky MB, Childs G, Segall JE.

Am J Pathol. 2017 Jul;187(7):1523-1536. doi: 10.1016/j.ajpath.2017.02.019. Epub 2017 May 10.

18.

Culture of non-typeable Haemophilus influenzae from the nasopharynx: Not all media are equal.

Harris TM, Rumaseb A, Beissbarth J, Barzi F, Leach AJ, Smith-Vaughan HC.

J Microbiol Methods. 2017 Jun;137:3-5. doi: 10.1016/j.mimet.2017.03.012. Epub 2017 Mar 22.

PMID:
28342745
19.

Laryngotracheal separation following blunt neck trauma.

Humenansky KM, Harris TM, Hoffman DM.

Am J Emerg Med. 2017 Apr;35(4):669.e5-669.e7. doi: 10.1016/j.ajem.2016.11.031. Epub 2016 Nov 12. No abstract available.

PMID:
27876540
20.

Impostor syndrome and burnout among American medical students: a pilot study.

Villwock JA, Sobin LB, Koester LA, Harris TM.

Int J Med Educ. 2016 Oct 31;7:364-369. doi: 10.5116/ijme.5801.eac4.

21.

Catalysts of DNA Strand Cleavage at Apurinic/Apyrimidinic Sites.

Minko IG, Jacobs AC, de Leon AR, Gruppi F, Donley N, Harris TM, Rizzo CJ, McCullough AK, Lloyd RS.

Sci Rep. 2016 Jul 1;6:28894. doi: 10.1038/srep28894.

22.

External auditory canal stenting with nonlatex glove and Gelfoam.

Pan JC, Harris TM.

Ear Nose Throat J. 2016 Feb;95(2):E25-6.

PMID:
26930340
23.

Intranasal midazolam for anxiolysis in closed reduction of nasal fractures in children.

Plum AW, Harris TM.

Int J Pediatr Otorhinolaryngol. 2015 Jul;79(7):1121-3. doi: 10.1016/j.ijporl.2015.05.006. Epub 2015 May 18.

PMID:
26026891
24.

Epigenetic changes in the CDKN2A locus are associated with differential expression of P16INK4A and P14ARF in HPV-positive oropharyngeal squamous cell carcinoma.

Schlecht NF, Ben-Dayan M, Anayannis N, Lleras RA, Thomas C, Wang Y, Smith RV, Burk RD, Harris TM, Childs G, Ow TJ, Prystowsky MB, Belbin TJ.

Cancer Med. 2015 Mar;4(3):342-53. doi: 10.1002/cam4.374. Epub 2015 Jan 26.

25.

Proteomic analysis of oral cavity squamous cell carcinoma specimens identifies patient outcome-associated proteins.

Harris TM, Du P, Kawachi N, Belbin TJ, Wang Y, Schlecht NF, Ow TJ, Keller CE, Childs GJ, Smith RV, Angeletti RH, Prystowsky MB, Lim J.

Arch Pathol Lab Med. 2015 Apr;139(4):494-507. doi: 10.5858/arpa.2014-0131-OA. Epub 2014 Oct 8.

26.

Head and neck myiasis, cutaneous malignancy, and infection: a case series and review of the literature.

Villwock JA, Harris TM.

J Emerg Med. 2014 Aug;47(2):e37-41. doi: 10.1016/j.jemermed.2014.04.024. Epub 2014 Jun 6. Review.

PMID:
24910364
27.

Investigation of the mechanism of racemization of litronesib in aqueous solution: unexpected base-catalyzed inversion of a fully substituted carbon chiral center.

Baertschi SW, Jansen PJ, Montgomery RM, Smith WK, Draper JR, Myers DP, Houghton PG, Sharp VS, Guisbert AL, Zhuang H, Watkins MA, Stephenson GA, Harris TM.

J Pharm Sci. 2014 Sep;103(9):2797-2808. doi: 10.1002/jps.23918. Epub 2014 Mar 14.

PMID:
24633856
28.

On-column nitrosation of amines observed in liquid chromatography impurity separations employing ammonium hydroxide and acetonitrile as mobile phase.

Myers DP, Hetrick EM, Liang Z, Hadden CE, Bandy S, Kemp CA, Harris TM, Baertschi SW.

J Chromatogr A. 2013 Dec 6;1319:57-64. doi: 10.1016/j.chroma.2013.10.021. Epub 2013 Oct 15.

PMID:
24182763
29.

Unique DNA methylation loci distinguish anatomic site and HPV status in head and neck squamous cell carcinoma.

Lleras RA, Smith RV, Adrien LR, Schlecht NF, Burk RD, Harris TM, Childs G, Prystowsky MB, Belbin TJ.

Clin Cancer Res. 2013 Oct 1;19(19):5444-55. doi: 10.1158/1078-0432.CCR-12-3280. Epub 2013 Jul 26.

30.

Pyridone-conjugated monobactam antibiotics with gram-negative activity.

Brown MF, Mitton-Fry MJ, Arcari JT, Barham R, Casavant J, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Lall MS, Lemmon MM, Li C, Lin J, McCurdy SP, McElroy E, McPherson C, Marr ES, Mueller JP, Mullins L, Nikitenko AA, Noe MC, Penzien J, Plummer MS, Schuff BP, Shanmugasundaram V, Starr JT, Sun J, Tomaras A, Young JA, Zaniewski RP.

J Med Chem. 2013 Jul 11;56(13):5541-52. doi: 10.1021/jm400560z. Epub 2013 Jun 27.

PMID:
23755848
31.

Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infections.

Mitton-Fry MJ, Arcari JT, Brown MF, Casavant JM, Finegan SM, Flanagan ME, Gao H, George DM, Gerstenberger BS, Han S, Hardink JR, Harris TM, Hoang T, Huband MD, Irvine R, Lall MS, Megan Lemmon M, Li C, Lin J, McCurdy SP, Mueller JP, Mullins L, Niosi M, Noe MC, Pattavina D, Penzien J, Plummer MS, Risley H, Schuff BP, Shanmugasundaram V, Starr JT, Sun J, Winton J, Young JA.

Bioorg Med Chem Lett. 2012 Sep 15;22(18):5989-94. doi: 10.1016/j.bmcl.2012.07.005. Epub 2012 Jul 20. Erratum in: Bioorg Med Chem Lett. 2015 Sep 15;25(18):4029.

PMID:
22892121
32.

Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections.

Montgomery JI, Brown MF, Reilly U, Price LM, Abramite JA, Arcari J, Barham R, Che Y, Chen JM, Chung SW, Collantes EM, Desbonnet C, Doroski M, Doty J, Engtrakul JJ, Harris TM, Huband M, Knafels JD, Leach KL, Liu S, Marfat A, McAllister L, McElroy E, Menard CA, Mitton-Fry M, Mullins L, Noe MC, O'Donnell J, Oliver R, Penzien J, Plummer M, Shanmugasundaram V, Thoma C, Tomaras AP, Uccello DP, Vaz A, Wishka DG.

J Med Chem. 2012 Feb 23;55(4):1662-70. doi: 10.1021/jm2014875. Epub 2012 Feb 8.

PMID:
22257165
33.

Potent inhibitors of LpxC for the treatment of Gram-negative infections.

Brown MF, Reilly U, Abramite JA, Arcari JT, Oliver R, Barham RA, Che Y, Chen JM, Collantes EM, Chung SW, Desbonnet C, Doty J, Doroski M, Engtrakul JJ, Harris TM, Huband M, Knafels JD, Leach KL, Liu S, Marfat A, Marra A, McElroy E, Melnick M, Menard CA, Montgomery JI, Mullins L, Noe MC, O'Donnell J, Penzien J, Plummer MS, Price LM, Shanmugasundaram V, Thoma C, Uccello DP, Warmus JS, Wishka DG.

J Med Chem. 2012 Jan 26;55(2):914-23. doi: 10.1021/jm2014748. Epub 2012 Jan 11.

PMID:
22175825
34.

Deoxyguanosine forms a bis-adduct with E,E-muconaldehyde, an oxidative metabolite of benzene: implications for the carcinogenicity of benzene.

Harris CM, Stec DF, Christov PP, Kozekov ID, Rizzo CJ, Harris TM.

Chem Res Toxicol. 2011 Nov 21;24(11):1944-56. doi: 10.1021/tx2002838. Epub 2011 Oct 26.

35.

Hypermethylation of a cluster of Krüppel-type zinc finger protein genes on chromosome 19q13 in oropharyngeal squamous cell carcinoma.

Lleras RA, Adrien LR, Smith RV, Brown B, Jivraj N, Keller C, Sarta C, Schlecht NF, Harris TM, Childs G, Prystowsky MB, Belbin TJ.

Am J Pathol. 2011 May;178(5):1965-74. doi: 10.1016/j.ajpath.2011.01.049.

36.

Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal.

Kozekov ID, Turesky RJ, Alas GR, Harris CM, Harris TM, Rizzo CJ.

Chem Res Toxicol. 2010 Nov 15;23(11):1701-13. doi: 10.1021/tx100179g. Epub 2010 Oct 22.

37.

Structure-activity relationships and hepatic safety risks of thiazole agonists of the thrombopoietin receptor.

Antipas AS, Blumberg LC, Brissette WH, Brown MF, Casavant JM, Doty JL, Driscoll J, Harris TM, Jones CS, McCurdy SP, McElroy E, Mitton-Fry M, Munchhof MJ, Reim DA, Reiter LA, Ripp SL, Shavnya A, Smeets MI, Trevena KA.

Bioorg Med Chem Lett. 2010 Jul 15;20(14):4069-72. doi: 10.1016/j.bmcl.2010.05.087. Epub 2010 May 26.

PMID:
20558059
38.

Canada's National Advisory Committee on Immunization (NACI): evidence-based decision-making on vaccines and immunization.

Ismail SJ, Langley JM, Harris TM, Warshawsky BF, Desai S, FarhangMehr M.

Vaccine. 2010 Apr 19;28 Suppl 1:A58-63. doi: 10.1016/j.vaccine.2010.02.035.

39.

Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5'-CpG-3' and 5'-GpC-3' sequence contexts.

Huang H, Dooley PA, Harris CM, Harris TM, Stone MP.

Chem Res Toxicol. 2009 Nov;22(11):1810-6. doi: 10.1021/tx900225c.

40.

Structural perturbations induced by the alpha-anomer of the aflatoxin B(1) formamidopyrimidine adduct in duplex and single-strand DNA.

Brown KL, Voehler MW, Magee SM, Harris CM, Harris TM, Stone MP.

J Am Chem Soc. 2009 Nov 11;131(44):16096-107. doi: 10.1021/ja902052v.

41.

Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence.

Huang H, Kim HY, Kozekov ID, Cho YJ, Wang H, Kozekova A, Harris TM, Rizzo CJ, Stone MP.

J Am Chem Soc. 2009 Jun 24;131(24):8416-24. doi: 10.1021/ja809543j.

42.

Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study.

Njajou OT, Hsueh WC, Blackburn EH, Newman AB, Wu SH, Li R, Simonsick EM, Harris TM, Cummings SR, Cawthon RM; Health ABC study.

J Gerontol A Biol Sci Med Sci. 2009 Aug;64(8):860-4. doi: 10.1093/gerona/glp061. Epub 2009 May 12.

43.

Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.

Minko IG, Kozekov ID, Harris TM, Rizzo CJ, Lloyd RS, Stone MP.

Chem Res Toxicol. 2009 May;22(5):759-78. doi: 10.1021/tx9000489. Review.

44.

The development and evaluation of monoclonal antibodies for the detection of polycyclic aromatic hydrocarbons.

Spier CR, Bromage ES, Harris TM, Unger MA, Kaattari SL.

Anal Biochem. 2009 Apr 15;387(2):287-93. doi: 10.1016/j.ab.2009.01.020. Epub 2009 Jan 21.

PMID:
19344658
45.

Recording video endoscopy using a portable media device: a novel solution in the age of digital media.

Harris TM, Goyal P.

Laryngoscope. 2009 Mar;119(3):500-1. doi: 10.1002/lary.20104. No abstract available.

PMID:
19235740
46.

The identification of orally bioavailable thrombopoietin agonists.

Munchhof MJ, Antipas AS, Blumberg LC, Brissette WH, Brown MF, Casavant JM, Doty JL, Driscoll J, Harris TM, Wolf-Gouveia LA, Jones CS, Li Q, Linde RG, Lira PD, Marfat A, McElroy E, Mitton-Fry M, McCurdy SP, Reiter LA, Ripp SL, Shavnya A, Thomasco LM, Trevena KA.

Bioorg Med Chem Lett. 2009 Mar 1;19(5):1428-30. doi: 10.1016/j.bmcl.2009.01.032. Epub 2009 Jan 15.

PMID:
19186055
47.

A religious framework as a lens for understanding the intersection of genetics, health, and disease.

Harris TM, Keeley B, Barrientos S, Gronnvoll M, Landau J, Groscurth CR, Shen L, Cheng Y, Cisneros JD.

Am J Med Genet C Semin Med Genet. 2009 Feb 15;151C(1):22-30. doi: 10.1002/ajmg.c.30192.

49.

Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI.

VanderVeen LA, Harris TM, Jen-Jacobson L, Marnett LJ.

Chem Res Toxicol. 2008 Sep;21(9):1733-8. doi: 10.1021/tx800092g. Epub 2008 Aug 9.

50.

The formamidopyrimidine derivative of 7-(2-oxoethyl)-2'-deoxyguanosine.

Christov PP, Kozekov ID, Rizzo CJ, Harris TM.

Chem Res Toxicol. 2008 Sep;21(9):1777-86. doi: 10.1021/tx800142m. Epub 2008 Aug 9.

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