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Apical polarity proteins recruit the RhoGEF Cysts to promote junctional myosin assembly.

Silver JT, Wirtz-Peitz F, Simões S, Pellikka M, Yan D, Binari R, Nishimura T, Li Y, Harris TJC, Perrimon N, Tepass U.

J Cell Biol. 2019 Oct 7;218(10):3397-3414. doi: 10.1083/jcb.201807106. Epub 2019 Aug 13.


BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival.

Lee EF, Harris TJ, Tran S, Evangelista M, Arulananda S, John T, Ramnac C, Hobbs C, Zhu H, Gunasingh G, Segal D, Behren A, Cebon J, Dobrovic A, Mariadason JM, Strasser A, Rohrbeck L, Haass NK, Herold MJ, Fairlie WD.

Cell Death Dis. 2019 Apr 24;10(5):342. doi: 10.1038/s41419-019-1568-3.


Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.

Lee EF, Smith NA, Soares da Costa TP, Meftahi N, Yao S, Harris TJ, Tran S, Pettikiriarachchi A, Perugini MA, Keizer DW, Evangelista M, Smith BJ, Fairlie WD.

Autophagy. 2019 May;15(5):785-795. doi: 10.1080/15548627.2018.1564557. Epub 2019 Jan 9.


Dynamics of PAR Proteins Explain the Oscillation and Ratcheting Mechanisms in Dorsal Closure.

Durney CH, Harris TJC, Feng JJ.

Biophys J. 2018 Dec 4;115(11):2230-2241. doi: 10.1016/j.bpj.2018.10.014. Epub 2018 Oct 24.


National Landscape of General Surgery Mock Oral Examination Practices: Survey of Residency Program Directors.

Kimbrough MK, Thrush CR, Smeds MR, Cobos RJ, Harris TJ, Bentley FR.

J Surg Educ. 2018 Nov;75(6):e54-e60. doi: 10.1016/j.jsurg.2018.07.012. Epub 2018 Aug 16.


Collision of Expanding Actin Caps with Actomyosin Borders for Cortical Bending and Mitotic Rounding in a Syncytium.

Zhang Y, Yu JC, Jiang T, Fernandez-Gonzalez R, Harris TJC.

Dev Cell. 2018 Jun 4;45(5):551-564.e4. doi: 10.1016/j.devcel.2018.04.024. Epub 2018 May 24.


Biliary Stenosis and Gastric Outlet Obstruction: Late Complications After Acute Pancreatitis With Pancreatic Duct Disruption.

Sugimoto M, Sonntag DP, Flint GS, Boyce CJ, Kirkham JC, Harris TJ, Carr SM, Nelson BD, Bell DA, Barton JG, Traverso LW.

Pancreas. 2018 Jul;47(6):772-777. doi: 10.1097/MPA.0000000000001064.


Severe acute gallstone pancreatitis with diffuse hemorrhagic gastritis.

Harris TJ, Beck WC, Bhavaraju A, Davis B, Kimbrough MK, Jensen JC, Privratsky A, Taylor JR, Sexton KW.

J Surg Case Rep. 2018 Mar 31;2018(3):rjy048. doi: 10.1093/jscr/rjy048. eCollection 2018 Mar.


Organizing Complex Tissue Architecture by Pushing and Pulling Cell Contacts.

Zhang Y, Harris TJC.

Dev Cell. 2018 Feb 26;44(4):407-409. doi: 10.1016/j.devcel.2018.02.003.


Visual Sensor for Sterilization of Polymer Fixtures Using Embedded Mesoporous Silicon Photonic Crystals.

Kumeria T, Wang J, Chan N, Harris TJ, Sailor MJ.

ACS Sens. 2018 Jan 26;3(1):143-150. doi: 10.1021/acssensors.7b00764. Epub 2018 Jan 17.


Protein clustering for cell polarity: Par-3 as a paradigm.

Harris TJC.

F1000Res. 2017 Aug 31;6:1620. doi: 10.12688/f1000research.11976.1. eCollection 2017. Review.


Sculpting epithelia with planar polarized actomyosin networks: Principles from Drosophila.

Harris TJC.

Semin Cell Dev Biol. 2018 Sep;81:54-61. doi: 10.1016/j.semcdb.2017.07.042. Epub 2017 Jul 29. Review.


An Actomyosin-Arf-GEF Negative Feedback Loop for Tissue Elongation under Stress.

West JJ, Zulueta-Coarasa T, Maier JA, Lee DM, Bruce AEE, Fernandez-Gonzalez R, Harris TJC.

Curr Biol. 2017 Aug 7;27(15):2260-2270.e5. doi: 10.1016/j.cub.2017.06.038. Epub 2017 Jul 20.


Key roles of Arf small G proteins and biosynthetic trafficking for animal development.

Rodrigues FF, Harris TJC.

Small GTPases. 2019 Nov;10(6):403-410. doi: 10.1080/21541248.2017.1304854. Epub 2017 Apr 17.


The Arf GAP Asap promotes Arf1 function at the Golgi for cleavage furrow biosynthesis in Drosophila.

Rodrigues FF, Shao W, Harris TJ.

Mol Biol Cell. 2016 Oct 15;27(20):3143-3155. Epub 2016 Aug 17.


What factors support older people to increase their physical activity levels? An exploratory analysis of the experiences of PACE-Lift trial participants.

Victor CR, Rogers A, Woodcock A, Beighton C, Cook DG, Kerry SM, Iliffe S, Whincup P, Ussher M, Harris TJ.

Arch Gerontol Geriatr. 2016 Nov-Dec;67:1-6. doi: 10.1016/j.archger.2016.06.006. Epub 2016 Jun 11.


Cadherin Trafficking for Tissue Morphogenesis: Control and Consequences.

West JJ, Harris TJ.

Traffic. 2016 Dec;17(12):1233-1243. doi: 10.1111/tra.12407. Epub 2016 May 19. Review.


Better Outcomes if Percutaneous Drainage Is Used Early and Proactively in the Course of Necrotizing Pancreatitis.

Sugimoto M, Sonntag DP, Flint GS, Boyce CJ, Kirkham JC, Harris TJ, Carr SM, Nelson BD, Bell DA, Barton JG, Traverso LW.

J Vasc Interv Radiol. 2016 Mar;27(3):418-25. doi: 10.1016/j.jvir.2015.11.054. Epub 2016 Jan 21.


PH Domain-Arf G Protein Interactions Localize the Arf-GEF Steppke for Cleavage Furrow Regulation in Drosophila.

Lee DM, Rodrigues FF, Yu CG, Swan M, Harris TJ.

PLoS One. 2015 Nov 10;10(11):e0142562. doi: 10.1371/journal.pone.0142562. eCollection 2015.


A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion.

Jiang T, McKinley RF, McGill MA, Angers S, Harris TJ.

Curr Biol. 2015 Oct 19;25(20):2701-8. doi: 10.1016/j.cub.2015.08.063. Epub 2015 Oct 8.


Direct Percutaneous Repair of Left Ventricular Pseudoaneurysm via Transthoracic Deployment of a Ventricular Septal Defect Closure Device.

Moriarty J, Harris TJ, Vorobiof G, Kwon M, Aboulhosn J.

Tex Heart Inst J. 2015 Aug 1;42(4):362-6. doi: 10.14503/THIJ-14-4243. eCollection 2015 Aug.


Polarized E-cadherin endocytosis directs actomyosin remodeling during embryonic wound repair.

Hunter MV, Lee DM, Harris TJ, Fernandez-Gonzalez R.

J Cell Biol. 2015 Aug 31;210(5):801-16. doi: 10.1083/jcb.201501076. Epub 2015 Aug 24.


A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.

Garama DJ, Harris TJ, White CL, Rossello FJ, Abdul-Hay M, Gough DJ, Levy DE.

Mol Cell Biol. 2015 Nov;35(21):3646-56. doi: 10.1128/MCB.00541-15. Epub 2015 Aug 17.


Promising Targets for the Treatment of Neurodegenerative Diseases.

Budd Haeberlein SL, Harris TJ.

Clin Pharmacol Ther. 2015 Nov;98(5):492-501. doi: 10.1002/cpt.195. Epub 2015 Sep 29. Review.


Germ Cell Segregation from the Drosophila Soma Is Controlled by an Inhibitory Threshold Set by the Arf-GEF Steppke.

Lee DM, Wilk R, Hu J, Krause HM, Harris TJ.

Genetics. 2015 Jul;200(3):863-72. doi: 10.1534/genetics.115.176867. Epub 2015 May 13.


On-demand pulsatile intracerebral delivery of carisbamate with closed-loop direct neurostimulation therapy in an electrically induced self-sustained focal-onset epilepsy rat model.

Mangubat EZ, Kellogg RG, Harris TJ Jr, Rossi MA.

J Neurosurg. 2015 Jun;122(6):1283-92. doi: 10.3171/2015.1.JNS14946. Epub 2015 Feb 27.


A percutaneous drainage protocol for severe and moderately severe acute pancreatitis.

Sugimoto M, Sonntag DP, Flint GS, Boyce CJ, Kirkham JC, Harris TJ, Carr SM, Nelson BD, Barton JG, Traverso LW.

Surg Endosc. 2015 Nov;29(11):3282-91. doi: 10.1007/s00464-015-4077-1. Epub 2015 Jan 29.


Registration of Zak ERA8 Soft White Spring Wheat Germplasm with Enhanced Response to ABA and Increased Seed Dormancy.

Martinez SA, Schramm EC, Harris TJ, Kidwell KK, Garland-Campbell K, Steber CM.

J Plant Regist. 2014 May 1;8(2):217-220.


Stepping stone: a cytohesin adaptor for membrane cytoskeleton restraint in the syncytial Drosophila embryo.

Liu J, Lee DM, Yu CG, Angers S, Harris TJ.

Mol Biol Cell. 2015 Feb 15;26(4):711-25. doi: 10.1091/mbc.E14-11-1554. Epub 2014 Dec 24.


Spontaneous spinal epidural abscess in a 21-month-old child.

Harris TJ, Seamon JP.

Am J Emerg Med. 2014 Dec;32(12):1558.e1-2. doi: 10.1016/j.ajem.2014.05.029. Epub 2014 May 24.


Coordinating the cytoskeleton and endocytosis for regulated plasma membrane growth in the early Drosophila embryo.

Lee DM, Harris TJ.

Bioarchitecture. 2014 Mar-Apr;4(2):68-74. doi: 10.4161/bioa.28949. Epub 2014 Apr 23.


Peptide binding properties of the three PDZ domains of Bazooka (Drosophila Par-3).

Yu CG, Tonikian R, Felsensteiner C, Jhingree JR, Desveaux D, Sidhu SS, Harris TJ.

PLoS One. 2014 Jan 22;9(1):e86412. doi: 10.1371/journal.pone.0086412. eCollection 2014.


Immune modulation and stereotactic radiation: improving local and abscopal responses.

Zeng J, Harris TJ, Lim M, Drake CG, Tran PT.

Biomed Res Int. 2013;2013:658126. doi: 10.1155/2013/658126. Epub 2013 Nov 14. Review.


Adherens junction distribution mechanisms during cell-cell contact elongation in Drosophila.

Goldenberg G, Harris TJ.

PLoS One. 2013 Nov 4;8(11):e79613. doi: 10.1371/journal.pone.0079613. eCollection 2013.


Bazooka inhibits aPKC to limit antagonism of actomyosin networks during amnioserosa apical constriction.

David DJ, Wang Q, Feng JJ, Harris TJ.

Development. 2013 Dec;140(23):4719-29. doi: 10.1242/dev.098491. Epub 2013 Oct 30.


Diamide linked γ-cyclodextrin dimers as molecular-scale delivery systems for the medicinal pigment curcumin to prostate cancer cells.

Harada T, Giorgio L, Harris TJ, Pham DT, Ngo HT, Need EF, Coventry BJ, Lincoln SF, Easton CJ, Buchanan G, Kee TW.

Mol Pharm. 2013 Dec 2;10(12):4481-90. doi: 10.1021/mp400309s. Epub 2013 Nov 12.


An Arf-GEF regulates antagonism between endocytosis and the cytoskeleton for Drosophila blastoderm development.

Lee DM, Harris TJ.

Curr Biol. 2013 Nov 4;23(21):2110-20. doi: 10.1016/j.cub.2013.08.058. Epub 2013 Oct 10.


Combined treatment effects of radiation and immunotherapy: studies in an autochthonous prostate cancer model.

Wada S, Harris TJ, Tryggestad E, Yoshimura K, Zeng J, Yen HR, Getnet D, Grosso JF, Bruno TC, De Marzo AM, Netto GJ, Pardoll DM, DeWeese TL, Wong J, Drake CG.

Int J Radiat Oncol Biol Phys. 2013 Nov 15;87(4):769-76. doi: 10.1016/j.ijrobp.2013.07.015. Epub 2013 Sep 21.


Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer.

Wada S, Jackson CM, Yoshimura K, Yen HR, Getnet D, Harris TJ, Goldberg MV, Bruno TC, Grosso JF, Durham N, Netto GJ, Pardoll DM, Drake CG.

J Transl Med. 2013 Apr 4;11:89. doi: 10.1186/1479-5876-11-89.


Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas.

Zeng J, See AP, Phallen J, Jackson CM, Belcaid Z, Ruzevick J, Durham N, Meyer C, Harris TJ, Albesiano E, Pradilla G, Ford E, Wong J, Hammers HJ, Mathios D, Tyler B, Brem H, Tran PT, Pardoll D, Drake CG, Lim M.

Int J Radiat Oncol Biol Phys. 2013 Jun 1;86(2):343-9. doi: 10.1016/j.ijrobp.2012.12.025. Epub 2013 Feb 22.


Visceral blood flow modulation: potential therapy for morbid obesity.

Harris TJ, Murphy TP, Jay BS, Hampson CO, Zafar AM.

Cardiovasc Intervent Radiol. 2013 Jun;36(3):803-8. doi: 10.1007/s00270-013-0560-z. Epub 2013 Feb 5.


Primer on tumor immunology and cancer immunotherapy.

Harris TJ, Drake CG.

J Immunother Cancer. 2013 Jul 29;1:12. doi: 10.1186/2051-1426-1-12. eCollection 2013. Review.


Research resource: interplay between the genomic and transcriptional networks of androgen receptor and estrogen receptor α in luminal breast cancer cells.

Need EF, Selth LA, Harris TJ, Birrell SN, Tilley WD, Buchanan G.

Mol Endocrinol. 2012 Nov;26(11):1941-52. doi: 10.1210/me.2011-1314. Epub 2012 Sep 28.


Displacement of basolateral Bazooka/PAR-3 by regulated transport and dispersion during epithelial polarization in Drosophila.

McKinley RF, Harris TJ.

Mol Biol Cell. 2012 Nov;23(22):4465-71. doi: 10.1091/mbc.E12-09-0655. Epub 2012 Sep 26.


Interactions between the PDZ domains of Bazooka (Par-3) and phosphatidic acid: in vitro characterization and role in epithelial development.

Yu CG, Harris TJ.

Mol Biol Cell. 2012 Sep;23(18):3743-53. doi: 10.1091/mbc.E12-03-0196. Epub 2012 Jul 25.


An introduction to adherens junctions: from molecular mechanisms to tissue development and disease.

Harris TJ.

Subcell Biochem. 2012;60:1-5. doi: 10.1007/978-94-007-4186-7_1. Review.


Fire-retardant clothing-related dermatitis.

McConnell DC, Harris TJ, Tucker SB.

Dermatitis. 2012 Jan-Feb;23(1):27-31. doi: 10.1097/DER.0b013e31823d18ef.


Assembly of Bazooka polarity landmarks through a multifaceted membrane-association mechanism.

McKinley RF, Yu CG, Harris TJ.

J Cell Sci. 2012 Mar 1;125(Pt 5):1177-90. doi: 10.1242/jcs.091884. Epub 2012 Feb 2.


Adherens junction assembly and function in the Drosophila embryo.

Harris TJ.

Int Rev Cell Mol Biol. 2012;293:45-83. doi: 10.1016/B978-0-12-394304-0.00007-5. Review.


Live imaging of Drosophila embryos: quantifying protein numbers and dynamics at subcellular locations.

David DJ, McGill MA, McKinley RF, Harris TJ.

Methods Mol Biol. 2012;839:1-17. doi: 10.1007/978-1-61779-510-7_1.


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