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Agonistic anti-CD148 monoclonal antibody attenuates diabetic nephropathy in mice.

Takahashi K, Kim RH, Pasic L, He L, Nagasaka S, Katagiri D, May T, Shimizu A, Harris RC, Mernaugh RL, Takahashi T.

Am J Physiol Renal Physiol. 2020 Mar 1;318(3):F647-F659. doi: 10.1152/ajprenal.00288.2019. Epub 2020 Jan 27.


How the Kidney Health Initiative Catalyzes Innovation in a Dynamic Environment.

Harris RC, Cahill Z.

Clin J Am Soc Nephrol. 2019 Dec 6. pii: CJN.11060919. doi: 10.2215/CJN.11060919. [Epub ahead of print] No abstract available.


Potential effect of age of BCG vaccination on global paediatric tuberculosis mortality: a modelling study.

Roy P, Vekemans J, Clark A, Sanderson C, Harris RC, White RG.

Lancet Glob Health. 2019 Dec;7(12):e1655-e1663. doi: 10.1016/S2214-109X(19)30444-9.


GPU-Accelerated Implementation of Continuous Constant pH Molecular Dynamics in Amber: pKa Predictions with Single-pH Simulations.

Harris RC, Shen J.

J Chem Inf Model. 2019 Nov 25;59(11):4821-4832. doi: 10.1021/acs.jcim.9b00754. Epub 2019 Nov 14.


Task-specific adaptations of postural sway in sitting infants.

Arnold AJ, Liddy JJ, Harris RC, Claxton LJ.

Dev Psychobiol. 2020 Jan;62(1):99-106. doi: 10.1002/dev.21910. Epub 2019 Sep 6.


Noninvasive quantitative magnetization transfer MRI reveals tubulointerstitial fibrosis in murine kidney.

Wang F, Wang S, Zhang Y, Li K, Harris RC, Gore JC, Zhang MZ.

NMR Biomed. 2019 Nov;32(11):e4128. doi: 10.1002/nbm.4128. Epub 2019 Jul 29.


The Role of the EGF Receptor in Sex Differences in Kidney Injury.

Zhang MZ, Sasaki K, Li Y, Li Z, Pan Y, Jin GN, Wang Y, Niu A, Wang S, Fan X, Chen JC, Borza C, Yang H, Pozzi A, Fogo AB, Harris RC.

J Am Soc Nephrol. 2019 Sep;30(9):1659-1673. doi: 10.1681/ASN.2018121244. Epub 2019 Jul 10.


The brown fat-secreted adipokine neuregulin 4 is decreased in human and murine chronic kidney disease.

Kralisch S, Hoffmann A, Klöting N, Frille A, Kuhn H, Nowicki M, Paeschke S, Bachmann A, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M, Ebert T.

Eur J Endocrinol. 2019 Aug;181(2):151-159. doi: 10.1530/EJE-19-0017.


Comparative physiology investigations support a role for histidine-containing dipeptides in intracellular acid-base regulation of skeletal muscle.

Dolan E, Saunders B, Harris RC, Bicudo JEPW, Bishop DJ, Sale C, Gualano B.

Comp Biochem Physiol A Mol Integr Physiol. 2019 Aug;234:77-86. doi: 10.1016/j.cbpa.2019.04.017. Epub 2019 Apr 25. Review.


Dynamic signature of lymphangiogenesis during acute kidney injury and chronic kidney disease.

Zarjou A, Black LM, Bolisetty S, Traylor AM, Bowhay SA, Zhang MZ, Harris RC, Agarwal A.

Lab Invest. 2019 Sep;99(9):1376-1388. doi: 10.1038/s41374-019-0259-0. Epub 2019 Apr 24.


Research and development of new tuberculosis vaccines: a review.

Schrager LK, Harris RC, Vekemans J.

Version 2. F1000Res. 2018 Nov 1 [revised 2019 Jan 1];7:1732. doi: 10.12688/f1000research.16521.2. eCollection 2018. Review.


The way forward for tuberculosis vaccines.

White RG, Hanekom WA, Vekemans J, Harris RC.

Lancet Respir Med. 2019 Mar;7(3):204-206. doi: 10.1016/S2213-2600(19)30040-2. No abstract available. Erratum in: Lancet Respir Med. 2019 Apr;7(4):e15.


Age-targeted tuberculosis vaccination in China and implications for vaccine development: a modelling study.

Harris RC, Sumner T, Knight GM, Evans T, Cardenas V, Chen C, White RG.

Lancet Glob Health. 2019 Feb;7(2):e209-e218. doi: 10.1016/S2214-109X(18)30452-2. Epub 2019 Jan 7.


24-Week β-alanine ingestion does not affect muscle taurine or clinical blood parameters in healthy males.

Saunders B, Franchi M, de Oliveira LF, da Eira Silva V, da Silva RP, de Salles Painelli V, Costa LAR, Sale C, Harris RC, Roschel H, Artioli GG, Gualano B.

Eur J Nutr. 2020 Feb;59(1):57-65. doi: 10.1007/s00394-018-1881-0. Epub 2018 Dec 14.


Substrate Elasticity Governs Differentiation of Renal Tubule Cells in Prolonged Culture.

Love HD, Ao M, Jorgensen S, Swearingen L, Ferrell N, Evans R, Gewin L, Harris RC, Zent R, Roy S, Fissell WH.

Tissue Eng Part A. 2019 Jul;25(13-14):1013-1022. doi: 10.1089/ten.TEA.2018.0182. Epub 2019 Jun 14.


Pathological and Transcriptome Changes in the ReninAAV db/ db uNx Model of Advanced Diabetic Kidney Disease Exhibit Features of Human Disease.

Harlan SM, Heinz-Taheny KM, Overstreet JM, Breyer MD, Harris RC, Heuer JG.

Toxicol Pathol. 2018 Dec;46(8):991-998. doi: 10.1177/0192623318804986. Epub 2018 Nov 5.


TGF-β promotes fibrosis after severe acute kidney injury by enhancing renal macrophage infiltration.

Chung S, Overstreet JM, Li Y, Wang Y, Niu A, Wang S, Fan X, Sasaki K, Jin GN, Khodo SN, Gewin L, Zhang MZ, Harris RC.

JCI Insight. 2018 Nov 2;3(21). pii: 123563. doi: 10.1172/jci.insight.123563.


Renal Medullary Interstitial COX-2 (Cyclooxygenase-2) Is Essential in Preventing Salt-Sensitive Hypertension and Maintaining Renal Inner Medulla/Papilla Structural Integrity.

Zhang MZ, Wang S, Wang Y, Zhang Y, Ming Hao C, Harris RC.

Hypertension. 2018 Nov;72(5):1172-1179. doi: 10.1161/HYPERTENSIONAHA.118.11694.


High-Intensity Interval Training Augments Muscle Carnosine in the Absence of Dietary Beta-alanine Intake.

DE Salles Painelli V, Nemezio KM, Pinto AJ, Franchi M, Andrade I, Riani LA, Saunders B, Sale C, Harris RC, Gualano B, Artioli GG.

Med Sci Sports Exerc. 2018 Nov;50(11):2242-2252. doi: 10.1249/MSS.0000000000001697.


CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet.

Zhu L, Luu T, Emfinger CH, Parks BA, Shi J, Trefts E, Zeng F, Kuklenyik Z, Harris RC, Wasserman DH, Fazio S, Stafford JM.

Diabetes. 2018 Dec;67(12):2494-2506. doi: 10.2337/db18-0474. Epub 2018 Sep 13.


A kinetic model of carnosine synthesis in human skeletal muscle.

Spelnikov D, Harris RC.

Amino Acids. 2019 Jan;51(1):115-121. doi: 10.1007/s00726-018-2646-z. Epub 2018 Sep 12.


How Ligand Protonation State Controls Water in Protein-Ligand Binding.

Henderson JA, Harris RC, Tsai CC, Shen J.

J Phys Chem Lett. 2018 Sep 20;9(18):5440-5444. doi: 10.1021/acs.jpclett.8b02440. Epub 2018 Sep 10.


Case Management: An Evolving Role.

Harris RC, Popejoy LL.

West J Nurs Res. 2019 Jan;41(1):3-5. doi: 10.1177/0193945918797601. Epub 2018 Aug 31. No abstract available.


EGF Receptor-Dependent YAP Activation Is Important for Renal Recovery from AKI.

Chen J, You H, Li Y, Xu Y, He Q, Harris RC.

J Am Soc Nephrol. 2018 Sep;29(9):2372-2385. doi: 10.1681/ASN.2017121272. Epub 2018 Aug 2.


Comparison of sustained-release and rapid-release β-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol.

Varanoske AN, Hoffman JR, Church DD, Coker NA, Baker KM, Dodd SJ, Harris RC, Oliveira LP, Dawson VL, Wang R, Fukuda DH, Stout JR.

Amino Acids. 2019 Jan;51(1):49-60. doi: 10.1007/s00726-018-2609-4. Epub 2018 Jul 12.


Inhibition of Epidermal Growth Factor Receptor Activation Is Associated With Improved Diabetic Nephropathy and Insulin Resistance in Type 2 Diabetes.

Li Z, Li Y, Overstreet JM, Chung S, Niu A, Fan X, Wang S, Wang Y, Zhang MZ, Harris RC.

Diabetes. 2018 Sep;67(9):1847-1857. doi: 10.2337/db17-1513. Epub 2018 Jun 29.


Generalized Born Based Continuous Constant pH Molecular Dynamics in Amber: Implementation, Benchmarking and Analysis.

Huang Y, Harris RC, Shen J.

J Chem Inf Model. 2018 Jul 23;58(7):1372-1383. doi: 10.1021/acs.jcim.8b00227. Epub 2018 Jul 11.


ErbB4 deletion predisposes to development of metabolic syndrome in mice.

Zeng F, Wang Y, Kloepfer LA, Wang S, Harris RC.

Am J Physiol Endocrinol Metab. 2018 Oct 1;315(4):E583-E593. doi: 10.1152/ajpendo.00166.2018. Epub 2018 Jun 26.


HIIT Augments Muscle Carnosine in the Absence of Dietary Beta-Alanine Intake.

Salles Painelli V, Nemezio KM, Jéssica A, Franchi M, Andrade I, Riani LA, Saunders B, Sale C, Harris RC, Gualano B, Artioli GG.

Med Sci Sports Exerc. 2018 Jun 21. doi: 10.1249/MSS.0000000000001697. [Epub ahead of print]


Assessment of renal fibrosis in murine diabetic nephropathy using quantitative magnetization transfer MRI.

Wang F, Katagiri D, Li K, Takahashi K, Wang S, Nagasaka S, Li H, Quarles CC, Zhang MZ, Shimizu A, Gore JC, Harris RC, Takahashi T.

Magn Reson Med. 2018 Dec;80(6):2655-2669. doi: 10.1002/mrm.27231. Epub 2018 May 30.


The modifying effect of kidney function on the association of cadmium exposure with blood pressure and cardiovascular mortality: NHANES 1999-2010.

Gao Y, Zhu X, Shrubsole MJ, Fan L, Xia Z, Harris RC, Hou L, Dai Q.

Toxicol Appl Pharmacol. 2018 Aug 15;353:15-22. doi: 10.1016/j.taap.2018.05.032. Epub 2018 May 26.


Imaging mass spectrometry reveals direct albumin fragmentation within the diabetic kidney.

Grove KJ, Lareau NM, Voziyan PA, Zeng F, Harris RC, Hudson BG, Caprioli RM.

Kidney Int. 2018 Aug;94(2):292-302. doi: 10.1016/j.kint.2018.01.040. Epub 2018 May 18.


Fatty acid receptor modulator PBI-4050 inhibits kidney fibrosis and improves glycemic control.

Li Y, Chung S, Li Z, Overstreet JM, Gagnon L, Grouix B, Leduc M, Laurin P, Zhang MZ, Harris RC.

JCI Insight. 2018 May 17;3(10). pii: 120365. doi: 10.1172/jci.insight.120365. eCollection 2018 May 17.


Comparison of the Complication Incidence in Open Versus Endoscopic Gastrocnemius Recession: A Retrospective Medical Record Review.

Harris RC 3rd, Strannigan KL, Piraino J.

J Foot Ankle Surg. 2018 Jul - Aug;57(4):747-752. doi: 10.1053/j.jfas.2018.01.009. Epub 2018 Apr 25.


A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.

Gagnon L, Leduc M, Thibodeau JF, Zhang MZ, Grouix B, Sarra-Bournet F, Gagnon W, Hince K, Tremblay M, Geerts L, Kennedy CRJ, Hébert RL, Gutsol A, Holterman CE, Kamto E, Gervais L, Ouboudinar J, Richard J, Felton A, Laverdure A, Simard JC, Létourneau S, Cloutier MP, Leblond FA, Abbott SD, Penney C, Duceppe JS, Zacharie B, Dupuis J, Calderone A, Nguyen QT, Harris RC, Laurin P.

Am J Pathol. 2018 May;188(5):1132-1148. doi: 10.1016/j.ajpath.2018.01.009. Epub 2018 Feb 16.


Accuracy Comparison of Generalized Born Models in the Calculation of Electrostatic Binding Free Energies.

Izadi S, Harris RC, Fenley MO, Onufriev AV.

J Chem Theory Comput. 2018 Mar 13;14(3):1656-1670. doi: 10.1021/acs.jctc.7b00886. Epub 2018 Feb 15.


Proton-Coupled Conformational Allostery Modulates the Inhibitor Selectivity for β-Secretase.

Harris RC, Tsai CC, Ellis CR, Shen J.

J Phys Chem Lett. 2017 Oct 5;8(19):4832-4837. doi: 10.1021/acs.jpclett.7b02309. Epub 2017 Sep 21.


Comparison of Two β-Alanine Dosing Protocols on Muscle Carnosine Elevations.

Church DD, Hoffman JR, Varanoske AN, Wang R, Baker KM, La Monica MB, Beyer KS, Dodd SJ, Oliveira LP, Harris RC, Fukuda DH, Stout JR.

J Am Coll Nutr. 2017 Nov-Dec;36(8):608-616. doi: 10.1080/07315724.2017.1335250. Epub 2017 Sep 14.


Lysophosphatidic Acid Receptor Antagonism Protects against Diabetic Nephropathy in a Type 2 Diabetic Model.

Zhang MZ, Wang X, Yang H, Fogo AB, Murphy BJ, Kaltenbach R, Cheng P, Zinker B, Harris RC.

J Am Soc Nephrol. 2017 Nov;28(11):3300-3311. doi: 10.1681/ASN.2017010107. Epub 2017 Jul 24.


Assessment of unilateral ureter obstruction with multi-parametric MRI.

Wang F, Takahashi K, Li H, Zu Z, Li K, Xu J, Harris RC, Takahashi T, Gore JC.

Magn Reson Med. 2018 Apr;79(4):2216-2227. doi: 10.1002/mrm.26849. Epub 2017 Jul 24.


ErbB4 deletion accelerates renal fibrosis following renal injury.

Zeng F, Miyazawa T, Kloepfer LA, Harris RC.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F773-F787. doi: 10.1152/ajprenal.00260.2017. Epub 2017 Jul 19.


Tubulointerstitial fibrosis can sensitize the kidney to subsequent glomerular injury.

Lim BJ, Yang JW, Zou J, Zhong J, Matsusaka T, Pastan I, Zhang MZ, Harris RC, Yang HC, Fogo AB.

Kidney Int. 2017 Dec;92(6):1395-1403. doi: 10.1016/j.kint.2017.04.010. Epub 2017 Jul 12.


Blocking TGF-β and β-Catenin Epithelial Crosstalk Exacerbates CKD.

Nlandu-Khodo S, Neelisetty S, Phillips M, Manolopoulou M, Bhave G, May L, Clark PE, Yang H, Fogo AB, Harris RC, Taketo MM, Lee E, Gewin LS.

J Am Soc Nephrol. 2017 Dec;28(12):3490-3503. doi: 10.1681/ASN.2016121351. Epub 2017 Jul 12.


Numerical Difficulties Computing Electrostatic Potentials Near Interfaces with the Poisson-Boltzmann Equation.

Harris RC, Boschitsch AH, Fenley MO.

J Chem Theory Comput. 2017 Aug 8;13(8):3945-3951. doi: 10.1021/acs.jctc.7b00487. Epub 2017 Jul 17.


Selective activation of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis.

Overstreet JM, Wang Y, Wang X, Niu A, Gewin LS, Yao B, Harris RC, Zhang MZ.

FASEB J. 2017 Oct;31(10):4407-4421. doi: 10.1096/fj.201601359RR. Epub 2017 Jun 16.


High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.

Kitada K, Daub S, Zhang Y, Klein JD, Nakano D, Pedchenko T, Lantier L, LaRocque LM, Marton A, Neubert P, Schröder A, Rakova N, Jantsch J, Dikalova AE, Dikalov SI, Harrison DG, Müller DN, Nishiyama A, Rauh M, Harris RC, Luft FC, Wassermann DH, Sands JM, Titze J.

J Clin Invest. 2017 May 1;127(5):1944-1959. doi: 10.1172/JCI88532. Epub 2017 Apr 17.


FSTL3 is increased in renal dysfunction.

Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Stolzenburg JU, Dietel A, Beige J, Anders M, Bast I, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M, Ebert T.

Nephrol Dial Transplant. 2017 Oct 1;32(10):1637-1644. doi: 10.1093/ndt/gfw472.


The novel adipokine/hepatokine fetuin B in severe human and murine diabetic kidney disease.

Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M, Ebert T.

Diabetes Metab. 2017 Oct;43(5):465-468. doi: 10.1016/j.diabet.2017.01.005. Epub 2017 Feb 14. No abstract available.


Twenty-four Weeks of β-Alanine Supplementation on Carnosine Content, Related Genes, and Exercise.

Saunders B, DE Salles Painelli V, DE Oliveira LF, DA Eira Silva V, DA Silva RP, Riani L, Franchi M, Gonçalves LS, Harris RC, Roschel H, Artioli GG, Sale C, Gualano B.

Med Sci Sports Exerc. 2017 May;49(5):896-906. doi: 10.1249/MSS.0000000000001173.


Bright metal coatings from sustainable electrolytes: the effect of molecular additives on electrodeposition of nickel from a deep eutectic solvent.

Abbott AP, Ballantyne A, Harris RC, Juma JA, Ryder KS.

Phys Chem Chem Phys. 2017 Jan 25;19(4):3219-3231. doi: 10.1039/c6cp08720e.


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