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Effect of Vitamin D Supplementation on Markers of Vascular Function: A Systematic Review and Individual Participant Meta-Analysis.

Beveridge LA, Khan F, Struthers AD, Armitage J, Barchetta I, Bressendorff I, Cavallo MG, Clarke R, Dalan R, Dreyer G, Gepner AD, Forouhi NG, Harris RA, Hitman GA, Larsen T, Khadgawat R, Marckmann P, Mose FH, Pilz S, Scholze A, Shargorodsky M, Sokol SI, Stricker H, Zoccali C, Witham MD.

J Am Heart Assoc. 2018 May 30;7(11). pii: e008273. doi: 10.1161/JAHA.117.008273. Review.


Optimizing the Binding Energy of the Surfactant to Iron Oxide Yields Truly Monodisperse Nanoparticles.

Sharifi Dehsari H, Harris RA, Ribeiro AH, Tremel W, Asadi K.

Langmuir. 2018 Jun 5;34(22):6582-6590. doi: 10.1021/acs.langmuir.8b01337. Epub 2018 May 18.


Acute Tetrahydrobiopterin Improves Endothelial Function in Patients With COPD.

Rodriguez-Miguelez P, Gregg J, Seigler N, Bass L, Thomas J, Pollock JS, Sullivan JC, Dillard TA, Harris RA.

Chest. 2018 Apr 26. pii: S0012-3692(18)30653-6. doi: 10.1016/j.chest.2018.04.028. [Epub ahead of print]


Silencing synaptic MicroRNA-411 reduces voluntary alcohol consumption in mice.

Most D, Salem NA, Tiwari GR, Blednov YA, Mayfield RD, Harris RA.

Addict Biol. 2018 Apr 17. doi: 10.1111/adb.12625. [Epub ahead of print]


Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.

Lund H, Pieber M, Parsa R, Grommisch D, Ewing E, Kular L, Han J, Zhu K, Nijssen J, Hedlund E, Needhamsen M, Ruhrmann S, Guerreiro-Cacais AO, Berglund R, Forteza MJ, Ketelhuth DFJ, Butovsky O, Jagodic M, Zhang XM, Harris RA.

Nat Immunol. 2018 May;19(5):1-7. doi: 10.1038/s41590-018-0091-5. Epub 2018 Apr 16.


Oral NaHCO3 Activates a Splenic Anti-Inflammatory Pathway: Evidence That Cholinergic Signals Are Transmitted via Mesothelial Cells.

Ray SC, Baban B, Tucker MA, Seaton AJ, Chang KC, Mannon EC, Sun J, Patel B, Wilson K, Musall JB, Ocasio H, Irsik D, Filosa JA, Sullivan JC, Marshall B, Harris RA, O'Connor PM.

J Immunol. 2018 May 15;200(10):3568-3586. doi: 10.4049/jimmunol.1701605. Epub 2018 Apr 16.


Life after sport: swimming through transitions.

Harris RA.

Med J Aust. 2018 Apr 2;208(6):248-249. No abstract available.


A single high-fat meal provokes pathological erythrocyte remodeling and increases myeloperoxidase levels: implications for acute coronary syndrome.

Benson TW, Weintraub NL, Kim HW, Seigler N, Kumar S, Pye J, Horimatsu T, Pellenberg R, Stepp DW, Lucas R, Bogdanov VY, Litwin SE, Brittain JE, Harris RA.

Lab Invest. 2018 Mar 23. doi: 10.1038/s41374-018-0038-3. [Epub ahead of print]


Predicting short-term interruptions of antiretroviral therapy from summary adherence data: Development and test of a probability model.

Harris RA, Haberer JE, Musinguzi N, Chang KM, Schechter CB, Doubeni CA, Gross R.

PLoS One. 2018 Mar 22;13(3):e0194713. doi: 10.1371/journal.pone.0194713. eCollection 2018.


From gene networks to drugs: systems pharmacology approaches for AUD.

Ferguson LB, Harris RA, Mayfield RD.

Psychopharmacology (Berl). 2018 Jun;235(6):1635-1662. doi: 10.1007/s00213-018-4855-2. Epub 2018 Mar 1. Review.


Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Consumption and Preference.

Blednov YA, Da Costa AJ, Tarbox T, Ponomareva O, Messing RO, Harris RA.

Alcohol Clin Exp Res. 2018 May;42(5):926-938. doi: 10.1111/acer.13616. Epub 2018 Mar 24.


Apremilast Alters Behavioral Responses to Ethanol in Mice: II. Increased Sedation, Intoxication, and Reduced Acute Functional Tolerance.

Blednov YA, Da Costa AJ, Harris RA, Messing RO.

Alcohol Clin Exp Res. 2018 May;42(5):939-951. doi: 10.1111/acer.13615. Epub 2018 Mar 24.


Commentaries on Viewpoint: Principles, insights, and potential pitfalls of the noninvasive determination of muscle oxidative capacity by near-infrared spectroscopy.

Chung S, Nelson MD, Hamaoka T, Jacobs RA, Pearson J, Subudhi AW, Jenkins NT, Bartlett MF, Fitzgerald LF, Miehm JD, Kent JA, Lucero AA, Rowlands DS, Stoner L, McCully KK, Call J, Rodriguez-Miguelez P, Harris RA, Porcelli S, Rasica L, Marzorati M, Quaresima V, Ryan TE, Vernillo G, Millet GP, Malatesta D, Millet GY, Zuo L, Chuang CC.

J Appl Physiol (1985). 2018 Jan 1;124(1):249-255. doi: 10.1152/japplphysiol.00857.2017. No abstract available.


E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells.

Xu S, Tao J, Yang L, Zhang E, Boriboun C, Zhou J, Sun T, Cheng M, Huang K, Shi J, Dong N, Liu Q, Zhao TC, Qiu H, Harris RA, Chandel NS, Losordo DW, Qin G.

Circ Res. 2018 Mar 2;122(5):701-711. doi: 10.1161/CIRCRESAHA.117.311814. Epub 2018 Jan 22.


Determining Double Bond Position in Lipids Using Online Ozonolysis Coupled to Liquid Chromatography and Ion Mobility-Mass Spectrometry.

Harris RA, May JC, Stinson CA, Xia Y, McLean JA.

Anal Chem. 2018 Feb 6;90(3):1915-1924. doi: 10.1021/acs.analchem.7b04007. Epub 2018 Jan 17.


Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain.

Osterndorff-Kahanek EA, Tiwari GR, Lopez MF, Becker HC, Harris RA, Mayfield RD.

PLoS One. 2018 Jan 9;13(1):e0190841. doi: 10.1371/journal.pone.0190841. eCollection 2018.


Astrocyte-specific transcriptome responses to chronic ethanol consumption.

Erickson EK, Farris SP, Blednov YA, Mayfield RD, Harris RA.

Pharmacogenomics J. 2018 Jan 5. doi: 10.1038/s41397-017-0012-2. [Epub ahead of print]


Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host.

Palesch D, Bosinger SE, Tharp GK, Vanderford TH, Paiardini M, Chahroudi A, Johnson ZP, Kirchhoff F, Hahn BH, Norgren RB, Patel NB, Sodora DL, Dawoud RA, Stewart CB, Seepo SM, Harris RA, Liu Y, Raveendran M, Han Y, English A, Thomas GWC, Hahn MW, Pipes L, Mason CE, Muzny DM, Gibbs RA, Sauter D, Worley K, Rogers J, Silvestri G.

Nature. 2018 Jan 3;553(7686):77-81. doi: 10.1038/nature25140.


Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice.

Ferguson LB, Ozburn AR, Ponomarev I, Metten P, Reilly M, Crabbe JC, Harris RA, Mayfield RD.

Neuropsychopharmacology. 2018 May;43(6):1257-1266. doi: 10.1038/npp.2017.301. Epub 2017 Dec 18.


Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus).

Larsen PA, Harris RA, Liu Y, Murali SC, Campbell CR, Brown AD, Sullivan BA, Shelton J, Brown SJ, Raveendran M, Dudchenko O, Machol I, Durand NC, Shamim MS, Aiden EL, Muzny DM, Gibbs RA, Yoder AD, Rogers J, Worley KC.

BMC Biol. 2017 Nov 16;15(1):110. doi: 10.1186/s12915-017-0439-6.


Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies.

Needhamsen M, Ewing E, Lund H, Gomez-Cabrero D, Harris RA, Kular L, Jagodic M.

BMC Bioinformatics. 2017 Nov 15;18(1):486. doi: 10.1186/s12859-017-1870-y.


CFTR Genotype and Maximal Exercise Capacity in Cystic Fibrosis: A Cross-sectional Study.

Radtke T, Hebestreit H, Gallati S, Schneiderman JE, Braun J, Stevens D, Hulzebos EH, Takken T, Boas SR, Urquhart DS, Lands LC, Tejero S, Sovtic A, Dwyer T, Petrovic M, Harris RA, Karila C, Savi D, Usemann J, Mei-Zahav M, Hatziagorou E, Ratjen F, Kriemler S; CFTR-Exercise study group.

Ann Am Thorac Soc. 2018 Feb;15(2):209-216. doi: 10.1513/AnnalsATS.201707-570OC. Epub 2017 Nov 15.


Microglial-specific transcriptome changes following chronic alcohol consumption.

McCarthy GM, Farris SP, Blednov YA, Harris RA, Mayfield RD.

Neuropharmacology. 2018 Jan;128:416-424. doi: 10.1016/j.neuropharm.2017.10.035. Epub 2017 Oct 31.


CNS cell-type localization and LPS response of TLR signaling pathways.

McCarthy GM, Bridges CR, Blednov YA, Harris RA.

F1000Res. 2017 Jul 19;6:1144. doi: 10.12688/f1000research.12036.1. eCollection 2017.


A comparison of best practices for doctoral training in Europe and North America.

Barnett JV, Harris RA, Mulvany MJ.

FEBS Open Bio. 2017 Sep 8;7(10):1444-1452. doi: 10.1002/2211-5463.12305. eCollection 2017 Oct.


Anti-inflammatory (M2) macrophage media reduce transmission of oligomeric amyloid beta in differentiated SH-SY5Y cells.

Sackmann V, Ansell A, Sackmann C, Lund H, Harris RA, Hallbeck M, Nilsberth C.

Neurobiol Aging. 2017 Dec;60:173-182. doi: 10.1016/j.neurobiolaging.2017.08.022. Epub 2017 Sep 1.


Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance.

Tarvin RD, Borghese CM, Sachs W, Santos JC, Lu Y, O'Connell LA, Cannatella DC, Harris RA, Zakon HH.

Science. 2017 Sep 22;357(6357):1261-1266. doi: 10.1126/science.aan5061.


Blood flow regulation and oxidative stress during submaximal cycling exercise in patients with cystic fibrosis.

Tucker MA, Berry B, Seigler N, Davison GW, Quindry JC, Eidson D, McKie KT, Harris RA.

J Cyst Fibros. 2018 Mar;17(2):256-263. doi: 10.1016/j.jcf.2017.08.015. Epub 2017 Oct 12.


Chronic ethanol consumption: role of TLR3/TRIF-dependent signaling.

McCarthy GM, Warden AS, Bridges CR, Blednov YA, Harris RA.

Addict Biol. 2018 May;23(3):889-903. doi: 10.1111/adb.12539. Epub 2017 Aug 25.


Scavenger Receptor A Mediates the Clearance and Immunological Screening of MDA-Modified Antigen by M2-Type Macrophages.

Warnecke A, Abele S, Musunuri S, Bergquist J, Harris RA.

Neuromolecular Med. 2017 Dec;19(4):463-479. doi: 10.1007/s12017-017-8461-y. Epub 2017 Aug 21.


Lessons Learned about Neurodegeneration from Microglia and Monocyte Depletion Studies.

Lund H, Pieber M, Harris RA.

Front Aging Neurosci. 2017 Jul 28;9:234. doi: 10.3389/fnagi.2017.00234. eCollection 2017. Review.


Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain.

McCracken LM, Lowes DC, Salling MC, Carreau-Vollmer C, Odean NN, Blednov YA, Betz H, Harris RA, Harrison NL.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7179-E7186. doi: 10.1073/pnas.1703839114. Epub 2017 Aug 7.


Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes.

Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B.

Sci Rep. 2017 Jul 24;7(1):6230. doi: 10.1038/s41598-017-05966-x.


A single bout of maximal exercise improves lung function in patients with cystic fibrosis.

Tucker MA, Crandall R, Seigler N, Rodriguez-Miguelez P, McKie KT, Forseen C, Thomas J, Harris RA.

J Cyst Fibros. 2017 Nov;16(6):752-758. doi: 10.1016/j.jcf.2017.05.011. Epub 2017 Jun 23.


The future is now: A 2020 view of alcoholism research.

Harris RA, Koob GF.

Neuropharmacology. 2017 Aug 1;122:1-2. doi: 10.1016/j.neuropharm.2017.06.001. No abstract available.


An updated assessment of microglia depletion: current concepts and future directions.

Han J, Harris RA, Zhang XM.

Mol Brain. 2017 Jun 19;10(1):25. doi: 10.1186/s13041-017-0307-x. Review.


Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress.

Yang T, Zhang XM, Tarnawski L, Peleli M, Zhuge Z, Terrando N, Harris RA, Olofsson PS, Larsson E, Persson AEG, Lundberg JO, Weitzberg E, Carlstrom M.

Redox Biol. 2017 Oct;13:320-330. doi: 10.1016/j.redox.2017.06.002. Epub 2017 Jun 9.


Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination.

Blednov YA, Borghese CM, Ruiz CI, Cullins MA, Da Costa A, Osterndorff-Kahanek EA, Homanics GE, Harris RA.

Neuropharmacology. 2017 Sep 1;123:201-209. doi: 10.1016/j.neuropharm.2017.06.013. Epub 2017 Jun 13.


Mechanistic insights into epigenetic modulation of ethanol consumption.

Ponomarev I, Stelly CE, Morikawa H, Blednov YA, Mayfield RD, Harris RA.

Alcohol. 2017 May;60:95-101. doi: 10.1016/j.alcohol.2017.01.016. Epub 2017 Mar 12.


Flavored e-cigarette liquids reduce proliferation and viability in the CALU3 airway epithelial cell line.

Rowell TR, Reeber SL, Lee SL, Harris RA, Nethery RC, Herring AH, Glish GL, Tarran R.

Am J Physiol Lung Cell Mol Physiol. 2017 Jul 1;313(1):L52-L66. doi: 10.1152/ajplung.00392.2016. Epub 2017 Apr 20.


Rebuttal from Paula Rodriguez-Miguelez, Melissa L. Erickson, Kevin K. McCully and Ryan A. Harris.

Rodriguez-Miguelez P, Erickson ML, McCully KK, Harris RA.

J Physiol. 2017 Mar 1;595(5):1429. doi: 10.1113/JP273738. No abstract available.


CrossTalk proposal: Skeletal muscle oxidative capacity is altered in patients with cystic fibrosis.

Rodriguez-Miguelez P, Erickson ML, McCully KK, Harris RA.

J Physiol. 2017 Mar 1;595(5):1423-1425. doi: 10.1113/JP272486. No abstract available.


Standardization of a Videofluoroscopic Swallow Study Protocol to Investigate Dysphagia in Dogs.

Harris RA, Grobman ME, Allen MJ, Schachtel J, Rawson NE, Bennett B, Ledyayev J, Hopewell B, Coates JR, Reinero CR, Lever TE.

J Vet Intern Med. 2017 Mar;31(2):383-393. doi: 10.1111/jvim.14676. Epub 2017 Feb 27.


3D printed fluidics with embedded analytic functionality for automated reaction optimisation.

Capel AJ, Wright A, Harding MJ, Weaver GW, Li Y, Harris RA, Edmondson S, Goodridge RD, Christie SD.

Beilstein J Org Chem. 2017 Jan 18;13:111-119. doi: 10.3762/bjoc.13.14. eCollection 2017.


Sedative and Motor Incoordination Effects of Ethanol in Mice Lacking CD14, TLR2, TLR4, or MyD88.

Blednov YA, Black M, Benavidez JM, Da Costa A, Mayfield J, Harris RA.

Alcohol Clin Exp Res. 2017 Mar;41(3):531-540. doi: 10.1111/acer.13314. Epub 2017 Feb 3.


Ethanol Consumption in Mice Lacking CD14, TLR2, TLR4, or MyD88.

Blednov YA, Black M, Chernis J, Da Costa A, Mayfield J, Harris RA.

Alcohol Clin Exp Res. 2017 Mar;41(3):516-530. doi: 10.1111/acer.13316. Epub 2017 Feb 1.


Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication.

Aagaard KM, Lahon A, Suter MA, Arya RP, Seferovic MD, Vogt MB, Hu M, Stossi F, Mancini MA, Harris RA, Kahr M, Eppes C, Rac M, Belfort MA, Park CS, Lacorazza D, Rico-Hesse R.

Sci Rep. 2017 Jan 27;7:41389. doi: 10.1038/srep41389.


Melatonin ameliorates alcohol-induced bile acid synthesis by enhancing miR-497 expression.

Kim YD, Hwang SL, Lee EJ, Kim HM, Chung MJ, Elfadl AK, Lee SE, Nedumaran B, Harris RA, Jeong KS.

J Pineal Res. 2017 Mar;62(2). doi: 10.1111/jpi.12386. Epub 2017 Feb 10.


Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury.

Oh CJ, Ha CM, Choi YK, Park S, Choe MS, Jeoung NH, Huh YH, Kim HJ, Kweon HS, Lee JM, Lee SJ, Jeon JH, Harris RA, Park KG, Lee IK.

Kidney Int. 2017 Apr;91(4):880-895. doi: 10.1016/j.kint.2016.10.011. Epub 2016 Dec 28.


Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype.

Warnecke A, Musunuri S, N'diaye M, Sandalova T, Achour A, Bergquist J, Harris RA.

J Neuroimmunol. 2017 Feb 15;303:1-12. doi: 10.1016/j.jneuroim.2016.11.008. Epub 2016 Nov 26.

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