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Items: 1 to 50 of 68

1.

The role of insulin-like growth factor 2 receptor-mediated homeobox gene expression in human placental apoptosis, and its implications in idiopathic fetal growth restriction.

Harris LK, Pantham P, Yong HEJ, Pratt A, Borg AJ, Crocker I, Westwood M, Aplin J, Kalionis B, Murthi P.

Mol Hum Reprod. 2019 Aug 16. pii: gaz047. doi: 10.1093/molehr/gaz047. [Epub ahead of print]

PMID:
31418778
2.

Placental bed research: 2. Functional and immunological investigations of the placental bed.

Harris LK, Benagiano M, D'Elios MM, Brosens I, Benagiano G.

Am J Obstet Gynecol. 2019 Jul 6. pii: S0002-9378(19)30894-4. doi: 10.1016/j.ajog.2019.07.010. [Epub ahead of print]

PMID:
31288009
3.

Identification and prioritization of macrolideresistance genes with hypothetical annotation inStreptococcus pneumoniae.

Goad B, Harris LK.

Bioinformation. 2018 Dec 9;14(9):488-498. doi: 10.6026/97320630014488. eCollection 2018.

4.

IGF signalling and endocytosis in the human villous placenta in early pregnancy as revealed by comparing quantum dot conjugates with a soluble ligand.

Karolczak-Bayatti M, Forbes K, Horn J, Teesalu T, Harris LK, Westwood M, Aplin JD.

Nanoscale. 2019 Jun 27;11(25):12285-12295. doi: 10.1039/c8nr10337b.

PMID:
31211316
5.

Failure of Decidualization and Maternal Immune Tolerance Underlies Uterovascular Resistance in Intra Uterine Growth Restriction.

Dunk C, Kwan M, Hazan A, Walker S, Wright JK, Harris LK, Jones RL, Keating S, Kingdom JCP, Whittle W, Maxwell C, Lye SJ.

Front Endocrinol (Lausanne). 2019 Mar 20;10:160. doi: 10.3389/fendo.2019.00160. eCollection 2019.

6.

The use of tail-anchored protein chimeras to enhance liposomal cargo delivery.

Abdelrehim A, Shaltiel L, Zhang L, Barenholz Y, High S, Harris LK.

PLoS One. 2019 Feb 22;14(2):e0212701. doi: 10.1371/journal.pone.0212701. eCollection 2019.

7.

Decidual leucocytes infiltrating human spiral arterioles are rich source of matrix metalloproteinases and degrade extracellular matrix in vitro and in situ.

Choudhury RH, Dunk CE, Lye SJ, Harris LK, Aplin JD, Jones RL.

Am J Reprod Immunol. 2019 Jan;81(1):e13054. doi: 10.1111/aji.13054. Epub 2018 Sep 29.

PMID:
30267451
8.

Surface Area to Volume Ratio: A Natural Variable for Bacterial Morphogenesis.

Harris LK, Theriot JA.

Trends Microbiol. 2018 Oct;26(10):815-832. doi: 10.1016/j.tim.2018.04.008. Epub 2018 May 26.

9.

Dog Theft: A Case for Tougher Sentencing Legislation.

Harris LK.

Animals (Basel). 2018 May 22;8(5). pii: E78. doi: 10.3390/ani8050078. Review.

10.

An investigation of mechanical nociceptive thresholds in dogs with hind limb joint pain compared to healthy control dogs.

Harris LK, Whay HR, Murrell JC.

Vet J. 2018 Apr;234:85-90. doi: 10.1016/j.tvjl.2017.12.012. Epub 2017 Dec 15.

PMID:
29680400
11.

Delineating differential regulatory signatures of the human transcriptome in the choriodecidua and myometrium at term labor.

Lui S, Duval C, Farrokhnia F, Girard S, Harris LK, Tower CL, Stevens A, Jones RL.

Biol Reprod. 2018 Mar 1;98(3):422-436. doi: 10.1093/biolre/iox186.

PMID:
29329366
12.

Selective Targeting of a Novel Vasodilator to the Uterine Vasculature to Treat Impaired Uteroplacental Perfusion in Pregnancy.

Cureton N, Korotkova I, Baker B, Greenwood S, Wareing M, Kotamraju VR, Teesalu T, Cellesi F, Tirelli N, Ruoslahti E, Aplin JD, Harris LK.

Theranostics. 2017 Aug 29;7(15):3715-3731. doi: 10.7150/thno.19678. eCollection 2017.

13.

Placental Homing Peptide-microRNA Inhibitor Conjugates for Targeted Enhancement of Intrinsic Placental Growth Signaling.

Beards F, Jones LE, Charnock J, Forbes K, Harris LK.

Theranostics. 2017 Jul 14;7(11):2940-2955. doi: 10.7150/thno.18845. eCollection 2017.

14.

Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation.

Novakovic B, Fournier T, Harris LK, James J, Roberts CT, Yong HEJ, Kalionis B, Evain-Brion D, Ebeling PR, Wallace EM, Saffery R, Murthi P.

Sci Rep. 2017 Jul 3;7(1):4523. doi: 10.1038/s41598-017-04776-5.

15.

Improved Annotations of 23 Differentially Expressed Hypothetical Proteins in Methicillin Resistant S.aureus.

Marklevitz J, Harris LK.

Bioinformation. 2017 Apr 30;13(4):104-110. doi: 10.6026/97320630013104. eCollection 2017.

16.

Extravillous Trophoblast and Endothelial Cell Crosstalk Mediates Leukocyte Infiltration to the Early Remodeling Decidual Spiral Arteriole Wall.

Choudhury RH, Dunk CE, Lye SJ, Aplin JD, Harris LK, Jones RL.

J Immunol. 2017 May 15;198(10):4115-4128. doi: 10.4049/jimmunol.1601175. Epub 2017 Apr 10.

17.

Characterization of TPP-binding proteins in Methanococci archaeal species.

Harris LK.

Bioinformation. 2016 Nov 22;12(8):359-367. doi: 10.6026/97320630012359. eCollection 2016.

18.

Prediction driven functional annotation of hypothetical proteins in the major facilitator superfamily of S. aureus NCTC 8325.

Marklevitz J, Harris LK.

Bioinformation. 2016 Jul 26;12(4):254-262. doi: 10.6026/97320630012254. eCollection 2016.

19.

Could peptide-decorated nanoparticles provide an improved approach for treating pregnancy complications?

Harris LK.

Nanomedicine (Lond). 2016 Sep;11(17):2235-8. doi: 10.2217/nnm-2016-0234. Epub 2016 Aug 4. No abstract available.

20.

Tumor-homing peptides as tools for targeted delivery of payloads to the placenta.

King A, Ndifon C, Lui S, Widdows K, Kotamraju VR, Agemy L, Teesalu T, Glazier JD, Cellesi F, Tirelli N, Aplin JD, Ruoslahti E, Harris LK.

Sci Adv. 2016 May 6;2(5):e1600349. doi: 10.1126/sciadv.1600349. eCollection 2016 May.

21.

Relative Rates of Surface and Volume Synthesis Set Bacterial Cell Size.

Harris LK, Theriot JA.

Cell. 2016 Jun 2;165(6):1479-1492. doi: 10.1016/j.cell.2016.05.045.

22.

Changes in vascular extracellular matrix composition during decidual spiral arteriole remodeling in early human pregnancy.

Smith SD, Choudhury RH, Matos P, Horn JA, Lye SJ, Dunk CE, Aplin JD, Jones RL, Harris LK.

Histol Histopathol. 2016 May;31(5):557-71. doi: 10.14670/HH-11-696. Epub 2015 Nov 25.

PMID:
26602431
23.

Human dNK cell function is differentially regulated by extrinsic cellular engagement and intrinsic activating receptors in first and second trimester pregnancy.

Zhang J, Dunk CE, Kwan M, Jones RL, Harris LK, Keating S, Lye SJ.

Cell Mol Immunol. 2017 Feb;14(2):203-213. doi: 10.1038/cmi.2015.66. Epub 2015 Aug 17.

24.

Influence of experimental protocol on response rate and repeatability of mechanical threshold testing in dogs.

Harris LK, Murrell JC, van Klink EG, Whay HR.

Vet J. 2015 Apr;204(1):82-7. doi: 10.1016/j.tvjl.2015.02.008. Epub 2015 Feb 10.

25.

Dynamic changes in maternal decidual leukocyte populations from first to second trimester gestation.

Kwan M, Hazan A, Zhang J, Jones RL, Harris LK, Whittle W, Keating S, Dunk CE, Lye SJ.

Placenta. 2014 Dec;35(12):1027-34. doi: 10.1016/j.placenta.2014.09.018. Epub 2014 Oct 6.

PMID:
25449030
26.

Transcriptomic profiling of human choriodecidua during term labor: inflammation as a key driver of labor.

Stephen GL, Lui S, Hamilton SA, Tower CL, Harris LK, Stevens A, Jones RL.

Am J Reprod Immunol. 2015 Jan;73(1):36-55. doi: 10.1111/aji.12328. Epub 2014 Oct 4.

PMID:
25283845
27.

A Caulobacter MreB mutant with irregular cell shape exhibits compensatory widening to maintain a preferred surface area to volume ratio.

Harris LK, Dye NA, Theriot JA.

Mol Microbiol. 2014 Sep 30. doi: 10.1111/mmi.12811. [Epub ahead of print]

28.

Elastin-derived peptides stimulate trophoblast migration and invasion: a positive feedback loop to enhance spiral artery remodelling.

Desforges M, Harris LK, Aplin JD.

Mol Hum Reprod. 2015 Jan;21(1):95-104. doi: 10.1093/molehr/gau089. Epub 2014 Sep 22.

PMID:
25245255
29.

A role for the mitochondrial-associated protein p32 in regulation of trophoblast proliferation.

Matos P, Horn JA, Beards F, Lui S, Desforges M, Harris LK.

Mol Hum Reprod. 2014 Aug;20(8):745-55. doi: 10.1093/molehr/gau039. Epub 2014 May 29.

30.

A general assay for monitoring the activities of protein tyrosine phosphatases in living eukaryotic cells.

Harris LK, Frumm SM, Bishop AC.

Anal Biochem. 2013 Apr 15;435(2):99-105. doi: 10.1016/j.ab.2012.12.025. Epub 2013 Jan 16.

31.

Uterine natural killer cells initiate spiral artery remodeling in human pregnancy.

Robson A, Harris LK, Innes BA, Lash GE, Aljunaidy MM, Aplin JD, Baker PN, Robson SC, Bulmer JN.

FASEB J. 2012 Dec;26(12):4876-85. doi: 10.1096/fj.12-210310. Epub 2012 Aug 23.

PMID:
22919072
32.

Development of novel single-stranded nucleic acid aptamers against the pro-angiogenic and metastatic enzyme heparanase (HPSE1).

Simmons SC, McKenzie EA, Harris LK, Aplin JD, Brenchley PE, Velasco-Garcia MN, Missailidis S.

PLoS One. 2012;7(6):e37938. doi: 10.1371/journal.pone.0037938. Epub 2012 Jun 15. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/48b14416-bb2e-422f-89db-cf7f81df61aa.

33.

Biology and significance of signalling pathways activated by IGF-II.

Harris LK, Westwood M.

Growth Factors. 2012 Feb;30(1):1-12. doi: 10.3109/08977194.2011.640325. Epub 2011 Dec 5. Review.

PMID:
22136428
34.

IFPA Meeting 2010 Workshop Report I: Immunology; ion transport; epigenetics; vascular reactivity; epitheliochorial placentation; proteomics.

Abad C, Antczak DF, Carvalho J, Chamley LW, Chen Q, Daher S, Damiano AE, Dantzer V, Díaz P, Dunk CE, Daly E, Escudero C, Falcón B, Guillomot M, Han YW, Harris LK, Huidobro-Toro JP, Illsley N, Jammes H, Jansson T, Johnson GA, Kfoury JR Jr, Marín R, Murthi P, Novakovic B, Myatt L, Petroff MG, Pereira FT, Pfarrer C, Redman CW, Rice G, Saffery R, Tolosa JM, Vaillancourt C, Wareing M, Yuen R, Lash GE.

Placenta. 2011 Mar;32 Suppl 2:S81-9. doi: 10.1016/j.placenta.2010.12.019. Epub 2011 Jan 12.

PMID:
21227506
35.

IFPA Gabor Than Award lecture: Transformation of the spiral arteries in human pregnancy: key events in the remodelling timeline.

Harris LK.

Placenta. 2011 Mar;32 Suppl 2:S154-8. doi: 10.1016/j.placenta.2010.11.018. Epub 2010 Dec 16.

PMID:
21167598
36.

IGF2 actions on trophoblast in human placenta are regulated by the insulin-like growth factor 2 receptor, which can function as both a signaling and clearance receptor.

Harris LK, Crocker IP, Baker PN, Aplin JD, Westwood M.

Biol Reprod. 2011 Mar;84(3):440-6. doi: 10.1095/biolreprod.110.088195. Epub 2010 Oct 27.

37.

Trophoblast- and vascular smooth muscle cell-derived MMP-12 mediates elastolysis during uterine spiral artery remodeling.

Harris LK, Smith SD, Keogh RJ, Jones RL, Baker PN, Knöfler M, Cartwright JE, Whitley GS, Aplin JD.

Am J Pathol. 2010 Oct;177(4):2103-15. doi: 10.2353/ajpath.2010.100182. Epub 2010 Aug 27.

38.

Review: Trophoblast-vascular cell interactions in early pregnancy: how to remodel a vessel.

Harris LK.

Placenta. 2010 Mar;31 Suppl:S93-8. doi: 10.1016/j.placenta.2009.12.012. Epub 2010 Jan 8. Review.

PMID:
20060584
39.

Plasma from women with preeclampsia inhibits trophoblast invasion.

Harris LK, Clancy OH, Myers JE, Baker PN.

Reprod Sci. 2009 Nov;16(11):1082-90. doi: 10.1177/1933719109341842. Epub 2009 Aug 5.

PMID:
19657139
40.

Evidence for immune cell involvement in decidual spiral arteriole remodeling in early human pregnancy.

Smith SD, Dunk CE, Aplin JD, Harris LK, Jones RL.

Am J Pathol. 2009 May;174(5):1959-71. doi: 10.2353/ajpath.2009.080995. Epub 2009 Apr 6.

41.

Adhesion molecules in human trophoblast - a review. I. Villous trophoblast.

Aplin JD, Jones CJ, Harris LK.

Placenta. 2009 Apr;30(4):293-8. doi: 10.1016/j.placenta.2008.12.001. Epub 2009 Jan 7. Review.

PMID:
19131106
42.

Adhesion molecules in human trophoblast - a review. II. extravillous trophoblast.

Harris LK, Jones CJ, Aplin JD.

Placenta. 2009 Apr;30(4):299-304. doi: 10.1016/j.placenta.2008.12.003. Epub 2009 Jan 7. Review.

PMID:
19131105
43.

The effect of chromosome geometry on genetic diversity.

Marri PR, Harris LK, Houmiel K, Slater SC, Ochman H.

Genetics. 2008 May;179(1):511-6. doi: 10.1534/genetics.107.085621.

44.

S-nitrosylation of proteins at the leading edge of migrating trophoblasts by inducible nitric oxide synthase promotes trophoblast invasion.

Harris LK, McCormick J, Cartwright JE, Whitley GS, Dash PR.

Exp Cell Res. 2008 May 1;314(8):1765-76. doi: 10.1016/j.yexcr.2008.02.010. Epub 2008 Feb 29.

PMID:
18394602
45.

Trophoblast-derived heparanase is not required for invasion.

Harris LK, Baker PN, Brenchley PE, Aplin JD.

Placenta. 2008 Apr;29(4):332-7. doi: 10.1016/j.placenta.2008.01.012. Epub 2008 Mar 10.

PMID:
18329709
46.

Vascular remodeling and extracellular matrix breakdown in the uterine spiral arteries during pregnancy.

Harris LK, Aplin JD.

Reprod Sci. 2007 Dec;14(8 Suppl):28-34. doi: 10.1177/1933719107309588. Review.

PMID:
18089607
47.

Regulation of trophoblast invasion - a workshop report.

Knöfler M, Simmons DG, Lash GE, Harris LK, Armant DR.

Placenta. 2008 Mar;29 Suppl A:S26-8. Epub 2008 Feb 20.

48.

A re-appraisal of the morphophenotype and basal lamina coverage of cytotrophoblasts in human term placenta.

Jones CJ, Harris LK, Whittingham J, Aplin JD, Mayhew TM.

Placenta. 2008 Feb;29(2):215-9. Epub 2007 Dec 20.

PMID:
18082881
49.

BeWo cells stimulate smooth muscle cell apoptosis and elastin breakdown in a model of spiral artery transformation.

Harris LK, Keogh RJ, Wareing M, Baker PN, Cartwright JE, Whitley GS, Aplin JD.

Hum Reprod. 2007 Nov;22(11):2834-41. Epub 2007 Sep 27.

PMID:
17905750
50.

Mechanism of the antioxidant to pro-oxidant switch in the behavior of dehydroascorbate during LDL oxidation by copper(II) ions.

Horsley ET, Burkitt MJ, Jones CM, Patterson RA, Harris LK, Moss NJ, del Rio JD, Leake DS.

Arch Biochem Biophys. 2007 Sep 15;465(2):303-14. Epub 2007 Jul 14.

PMID:
17689484

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