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Items: 1 to 50 of 229

1.

A Panel of Protein Kinase Chemosensors Distinguishes Different Types of Fatty Liver Disease.

Beck JR, Cabral F, Rasineni K, Casey CA, Harris EN, Stains CI.

Biochemistry. 2019 Sep 17;58(37):3911-3917. doi: 10.1021/acs.biochem.9b00547. Epub 2019 Aug 29.

PMID:
31433166
2.

Ligand Binding and Signaling of HARE/Stabilin-2.

Harris EN, Cabral F.

Biomolecules. 2019 Jul 11;9(7). pii: E273. doi: 10.3390/biom9070273. Review.

3.

Sex Differences in the Reward-Enhancing Effects of Nicotine on Ethanol Reinforcement: A Reinforcer Demand Analysis.

Barrett ST, Thompson BM, Emory JR, Larsen CE, Pittenger ST, Harris EN, Bevins RA.

Nicotine Tob Res. 2019 Apr 15. pii: ntz056. doi: 10.1093/ntr/ntz056. [Epub ahead of print]

PMID:
30982885
4.

Chronic alcohol exposure alters circulating insulin and ghrelin levels: role of ghrelin in hepatic steatosis.

Rasineni K, Thomes PG, Kubik JL, Harris EN, Kharbanda KK, Casey CA.

Am J Physiol Gastrointest Liver Physiol. 2019 Apr 1;316(4):G453-G461. doi: 10.1152/ajpgi.00334.2018. Epub 2019 Jan 31.

PMID:
30702902
5.

Effect of nanoformulated copper/zinc superoxide dismutase on chronic ethanol-induced alterations in liver and adipose tissue.

Natarajan G, Perriotte-Olson C, Casey CA, Donohue TM Jr, Talmon GA, Harris EN, Kabanov AV, Saraswathi V.

Alcohol. 2019 Sep;79:71-79. doi: 10.1016/j.alcohol.2018.12.005. Epub 2019 Jan 3.

PMID:
30611703
6.

Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1.

Pirie E, Ray S, Pan C, Fu W, Powers AF, Polikoff D, Miller CM, Kudrna KM, Harris EN, Lusis AJ, Crooke RM, Lee RG.

PLoS Genet. 2018 Oct 29;14(10):e1007732. doi: 10.1371/journal.pgen.1007732. eCollection 2018 Oct.

7.

Single-Molecule Unbinding Forces between the Polysaccharide Hyaluronan and Its Binding Proteins.

Bano F, Tammi MI, Kang DW, Harris EN, Richter RP.

Biophys J. 2018 Jun 19;114(12):2910-2922. doi: 10.1016/j.bpj.2018.05.014.

8.

3-O sulfation of heparin leads to hepatotropism and longer circulatory half-life.

Miller CM, Xu Y, Kudrna KM, Hass BE, Kellar BM, Egger AW, Liu J, Harris EN.

Thromb Res. 2018 Jul;167:80-87. doi: 10.1016/j.thromres.2018.05.018. Epub 2018 May 17.

9.

A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors.

Srivastava T, Diba P, Dean JM, Banine F, Shaver D, Hagen M, Gong X, Su W, Emery B, Marks DL, Harris EN, Baggenstoss B, Weigel PH, Sherman LS, Back SA.

J Clin Invest. 2018 May 1;128(5):2025-2041. doi: 10.1172/JCI94158. Epub 2018 Apr 16.

10.

Structural Determinants for the Interactions of Chemically Modified Nucleic Acids with the Stabilin-2 Clearance Receptor.

Gaus H, Miller CM, Seth PP, Harris EN.

Biochemistry. 2018 Apr 10;57(14):2061-2064. doi: 10.1021/acs.biochem.8b00126. Epub 2018 Mar 30.

11.

Purification of Hepatocytes and Sinusoidal Endothelial Cells from Mouse Liver Perfusion.

Cabral F, Miller CM, Kudrna KM, Hass BE, Daubendiek JG, Kellar BM, Harris EN.

J Vis Exp. 2018 Feb 12;(132). doi: 10.3791/56993.

12.

Performance Evaluation and Clinical Associations of Immunoassays That Detect Antibodies to Negatively Charged Phospholipids Other Than Cardiolipin.

Castanon A, Pierre G, Willis R, Harris EN, Papalardo E, Romay-Penabad Z, Schleh A, Jajoria P, Smikle M, DeCeulaer K, Tebo A, Jaskowski T, Guerra MM, Branch DW, Salmon JE, Petri M, Gonzalez EB.

Am J Clin Pathol. 2018 Mar 29;149(5):401-411. doi: 10.1093/ajcp/aqy003.

13.

Endosomal Escape of Antisense Oligonucleotides Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation.

Miller CM, Wan WB, Seth PP, Harris EN.

Nucleic Acid Ther. 2018 Apr;28(2):86-96. doi: 10.1089/nat.2017.0694. Epub 2018 Feb 13.

14.

Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver.

Miller CM, Tanowitz M, Donner AJ, Prakash TP, Swayze EE, Harris EN, Seth PP.

Nucleic Acid Ther. 2018 Jun;28(3):119-127. doi: 10.1089/nat.2017.0709. Epub 2018 Feb 9. Review.

15.

Quantification of Cell Signaling Networks Using Kinase Activity Chemosensors.

Beck JR, Harris EN, Stains CI.

Methods Mol Biol. 2017;1636:61-70. doi: 10.1007/978-1-4939-7154-1_4.

16.

Longterm Outcome of Patients with Primary Antiphospholipid Syndrome: A Retrospective Multicenter Study.

Taraborelli M, Reggia R, Dall'Ara F, Fredi M, Andreoli L, Gerosa M, Hoxha A, Massaro L, Tonello M, Costedoat-Chalumeau N, Cacoub P, Franceschini F, Meroni PL, Piette JC, Ruffatti A, Valesini G, Harris EN, Tincani A.

J Rheumatol. 2017 Aug;44(8):1165-1172. doi: 10.3899/jrheum.161364. Epub 2017 Jun 1.

PMID:
28572466
17.

Educational Health Disparities in Cardiovascular Disease Risk Factors: Findings from Jamaica Health and Lifestyle Survey 2007-2008.

Ferguson TS, Younger-Coleman NOM, Tulloch-Reid MK, Hambleton IR, Francis DK, Bennett NR, McFarlane SR, Bidulescu A, MacLeish MY, Hennis AJM, Wilks RJ, Harris EN, Sullivan LW.

Front Cardiovasc Med. 2017 May 15;4:28. doi: 10.3389/fcvm.2017.00028. eCollection 2017.

18.

Social determinants of breast cancer in the Caribbean: a systematic review.

Brown CR, Hambleton IR, Hercules SM, Alvarado M, Unwin N, Murphy MM, Harris EN, Wilks R, MacLeish M, Sullivan L, Sobers-Grannum N; U.S. Caribbean Alliance for Health Disparities Research Group (USCAHDR).

Int J Equity Health. 2017 Apr 5;16(1):60. doi: 10.1186/s12939-017-0540-z. Review.

19.

SECs (Sinusoidal Endothelial Cells), Liver Microenvironment, and Fibrosis.

Natarajan V, Harris EN, Kidambi S.

Biomed Res Int. 2017;2017:4097205. doi: 10.1155/2017/4097205. Epub 2017 Feb 15. Review.

20.

Educational health disparities in hypertension and diabetes mellitus among African descent populations in the Caribbean and the USA: a comparative analysis from the Spanish town cohort (Jamaica) and the Jackson heart study (USA).

Bidulescu A, Ferguson TS, Hambleton I, Younger-Coleman N, Francis D, Bennett N, Griswold M, Fox E, MacLeish M, Wilks R, Harris EN, Sullivan LW.

Int J Equity Health. 2017 Feb 14;16(1):33. doi: 10.1186/s12939-017-0527-9.

21.

A unique antiphospholipid assay recognizing phospholipid mixture compared with criteria antiphospholipid immunoassays in lupus patients.

Zuo Y, Willis R, Papalardo E, Petri M, Harris EN, Schleh A, DeCeulaer K, Smikle M, Vilá LM, Reveille JD, Alarcón GS, Gonzalez EB.

Lupus. 2017 May;26(6):606-615. doi: 10.1177/0961203316671812. Epub 2016 Oct 16.

PMID:
27753626
22.

Hyaluronan synthase control of synthesis rate and hyaluronan product size are independent functions differentially affected by mutations in a conserved tandem B-X7-B motif.

Baggenstoss BA, Harris EN, Washburn JL, Medina AP, Nguyen L, Weigel PH.

Glycobiology. 2017 Jan;27(2):154-164. doi: 10.1093/glycob/cww089. Epub 2016 Aug 24.

23.

Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs.

Pandey MS, Miller CM, Harris EN, Weigel PH.

PLoS One. 2016 Apr 21;11(4):e0154124. doi: 10.1371/journal.pone.0154124. eCollection 2016.

24.

Antibodies to Phosphatidylserine/Prothrombin Complex in Antiphospholipid Syndrome: Analytical and Clinical Perspectives.

Peterson LK, Willis R, Harris EN, Branch WD, Tebo AE.

Adv Clin Chem. 2016;73:1-28. doi: 10.1016/bs.acc.2015.10.003. Epub 2016 Jan 13. Review.

PMID:
26975968
25.

Alcoholic vs non-alcoholic fatty liver in rats: distinct differences in endocytosis and vesicle trafficking despite similar pathology.

Rasineni K, Penrice DD, Natarajan SK, McNiven MA, McVicker BL, Kharbanda KK, Casey CA, Harris EN.

BMC Gastroenterol. 2016 Feb 29;16:27. doi: 10.1186/s12876-016-0433-4.

26.

Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver.

Miller CM, Donner AJ, Blank EE, Egger AW, Kellar BM, Østergaard ME, Seth PP, Harris EN.

Nucleic Acids Res. 2016 Apr 7;44(6):2782-94. doi: 10.1093/nar/gkw112. Epub 2016 Feb 22.

27.

Antisense Oligonucleotides: Treatment Strategies and Cellular Internalization.

Miller CM, Harris EN.

RNA Dis. 2016;3(4). pii: e1393. doi: 10.14800/rd.1393. Epub 2016 Aug 15.

28.

Interrogating Endogenous Protein Phosphatase Activity with Rationally Designed Chemosensors.

Beck JR, Lawrence A, Tung AS, Harris EN, Stains CI.

ACS Chem Biol. 2016 Jan 15;11(1):284-90. doi: 10.1021/acschembio.5b00506. Epub 2015 Dec 3.

PMID:
26580981
29.

Disparities in hypertension among black Caribbean populations: a scoping review by the U.S. Caribbean Alliance for Health Disparities Research Group (USCAHDR).

Bidulescu A, Francis DK, Ferguson TS, Bennett NR, Hennis AJ, Wilks R, Harris EN, MacLeish M, Sullivan LW; U.S. Caribbean Alliance for Health Disparities Research Group (USCAHDR).

Int J Equity Health. 2015 Nov 5;14:125. doi: 10.1186/s12939-015-0229-0. Review.

30.

Disparities in cardiovascular disease among Caribbean populations: a systematic literature review.

Francis DK, Bennett NR, Ferguson TS, Hennis AJ, Wilks RJ, Harris EN, MacLeish MM, Sullivan LW; US Caribbean Alliance for Health Disparities Research Group.

BMC Public Health. 2015 Aug 28;15:828. doi: 10.1186/s12889-015-2166-7. Review.

31.

Trends in Longevity in the Americas: Disparities in Life Expectancy in Women and Men, 1965-2010.

Hambleton IR, Howitt C, Jeyaseelan S, Murphy MM, Hennis AJ, Wilks R, Harris EN, MacLeish M, Sullivan L; U.S. Caribbean Alliance for Health Disparities Research Group (USCAHDR).

PLoS One. 2015 Jun 19;10(6):e0129778. doi: 10.1371/journal.pone.0129778. eCollection 2015.

32.

Cause-of-death disparities in the African diaspora: exploring differences among shared-heritage populations.

Hambleton IR, Jeyaseelan S, Howitt C, Sobers-Grannum N, Hennis AJ, Wilks RJ, Harris EN, MacLeish M, Sullivan LW; US Caribbean Alliance for Health Disparities Research Group.

Am J Public Health. 2015 Jul;105 Suppl 3:S491-8. doi: 10.2105/AJPH.2015.302676. Epub 2015 Apr 23.

33.

Disparities in diabetes mellitus among Caribbean populations: a scoping review.

Bennett NR, Francis DK, Ferguson TS, Hennis AJ, Wilks RJ, Harris EN, MacLeish MM, Sullivan LW; U.S. Caribbean Alliance for Health Disparities Research Group (USCAHDR).

Int J Equity Health. 2015 Feb 25;14:23. doi: 10.1186/s12939-015-0149-z. Review.

34.

HARE-Mediated Endocytosis of Hyaluronan and Heparin Is Targeted by Different Subsets of Three Endocytic Motifs.

Pandey MS, Harris EN, Weigel PH.

Int J Cell Biol. 2015;2015:524707. doi: 10.1155/2015/524707. Epub 2015 Mar 25.

35.

In vivo selection to identify bacterial strains with enhanced ecological performance in synbiotic applications.

Krumbeck JA, Maldonado-Gomez MX, Martínez I, Frese SA, Burkey TE, Rasineni K, Ramer-Tait AE, Harris EN, Hutkins RW, Walter J.

Appl Environ Microbiol. 2015 Apr;81(7):2455-65. doi: 10.1128/AEM.03903-14. Epub 2015 Jan 23.

36.

Tissue-specific splice variants of HARE/Stabilin-2 are expressed in bone marrow, lymph node, and spleen.

Hare AK, Harris EN.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):257-61. doi: 10.1016/j.bbrc.2014.11.068. Epub 2014 Nov 24.

37.

Silvia Pierangeli, PhD (1955-2013).

Harris EN, Willis R.

Semin Thromb Hemost. 2014 Mar;40(2):137-9. doi: 10.1055/s-0034-1368795. Epub 2014 Feb 27. No abstract available.

PMID:
24577999
38.

Homogeneous low-molecular-weight heparins with reversible anticoagulant activity.

Xu Y, Cai C, Chandarajoti K, Hsieh PH, Li L, Pham TQ, Sparkenbaugh EM, Sheng J, Key NS, Pawlinski R, Harris EN, Linhardt RJ, Liu J.

Nat Chem Biol. 2014 Apr;10(4):248-50. doi: 10.1038/nchembio.1459. Epub 2014 Feb 23.

39.

Standardization of antiphospholipid antibody testing--historical perspectives and ongoing initiatives.

Willis R, Lakos G, Harris EN.

Semin Thromb Hemost. 2014 Mar;40(2):172-7. doi: 10.1055/s-0033-1364207. Epub 2014 Jan 27. Review.

PMID:
24470286
40.

The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans.

Pandey MS, Baggenstoss BA, Washburn J, Harris EN, Weigel PH.

J Biol Chem. 2013 May 17;288(20):14068-79. doi: 10.1074/jbc.M112.442889. Epub 2013 Mar 24.

41.

Current international initiatives in antiphospholipid antibody testing.

Willis R, Harris EN, Pierangeli SS.

Semin Thromb Hemost. 2012 Jun;38(4):360-74. doi: 10.1055/s-0032-1313564. Epub 2012 May 10. Review.

PMID:
22576664
42.

Probing structural selectivity of synthetic heparin binding to Stabilin protein receptors.

Pempe EH, Xu Y, Gopalakrishnan S, Liu J, Harris EN.

J Biol Chem. 2012 Jun 15;287(25):20774-83. doi: 10.1074/jbc.M111.320069. Epub 2012 Apr 30.

43.

Pathogenesis of the antiphospholipid syndrome.

Willis R, Harris EN, Pierangeli SS.

Semin Thromb Hemost. 2012 Jun;38(4):305-21. doi: 10.1055/s-0032-1311827. Epub 2012 Apr 17. Review.

PMID:
22510982
44.

Estrogenic regulation of S6K1 expression creates a positive regulatory loop in control of breast cancer cell proliferation.

Maruani DM, Spiegel TN, Harris EN, Shachter AS, Unger HA, Herrero-González S, Holz MK.

Oncogene. 2012 Dec 6;31(49):5073-80. doi: 10.1038/onc.2011.657. Epub 2012 Jan 30.

45.

In vivo liver endocytosis followed by purification of liver cells by liver perfusion.

Gopalakrishnan S, Harris EN.

J Vis Exp. 2011 Nov 10;(57). pii: 3138. doi: 10.3791/3138.

46.

Standards and reference materials for the anticardiolipin and anti-β2glycoprotein I assays: a report of recommendations from the APL Task Force at the 13th International Congress on Antiphospholipid Antibodies.

Pierangeli SS, Favaloro EJ, Lakos G, Meroni PL, Tincani A, Wong RC, Harris EN.

Clin Chim Acta. 2012 Jan 18;413(1-2):358-60. doi: 10.1016/j.cca.2011.09.048. Epub 2011 Oct 15.

PMID:
22019907
47.

International consensus guidelines on anticardiolipin and anti-β2-glycoprotein I testing: report from the 13th International Congress on Antiphospholipid Antibodies.

Lakos G, Favaloro EJ, Harris EN, Meroni PL, Tincani A, Wong RC, Pierangeli SS.

Arthritis Rheum. 2012 Jan;64(1):1-10. doi: 10.1002/art.33349. No abstract available.

48.

'Criteria' aPL tests: report of a task force and preconference workshop at the 13th International Congress on Antiphospholipid Antibodies, Galveston, Texas, April 2010.

Pierangeli SS, de Groot PG, Dlott J, Favaloro E, Harris EN, Lakos G, Ortel T, Meroni PL, Otomo K, Pengo V, Tincani A, Wong R, Roubey R.

Lupus. 2011 Feb;20(2):182-90. doi: 10.1177/0961203310395055.

PMID:
21303835
49.

N-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronan.

Harris EN, Parry S, Sutton-Smith M, Pandey MS, Panico M, Morris HR, Haslam SM, Dell A, Weigel PH.

Glycobiology. 2010 Aug;20(8):991-1001. doi: 10.1093/glycob/cwq057. Epub 2010 Apr 14.

50.

Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins.

Harris EN, Baggenstoss BA, Weigel PH.

Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1191-9. doi: 10.1152/ajpgi.90717.2008. Epub 2009 Apr 9.

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