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Items: 1 to 50 of 114

1.

A DNA methylation reader complex that enhances gene transcription.

Harris CJ, Scheibe M, Wongpalee SP, Liu W, Cornett EM, Vaughan RM, Li X, Chen W, Xue Y, Zhong Z, Yen L, Barshop WD, Rayatpisheh S, Gallego-Bartolome J, Groth M, Wang Z, Wohlschlegel JA, Du J, Rothbart SB, Butter F, Jacobsen SE.

Science. 2018 Dec 7;362(6419):1182-1186. doi: 10.1126/science.aar7854.

PMID:
30523112
2.

ADCP1: a novel plant H3K9me2 reader.

Harris CJ, Jacobsen SE.

Cell Res. 2019 Jan;29(1):6-7. doi: 10.1038/s41422-018-0119-2. No abstract available.

PMID:
30514899
3.

Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation.

Li X, Harris CJ, Zhong Z, Chen W, Liu R, Jia B, Wang Z, Li S, Jacobsen SE, Du J.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8793-E8802. doi: 10.1073/pnas.1809841115. Epub 2018 Aug 27.

4.

Time-Averaged Self-Monitored Blood Glucose Values Estimate Hemoglobin A1c Outcomes in Patients With Type 1 Diabetes.

Zhang S, Fan L, Zhang Q, Chang AM, Bastyr EJ 3rd, Harris CJ.

J Diabetes Sci Technol. 2018 Jul;12(4):905-906. doi: 10.1177/1932296818761963. Epub 2018 Mar 7. No abstract available.

5.

Large-scale comparative epigenomics reveals hierarchical regulation of non-CG methylation in Arabidopsis.

Zhang Y, Harris CJ, Liu Q, Liu W, Ausin I, Long Y, Xiao L, Feng L, Chen X, Xie Y, Chen X, Zhan L, Feng S, Li JJ, Wang H, Zhai J, Jacobsen SE.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E1069-E1074. doi: 10.1073/pnas.1716300115. Epub 2018 Jan 16.

6.

Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies.

Wilson CR, Gessner RK, Moosa A, Seldon R, Warner DF, Mizrahi V, Soares de Melo C, Simelane SB, Nchinda A, Abay E, Taylor D, Njoroge M, Brunschwig C, Lawrence N, Boshoff HIM, Barry CE 3rd, Sirgel FA, van Helden P, Harris CJ, Gordon R, Ghidelli-Disse S, Pflaumer H, Boesche M, Drewes G, Sanz O, Santos G, Rebollo-Lopez MJ, Urones B, Selenski C, Lafuente-Monasterio MJ, Axtman M, Lelièvre J, Ballell L, Mueller R, Street LJ, Ghorpade SR, Chibale K.

J Med Chem. 2017 Dec 28;60(24):10118-10134. doi: 10.1021/acs.jmedchem.7b01347. Epub 2017 Dec 7.

7.

Open chemistry: RESTful web APIs, JSON, NWChem and the modern web application.

Hanwell MD, de Jong WA, Harris CJ.

J Cheminform. 2017 Oct 30;9(1):55. doi: 10.1186/s13321-017-0241-z.

8.

Improved Denaturation of Small RNA Duplexes and Its Application for Northern Blotting.

Harris CJ, Baulcombe DC, Molnar A.

Methods Mol Biol. 2017;1580:1-6. doi: 10.1007/978-1-4939-6866-4_1.

PMID:
28439822
9.

Centella asiatica attenuates Aβ-induced neurodegenerative spine loss and dendritic simplification.

Gray NE, Zweig JA, Murchison C, Caruso M, Matthews DG, Kawamoto C, Harris CJ, Quinn JF, Soumyanath A.

Neurosci Lett. 2017 Apr 12;646:24-29. doi: 10.1016/j.neulet.2017.02.072. Epub 2017 Mar 6.

10.

A Successful Treatment of Endoscopic Third Ventriculostomy with Choroid Plexus Cauterization for Hydrocephalus in Walker-Warburg Syndrome.

Tanaka T, Harris CJ, Barnett SS, Litofsky NS.

Case Rep Neurol Med. 2016;2016:7627289. doi: 10.1155/2016/7627289. Epub 2016 Dec 27.

11.

Comparative Performance of Complex-Valued B-Spline and Polynomial Models Applied to Iterative Frequency-Domain Decision Feedback Equalization of Hammerstein Channels.

Chen S, Hong X, Khalaf EF, Alsaadi FE, Harris CJ.

IEEE Trans Neural Netw Learn Syst. 2017 Dec;28(12):2872-2884. doi: 10.1109/TNNLS.2016.2609001. Epub 2016 Sep 23.

PMID:
28113992
12.

Nonlinear Process Fault Diagnosis Based on Serial Principal Component Analysis.

Deng X, Tian X, Chen S, Harris CJ.

IEEE Trans Neural Netw Learn Syst. 2018 Mar;29(3):560-572. doi: 10.1109/TNNLS.2016.2635111. Epub 2016 Dec 22.

PMID:
28026785
13.

Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes.

Harris CJ, Husmann D, Liu W, Kasmi FE, Wang H, Papikian A, Pastor WA, Moissiard G, Vashisht AA, Dangl JL, Wohlschlegel JA, Jacobsen SE.

PLoS Genet. 2016 May 12;12(5):e1005998. doi: 10.1371/journal.pgen.1005998. eCollection 2016 May.

14.

Neurourologic dysfunction: evaluation, surveillance and therapy.

Harris CJ, Lemack GE.

Curr Opin Urol. 2016 Jul;26(4):290-4. doi: 10.1097/MOU.0000000000000290. Review.

PMID:
27088864
15.

Centella asiatica modulates antioxidant and mitochondrial pathways and improves cognitive function in mice.

Gray NE, Harris CJ, Quinn JF, Soumyanath A.

J Ethnopharmacol. 2016 Mar 2;180:78-86. doi: 10.1016/j.jep.2016.01.013. Epub 2016 Jan 16.

16.
17.

Aminopyrazolo[1,5-a]pyrimidines as potential inhibitors of Mycobacterium tuberculosis: Structure activity relationships and ADME characterization.

Soares de Melo C, Feng TS, van der Westhuyzen R, Gessner RK, Street LJ, Morgans GL, Warner DF, Moosa A, Naran K, Lawrence N, Boshoff HI, Barry CE 3rd, Harris CJ, Gordon R, Chibale K.

Bioorg Med Chem. 2015 Nov 15;23(22):7240-50. doi: 10.1016/j.bmc.2015.10.021. Epub 2015 Oct 22. Erratum in: Bioorg Med Chem. 2016 Jan 15;24(2):314. Candice, Soares de Melo [corrected to Soares de Melo, Candice].

PMID:
26522089
18.

FDF-PAGE: a powerful technique revealing previously undetected small RNAs sequestered by complementary transcripts.

Harris CJ, Molnar A, Müller SY, Baulcombe DC.

Nucleic Acids Res. 2015 Sep 3;43(15):7590-9. doi: 10.1093/nar/gkv604. Epub 2015 Jun 13.

19.

Nonlinear Identification Using Orthogonal Forward Regression With Nested Optimal Regularization.

Hong X, Chen S, Gao J, Harris CJ.

IEEE Trans Cybern. 2015 Dec;45(12):2925-36. doi: 10.1109/TCYB.2015.2389524. Epub 2015 Jan 27.

PMID:
25643422
20.

Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.

Durinck S, Stawiski EW, Pavía-Jiménez A, Modrusan Z, Kapur P, Jaiswal BS, Zhang N, Toffessi-Tcheuyap V, Nguyen TT, Pahuja KB, Chen YJ, Saleem S, Chaudhuri S, Heldens S, Jackson M, Peña-Llopis S, Guillory J, Toy K, Ha C, Harris CJ, Holloman E, Hill HM, Stinson J, Rivers CS, Janakiraman V, Wang W, Kinch LN, Grishin NV, Haverty PM, Chow B, Gehring JS, Reeder J, Pau G, Wu TD, Margulis V, Lotan Y, Sagalowsky A, Pedrosa I, de Sauvage FJ, Brugarolas J, Seshagiri S.

Nat Genet. 2015 Jan;47(1):13-21. doi: 10.1038/ng.3146. Epub 2014 Nov 17.

21.

Analysis of patient and technical factors associated with midurethral sling mesh exposure and perforation.

Osborn DJ, Dmochowski RR, Harris CJ, Danford JJ, Kaufman MR, Mock S, Kit LC, McCormick B, Reynolds WS.

Int J Urol. 2014 Nov;21(11):1167-70. doi: 10.1111/iju.12544. Epub 2014 Jul 14.

22.

Oral zinc reduces amyloid burden in Tg2576 mice.

Harris CJ, Voss K, Murchison C, Ralle M, Frahler K, Carter R, Rhoads A, Lind B, Robinson E, Quinn JF.

J Alzheimers Dis. 2014;41(1):179-92. doi: 10.3233/JAD-131703.

23.

Stepwise artificial evolution of a plant disease resistance gene.

Harris CJ, Slootweg EJ, Goverse A, Baulcombe DC.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21189-94. doi: 10.1073/pnas.1311134110. Epub 2013 Dec 9.

24.

Activity of striatal neurons reflects social action and own reward.

Báez-Mendoza R, Harris CJ, Schultz W.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16634-9. doi: 10.1073/pnas.1211342110. Epub 2013 Sep 23.

25.

Strategies for small molecule library design.

Sheppard DW, Lipkin MJ, Harris CJ, Catana C, Stouten PF.

Curr Pharm Des. 2014;20(20):3314-22. Review.

PMID:
23947648
26.

MEF2C Haploinsufficiency features consistent hyperkinesis, variable epilepsy, and has a role in dorsal and ventral neuronal developmental pathways.

Paciorkowski AR, Traylor RN, Rosenfeld JA, Hoover JM, Harris CJ, Winter S, Lacassie Y, Bialer M, Lamb AN, Schultz RA, Berry-Kravis E, Porter BE, Falk M, Venkat A, Vanzo RJ, Cohen JS, Fatemi A, Dobyns WB, Shaffer LG, Ballif BC, Marsh ED.

Neurogenetics. 2013 May;14(2):99-111. doi: 10.1007/s10048-013-0356-y. Epub 2013 Feb 7.

27.

Assessing relapses and response to relapse treatment in patients with multiple sclerosis: a nursing perspective.

Ross AP, Halper J, Harris CJ.

Int J MS Care. 2012 Fall;14(3):148-59. doi: 10.7224/1537-2073-14.3.148.

28.

Elastic-Net Prefiltering for Two-Class Classification.

Hong X, Chen S, Harris CJ.

IEEE Trans Cybern. 2013 Feb;43(1):286-95. doi: 10.1109/TSMCB.2012.2205677. Epub 2012 Jul 18.

PMID:
22829416
29.

Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) as an antiinflammatory target: discovery and in vivo activity of selective pyrazolo[1,5-a]pyrimidine inhibitors using a focused library and structure-based optimization approach.

Kosugi T, Mitchell DR, Fujino A, Imai M, Kambe M, Kobayashi S, Makino H, Matsueda Y, Oue Y, Komatsu K, Imaizumi K, Sakai Y, Sugiura S, Takenouchi O, Unoki G, Yamakoshi Y, Cunliffe V, Frearson J, Gordon R, Harris CJ, Kalloo-Hosein H, Le J, Patel G, Simpson DJ, Sherborne B, Thomas PS, Suzuki N, Takimoto-Kamimura M, Kataoka K.

J Med Chem. 2012 Aug 9;55(15):6700-15. doi: 10.1021/jm300411k. Epub 2012 Jul 31. Erratum in: J Med Chem. 2012 Nov 26;55(22):10312-3.

PMID:
22746295
30.

The design and application of target-focused compound libraries.

Harris CJ, Hill RD, Sheppard DW, Slater MJ, Stouten PF.

Comb Chem High Throughput Screen. 2011 Jul;14(6):521-31.

31.

Case series: 2q33.1 microdeletion syndrome--further delineation of the phenotype.

Balasubramanian M, Smith K, Basel-Vanagaite L, Feingold MF, Brock P, Gowans GC, Vasudevan PC, Cresswell L, Taylor EJ, Harris CJ, Friedman N, Moran R, Feret H, Zackai EH, Theisen A, Rosenfeld JA, Parker MJ.

J Med Genet. 2011 May;48(5):290-8. doi: 10.1136/jmg.2010.084491. Epub 2011 Feb 22.

PMID:
21343628
32.

CCR6: a biomarker for Alzheimer's-like disease in a triple transgenic mouse model.

Subramanian S, Ayala P, Wadsworth TL, Harris CJ, Vandenbark AA, Quinn JF, Offner H.

J Alzheimers Dis. 2010;22(2):619-29. doi: 10.3233/JAD-2010-100852.

33.

A copper-lowering strategy attenuates amyloid pathology in a transgenic mouse model of Alzheimer's disease.

Quinn JF, Harris CJ, Cobb KE, Domes C, Ralle M, Brewer G, Wadsworth TL.

J Alzheimers Dis. 2010;21(3):903-14. doi: 10.3233/JAD-2010-100408.

34.

Probability density estimation with tunable kernels using orthogonal forward regression.

Chen S, Hong X, Harris CJ.

IEEE Trans Syst Man Cybern B Cybern. 2010 Aug;40(4):1101-14. doi: 10.1109/TSMCB.2009.2034732. Epub 2009 Dec 15.

PMID:
20007052
35.
36.

aCGH detects partial tetrasomy of 12p in blood from Pallister-Killian syndrome cases without invasive skin biopsy.

Theisen A, Rosenfeld JA, Farrell SA, Harris CJ, Wetzel HH, Torchia BA, Bejjani BA, Ballif BC, Shaffer LG.

Am J Med Genet A. 2009 May;149A(5):914-8. doi: 10.1002/ajmg.a.32767.

PMID:
19353629
37.

Construction of tunable radial basis function networks using orthogonal forward selection.

Chen S, Hong X, Luk BL, Harris CJ.

IEEE Trans Syst Man Cybern B Cybern. 2009 Apr;39(2):457-66. doi: 10.1109/TSMCB.2008.2006688. Epub 2008 Dec 16.

PMID:
19095548
38.

A-optimality orthogonal forward regression algorithm using branch and bound.

Hong X, Chen S, Harris CJ.

IEEE Trans Neural Netw. 2008 Nov;19(11):1961-7. doi: 10.1109/TNN.2008.2003251.

PMID:
19000965
39.

Potent and selective PPAR-alpha agonist LY518674 upregulates both ApoA-I production and catabolism in human subjects with the metabolic syndrome.

Millar JS, Duffy D, Gadi R, Bloedon LT, Dunbar RL, Wolfe ML, Movva R, Shah A, Fuki IV, McCoy M, Harris CJ, Wang MD, Howey DC, Rader DJ.

Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):140-6. doi: 10.1161/ATVBAHA.108.171223. Epub 2008 Nov 6.

40.

How large does a compound screening collection need to be?

Lipkin MJ, Stevens AP, Livingstone DJ, Harris CJ.

Comb Chem High Throughput Screen. 2008 Jul;11(6):482-93.

PMID:
18673276
41.

Symmetric RBF classifier for nonlinear detection in multiple-antenna-aided systems.

Chen S, Wolfgang A, Harris CJ, Hanzo L.

IEEE Trans Neural Netw. 2008 May;19(5):737-45. doi: 10.1109/TNN.2007.911745.

PMID:
18467204
42.

A forward-constrained regression algorithm for sparse kernel density estimation.

Hong X, Chen S, Harris CJ.

IEEE Trans Neural Netw. 2008 Jan;19(1):193-8. doi: 10.1109/TNN.2007.908645.

PMID:
18269951
43.

Linearization and state estimation of unknown discrete-time nonlinear dynamic systems using recurrent neurofuzzy networks.

Gan Q, Harris CJ.

IEEE Trans Syst Man Cybern B Cybern. 1999;29(6):802-17. doi: 10.1109/3477.809034.

PMID:
18252359
44.

Fuzzy local linearization and local basis function expansion in nonlinear system modeling.

Gan Q, Harris CJ.

IEEE Trans Syst Man Cybern B Cybern. 1999;29(4):559-65. doi: 10.1109/3477.775275.

PMID:
18252333
45.

The relevance vector machine technique for channel equalization application.

Chen S, Gunn SR, Harris CJ.

IEEE Trans Neural Netw. 2001;12(6):1529-32. doi: 10.1109/72.963792.

PMID:
18249985
46.

Generalized neurofuzzy network modeling algorithms using Bézier-Bernstein polynomial functions and additive decomposition.

Hong X, Harris CJ.

IEEE Trans Neural Netw. 2000;11(4):889-902. doi: 10.1109/72.857770.

PMID:
18249817
47.

Piecewise Lyapunov stability conditions of fuzzy systems.

Feng M, Harris CJ.

IEEE Trans Syst Man Cybern B Cybern. 2001;31(2):259-62. doi: 10.1109/3477.915350.

PMID:
18244789
48.

Nonlinear model structure design and construction using orthogonal least squares and D-optimality design.

Hong X, Harris CJ.

IEEE Trans Neural Netw. 2002;13(5):1245-50. doi: 10.1109/TNN.2002.1031959.

PMID:
18244524
49.

Errata to "The relevance vector machine technique for channel equalization application".

Chen S, Gunn SR, Harris CJ.

IEEE Trans Neural Netw. 2002;13(4):1024. doi: 10.1109/TNN.2002.1021902. No abstract available.

PMID:
18244497
50.

Nonlinear model structure detection using optimum experimental design and orthogonal least squares.

Hong X, Harris CJ.

IEEE Trans Neural Netw. 2001;12(2):435-9. doi: 10.1109/72.914539.

PMID:
18244399

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