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Steric regulation of tandem calponin homology domain actin-binding affinity.

Harris AR, Belardi B, Jreij P, Wei K, Shams H, Bausch A, Fletcher DA.

Mol Biol Cell. 2019 Nov 6:mbcE19060317. doi: 10.1091/mbc.E19-06-0317. [Epub ahead of print]


Facile Development of a Fiber-Based Electrode for Highly Selective and Sensitive Detection of Dopamine.

Farajikhah S, Innis PC, Paull B, Wallace GG, Harris AR.

ACS Sens. 2019 Oct 25;4(10):2599-2604. doi: 10.1021/acssensors.9b01583. Epub 2019 Oct 2.


Modeling Emergent Properties in the Brain Using Tissue Models to Investigate Neurodegenerative Disease.

Harris AR, McGivern P, Ooi L.

Neuroscientist. 2019 Sep 13:1073858419870446. doi: 10.1177/1073858419870446. [Epub ahead of print]


NBA team home advantage: Identifying key factors using an artificial neural network.

Harris AR, Roebber PJ.

PLoS One. 2019 Jul 31;14(7):e0220630. doi: 10.1371/journal.pone.0220630. eCollection 2019.


Using Chronopotentiometry to Better Characterize the Charge Injection Mechanisms of Platinum Electrodes Used in Bionic Devices.

Harris AR, Newbold C, Carter P, Cowan R, Wallace GG.

Front Neurosci. 2019 Apr 24;13:380. doi: 10.3389/fnins.2019.00380. eCollection 2019.


Comparison of analytical techniques to explain variability in stored drinking water quality and microbial hand contamination of female caregivers in Tanzania.

Harris AR, Pickering AJ, Boehm AB, Mrisho M, Davis J.

Environ Sci Process Impacts. 2019 May 22;21(5):893-903. doi: 10.1039/c8em00460a.


Predicting neural recording performance of implantable electrodes.

Harris AR, Allitt BJ, Paolini AG.

Analyst. 2019 Apr 23;144(9):2973-2983. doi: 10.1039/c8an02214c.


Two-way communication between ex vivo tissues on a microfluidic chip: application to tumor-lymph node interaction.

Shim S, Belanger MC, Harris AR, Munson JM, Pompano RR.

Lab Chip. 2019 Mar 13;19(6):1013-1026. doi: 10.1039/c8lc00957k.


Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization.

Davoren JE, Nason D, Coe J, Dlugolenski K, Helal C, Harris AR, LaChapelle E, Liang S, Liu Y, O'Connor R, Orozco CC, Rai BK, Salafia M, Samas B, Xu W, Kozak R, Gray D.

J Med Chem. 2018 Dec 27;61(24):11384-11397. doi: 10.1021/acs.jmedchem.8b01622. Epub 2018 Dec 11.


Docetaxel facilitates lymphatic-tumor crosstalk to promote lymphangiogenesis and cancer progression.

Harris AR, Perez MJ, Munson JM.

BMC Cancer. 2018 Jul 6;18(1):718. doi: 10.1186/s12885-018-4619-8.


Measuring the effective area and charge density of platinum electrodes for bionic devices.

Harris AR, Newbold C, Carter P, Cowan R, Wallace GG.

J Neural Eng. 2018 Aug;15(4):046015. doi: 10.1088/1741-2552/aaba8b. Epub 2018 Mar 29.


PEDOT doped with algal, mammalian and synthetic dopants: polymer properties, protein and cell interactions, and influence of electrical stimulation on neuronal cell differentiation.

Molino PJ, Garcia L, Stewart EM, Lamaze M, Zhang B, Harris AR, Winberg P, Wallace GG.

Biomater Sci. 2018 May 1;6(5):1250-1261. doi: 10.1039/c7bm01156c.


Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation.

McAllister LA, Butler CR, Mente S, O'Neil SV, Fonseca KR, Piro JR, Cianfrogna JA, Foley TL, Gilbert AM, Harris AR, Helal CJ, Johnson DS, Montgomery JI, Nason DM, Noell S, Pandit J, Rogers BN, Samad TA, Shaffer CL, da Silva RG, Uccello DP, Webb D, Brodney MA.

J Med Chem. 2018 Apr 12;61(7):3008-3026. doi: 10.1021/acs.jmedchem.8b00070. Epub 2018 Mar 15.


Assessing multiparametric drug response in tissue engineered tumor microenvironment models.

Harris AR, Yuan JX, Munson JM.

Methods. 2018 Feb 1;134-135:20-31. doi: 10.1016/j.ymeth.2017.12.010. Epub 2017 Dec 16.


Fecal Contamination on Produce from Wholesale and Retail Food Markets in Dhaka, Bangladesh.

Harris AR, Islam MA, Unicomb L, Boehm AB, Luby S, Davis J, Pickering AJ.

Am J Trop Med Hyg. 2018 Jan;98(1):287-294. doi: 10.4269/ajtmh.17-0255.


Design and Synthesis of γ- and δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity.

Davoren JE, Garnsey M, Pettersen B, Brodney MA, Edgerton JR, Fortin JP, Grimwood S, Harris AR, Jenkinson S, Kenakin T, Lazzaro JT, Lee CW, Lotarski SM, Nottebaum L, O'Neil SV, Popiolek M, Ramsey S, Steyn SJ, Thorn CA, Zhang L, Webb D.

J Med Chem. 2017 Aug 10;60(15):6649-6663. doi: 10.1021/acs.jmedchem.7b00597. Epub 2017 Jul 26.


Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects.

Davoren JE, Lee CW, Garnsey M, Brodney MA, Cordes J, Dlugolenski K, Edgerton JR, Harris AR, Helal CJ, Jenkinson S, Kauffman GW, Kenakin TP, Lazzaro JT, Lotarski SM, Mao Y, Nason DM, Northcott C, Nottebaum L, O'Neil SV, Pettersen B, Popiolek M, Reinhart V, Salomon-Ferrer R, Steyn SJ, Webb D, Zhang L, Grimwood S.

J Med Chem. 2016 Jul 14;59(13):6313-28. doi: 10.1021/acs.jmedchem.6b00544. Epub 2016 Jul 1.


ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation.

de Jong PR, Taniguchi K, Harris AR, Bertin S, Takahashi N, Duong J, Campos AD, Powis G, Corr M, Karin M, Raz E.

Nat Commun. 2016 May 17;7:11551. doi: 10.1038/ncomms11551.


Culture conditions tailored to the cell of origin are critical for maintaining native properties and tumorigenicity of glioma cells.

Ledur PF, Liu C, He H, Harris AR, Minussi DC, Zhou HY, Shaffrey ME, Asthagiri A, Lopes MB, Schiff D, Lu YC, Mandell JW, Lenz G, Zong H.

Neuro Oncol. 2016 Oct;18(10):1413-24. doi: 10.1093/neuonc/now062. Epub 2016 Apr 21.


Ruminants Contribute Fecal Contamination to the Urban Household Environment in Dhaka, Bangladesh.

Harris AR, Pickering AJ, Harris M, Doza S, Islam MS, Unicomb L, Luby S, Davis J, Boehm AB.

Environ Sci Technol. 2016 May 3;50(9):4642-9. doi: 10.1021/acs.est.5b06282. Epub 2016 Apr 19.


Arrhythmia recognition and classification using combined linear and nonlinear features of ECG signals.

Elhaj FA, Salim N, Harris AR, Swee TT, Ahmed T.

Comput Methods Programs Biomed. 2016 Apr;127:52-63. doi: 10.1016/j.cmpb.2015.12.024. Epub 2016 Jan 20.


Design and optimization of selective azaindole amide M1 positive allosteric modulators.

Davoren JE, O'Neil SV, Anderson DP, Brodney MA, Chenard L, Dlugolenski K, Edgerton JR, Green M, Garnsey M, Grimwood S, Harris AR, Kauffman GW, LaChapelle E, Lazzaro JT, Lee CW, Lotarski SM, Nason DM, Obach RS, Reinhart V, Salomon-Ferrer R, Steyn SJ, Webb D, Yan J, Zhang L.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):650-655. doi: 10.1016/j.bmcl.2015.11.053. Epub 2015 Nov 17.


Correction to Optical and Electrochemical Methods for Determining the Effective Area and Charge Density of Conducting Polymer Modified Electrodes for Neural Stimulation.

Harris AR, Molino PJ, Kapsa RM, Clark GM, Paolini AG, Wallace GG.

Anal Chem. 2015 Nov 17;87(22):11600. doi: 10.1021/acs.analchem.5b03915. Epub 2015 Oct 27. No abstract available.


Thin-film micro-electrode stimulation of the cochlea in rats exposed to aminoglycoside induced hearing loss.

Allitt BJ, Harris AR, Morgan SJ, Clark GM, Paolini AG.

Hear Res. 2016 Jan;331:13-26. doi: 10.1016/j.heares.2015.10.003. Epub 2015 Oct 22.


Emergence of homeostatic epithelial packing and stress dissipation through divisions oriented along the long cell axis.

Wyatt TP, Harris AR, Lam M, Cheng Q, Bellis J, Dimitracopoulos A, Kabla AJ, Charras GT, Baum B.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5726-31. doi: 10.1073/pnas.1420585112. Epub 2015 Apr 23.


Correlation of the impedance and effective electrode area of doped PEDOT modified electrodes for brain-machine interfaces.

Harris AR, Molino PJ, Kapsa RM, Clark GM, Paolini AG, Wallace GG.

Analyst. 2015 May 7;140(9):3164-74. doi: 10.1039/c4an02362e. Epub 2015 Mar 16.


Optical and electrochemical methods for determining the effective area and charge density of conducting polymer modified electrodes for neural stimulation.

Harris AR, Molino PJ, Kapsa RM, Clark GM, Paolini AG, Wallace GG.

Anal Chem. 2015 Jan 6;87(1):738-46. doi: 10.1021/ac503733s. Epub 2014 Dec 23. Erratum in: Anal Chem. 2015 Nov 17;87(22):11600.


TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP.

de Jong PR, Takahashi N, Peiris M, Bertin S, Lee J, Gareau MG, Paniagua A, Harris AR, Herdman DS, Corr M, Blackshaw LA, Raz E.

Mucosal Immunol. 2015 May;8(3):491-504. doi: 10.1038/mi.2014.82. Epub 2014 Oct 1.


Cell mechanics: principles, practices, and prospects.

Moeendarbary E, Harris AR.

Wiley Interdiscip Rev Syst Biol Med. 2014 Sep-Oct;6(5):371-88. Review.


Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis.

de Jong PR, Takahashi N, Harris AR, Lee J, Bertin S, Jeffries J, Jung M, Duong J, Triano AI, Lee J, Niv Y, Herdman DS, Taniguchi K, Kim CW, Dong H, Eckmann L, Stanford SM, Bottini N, Corr M, Raz E.

J Clin Invest. 2014 Sep;124(9):3793-806. doi: 10.1172/JCI72340. Epub 2014 Aug 1.


STAT3: An Anti-Invasive Factor in Colorectal Cancer?

de Jong PR, Mo JH, Harris AR, Lee J, Raz E.

Cancers (Basel). 2014 Jul 3;6(3):1394-407. doi: 10.3390/cancers6031394.


Primary stability recognition of the newly designed cementless femoral stem using digital signal processing.

Baharuddin MY, Salleh ShH, Hamedi M, Zulkifly AH, Lee MH, Mohd Noor A, Harris AR, Abdul Majid N.

Biomed Res Int. 2014;2014:478248. doi: 10.1155/2014/478248. Epub 2014 Apr 1.


Formation of adherens junctions leads to the emergence of a tissue-level tension in epithelial monolayers.

Harris AR, Daeden A, Charras GT.

J Cell Sci. 2014 Jun 1;127(Pt 11):2507-17. doi: 10.1242/jcs.142349. Epub 2014 Mar 21.


A method for systematic electrochemical and electrophysiological evaluation of neural recording electrodes.

Harris AR, Morgan SJ, Wallace GG, Paolini AG.

J Vis Exp. 2014 Mar 3;(85). doi: 10.3791/51084.


Enteric pathogens in stored drinking water and on caregiver's hands in Tanzanian households with and without reported cases of child diarrhea.

Mattioli MC, Boehm AB, Davis J, Harris AR, Mrisho M, Pickering AJ.

PLoS One. 2014 Jan 2;9(1):e84939. doi: 10.1371/journal.pone.0084939. eCollection 2014.


Generating suspended cell monolayers for mechanobiological studies.

Harris AR, Bellis J, Khalilgharibi N, Wyatt T, Baum B, Kabla AJ, Charras GT.

Nat Protoc. 2013 Dec;8(12):2516-30. doi: 10.1038/nprot.2013.151. Epub 2013 Nov 21.


2013 SYR Accepted Poster Abstracts.

Bayley PJ, Isaac L, Kong JY, Adamson MM, Ashford JW, Mahoney LA, Beltran M, Brown-Elhillali A, Held A, Ajayi A, Belcher H, Bond A, Mason H, Lemaster C, Shaw S, Mullin C, Holick E, Saper R, Braun TD, Riley KE, Park CL, Trehern AE, Davis MB, Mastronardi EL, Butzer B, Khalsa SB, Shorter SM, Reinhardt KM, Cope S, Cheung C, Justice C, Wyman J, Cook-Cottone CP, Daly LA, Haden SC, Hagins M, Danhauer SC, Griffin LP, Avis NE, Sohl SJ, Lawrence J, Jesse MT, Addington EL, Messino MJ, Giguere JK, Lucas SL, Wiliford SK, Shaw E, de Manincor M, Bensoussan A, Smith C, Fahey P, Bourchier S, Desrochers DI, Viswanathan S, Partharasathy BR, Doherty K, Moye J, Walsh C, Pokaski-Azar J, Gosian J, Chapman J, King K, Sohl S, Danhauer S, Dunbar E, Gabriel MG, Huebner M, Hofmann SG, Khalsa SB, Gaskins RB, Jennings E, Thind H, Fava JL, Hartman S, Bock BC, Gramann P, Haaz S, Bingham CO, Bartlett SJ, Hagins M, States R, Selfe T, Innes K, Harris AR, Jennings PA, Abenavoli RM, Katz DA, Hudecek KM, Greenberg MT, Jeter PE, Nkodo AF, Haaz S, Dagnelie G, Keosaian JE, Lemaster CM, Chao M, Saper RB, King KD, Gosian J, Doherty K, Walsh C, Pokaski Azar J, Chapman J, Danhauer SC, Moye J, Kinser P, Bourguignon C, Taylor A, Mahoney LA, Bayley PJ, Collery LM, Menzies-Toman D, Nilsson M, Frykman V, Noggle JJ, Braun T, Khalsa SB, Nosaka M, Okamura H, Fukatu N, Potts A, Weidknecht K, Coulombe S, Davies B, Ryan C, Day D, Reale J, Staples JK, Knoefel J, Herman C, Riley KE, Park CL, Bedesin EY, Stewart VM, Riley KE, Braun TD, Park CL, Pescatello LS, Davis MB, Trehern AE, Mastronardi EL, Rioux J, Rosen RK, Thind H, Gaskins R, Jennings E, Morrow K, Williams D, Bock B, Rousseau D, Jackson E, Schmid AA, Miller KK, Van Puymbroeck M, Debaun EL, Schalk N, Dierks TD, Altenburger P, Damush T, Williams LS, Selman L, Citron T, Howie-Esquivel J, McDermott K, Milic M, Donesky D, Shook A, Ruzic R, Galloway F, Van Puymbroeck M, Miller KK, Schalk N, Schmid AA, Ward LJ, Stebbings S, Sherman K, Cherkin D, Baxter GD, West JI, Duffy N, Liang B.

Int J Yoga Therap. 2013;23(1):32-53. No abstract available.


Mechanisms of post-supply contamination of drinking water in Bagamoyo, Tanzania.

Harris AR, Davis J, Boehm AB.

J Water Health. 2013 Sep;11(3):543-54. doi: 10.2166/wh.2013.023.


Postconcussion syndrome (PCS) in the emergency department: predicting and pre-empting persistent symptoms following a mild traumatic brain injury.

Reuben A, Sampson P, Harris AR, Williams H, Yates P.

Emerg Med J. 2014 Jan;31(1):72-7. doi: 10.1136/emermed-2012-201667. Epub 2013 Mar 6. Review.


The cytoplasm of living cells behaves as a poroelastic material.

Moeendarbary E, Valon L, Fritzsche M, Harris AR, Moulding DA, Thrasher AJ, Stride E, Mahadevan L, Charras GT.

Nat Mater. 2013 Mar;12(3):253-61. doi: 10.1038/nmat3517. Epub 2013 Jan 6.


Conducting polymer coated neural recording electrodes.

Harris AR, Morgan SJ, Chen J, Kapsa RM, Wallace GG, Paolini AG.

J Neural Eng. 2013 Feb;10(1):016004. doi: 10.1088/1741-2560/10/1/016004. Epub 2012 Dec 12.


Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion.

Terry SJ, Elbediwy A, Zihni C, Harris AR, Bailly M, Charras GT, Balda MS, Matter K.

PLoS One. 2012;7(11):e50188. doi: 10.1371/journal.pone.0050188. Epub 2012 Nov 19.


From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptor.

Futatsugi K, Mascitti V, Guimarães CR, Morishita N, Cai C, DeNinno MP, Gao H, Hamilton MD, Hank R, Harris AR, Kung DW, Lavergne SY, Lefker BA, Lopaze MG, McClure KF, Munchhof MJ, Preville C, Robinson RP, Wright SW, Bonin PD, Cornelius P, Chen Y, Kalgutkar AS.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):194-7. doi: 10.1016/j.bmcl.2012.10.119. Epub 2012 Nov 5.


Characterizing the mechanics of cultured cell monolayers.

Harris AR, Peter L, Bellis J, Baum B, Kabla AJ, Charras GT.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16449-54. doi: 10.1073/pnas.1213301109. Epub 2012 Sep 18.


Homicide as a medical outcome: racial disparity in deaths from assault in US Level I and II trauma centers.

Harris AR, Fisher GA, Thomas SH.

J Trauma Acute Care Surg. 2012 Mar;72(3):773-82. doi: 10.1097/TA.0b013e318226eb39.


Experimental validation of atomic force microscopy-based cell elasticity measurements.

Harris AR, Charras GT.

Nanotechnology. 2011 Aug 26;22(34):345102. doi: 10.1088/0957-4484/22/34/345102. Epub 2011 Jul 28.


Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist response.

McClure KF, Darout E, Guimarães CR, DeNinno MP, Mascitti V, Munchhof MJ, Robinson RP, Kohrt J, Harris AR, Moore DE, Li B, Samp L, Lefker BA, Futatsugi K, Kung D, Bonin PD, Cornelius P, Wang R, Salter E, Hornby S, Kalgutkar AS, Chen Y.

J Med Chem. 2011 Mar 24;54(6):1948-52. doi: 10.1021/jm200003p. Epub 2011 Mar 1.


Adapted filter banks for feature extraction in transcranial magnetic stimulation evoked responses.

Harris AR, Schwerdtfeger K, Strauss DJ.

Med Biol Eng Comput. 2011 Feb;49(2):221-31. doi: 10.1007/s11517-010-0726-7. Epub 2011 Jan 11.


The barrier method as a new tool to assist in career selection: covert observational study.

McCain RS, Harris AR, McCallion K, Campbell WJ, Kirk SJ.

BMJ. 2010 Dec 15;341:c6968. doi: 10.1136/bmj.c6968.


Incidence estimate of nonmelanoma skin cancer in the United States, 2006.

Rogers HW, Weinstock MA, Harris AR, Hinckley MR, Feldman SR, Fleischer AB, Coldiron BM.

Arch Dermatol. 2010 Mar;146(3):283-7. doi: 10.1001/archdermatol.2010.19.


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