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Items: 41

1.

Author Correction: CasX enzymes comprise a distinct family of RNA-guided genome editors.

Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brötzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA.

Nature. 2019 Apr;568(7752):E8-E10. doi: 10.1038/s41586-019-1084-8.

PMID:
30944483
2.

CasX enzymes comprise a distinct family of RNA-guided genome editors.

Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brötzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA.

Nature. 2019 Feb;566(7743):218-223. doi: 10.1038/s41586-019-0908-x. Epub 2019 Feb 4. Erratum in: Nature. 2019 Apr;568(7752):E8-E10.

PMID:
30718774
3.

A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System.

Wright AV, Wang JY, Burstein D, Harrington LB, Paez-Espino D, Kyrpides NC, Iavarone AT, Banfield JF, Doudna JA.

Mol Cell. 2019 Feb 21;73(4):727-737.e3. doi: 10.1016/j.molcel.2018.12.015. Epub 2019 Jan 29.

PMID:
30709710
4.

Adiposity throughout the life course and risk of venous thromboembolism.

Hagan KA, Harrington LB, Kim J, Lindström S, Camargo CA Jr, Grodstein F, Kabrhel C.

Thromb Res. 2018 Dec;172:67-73. doi: 10.1016/j.thromres.2018.10.024. Epub 2018 Oct 26.

PMID:
30384037
5.

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.

Harrington LB, Burstein D, Chen JS, Paez-Espino D, Ma E, Witte IP, Cofsky JC, Kyrpides NC, Banfield JF, Doudna JA.

Science. 2018 Nov 16;362(6416):839-842. doi: 10.1126/science.aav4294. Epub 2018 Oct 18.

PMID:
30337455
6.

Alcohol consumption and the risk of incident pulmonary embolism in US women and men.

Harrington LB, Hagan KA, Mukamal KJ, Kang JH, Kim J, Crous-Bou M, Lindström S, Rimm EB, Kabrhel C, Jensen MK.

J Thromb Haemost. 2018 Sep;16(9):1753-1762. doi: 10.1111/jth.14224. Epub 2018 Aug 12.

PMID:
29974610
7.

Reduction in physical function in women after venous thromboembolism.

Hagan KA, Harrington LB, Kim J, Zeleznik O, Rimm EB, Grodstein F, Kabrhel C.

J Thromb Haemost. 2018 Jun 8. doi: 10.1111/jth.14196. [Epub ahead of print]

PMID:
29883039
8.

Interaction of a genetic risk score with physical activity, physical inactivity, and body mass index in relation to venous thromboembolism risk.

Kim J, Kraft P, Hagan KA, Harrington LB, Lindstroem S, Kabrhel C.

Genet Epidemiol. 2018 Jun;42(4):354-365. doi: 10.1002/gepi.22118. Epub 2018 Mar 8.

9.

Vasomotor symptoms and the risk of incident venous thrombosis in postmenopausal women.

Harrington LB, Blondon M, Cushman M, Kaunitz AM, Allison MA, Wang L, Sullivan S, Woods NF, LaCroix AZ, Heckbert SR, McKnight B, Rossouw J, Smith NL.

J Thromb Haemost. 2018 May;16(5):886-892. doi: 10.1111/jth.13993. Epub 2018 Apr 2.

10.

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.

Chen JS, Ma E, Harrington LB, Da Costa M, Tian X, Palefsky JM, Doudna JA.

Science. 2018 Apr 27;360(6387):436-439. doi: 10.1126/science.aar6245. Epub 2018 Feb 15.

PMID:
29449511
11.

Metabolomic analysis of 92 pulmonary embolism patients from a nested case-control study identifies metabolites associated with adverse clinical outcomes.

Zeleznik OA, Poole EM, Lindstrom S, Kraft P, Van Hylckama Vlieg A, Lasky-Su JA, Harrington LB, Hagan K, Kim J, Parry BA, Giordano N, Kabrhel C.

J Thromb Haemost. 2018 Mar;16(3):500-507. doi: 10.1111/jth.13937. Epub 2018 Jan 30.

12.

A thermostable Cas9 with increased lifetime in human plasma.

Harrington LB, Paez-Espino D, Staahl BT, Chen JS, Ma E, Kyrpides NC, Doudna JA.

Nat Commun. 2017 Nov 10;8(1):1424. doi: 10.1038/s41467-017-01408-4.

13.

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.

Chen JS, Dagdas YS, Kleinstiver BP, Welch MM, Sousa AA, Harrington LB, Sternberg SH, Joung JK, Yildiz A, Doudna JA.

Nature. 2017 Oct 19;550(7676):407-410. doi: 10.1038/nature24268. Epub 2017 Sep 20.

14.

A Broad-Spectrum Inhibitor of CRISPR-Cas9.

Harrington LB, Doxzen KW, Ma E, Liu JJ, Knott GJ, Edraki A, Garcia B, Amrani N, Chen JS, Cofsky JC, Kranzusch PJ, Sontheimer EJ, Davidson AR, Maxwell KL, Doudna JA.

Cell. 2017 Sep 7;170(6):1224-1233.e15. doi: 10.1016/j.cell.2017.07.037. Epub 2017 Aug 24.

15.

New CRISPR-Cas systems from uncultivated microbes.

Burstein D, Harrington LB, Strutt SC, Probst AJ, Anantharaman K, Thomas BC, Doudna JA, Banfield JF.

Nature. 2017 Feb 9;542(7640):237-241. doi: 10.1038/nature21059. Epub 2016 Dec 22.

16.

The cross-sectional association between vasomotor symptoms and hemostatic parameter levels in postmenopausal women.

Harrington LB, Blondon M, Cushman M, Kaunitz AM, Rossouw JE, Allison MA, Martin LW, Johnson KC, Rosing J, Woods NF, LaCroix AZ, Heckbert SR, McKnight B, Smith NL.

Menopause. 2017 Apr;24(4):360-370. doi: 10.1097/GME.0000000000000777.

17.

Cross-sectional association of endogenous steroid hormone, sex hormone-binding globulin, and precursor steroid levels with hemostatic factor levels in postmenopausal women.

Harrington LB, Marck BT, Wiggins KL, McKnight B, Heckbert SR, Woods NF, LaCroix AZ, Blondon M, Psaty BM, Rosendaal FR, Matsumoto AM, Smith NL.

J Thromb Haemost. 2017 Jan;15(1):80-90. doi: 10.1111/jth.13554. Epub 2017 Jan 8.

18.

Environmental and Genetic Risk Factors Associated with Venous Thromboembolism.

Crous-Bou M, Harrington LB, Kabrhel C.

Semin Thromb Hemost. 2016 Nov;42(8):808-820. Epub 2016 Oct 20. Review.

19.

Rapid Thermostabilization of Bacillus thuringiensis Serovar Konkukian 97-27 Dehydroshikimate Dehydratase through a Structure-Based Enzyme Design and Whole Cell Activity Assay.

Harrington LB, Jha RK, Kern TL, Schmidt EN, Canales GM, Finney KB, Koppisch AT, Strauss CE, Fox DT.

ACS Synth Biol. 2017 Jan 20;6(1):120-129. doi: 10.1021/acssynbio.6b00159. Epub 2016 Sep 1.

PMID:
27548779
20.

Native Mass Spectrometry Characterizes the Photosynthetic Reaction Center Complex from the Purple Bacterium Rhodobacter sphaeroides.

Zhang H, Harrington LB, Lu Y, Prado M, Saer R, Rempel D, Blankenship RE, Gross ML.

J Am Soc Mass Spectrom. 2017 Jan;28(1):87-95. doi: 10.1007/s13361-016-1451-8. Epub 2016 Aug 9.

21.

Pre-pregnancy BMI, delivery BMI, gestational weight gain and the risk of postpartum venous thrombosis.

Blondon M, Harrington LB, Boehlen F, Robert-Ebadi H, Righini M, Smith NL.

Thromb Res. 2016 Sep;145:151-6. doi: 10.1016/j.thromres.2016.06.026. Epub 2016 Jun 24.

PMID:
27421192
22.

CRISPR Immunological Memory Requires a Host Factor for Specificity.

Nuñez JK, Bai L, Harrington LB, Hinder TL, Doudna JA.

Mol Cell. 2016 Jun 16;62(6):824-833. doi: 10.1016/j.molcel.2016.04.027. Epub 2016 May 19.

23.

The association of statin therapy with the risk of recurrent venous thrombosis.

Smith NL, Harrington LB, Blondon M, Wiggins KL, Floyd JS, Sitlani CM, McKnight B, Larson EB, Rosendaal FR, Heckbert SR, Psaty BM.

J Thromb Haemost. 2016 Jul;14(7):1384-92. doi: 10.1111/jth.13334. Epub 2016 Jun 20.

24.

Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering.

Nuñez JK, Harrington LB, Doudna JA.

ACS Chem Biol. 2016 Mar 18;11(3):681-8. doi: 10.1021/acschembio.5b01019. Epub 2016 Feb 9. Review.

PMID:
26857072
25.

Hysterectomy and Bilateral Salpingo-Oophorectomy: Variations by History of Military Service and Birth Cohort.

Callegari LS, Gray KE, Zephyrin LC, Harrington LB, Gerber MR, Cochrane BB, Weitlauf JC, Bean-Mayberry B, Bastian LA, Mattocks KM, Haskell SG, Katon JG.

Gerontologist. 2016 Feb;56 Suppl 1:S67-77. doi: 10.1093/geront/gnv666.

26.

Prior hysterectomy and oophorectomy and incident venous thrombosis risk among postmenopausal women: a population-based, case-control study.

Harrington LB, Weiss NS, Wiggins KL, Heckbert SR, McKnight B, Blondon M, Woods NF, LaCroix AZ, Psaty BM, Smith NL.

Menopause. 2016 Feb;23(2):143-9. doi: 10.1097/GME.0000000000000591.

27.

The association of F11 genetic variants with the risk of incident venous thrombosis among women, by statin use.

Harrington LB, Wiggins KL, Sitlani CM, Blondon M, van Hylckama Vlieg A, Rosendaal FR, Heckbert SR, Psaty BM, Smith NL.

Thromb Haemost. 2016 Mar;115(3):682-4. doi: 10.1160/TH15-08-0683. Epub 2015 Dec 3. No abstract available.

28.

Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes.

Ma E, Harrington LB, O'Connell MR, Zhou K, Doudna JA.

Mol Cell. 2015 Nov 5;60(3):398-407. doi: 10.1016/j.molcel.2015.10.030.

29.

Foreign DNA capture during CRISPR-Cas adaptive immunity.

Nuñez JK, Harrington LB, Kranzusch PJ, Engelman AN, Doudna JA.

Nature. 2015 Nov 26;527(7579):535-8. doi: 10.1038/nature15760. Epub 2015 Oct 21.

30.

Vasomotor Symptoms and Quality of Life Among Veteran and Non-Veteran Postmenopausal Women.

Katon JG, Gray KE, Gerber MR, Harrington LB, Woods NF, Weitlauf JC, Bean-Mayberry B, Goldstein KM, Hunt JR, Katon WJ, Haskell SG, McCutcheon SJ, Gass ML, Gibson CJ, Zephyrin LC.

Gerontologist. 2016 Feb;56 Suppl 1:S40-53. doi: 10.1093/geront/gnv104. Epub 2015 Jul 28.

PMID:
26220418
31.

Association between newborn birth weight and the risk of postpartum maternal venous thromboembolism: a population-based case-control study.

Blondon M, Quon BS, Harrington LB, Bounameaux H, Smith NL.

Circulation. 2015 Apr 28;131(17):1471-6; discussion 1476. doi: 10.1161/CIRCULATIONAHA.114.012749. Epub 2015 Mar 5.

PMID:
25745022
32.

Racial and ethnic differences in the risk of postpartum venous thromboembolism: a population-based, case-control study.

Blondon M, Harrington LB, Righini M, Boehlen F, Bounameaux H, Smith NL.

J Thromb Haemost. 2014 Dec;12(12):2002-9. doi: 10.1111/jth.12747. Epub 2014 Nov 14.

33.

Evidence of functional trimeric chlorophyll a/c2-peridinin proteins in the dinoflagellate Symbiodinium.

Jiang J, Zhang H, Orf GS, Lu Y, Xu W, Harrington LB, Liu H, Lo CS, Blankenship RE.

Biochim Biophys Acta. 2014 Nov;1837(11):1904-1912. doi: 10.1016/j.bbabio.2014.07.023. Epub 2014 Aug 19.

34.

Age-specific strategies for immunization reminders and recalls: a registry-based randomized trial.

Dombkowski KJ, Costello LE, Harrington LB, Dong S, Kolasa M, Clark SJ.

Am J Prev Med. 2014 Jul;47(1):1-8. doi: 10.1016/j.amepre.2014.02.009. Epub 2014 Apr 18.

PMID:
24750973
35.

Differential associations of oral estradiol and conjugated equine estrogen with hemostatic biomarkers.

Blondon M, van Hylckama Vlieg A, Wiggins KL, Harrington LB, McKnight B, Rice KM, Rosendaal FR, Heckbert SR, Psaty BM, Smith NL.

J Thromb Haemost. 2014 Jun;12(6):879-86. doi: 10.1111/jth.12560.

36.

Lower risk of cardiovascular events in postmenopausal women taking oral estradiol compared with oral conjugated equine estrogens.

Smith NL, Blondon M, Wiggins KL, Harrington LB, van Hylckama Vlieg A, Floyd JS, Hwang M, Bis JC, McKnight B, Rice KM, Lumley T, Rosendaal FR, Heckbert SR, Psaty BM.

JAMA Intern Med. 2014 Jan;174(1):25-31. doi: 10.1001/jamainternmed.2013.11074. Erratum in: JAMA Intern Med. 2014 Sep;174(9):1523.

37.

Lack of strong effect modification by NFE2L2/CYP3A5/ABO of the risk of venous thrombosis associated with oral hormone therapy.

Blondon M, Wiggins KL, Harrington LB, Psaty BM, Smith NL.

J Thromb Haemost. 2013 Aug;11(8):1617-9. doi: 10.1111/jth.12309. No abstract available.

38.

Characterization and deposition of various light-harvesting antenna complexes by electrospray atomization.

Shah VB, Orf GS, Reisch S, Harrington LB, Prado M, Blankenship RE, Biswas P.

Anal Bioanal Chem. 2012 Nov;404(8):2329-38. doi: 10.1007/s00216-012-6368-x. Epub 2012 Sep 15.

PMID:
22983169
39.

Feasibility of initiating and sustaining registry-based immunization recall in private practices.

Dombkowski KJ, Cowan AE, Harrington LB, Allred NJ, Hudson E, Clark SJ.

Acad Pediatr. 2012 Mar-Apr;12(2):104-9. doi: 10.1016/j.acap.2012.01.002. Epub 2012 Feb 8.

PMID:
22321815
40.

Seasonal influenza vaccination reminders for children with high-risk conditions: a registry-based randomized trial.

Dombkowski KJ, Harrington LB, Dong S, Clark SJ.

Am J Prev Med. 2012 Jan;42(1):71-5. doi: 10.1016/j.amepre.2011.09.028.

PMID:
22176850
41.

Lysophosphatidic acid-regulated mitogenic ERK signaling in androgen-insensitive prostate cancer PC-3 cells.

Kue PF, Taub JS, Harrington LB, Polakiewicz RD, Ullrich A, Daaka Y.

Int J Cancer. 2002 Dec 20;102(6):572-9.

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