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Items: 21

1.

Histone H2AX promotes neuronal health by controlling mitochondrial homeostasis.

Weyemi U, Paul BD, Bhattacharya D, Malla AP, Boufraqech M, Harraz MM, Bonner WM, Snyder SH.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7471-7476. doi: 10.1073/pnas.1820245116. Epub 2019 Mar 25.

PMID:
30910969
2.

Antidepressant Actions of Ketamine Mediated by the Mechanistic Target of Rapamycin, Nitric Oxide, and Rheb.

Harraz MM, Snyder SH.

Neurotherapeutics. 2017 Jul;14(3):728-733. doi: 10.1007/s13311-017-0540-0. Review.

3.

Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase.

Fu C, Xu J, Cheng W, Rojas T, Chin AC, Snowman AM, Harraz MM, Snyder SH.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2036-2041. doi: 10.1073/pnas.1700165114. Epub 2017 Feb 2.

4.

A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1.

Wang Y, An R, Umanah GK, Park H, Nambiar K, Eacker SM, Kim B, Bao L, Harraz MM, Chang C, Chen R, Wang JE, Kam TI, Jeong JS, Xie Z, Neifert S, Qian J, Andrabi SA, Blackshaw S, Zhu H, Song H, Ming GL, Dawson VL, Dawson TM.

Science. 2016 Oct 7;354(6308). pii: aad6872.

5.

Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade.

Guha P, Harraz MM, Snyder SH.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1417-22. doi: 10.1073/pnas.1524860113. Epub 2016 Jan 19. Erratum in: Proc Natl Acad Sci U S A. 2017 Mar 7;114(10 ):E2066-E2067.

6.

Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation.

Harraz MM, Tyagi R, Cortés P, Snyder SH.

Mol Psychiatry. 2016 Mar;21(3):313-9. doi: 10.1038/mp.2015.211. Epub 2016 Jan 19.

7.

Human GAPDH Is a Target of Aspirin's Primary Metabolite Salicylic Acid and Its Derivatives.

Choi HW, Tian M, Manohar M, Harraz MM, Park SW, Schroeder FC, Snyder SH, Klessig DF.

PLoS One. 2015 Nov 25;10(11):e0143447. doi: 10.1371/journal.pone.0143447. eCollection 2015.

8.

Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase.

Ahmed I, Sbodio JI, Harraz MM, Tyagi R, Grima JC, Albacarys LK, Hubbi ME, Xu R, Kim S, Paul BD, Snyder SH.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9751-6. doi: 10.1073/pnas.1511810112. Epub 2015 Jul 20.

9.

Nitric Oxide-GAPDH Transcriptional Signaling Mediates Behavioral Actions of Cocaine.

Harraz MM, Snyder SH.

CNS Neurol Disord Drug Targets. 2015;14(6):757-63. Review.

10.

MiR-223 regulates the differentiation of immature neurons.

Harraz MM, Xu JC, Guiberson N, Dawson TM, Dawson VL.

Mol Cell Ther. 2014 Jun 17;2(18). pii: 18.

11.

Botch is a γ-glutamyl cyclotransferase that deglycinates and antagonizes Notch.

Chi Z, Byrne ST, Dolinko A, Harraz MM, Kim MS, Umanah G, Zhong J, Chen R, Zhang J, Xu J, Chen L, Pandey A, Dawson TM, Dawson VL.

Cell Rep. 2014 May 8;7(3):681-8. doi: 10.1016/j.celrep.2014.03.048. Epub 2014 Apr 24.

12.

Inositol polyphosphate multikinase is a transcriptional coactivator required for immediate early gene induction.

Xu R, Paul BD, Smith DR, Tyagi R, Rao F, Khan AB, Blech DJ, Vandiver MS, Harraz MM, Guha P, Ahmed I, Sen N, Gallagher M, Snyder SH.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16181-6. doi: 10.1073/pnas.1315551110. Epub 2013 Sep 16.

13.

MicroRNA-223 is neuroprotective by targeting glutamate receptors.

Harraz MM, Eacker SM, Wang X, Dawson TM, Dawson VL.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18962-7. doi: 10.1073/pnas.1121288109. Epub 2012 Oct 29.

14.

Botch promotes neurogenesis by antagonizing Notch.

Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL.

Dev Cell. 2012 Apr 17;22(4):707-20. doi: 10.1016/j.devcel.2012.02.011. Epub 2012 Mar 22.

15.

MicroRNAs in Parkinson's disease.

Harraz MM, Dawson TM, Dawson VL.

J Chem Neuroanat. 2011 Oct;42(2):127-30. doi: 10.1016/j.jchemneu.2011.01.005. Epub 2011 Feb 2. Review.

16.

SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model.

Harraz MM, Marden JJ, Zhou W, Zhang Y, Williams A, Sharov VS, Nelson K, Luo M, Paulson H, Schöneich C, Engelhardt JF.

J Clin Invest. 2008 Feb;118(2):659-70. doi: 10.1172/JCI34060.

17.

Advances in neuronal cell death 2007.

Harraz MM, Dawson TM, Dawson VL.

Stroke. 2008 Feb;39(2):286-8. doi: 10.1161/STROKEAHA.107.511857. Epub 2008 Jan 10. Review. No abstract available.

PMID:
18187674
18.

MKK6 phosphorylation regulates production of superoxide by enhancing Rac GTPase activity.

Harraz MM, Park A, Abbott D, Zhou W, Zhang Y, Engelhardt JF.

Antioxid Redox Signal. 2007 Nov;9(11):1803-13.

19.

Redox modifier genes in amyotrophic lateral sclerosis in mice.

Marden JJ, Harraz MM, Williams AJ, Nelson K, Luo M, Paulson H, Engelhardt JF.

J Clin Invest. 2007 Oct;117(10):2913-9.

20.

Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes.

Li Q, Harraz MM, Zhou W, Zhang LN, Ding W, Zhang Y, Eggleston T, Yeaman C, Banfi B, Engelhardt JF.

Mol Cell Biol. 2006 Jan;26(1):140-54.

21.

Radioprotective effect of melatonin assessed by measuring chromosomal damage in mitotic and meiotic cells.

Badr FM, El Habit OH, Harraz MM.

Mutat Res. 1999 Aug 18;444(2):367-72.

PMID:
10521676

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