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Items: 1 to 50 of 110

1.

Blocking fatty acid-fueled mROS production within macrophages alleviates acute gouty inflammation.

Hall CJ, Sanderson LE, Lawrence LM, Pool B, van der Kroef M, Ashimbayeva E, Britto D, Harper JL, Lieschke GJ, Astin JW, Crosier KE, Dalbeth N, Crosier PS.

J Clin Invest. 2018 May 1;128(5):1752-1771. doi: 10.1172/JCI94584. Epub 2018 Mar 26.

2.

The Mincle ligand trehalose dibehenate differentially modulates M1-like and M2-like macrophage phenotype and function via Syk signaling.

Kodar K, Harper JL, McConnell MJ, Timmer MSM, Stocker BL.

Immun Inflamm Dis. 2017 Dec;5(4):503-514. doi: 10.1002/iid3.186. Epub 2017 Jul 19.

3.

Blackcurrant anthocyanins modulate CCL11 secretion and suppress allergic airway inflammation.

Shaw OM, Nyanhanda T, McGhie TK, Harper JL, Hurst RD.

Mol Nutr Food Res. 2017 Sep;61(9). doi: 10.1002/mnfr.201600868. Epub 2017 Apr 27.

PMID:
28393456
4.

The analgesic and anti-inflammatory effects of Salvinorin A analogue β-tetrahydropyran Salvinorin B in mice.

Paton KF, Kumar N, Crowley RS, Harper JL, Prisinzano TE, Kivell BM.

Eur J Pain. 2017 Jul;21(6):1039-1050. doi: 10.1002/ejp.1002. Epub 2017 Feb 3.

5.

The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques.

McGary CS, Alvarez X, Harrington S, Cervasi B, Ryan ES, Iriele RI, Paganini S, Harper JL, Easley K, Silvestri G, Ansari AA, Lichterfeld M, Micci L, Paiardini M.

Mucosal Immunol. 2017 Jul;10(4):1082-1096. doi: 10.1038/mi.2016.116. Epub 2017 Jan 4.

6.

Delayed liver regeneration in C3H/HeJ mice: possible involvement of haemodynamic and structural changes in the hepatic microcirculation.

Marlini M, Mabuchi A, Mallard BL, Hairulhisyam N, Akashi-Takamura S, Harper JL, Wheatley AM.

Exp Physiol. 2016 Dec 1;101(12):1492-1505. doi: 10.1113/EP085727.

PMID:
27634415
7.

Boysenberry ingestion supports fibrolytic macrophages with the capacity to ameliorate chronic lung remodeling.

Shaw OM, Hurst RD, Harper JL.

Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L628-38. doi: 10.1152/ajplung.00309.2015. Epub 2016 Jul 1.

8.

Absence of airway inflammation in a large proportion of adolescents with asthma.

Brooks CR, van Dalen CJ, Zacharasiewicz A, Simpson JL, Harper JL, Le Gros G, Gibson PG, Pearce N, Douwes J.

Respirology. 2016 Apr;21(3):460-6. doi: 10.1111/resp.12701. Epub 2015 Dec 22.

9.

Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques.

Micci L, Ryan ES, Fromentin R, Bosinger SE, Harper JL, He T, Paganini S, Easley KA, Chahroudi A, Benne C, Gumber S, McGary CS, Rogers KA, Deleage C, Lucero C, Byrareddy SN, Apetrei C, Estes JD, Lifson JD, Piatak M Jr, Chomont N, Villinger F, Silvestri G, Brenchley JM, Paiardini M.

J Clin Invest. 2015 Dec;125(12):4497-513. doi: 10.1172/JCI81400. Epub 2015 Nov 9.

10.

Monosodium Urate Crystals Induce Upregulation of NK1.1-Dependent Killing by Macrophages and Support Tumor-Resident NK1.1+ Monocyte/Macrophage Populations in Antitumor Therapy.

Steiger S, Kuhn S, Ronchese F, Harper JL.

J Immunol. 2015 Dec 1;195(11):5495-502. doi: 10.4049/jimmunol.1401755. Epub 2015 Nov 2.

11.

A Phenomic Scan of the Norfolk Island Genetic Isolate Identifies a Major Pleiotropic Effect Locus Associated with Metabolic and Renal Disorder Markers.

Benton MC, Lea RA, Macartney-Coxson D, Hanna M, Eccles DA, Carless MA, Chambers GK, Bellis C, Goring HH, Curran JE, Harper JL, Gibson G, Blangero J, Griffiths LR.

PLoS Genet. 2015 Oct 16;11(10):e1005593. doi: 10.1371/journal.pgen.1005593. eCollection 2015 Oct.

12.

IL-1βR-dependent priming of antitumor CD4+ T cells and sustained antitumor immunity after peri-tumoral treatment with MSU and mycobacteria.

Kuhn S, Yang J, Hyde EJ, Harper JL, Kirman JR, Ronchese F.

Oncoimmunology. 2015 Jun 26;4(10):e1042199. eCollection 2015 Oct.

13.

Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B.

Harper JL, Khalil IM, Shaw L, Bourguet-Kondracki ML, Dubois J, Valentin A, Barker D, Copp BR.

Mar Drugs. 2015 Aug 10;13(8):5102-10. doi: 10.3390/md13085102.

14.

Incorporating Patient Satisfaction Metrics in Assessing Multidisciplinary Breast Cancer Care Quality.

Harper JL, De Costa AM, Garrett-Mayer E, Sterba KR.

South Med J. 2015 Jun;108(6):372-6. doi: 10.14423/SMJ.0000000000000300.

15.

Placental changes caused by food restriction during early pregnancy in mice are reversible.

Harper JL, Caesar GA, Pennington KA, Davis JW, Schulz LC.

Reproduction. 2015 Sep;150(3):165-72.

16.

A Role for Gut Microbiota and the Metabolite-Sensing Receptor GPR43 in a Murine Model of Gout.

Vieira AT, Macia L, Galvão I, Martins FS, Canesso MC, Amaral FA, Garcia CC, Maslowski KM, De Leon E, Shim D, Nicoli JR, Harper JL, Teixeira MM, Mackay CR.

Arthritis Rheumatol. 2015 Jun;67(6):1646-56. doi: 10.1002/art.39107.

17.

Role of miR-146a in regulation of the acute inflammatory response to monosodium urate crystals.

Dalbeth N, Pool B, Shaw OM, Harper JL, Tan P, Franklin C, House ME, Cornish J, Naot D.

Ann Rheum Dis. 2015 Apr;74(4):786-90. doi: 10.1136/annrheumdis-2014-205409. Epub 2015 Feb 2.

PMID:
25646371
18.

The uptake of trehalose glycolipids by macrophages is independent of Mincle.

Kodar K, Eising S, Khan AA, Steiger S, Harper JL, Timmer MS, Stocker BL.

Chembiochem. 2015 Mar 2;16(4):683-93. doi: 10.1002/cbic.201402506. Epub 2015 Feb 2.

PMID:
25645884
19.

Discovery of lipids from B. longum subsp. infantis using whole cell MALDI analysis.

Timmer MS, Sauvageau J, Foster AJ, Ryan J, Lagutin K, Shaw O, Harper JL, Sims IM, Stocker BL.

J Org Chem. 2014 Aug 15;79(16):7332-41. doi: 10.1021/jo501016c. Epub 2014 Aug 1.

PMID:
25032516
21.

The effect of diet-induced obesity on the inflammatory phenotype of non-adipose-resident macrophages in an in vivo model of gout.

Shaw OM, Pool B, Dalbeth N, Harper JL.

Rheumatology (Oxford). 2014 Oct;53(10):1901-5. doi: 10.1093/rheumatology/keu174. Epub 2014 May 15.

PMID:
24831058
22.

Blackcurrant cultivar polyphenolic extracts suppress CCL26 secretion from alveolar epithelial cells.

Nyanhanda T, Gould EM, McGhie T, Shaw OM, Harper JL, Hurst RD.

Food Funct. 2014 Apr;5(4):671-7. doi: 10.1039/c3fo60568j.

PMID:
24526266
23.

Mechanisms of spontaneous resolution of acute gouty inflammation.

Steiger S, Harper JL.

Curr Rheumatol Rep. 2014 Jan;16(1):392. doi: 10.1007/s11926-013-0392-5. Review.

PMID:
24343224
24.

Cytosine arabinoside and mitoxantrone followed by second allogeneic transplant for the treatment of children with refractory juvenile myelomonocytic leukemia.

Patel SA, Coulter DW, Grovas AC, Gordon BG, Harper JL, Warkentin PI, Wisecarver JL, Sanger WG, Coccia PF.

J Pediatr Hematol Oncol. 2014 Aug;36(6):491-4. doi: 10.1097/MPH.0000000000000077.

25.

Mapping eQTLs in the Norfolk Island genetic isolate identifies candidate genes for CVD risk traits.

Benton MC, Lea RA, Macartney-Coxson D, Carless MA, Göring HH, Bellis C, Hanna M, Eccles D, Chambers GK, Curran JE, Harper JL, Blangero J, Griffiths LR.

Am J Hum Genet. 2013 Dec 5;93(6):1087-99. doi: 10.1016/j.ajhg.2013.11.004.

26.

Increased numbers of monocyte-derived dendritic cells during successful tumor immunotherapy with immune-activating agents.

Kuhn S, Hyde EJ, Yang J, Rich FJ, Harper JL, Kirman JR, Ronchese F.

J Immunol. 2013 Aug 15;191(4):1984-92. doi: 10.4049/jimmunol.1301135. Epub 2013 Jul 15.

27.

Multifocal histologically malignant Epstein-Barr virus-associated smooth muscle tumor in a pediatric transplant patient with an indolent course.

Kazmi SA, Aizenberg MR, Harper JL, McComb RD.

Int J Surg Pathol. 2014 Apr;22(2):186-9. doi: 10.1177/1066896913494793. Epub 2013 Jul 9.

PMID:
23842005
28.

An efficient single prime protocol for the induction of antigen-induced airways inflammation.

Shaw OM, Harper JL.

J Immunol Methods. 2013 Sep 30;395(1-2):79-82. doi: 10.1016/j.jim.2013.06.007. Epub 2013 Jul 4.

PMID:
23831610
29.

A one-dimensional mixed porohyperelastic transport swelling finite element model with growth.

Harper JL, Simon BR, Vande Geest JP.

J Mech Behav Biomed Mater. 2014 Jan;29:663-75. doi: 10.1016/j.jmbbm.2013.04.019. Epub 2013 May 7.

30.

A modified superantigen rescues Ly6G- CD11b+ blood monocyte suppressor function and suppresses antigen-specific inflammation in EAE.

Slaney CY, Toker A, Fraser JD, Harper JL, Bäckström BT.

Autoimmunity. 2013 Jun;46(4):269-78. doi: 10.3109/08916934.2013.767893.

PMID:
23374140
32.

Hyperuricaemia elevates circulating CCL2 levels and primes monocyte trafficking in subjects with inter-critical gout.

Grainger R, McLaughlin RJ, Harrison AA, Harper JL.

Rheumatology (Oxford). 2013 Jun;52(6):1018-21. doi: 10.1093/rheumatology/kes326. Epub 2012 Nov 30.

PMID:
23204548
33.

Application of a novel strategy of engineering conditional alleles to a single exon gene, Sox2.

Mandalos N, Saridaki M, Harper JL, Kotsoni A, Yang P, Economides AN, Remboutsika E.

PLoS One. 2012;7(9):e45768. doi: 10.1371/journal.pone.0045768. Epub 2012 Sep 27.

34.

Effect of food restriction and leptin supplementation on fetal programming in mice.

Pennington KA, Harper JL, Sigafoos AN, Beffa LM, Carleton SM, Phillips CL, Schulz LC.

Endocrinology. 2012 Sep;153(9):4556-67. doi: 10.1210/en.2012-1119. Epub 2012 Jul 9.

35.

Induction of T cell responses and recruitment of an inflammatory dendritic cell subset following tumor immunotherapy with Mycobacterium smegmatis.

Rich FJ, Kuhn S, Hyde EJ, Harper JL, Ronchese F, Kirman JR.

Cancer Immunol Immunother. 2012 Dec;61(12):2333-42. doi: 10.1007/s00262-012-1291-8. Epub 2012 Jun 20.

PMID:
22714285
36.

Pharmacological concentrations of ascorbate radiosensitize glioblastoma multiforme primary cells by increasing oxidative DNA damage and inhibiting G2/M arrest.

Herst PM, Broadley KW, Harper JL, McConnell MJ.

Free Radic Biol Med. 2012 Apr 15;52(8):1486-93. doi: 10.1016/j.freeradbiomed.2012.01.021. Epub 2012 Feb 2.

PMID:
22342518
37.
38.

Bradykinin receptor 2 extends inflammatory cell recruitment in a model of acute gouty arthritis.

Shaw OM, Harper JL.

Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):266-9. doi: 10.1016/j.bbrc.2011.10.137. Epub 2011 Nov 6.

PMID:
22079285
39.

Long-chain lipids are required for the innate immune recognition of trehalose diesters by macrophages.

Khan AA, Chee SH, McLaughlin RJ, Harper JL, Kamena F, Timmer MS, Stocker BL.

Chembiochem. 2011 Nov 25;12(17):2572-6. doi: 10.1002/cbic.201100451. Epub 2011 Oct 11.

PMID:
21990105
40.

Indigenous New Zealand honeys exhibit multiple anti-inflammatory activities.

Leong AG, Herst PM, Harper JL.

Innate Immun. 2012 Jun;18(3):459-66. doi: 10.1177/1753425911422263. Epub 2011 Oct 6.

PMID:
21978989
41.

Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum.

Chan ST, Pearce AN, Januario AH, Page MJ, Kaiser M, McLaughlin RJ, Harper JL, Webb VL, Barker D, Copp BR.

J Org Chem. 2011 Nov 4;76(21):9151-6. doi: 10.1021/jo201654h. Epub 2011 Oct 3.

PMID:
21958335
42.

Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues.

Ainge GD, Martin WJ, Compton BJ, Hayman CM, Larsen DS, Yoon SI, Wilson IA, Harper JL, Painter GF.

J Med Chem. 2011 Oct 27;54(20):7268-79. doi: 10.1021/jm2008419. Epub 2011 Oct 5.

43.

Glatiramer acetate treatment directly targets CD11b(+)Ly6G(-) monocytes and enhances the suppression of autoreactive T cells in experimental autoimmune encephalomyelitis.

Toker A, Slaney CY, Bäckström BT, Harper JL.

Scand J Immunol. 2011 Sep;74(3):235-243. doi: 10.1111/j.1365-3083.2011.02575.x.

44.

Chemical synthesis and immunosuppressive activity of dipalmitoyl phosphatidylinositol hexamannoside.

Ainge GD, Compton BJ, Hayman CM, Martin WJ, Toms SM, Larsen DS, Harper JL, Painter GF.

J Org Chem. 2011 Jun 17;76(12):4941-51. doi: 10.1021/jo200588u. Epub 2011 May 24.

PMID:
21574597
45.
46.

Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp.

Finlayson R, Pearce AN, Page MJ, Kaiser M, Bourguet-Kondracki ML, Harper JL, Webb VL, Copp BR.

J Nat Prod. 2011 Apr 25;74(4):888-92. doi: 10.1021/np1008619. Epub 2011 Feb 24.

PMID:
21348447
47.

A PIM₂ analogue suppresses allergic airway disease.

Harper JL, Hayman CM, Larsen DS, Painter GF, Singh-Gill G.

Bioorg Med Chem. 2011 Jan 15;19(2):917-25. doi: 10.1016/j.bmc.2010.11.058. Epub 2010 Dec 2.

PMID:
21215641
48.

Toxicity, response rates and survival outcomes of induction cisplatin and irinotecan followed by concurrent cisplatin, irinotecan and radiotherapy for locally advanced esophageal cancer.

Watkins JM, Zauls AJ, Kearney PL, Shirai K, Ruppert BN, Harper JL, Sherman CA, Aguero EG, Reed CE, Sharma AK.

Jpn J Clin Oncol. 2011 Mar;41(3):334-42. doi: 10.1093/jjco/hyq208. Epub 2010 Nov 17.

PMID:
21084436
49.

Naïve blood monocytes suppress T-cell function. A possible mechanism for protection from autoimmunity.

Slaney CY, Toker A, La Flamme A, Bäckström BT, Harper JL.

Immunol Cell Biol. 2011 Jan;89(1):7-13. doi: 10.1038/icb.2010.110. Epub 2010 Nov 9.

PMID:
21060323
50.

Outcomes in women treated with MammoSite brachytherapy or whole breast irradiation stratified by ASTRO Accelerated Partial Breast Irradiation Consensus Statement Groups.

Zauls AJ, Watkins JM, Wahlquist AE, Brackett NC 3rd, Aguero EG, Baker MK, Jenrette JM, Garrett-Mayer E, Harper JL.

Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):21-9. doi: 10.1016/j.ijrobp.2010.08.034. Epub 2010 Oct 15.

PMID:
20951508

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