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Items: 1 to 50 of 2142

1.

A Tat/Rev Induced Limiting Dilution Assay to Measure Viral Reservoirs in Non-Human Primate Models of HIV Infection.

Frank I, Acharya A, Routhu NK, Aravantinou M, Harper JL, Maldonado S, Sole Cigoli M, Semova S, Mazel S, Paiardini M, Derby N, Byrareddy SN, Martinelli E.

Sci Rep. 2019 Aug 19;9(1):12078. doi: 10.1038/s41598-019-48354-3.

2.

Genetic databases and donor anonymity.

Kennett D, Reisel D, Harper J.

Hum Reprod. 2019 Aug 16. pii: dez143. doi: 10.1093/humrep/dez143. [Epub ahead of print] No abstract available.

PMID:
31418780
3.

The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells.

Jacoupy M, Hamon-Keromen E, Ordureau A, Erpapazoglou Z, Coge F, Corvol JC, Nosjean O, Mannoury la Cour C, Millan MJ, Boutin JA, Harper JW, Brice A, Guedin D, Gautier CA, Corti O.

Sci Rep. 2019 Aug 14;9(1):11829. doi: 10.1038/s41598-019-47352-9.

4.

National trends in CT utilization and estimated CT-related radiation exposure in the evaluation and follow-up of stone patients.

Dai JC, Chang HC, Holt SK, Harper JD.

Urology. 2019 Aug 9. pii: S0090-4295(19)30705-8. doi: 10.1016/j.urology.2019.07.030. [Epub ahead of print]

PMID:
31404583
5.

A Reactive Antibody Platform for One-Step Production of Antibody-Drug Conjugates through a Diels-Alder Reaction with Maleimide.

St Amant AH, Huang F, Lin J, Lemen D, Chakiath C, Mao S, Fazenbaker C, Zhong H, Harper J, Xu W, Patel N, Adams L, Vijayakrishnan B, Howard PW, Marelli M, Wu H, Gao C, Read de Alaniz J, Christie RJ.

Bioconjug Chem. 2019 Aug 19. doi: 10.1021/acs.bioconjchem.9b00436. [Epub ahead of print]

PMID:
31380623
6.

Acute unfolding of a single protein immediately stimulates recruitment of ubiquitin protein ligase E3C (UBE3C) to 26S proteasomes.

Gottlieb CD, Thompson ACS, Ordureau A, Harper JW, Kopito RR.

J Biol Chem. 2019 Aug 2. pii: jbc.RA119.009654. doi: 10.1074/jbc.RA119.009654. [Epub ahead of print]

7.

Differential gene expression and gene ontologies associated with increasing water-stress in leaf and root transcriptomes of perennial ryegrass (Lolium perenne).

Fradera-Sola A, Thomas A, Gasior D, Harper J, Hegarty M, Armstead I, Fernandez-Fuentes N.

PLoS One. 2019 Jul 30;14(7):e0220518. doi: 10.1371/journal.pone.0220518. eCollection 2019.

8.

Diagnosis and management of children with Blue Rubber Bleb Nevus Syndrome: A multi-center case series.

Isoldi S, Belsha D, Yeop I, Uc A, Zevit N, Mamula P, Loizides AM, Tabbers M, Cameron D, Day AS, Abu-El-Haija M, Chongsrisawat V, Briars G, Lindley KJ, Koeglmeier J, Shah N, Harper J, Syed SB, Thomson M.

Dig Liver Dis. 2019 Jul 26. pii: S1590-8658(19)30679-6. doi: 10.1016/j.dld.2019.04.020. [Epub ahead of print]

PMID:
31358484
9.

Reply to: Inhaled Corticosteroids and Adult Asthma.

Beasley R, Harper J, Bird G, Maijers I, Weatherall M, Pavord ID.

Am J Respir Crit Care Med. 2019 Jul 24. doi: 10.1164/rccm.201907-1408LE. [Epub ahead of print] No abstract available.

PMID:
31339340
10.

Quantitative assessment of effectiveness of ultrasonic propulsion of kidney stones.

Dai JC, Sorensen MD, Chang HC, Samson PC, Dunmire B, Cunitz BW, Thiel J, Liu Z, Bailey MR, Harper JD.

J Endourol. 2019 Jul 23. doi: 10.1089/end.2019.0340. [Epub ahead of print]

PMID:
31333058
11.

Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C.

Kendrick AA, Dickey AM, Redwine WB, Tran PT, Vaites LP, Dzieciatkowska M, Harper JW, Reck-Peterson SL.

J Cell Biol. 2019 Jul 18. pii: jcb.201812170. doi: 10.1083/jcb.201812170. [Epub ahead of print]

PMID:
31320392
12.

Sliding dominates slow-flowing margin regions, Greenland Ice Sheet.

Maier N, Humphrey N, Harper J, Meierbachtol T.

Sci Adv. 2019 Jul 10;5(7):eaaw5406. doi: 10.1126/sciadv.aaw5406. eCollection 2019 Jul.

13.

Optimizing oncolytic virotherapy in cancer treatment.

Harrington K, Freeman DJ, Kelly B, Harper J, Soria JC.

Nat Rev Drug Discov. 2019 Jul 10. doi: 10.1038/s41573-019-0029-0. [Epub ahead of print] Review.

PMID:
31292532
14.

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial.

Di WL, Lwin SM, Petrova A, Bernadis C, Syed F, Farzaneh F, Moulding D, Martinez AE, Sebire NJ, Rampling D, Virasami A, Zamiri M, Wang W, Hara H, Kadiyirire T, Abdul-Wahab A, Martinez-Queipo M, Harper JI, McGrath JA, Thrasher AJ, Mellerio JE, Qasim W.

Hum Gene Ther. 2019 Aug 5. doi: 10.1089/hum.2019.049. [Epub ahead of print]

PMID:
31288584
15.

Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers.

Gregson SJ, Barrett AM, Patel NV, Kang GD, Schiavone D, Sult E, Barry CS, Vijayakrishnan B, Adams LR, Masterson LA, D'Hooge F, Snaith M, Harper J, Hartley JA, Howard PW.

Eur J Med Chem. 2019 Jun 18;179:591-607. doi: 10.1016/j.ejmech.2019.06.044. [Epub ahead of print]

PMID:
31279293
16.

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation.

Timms RT, Zhang Z, Rhee DY, Harper JW, Koren I, Elledge SJ.

Science. 2019 Jul 5;365(6448). pii: eaaw4912. doi: 10.1126/science.aaw4912.

PMID:
31273098
17.

Solid State Multicolor Emission in Substitutional Solid Solutions of Metal-Organic Frameworks.

Newsome WJ, Ayad S, Cordova J, Reinheimer EW, Campiglia AD, Harper JK, Hanson K, Uribe-Romo FJ.

J Am Chem Soc. 2019 Jul 17;141(28):11298-11303. doi: 10.1021/jacs.9b05191. Epub 2019 Jul 2.

PMID:
31265284
18.

Requirements for improving health and well-being of children with Prader-Willi syndrome and their families.

Mackay J, McCallum Z, Ambler GR, Vora K, Nixon G, Bergman P, Shields N, Milner K, Kapur N, Crock P, Caudri D, Curran J, Verge C, Seton C, Tai A, Tham E, Musthaffa Y, Lafferty AR, Blecher G, Harper J, Schofield C, Nielsen A, Wilson A, Leonard H, Choong CS, Downs J.

J Paediatr Child Health. 2019 Jun 30. doi: 10.1111/jpc.14546. [Epub ahead of print] Review.

PMID:
31257692
19.

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, Schulman BA, Gross JD, Krogan NJ.

Cell Host Microbe. 2019 Jul 10;26(1):86-99.e7. doi: 10.1016/j.chom.2019.05.008. Epub 2019 Jun 25.

PMID:
31253590
20.

Protocol for a randomised, single-blind, two-arm, parallel-group controlled trial of the efficacy of rhinothermy delivered by nasal high flow therapy in the treatment of the common cold.

Bird G, Braithwaite I, Harper J, McKinstry S, Koorevaar I, Fingleton J, Semprini A, Dilcher M, Jennings L, Weatherall M, Beasley R.

BMJ Open. 2019 Jun 19;9(6):e028098. doi: 10.1136/bmjopen-2018-028098.

21.

Use of anti-CRISPR protein AcrIIA4 as a capture ligand for CRISPR/Cas9 detection.

Johnston RK, Seamon KJ, Saada EA, Podlevsky JD, Branda SS, Timlin JA, Harper JC.

Biosens Bioelectron. 2019 May 31;141:111361. doi: 10.1016/j.bios.2019.111361. [Epub ahead of print]

PMID:
31207570
22.

Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells.

Brennan CM, Vaites LP, Wells JN, Santaguida S, Paulo JA, Storchova Z, Harper JW, Marsh JA, Amon A.

Genes Dev. 2019 Aug 1;33(15-16):1031-1047. doi: 10.1101/gad.327494.119. Epub 2019 Jun 13.

PMID:
31196865
23.

Ribosome Abundance Control Via the Ubiquitin-Proteasome System and Autophagy.

An H, Harper JW.

J Mol Biol. 2019 Jun 11. pii: S0022-2836(19)30353-5. doi: 10.1016/j.jmb.2019.06.001. [Epub ahead of print] Review.

PMID:
31195016
24.

Are we ready for genome editing in human embryos for clinical purposes?

Harper JC, Schatten G.

Eur J Med Genet. 2019 Aug;62(8):103682. doi: 10.1016/j.ejmg.2019.103682. Epub 2019 May 29. Review.

PMID:
31150829
25.

Detecting bliss synergy in in vivo combination studies with a tumor kinetic model.

Zhao W, Vicini P, Novick S, Anderton J, Davies G, DAngelo G, O'Day T, Yu B, Harper J, Narwal R, Roskos L, Yang H.

Pharm Stat. 2019 May 29. doi: 10.1002/pst.1952. [Epub ahead of print]

PMID:
31140720
26.

Treatment Utilization and Medical Problems in a Community Sample of Adult Women With Anorexia Nervosa.

Brodrick B, Harper JA, Van Enkevort E, McAdams CJ.

Front Psychol. 2019 May 3;10:981. doi: 10.3389/fpsyg.2019.00981. eCollection 2019.

28.

Computed Tomography Radiation Exposure Among Referred Kidney Stone Patients: Results from the Registry for Stones of the Kidney and Ureter.

Tzou DT, Zetumer S, Usawachintachit M, Taguchi K, Bechis SK, Duty BD, Harper JD, Hsi RS, Sorensen M, Sur RL, Reliford-Titus S, Chang HC, Isaacson D, Bayne DB, Wang ZJ, Stoller ML, Chi T.

J Endourol. 2019 Jul;33(7):619-624. doi: 10.1089/end.2019.0091. Epub 2019 May 29.

29.

A Diene-Containing Noncanonical Amino Acid Enables Dual Functionality in Proteins: Rapid Diels-Alder Reaction with Maleimide or Proximity-Based Dimerization.

St Amant AH, Huang F, Lin J, Rickert K, Oganesyan V, Lemen D, Mao S, Harper J, Marelli M, Wu H, Gao C, Read de Alaniz J, Christie RJ.

Angew Chem Int Ed Engl. 2019 Jun 17;58(25):8489-8493. doi: 10.1002/anie.201903494. Epub 2019 May 14.

PMID:
31018033
30.

Target-related parietal P3 and medial frontal theta index the genetic risk for problematic substance use.

Harper J, Malone SM, Iacono WG.

Psychophysiology. 2019 Aug;56(8):e13383. doi: 10.1111/psyp.13383. Epub 2019 Apr 23.

PMID:
31012496
31.

TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.

An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW.

Mol Cell. 2019 Jun 6;74(5):891-908.e10. doi: 10.1016/j.molcel.2019.03.034. Epub 2019 Apr 18.

PMID:
31006537
32.

Innovations in Ultrasound Technology in the Management of Kidney Stones.

Dai JC, Bailey MR, Sorensen MD, Harper JD.

Urol Clin North Am. 2019 May;46(2):273-285. doi: 10.1016/j.ucl.2018.12.009. Epub 2019 Mar 4. Review.

PMID:
30961860
33.

Asthma paradoxes: time for a new approach across the spectrum of asthma severity.

Beasley R, Bird G, Harper J, Weatherall M.

Eur Respir J. 2019 Apr 4;53(4). pii: 1900218. doi: 10.1183/13993003.00218-2019. Print 2019 Apr. No abstract available.

PMID:
30948506
34.

Novel tretinoin 0.05% lotion for the once-daily treatment of moderate-to-severe acne vulgaris: assessment of safety and tolerability in subgroups.

Harper JC, Roberts WE, Zeichner JA, Guenin E, Bhatt V, Pillai R.

J Dermatolog Treat. 2019 Apr 2:1-8. doi: 10.1080/09546634.2019.1587884. [Epub ahead of print]

PMID:
30935257
35.

Potentiation of PBD Dimers by Lipophilicity Manipulation.

Cailleau T, Adams LR, Arora N, Kang GD, Masterson L, Patel N, Hartley JA, Mao S, Harper J, Howard PW.

Curr Top Med Chem. 2019;19(9):741-752. doi: 10.2174/1568026619666190401112517.

PMID:
30931859
36.

Improved Inhibition of Tumor Growth by Diabody-Drug Conjugates via Half-Life Extension.

Li Q, Barrett A, Vijayakrishnan B, Tiberghien A, Beard R, Rickert KW, Allen KL, Christie RJ, Marelli M, Harper J, Howard P, Wu H, Dall'Acqua WF, Tsui P, Gao C, Borrok MJ.

Bioconjug Chem. 2019 Apr 17;30(4):1232-1243. doi: 10.1021/acs.bioconjchem.9b00170. Epub 2019 Apr 3.

PMID:
30912649
37.

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids.

Piccolis M, Bond LM, Kampmann M, Pulimeno P, Chitraju C, Jayson CBK, Vaites LP, Boland S, Lai ZW, Gabriel KR, Elliott SD, Paulo JA, Harper JW, Weissman JS, Walther TC, Farese RV Jr.

Mol Cell. 2019 Apr 4;74(1):32-44.e8. doi: 10.1016/j.molcel.2019.01.036. Epub 2019 Mar 4.

PMID:
30846318
38.

A Fruitful Journey: Pollen Tube Navigation from Germination to Fertilization.

Johnson MA, Harper JF, Palanivelu R.

Annu Rev Plant Biol. 2019 Apr 29;70:809-837. doi: 10.1146/annurev-arplant-050718-100133. Epub 2019 Mar 1.

PMID:
30822112
39.

Feasibility and acceptability of theatrical and visual art to deliver fertility education to young adults.

Harper JC, Hepburn J, Vautier G, Callander E, Glasgow T, Balen A, Boivin J.

Hum Fertil (Camb). 2019 Mar 1:1-7. doi: 10.1080/14647273.2019.1570354. [Epub ahead of print]

PMID:
30821537
40.

MSU Crystals Enhance TDB-Mediated Inflammatory Macrophage IL-1β Secretion.

Wahi K, Kodar K, McConnell MJ, Harper JL, Timmer MSM, Stocker BL.

Inflammation. 2019 Jun;42(3):1129-1136. doi: 10.1007/s10753-019-00976-5.

PMID:
30806957
41.

Interactions of an Anti-Sickling Drug with Hemoglobin in Red Blood Cells from a Patient with Sickle Cell Anemia.

Strader MB, Liang H, Meng F, Harper J, Ostrowski DA, Henry ER, Shet AS, Eaton WA, Thein SL, Alayash AI.

Bioconjug Chem. 2019 Mar 20;30(3):568-571. doi: 10.1021/acs.bioconjchem.9b00130. Epub 2019 Feb 28.

PMID:
30794381
42.

Root imaging showing comparisons in root distribution and ontogeny in novel Festulolium populations and closely related perennial ryegrass varieties.

Humphreys MW, Doonan JH, Boyle R, Rodriguez AC, Marley CL, Williams K, Farrell MS, Brook J, Gasior D, Loka D, Collins RP, Marshall AH, Allen DK, Yadav RS, Dungait JAJ, Murray P, Harper JA.

Food Energy Secur. 2018 Nov;7(4):e00145. doi: 10.1002/fes3.145. Epub 2018 Oct 2.

43.

Direct analysis of pollen fitness by flow cytometry: implications for pollen response to stress.

Luria G, Rutley N, Lazar I, Harper JF, Miller G.

Plant J. 2019 Jun;98(5):942-952. doi: 10.1111/tpj.14286. Epub 2019 Mar 18.

PMID:
30758085
44.

Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence.

Neurohr GE, Terry RL, Lengefeld J, Bonney M, Brittingham GP, Moretto F, Miettinen TP, Vaites LP, Soares LM, Paulo JA, Harper JW, Buratowski S, Manalis S, van Werven FJ, Holt LJ, Amon A.

Cell. 2019 Feb 21;176(5):1083-1097.e18. doi: 10.1016/j.cell.2019.01.018. Epub 2019 Feb 7.

45.

Integrating a newly developed BAC-based physical mapping resource for Lolium perenne with a genome-wide association study across a L. perenne European ecotype collection identifies genomic contexts associated with agriculturally important traits.

Harper J, De Vega J, Swain S, Heavens D, Gasior D, Thomas A, Evans C, Lovatt A, Lister S, Thorogood D, Skøt L, Hegarty M, Blackmore T, Kudrna D, Byrne S, Asp T, Powell W, Fernandez-Fuentes N, Armstead I.

Ann Bot. 2019 Jun 24;123(6):977-992. doi: 10.1093/aob/mcy230.

46.

Inhaled Corticosteroid Therapy in Adult Asthma. Time for a New Therapeutic Dose Terminology.

Beasley R, Harper J, Bird G, Maijers I, Weatherall M, Pavord ID.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1471-1477. doi: 10.1164/rccm.201810-1868CI.

PMID:
30645143
47.

NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms.

Santana-Codina N, Gableske S, Rey MQD, Małachowska B, Jedrychowski MP, Biancur DE, Schmidt PJ, Fleming MD, Fendler W, Harper JW, Kimmelman AC, Mancias JD.

Haematologica. 2019 Jul;104(7):1342-1354. doi: 10.3324/haematol.2018.204123. Epub 2019 Jan 10.

48.

Survey and genetic characterization of Vibrio cholerae in Apalachicola Bay, Florida (2012-2014).

Fang L, Ginn AM, Harper J, Kane AS, Wright AC.

J Appl Microbiol. 2019 Apr;126(4):1265-1277. doi: 10.1111/jam.14199. Epub 2019 Jan 31.

PMID:
30629784
49.

RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway.

Heo JM, Ordureau A, Swarup S, Paulo JA, Shen K, Sabatini DM, Harper JW.

Sci Adv. 2018 Nov 21;4(11):eaav0443. doi: 10.1126/sciadv.aav0443. eCollection 2018 Nov.

50.

The effects of trehalose glycolipid presentation on cytokine production by GM-CSF macrophages.

Stocker BL, Kodar K, Wahi K, Foster AJ, Harper JL, Mori D, Yamasaki S, Timmer MSM.

Glycoconj J. 2019 Feb;36(1):69-78. doi: 10.1007/s10719-018-09857-9. Epub 2019 Jan 8.

PMID:
30617946

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