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Items: 1 to 50 of 321

1.

Artificial intelligence in neuropathology: deep learning-based assessment of tauopathy.

Signaevsky M, Prastawa M, Farrell K, Tabish N, Baldwin E, Han N, Iida MA, Koll J, Bryce C, Purohit D, Haroutunian V, McKee AC, Stein TD, White CL 3rd, Walker J, Richardson TE, Hanson R, Donovan MJ, Cordon-Cardo C, Zeineh J, Fernandez G, Crary JF.

Lab Invest. 2019 Jul;99(7):1019-1029. doi: 10.1038/s41374-019-0202-4. Epub 2019 Feb 15.

PMID:
30770886
2.

The expression of long noncoding RNA NEAT1 is reduced in schizophrenia and modulates oligodendrocytes transcription.

Katsel P, Roussos P, Fam P, Khan S, Tan W, Hirose T, Nakagawa S, Pletnikov MV, Haroutunian V.

NPJ Schizophr. 2019 Jan 29;5(1):3. doi: 10.1038/s41537-019-0071-2.

3.

Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia.

Fullard JF, Charney AW, Voloudakis G, Uzilov AV, Haroutunian V, Roussos P.

Transl Psychiatry. 2019 Jan 17;9(1):21. doi: 10.1038/s41398-018-0342-0.

4.

Combination of Insulin with a GLP1 Agonist Is Associated with Better Memory and Normal Expression of Insulin Receptor Pathway Genes in a Mouse Model of Alzheimer's Disease.

Robinson A, Lubitz I, Atrakchi-Baranes D, Licht-Murava A, Katsel P, Leroith D, Liraz-Zaltsman S, Haroutunian V, Beeri MS.

J Mol Neurosci. 2019 Apr;67(4):504-510. doi: 10.1007/s12031-019-1257-9. Epub 2019 Jan 11.

PMID:
30635783
5.

Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer's disease and normalized by treatment with anti-diabetic agents.

Katsel P, Roussos P, Beeri MS, Gama-Sosa MA, Gandy S, Khan S, Haroutunian V.

PLoS One. 2018 Nov 1;13(11):e0206547. doi: 10.1371/journal.pone.0206547. eCollection 2018.

6.

Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments.

Sullivan CR, Mielnik CA, O'Donovan SM, Funk AJ, Bentea E, DePasquale EA, Alganem K, Wen Z, Haroutunian V, Katsel P, Ramsey AJ, Meller J, McCullumsmith RE.

Mol Neurobiol. 2019 Jun;56(6):4492-4517. doi: 10.1007/s12035-018-1390-4. Epub 2018 Oct 18.

PMID:
30338483
7.

CDT2-controlled cell cycle reentry regulates the pathogenesis of Alzheimer's disease.

Huang F, Wang M, Liu R, Wang JZ, Schadt E, Haroutunian V, Katsel P, Zhang B, Wang X.

Alzheimers Dement. 2019 Feb;15(2):217-231. doi: 10.1016/j.jalz.2018.08.013. Epub 2018 Oct 12.

8.

Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.

Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, Bennett DA, De Jager PL.

Nat Genet. 2018 Nov;50(11):1584-1592. doi: 10.1038/s41588-018-0238-1. Epub 2018 Oct 8.

9.

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, Mahajan M, Mangravite LM, Dammer EB, Duong DM, Lah JJ, Seyfried NT, Levey AI, Buxbaum JD, Ehrlich M, Gandy S, Katsel P, Haroutunian V, Schadt E, Zhang B.

Sci Data. 2018 Sep 11;5:180185. doi: 10.1038/sdata.2018.185.

10.

Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia.

Bryois J, Garrett ME, Song L, Safi A, Giusti-Rodriguez P, Johnson GD, Shieh AW, Buil A, Fullard JF, Roussos P, Sklar P, Akbarian S, Haroutunian V, Stockmeier CA, Wray GA, White KP, Liu C, Reddy TE, Ashley-Koch A, Sullivan PF, Crawford GE.

Nat Commun. 2018 Aug 7;9(1):3121. doi: 10.1038/s41467-018-05379-y.

11.

Sex differences in DEK expression in the anterior cingulate cortex and its association with dementia severity in schizophrenia.

O'Donovan SM, Franco-Villanueva A, Ghisays V, Caldwell JL, Haroutunian V, Privette Vinnedge LM, McCullumsmith RE, Solomon MB.

Schizophr Res. 2018 Dec;202:188-194. doi: 10.1016/j.schres.2018.07.010. Epub 2018 Jul 13.

PMID:
30017458
12.

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.

Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P.

Hum Mol Genet. 2018 Jun 29. doi: 10.1093/hmg/ddy229. [Epub ahead of print] No abstract available.

PMID:
29982455
13.

Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.

Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT.

Neuron. 2018 Jul 11;99(1):64-82.e7. doi: 10.1016/j.neuron.2018.05.023. Epub 2018 Jun 21.

14.

Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.

Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, Lunnon K.

Alzheimers Dement. 2018 Dec;14(12):1580-1588. doi: 10.1016/j.jalz.2018.01.017. Epub 2018 Mar 15.

15.

Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer's disease at various cognitive stages.

Poirel O, Mella S, Videau C, Ramet L, Davoli MA, Herzog E, Katsel P, Mechawar N, Haroutunian V, Epelbaum J, Daumas S, El Mestikawy S.

Sci Rep. 2018 Jan 17;8(1):938. doi: 10.1038/s41598-018-19154-y.

16.

Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.

McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, Levey AI, Katsel P, Haroutunian V, Schadt EE, Popko B, Casaccia P, Zhang B.

Mol Neurodegener. 2017 Nov 6;12(1):82. doi: 10.1186/s13024-017-0219-3.

17.

Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development.

Katsel P, Fam P, Tan W, Khan S, Yang C, Jouroukhin Y, Rudchenko S, Pletnikov MV, Haroutunian V.

Schizophr Bull. 2018 Apr 6;44(3):515-524. doi: 10.1093/schbul/sbx106.

18.

Microvascular anomaly conditions in psychiatric disease. Schizophrenia - angiogenesis connection.

Katsel P, Roussos P, Pletnikov M, Haroutunian V.

Neurosci Biobehav Rev. 2017 Jun;77:327-339. doi: 10.1016/j.neubiorev.2017.04.003. Epub 2017 Apr 8. Review.

19.

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.

Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P.

Hum Mol Genet. 2017 May 15;26(10):1942-1951. doi: 10.1093/hmg/ddx103.

20.

Localized cortical chronic traumatic encephalopathy pathology after single, severe axonal injury in human brain.

Shively SB, Edgerton SL, Iacono D, Purohit DP, Qu BX, Haroutunian V, Davis KL, Diaz-Arrastia R, Perl DP.

Acta Neuropathol. 2017 Mar;133(3):353-366. doi: 10.1007/s00401-016-1649-7. Epub 2016 Nov 24.

21.

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, Antaki D, Shetty A, Holmans PA, Pinto D, Gujral M, Brandler WM, Malhotra D, Wang Z, Fajarado KVF, Maile MS, Ripke S, Agartz I, Albus M, Alexander M, Amin F, Atkins J, Bacanu SA, Belliveau RA Jr, Bergen SE, Bertalan M, Bevilacqua E, Bigdeli TB, Black DW, Bruggeman R, Buccola NG, Buckner RL, Bulik-Sullivan B, Byerley W, Cahn W, Cai G, Cairns MJ, Campion D, Cantor RM, Carr VJ, Carrera N, Catts SV, Chambert KD, Cheng W, Cloninger CR, Cohen D, Cormican P, Craddock N, Crespo-Facorro B, Crowley JJ, Curtis D, Davidson M, Davis KL, Degenhardt F, Del Favero J, DeLisi LE, Dikeos D, Dinan T, Djurovic S, Donohoe G, Drapeau E, Duan J, Dudbridge F, Eichhammer P, Eriksson J, Escott-Price V, Essioux L, Fanous AH, Farh KH, Farrell MS, Frank J, Franke L, Freedman R, Freimer NB, Friedman JI, Forstner AJ, Fromer M, Genovese G, Georgieva L, Gershon ES, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, Gratten J, de Haan L, Hamshere ML, Hansen M, Hansen T, Haroutunian V, Hartmann AM, Henskens FA, Herms S, Hirschhorn JN, Hoffmann P, Hofman A, Huang H, Ikeda M, Joa I, Kähler AK, Kahn RS, Kalaydjieva L, Karjalainen J, Kavanagh D, Keller MC, Kelly BJ, Kennedy JL, Kim Y, Knowles JA, Konte B, Laurent C, Lee P, Lee SH, Legge SE, Lerer B, Levy DL, Liang KY, Lieberman J, Lönnqvist J, Loughland CM, Magnusson PKE, Maher BS, Maier W, Mallet J, Mattheisen M, Mattingsdal M, McCarley RW, McDonald C, McIntosh AM, Meier S, Meijer CJ, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mokrab Y, Morris DW, Müller-Myhsok B, Murphy KC, Murray RM, Myin-Germeys I, Nenadic I, Nertney DA, Nestadt G, Nicodemus KK, Nisenbaum L, Nordin A, O'Callaghan E, O'Dushlaine C, Oh SY, Olincy A, Olsen L, O'Neill FA, Van Os J, Pantelis C, Papadimitriou GN, Parkhomenko E, Pato MT, Paunio T; Psychosis Endophenotypes International Consortium, Perkins DO, Pers TH, Pietiläinen O, Pimm J, Pocklington AJ, Powell J, Price A, Pulver AE, Purcell SM, Quested D, Rasmussen HB, Reichenberg A, Reimers MA, Richards AL, Roffman JL, Roussos P, Ruderfer DM, Salomaa V, Sanders AR, Savitz A, Schall U, Schulze TG, Schwab SG, Scolnick EM, Scott RJ, Seidman LJ, Shi J, Silverman JM, Smoller JW, Söderman E, Spencer CCA, Stahl EA, Strengman E, Strohmaier J, Stroup TS, Suvisaari J, Svrakic DM, Szatkiewicz JP, Thirumalai S, Tooney PA, Veijola J, Visscher PM, Waddington J, Walsh D, Webb BT, Weiser M, Wildenauer DB, Williams NM, Williams S, Witt SH, Wolen AR, Wormley BK, Wray NR, Wu JQ, Zai CC, Adolfsson R, Andreassen OA, Blackwood DHR, Bramon E, Buxbaum JD, Cichon S, Collier DA, Corvin A, Daly MJ, Darvasi A, Domenici E, Esko T, Gejman PV, Gill M, Gurling H, Hultman CM, Iwata N, Jablensky AV, Jönsson EG, Kendler KS, Kirov G, Knight J, Levinson DF, Li QS, McCarroll SA, McQuillin A, Moran JL, Mowry BJ, Nöthen MM, Ophoff RA, Owen MJ, Palotie A, Pato CN, Petryshen TL, Posthuma D, Rietschel M, Riley BP, Rujescu D, Sklar P, St Clair D, Walters JTR, Werge T, Sullivan PF, O'Donovan MC, Scherer SW, Neale BM, Sebat J; CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium.

Nat Genet. 2017 Jan;49(1):27-35. doi: 10.1038/ng.3725. Epub 2016 Nov 21. Erratum in: Nat Genet. 2017 Mar 30;49(4):651. Nat Genet. 2017 Sep 27;49(10 ):1558.

22.

Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease.

Wang M, Roussos P, McKenzie A, Zhou X, Kajiwara Y, Brennand KJ, De Luca GC, Crary JF, Casaccia P, Buxbaum JD, Ehrlich M, Gandy S, Goate A, Katsel P, Schadt E, Haroutunian V, Zhang B.

Genome Med. 2016 Nov 1;8(1):104.

23.

Gene expression elucidates functional impact of polygenic risk for schizophrenia.

Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gümüş ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T, Fullard JF, Wang YC, Mahajan MC, Derry JM, Dudley JT, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn CG, Lewis DA, Haroutunian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hirai K, Roeder K, Brennand KJ, Katsanis N, Domenici E, Devlin B, Sklar P.

Nat Neurosci. 2016 Nov;19(11):1442-1453. doi: 10.1038/nn.4399. Epub 2016 Sep 26.

24.

Altered fucosyltransferase expression in the superior temporal gyrus of elderly patients with schizophrenia.

Mueller TM, Yates SD, Haroutunian V, Meador-Woodruff JH.

Schizophr Res. 2017 Apr;182:66-73. doi: 10.1016/j.schres.2016.10.024. Epub 2016 Oct 20.

25.

Shaping plasticity: Alterations in glutamate transporter localization as a pathophysiological mechanism in severe mental illness.

McCullumsmith RE, O'Donovan SM, Drummond JB, Benesh FS, Simmons M, Roberts R, Lauriat T, Haroutunian V, Meador-Woodruff JH.

Mol Psychiatry. 2016 Jun;21(6):723. doi: 10.1038/mp.2016.79. No abstract available.

PMID:
27198660
26.

Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain.

Scheckel C, Drapeau E, Frias MA, Park CY, Fak J, Zucker-Scharff I, Kou Y, Haroutunian V, Ma'ayan A, Buxbaum JD, Darnell RB.

Elife. 2016 Feb 19;5. pii: e10421. doi: 10.7554/eLife.10421.

27.

Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia.

Pinner AL, Tucholski J, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH.

Schizophr Res. 2016 Nov;177(1-3):78-87. doi: 10.1016/j.schres.2016.01.054. Epub 2016 Feb 11.

28.

Understanding the genetic liability to schizophrenia through the neuroepigenome.

Fullard JF, Halene TB, Giambartolomei C, Haroutunian V, Akbarian S, Roussos P.

Schizophr Res. 2016 Nov;177(1-3):115-124. doi: 10.1016/j.schres.2016.01.039. Epub 2016 Jan 27. Review.

29.

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease.

Watson CT, Roussos P, Garg P, Ho DJ, Azam N, Katsel PL, Haroutunian V, Sharp AJ.

Genome Med. 2016 Jan 19;8(1):5. doi: 10.1186/s13073-015-0258-8.

30.

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory.

Fá M, Puzzo D, Piacentini R, Staniszewski A, Zhang H, Baltrons MA, Li Puma DD, Chatterjee I, Li J, Saeed F, Berman HL, Ripoli C, Gulisano W, Gonzalez J, Tian H, Costa JA, Lopez P, Davidowitz E, Yu WH, Haroutunian V, Brown LM, Palmeri A, Sigurdsson EM, Duff KE, Teich AF, Honig LS, Sierks M, Moe JG, D'Adamio L, Grassi C, Kanaan NM, Fraser PE, Arancio O.

Sci Rep. 2016 Jan 20;6:19393. doi: 10.1038/srep19393.

31.

Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.

Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME.

Mol Psychiatry. 2016 Aug;21(8):1153-4. doi: 10.1038/mp.2015.215. Epub 2016 Jan 19. No abstract available.

PMID:
26782051
32.

Decreased expression of cortactin in the schizophrenia brain.

Bhambhvani HP, Simmons M, Haroutunian V, Meador-Woodruff JH.

Neuroreport. 2016 Feb 10;27(3):145-50. doi: 10.1097/WNR.0000000000000514.

33.

Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.

Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME.

Mol Psychiatry. 2016 Aug;21(8):1099-111. doi: 10.1038/mp.2015.167. Epub 2015 Nov 10. Erratum in: Mol Psychiatry. 2016 Aug;21(8):1153-4.

34.

Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons?

McCullumsmith RE, O'Donovan SM, Drummond JB, Benesh FS, Simmons M, Roberts R, Lauriat T, Haroutunian V, Meador-Woodruff JH.

Mol Psychiatry. 2016 Jun;21(6):823-30. doi: 10.1038/mp.2015.148. Epub 2015 Sep 29.

PMID:
26416546
35.

Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis.

Zhu L, Zhong M, Elder GA, Sano M, Holtzman DM, Gandy S, Cardozo C, Haroutunian V, Robakis NK, Cai D.

Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11965-70. doi: 10.1073/pnas.1510011112. Epub 2015 Sep 8.

36.

Abnormal subcellular localization of GABAA receptor subunits in schizophrenia brain.

Mueller TM, Remedies CE, Haroutunian V, Meador-Woodruff JH.

Transl Psychiatry. 2015 Aug 4;5:e612. doi: 10.1038/tp.2015.102.

37.

Protein Expression of Proteasome Subunits in Elderly Patients with Schizophrenia.

Scott MR, Rubio MD, Haroutunian V, Meador-Woodruff JH.

Neuropsychopharmacology. 2016 Feb;41(3):896-905. doi: 10.1038/npp.2015.219. Epub 2015 Jul 23.

38.

Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophrenia.

Kippe JM, Mueller TM, Haroutunian V, Meador-Woodruff JH.

Schizophr Res. 2015 Aug;166(1-3):219-24. doi: 10.1016/j.schres.2015.06.002. Epub 2015 Jun 20.

39.

Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia.

O'Donovan SM, Hasselfeld K, Bauer D, Simmons M, Roussos P, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Transl Psychiatry. 2015 Jun 9;5:e579. doi: 10.1038/tp.2015.74.

40.

Decreased chloride channel expression in the dorsolateral prefrontal cortex in schizophrenia.

Sullivan CR, Funk AJ, Shan D, Haroutunian V, McCullumsmith RE.

PLoS One. 2015 Mar 31;10(3):e0123158. doi: 10.1371/journal.pone.0123158. eCollection 2015.

41.

Impaired mitochondrial energy metabolism as a novel risk factor for selective onset and progression of dementia in oldest-old subjects.

Zhao W, Wang J, Varghese M, Ho L, Mazzola P, Haroutunian V, Katsel PL, Gibson GE, Levine S, Dubner L, Pasinetti GM.

Neuropsychiatr Dis Treat. 2015 Mar 5;11:565-74. doi: 10.2147/NDT.S74898. eCollection 2015.

42.

Integration of gene expression and GWAS results supports involvement of calcium signaling in Schizophrenia.

Hertzberg L, Katsel P, Roussos P, Haroutunian V, Domany E.

Schizophr Res. 2015 May;164(1-3):92-9. doi: 10.1016/j.schres.2015.02.001. Epub 2015 Feb 20.

PMID:
25702973
43.

Sex differences in GABAergic gene expression occur in the anterior cingulate cortex in schizophrenia.

Bristow GC, Bostrom JA, Haroutunian V, Sodhi MS.

Schizophr Res. 2015 Sep;167(1-3):57-63. doi: 10.1016/j.schres.2015.01.025. Epub 2015 Feb 7.

44.

Erratum: The relationship between dopamine receptor D1 and cognitive performance.

Tsang J, Fullard JF, Giakoumaki SG, Katsel P, Eirini Karagiorga V, Greenwood TA, Braff DL, Siever LJ, Bitsios P, Haroutunian V, Roussos P.

NPJ Schizophr. 2015 Jun 10;1:15018. doi: 10.1038/npjschz.2015.18. eCollection 2015.

45.

The relationship between dopamine receptor D1 and cognitive performance.

Tsang J, Fullard JF, Giakoumaki SG, Katsel P, Katsel P, Karagiorga VE, Greenwood TA, Braff DL, Siever LJ, Bitsios P, Haroutunian V, Roussos P.

NPJ Schizophr. 2015 Mar 4;1:14002. doi: 10.1038/npjschz.2014.2. eCollection 2015. Erratum in: NPJ Schizophr. 2015;1:15018.

46.

The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia.

Roussos P, Katsel P, Fam P, Tan W, Purohit DP, Haroutunian V.

Alzheimers Dement. 2015 Oct;11(10):1163-70. doi: 10.1016/j.jalz.2014.10.013. Epub 2014 Dec 9.

47.

Conserved higher-order chromatin regulates NMDA receptor gene expression and cognition.

Bharadwaj R, Peter CJ, Jiang Y, Roussos P, Vogel-Ciernia A, Shen EY, Mitchell AC, Mao W, Whittle C, Dincer A, Jakovcevski M, Pothula V, Rasmussen TP, Giakoumaki SG, Bitsios P, Sherif A, Gardner PD, Ernst P, Ghose S, Sklar P, Haroutunian V, Tamminga C, Myers RH, Futai K, Wood MA, Akbarian S.

Neuron. 2014 Dec 3;84(5):997-1008. doi: 10.1016/j.neuron.2014.10.032. Epub 2014 Nov 13.

48.

Increased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophrenia.

Funk AJ, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Schizophr Res. 2014 Oct;159(1):130-5. doi: 10.1016/j.schres.2014.07.040. Epub 2014 Aug 19.

49.

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.

Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, Joachim C, Powell J, Lovestone S, Bennett DA, Schalkwyk LC, Mill J.

Nat Neurosci. 2014 Sep;17(9):1164-70. doi: 10.1038/nn.3782. Epub 2014 Aug 17.

50.

Pentameric thiophene-based ligands that spectrally discriminate amyloid-β and tau aggregates display distinct solvatochromism and viscosity-induced spectral shifts.

Simon RA, Shirani H, Aslund KO, Bäck M, Haroutunian V, Gandy S, Nilsson KP.

Chemistry. 2014 Sep 22;20(39):12537-43. doi: 10.1002/chem.201402890. Epub 2014 Aug 8.

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