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Items: 1 to 50 of 104

1.

Overcoming insecticide resistance through computational inhibitor design.

Correy GJ, Zaidman D, Harmelin A, Carvalho S, Mabbitt PD, Calaora V, James PJ, Kotze AC, Jackson CJ, London N.

Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21012-21021. doi: 10.1073/pnas.1909130116. Epub 2019 Oct 1.

PMID:
31575743
2.

Potential roles of gut microbiome and metabolites in modulating ALS in mice.

Blacher E, Bashiardes S, Shapiro H, Rothschild D, Mor U, Dori-Bachash M, Kleimeyer C, Moresi C, Harnik Y, Zur M, Zabari M, Brik RB, Kviatcovsky D, Zmora N, Cohen Y, Bar N, Levi I, Amar N, Mehlman T, Brandis A, Biton I, Kuperman Y, Tsoory M, Alfahel L, Harmelin A, Schwartz M, Israelson A, Arike L, Johansson MEV, Hansson GC, Gotkine M, Segal E, Elinav E.

Nature. 2019 Aug;572(7770):474-480. doi: 10.1038/s41586-019-1443-5. Epub 2019 Jul 22.

PMID:
31330533
3.

IL-23-producing IL-10Rα-deficient gut macrophages elicit an IL-22-driven proinflammatory epithelial cell response.

Bernshtein B, Curato C, Ioannou M, Thaiss CA, Gross-Vered M, Kolesnikov M, Wang Q, David E, Chappell-Maor L, Harmelin A, Elinav E, Thakker P, Papayannopoulos V, Jung S.

Sci Immunol. 2019 Jun 14;4(36). pii: eaau6571. doi: 10.1126/sciimmunol.aau6571.

PMID:
31201258
4.

Combined laser speckle imaging and fluorescent intravital microscopy for monitoring acute vascular permeability reaction.

Kalchenko V, Meglinski I, Sdobnov A, Kuznetsov Y, Harmelin A.

J Biomed Opt. 2019 May;24(6):1-4. doi: 10.1117/1.JBO.24.6.060501.

5.

The Likelihood of Misidentifying Rodent Pasteurellaceae by Using Results from a Single PCR Assay.

Dafni H, Greenfeld L, Oren R, Harmelin A.

J Am Assoc Lab Anim Sci. 2019 Mar 1;58(2):201-207. doi: 10.30802/AALAS-JAALAS-18-000049. Epub 2019 Jan 16.

6.

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT.

Suez J, Zmora N, Zilberman-Schapira G, Mor U, Dori-Bachash M, Bashiardes S, Zur M, Regev-Lehavi D, Ben-Zeev Brik R, Federici S, Horn M, Cohen Y, Moor AE, Zeevi D, Korem T, Kotler E, Harmelin A, Itzkovitz S, Maharshak N, Shibolet O, Pevsner-Fischer M, Shapiro H, Sharon I, Halpern Z, Segal E, Elinav E.

Cell. 2018 Sep 6;174(6):1406-1423.e16. doi: 10.1016/j.cell.2018.08.047.

7.

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features.

Zmora N, Zilberman-Schapira G, Suez J, Mor U, Dori-Bachash M, Bashiardes S, Kotler E, Zur M, Regev-Lehavi D, Brik RB, Federici S, Cohen Y, Linevsky R, Rothschild D, Moor AE, Ben-Moshe S, Harmelin A, Itzkovitz S, Maharshak N, Shibolet O, Shapiro H, Pevsner-Fischer M, Sharon I, Halpern Z, Segal E, Elinav E.

Cell. 2018 Sep 6;174(6):1388-1405.e21. doi: 10.1016/j.cell.2018.08.041.

8.

Assessing Mucosal Inflammation in a DSS-Induced Colitis Mouse Model by MR Colonography.

Biton IE, Stettner N, Brener O, Erez A, Harmelin A, Garbow JR.

Tomography. 2018 Mar;4(1):4-13. doi: 10.18383/j.tom.2017.00021.

9.

Induction of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and Inflammation-Associated Colon Cancer.

Stettner N, Rosen C, Bernshtein B, Gur-Cohen S, Frug J, Silberman A, Sarver A, Carmel-Neiderman NN, Eilam R, Biton I, Pevsner-Fischer M, Zmora N, Brandis A, Bahar Halpern K, Mazkereth R, di Bernardo D, Brunetti-Pierri N, Premkumar MH, Dank G, Nagamani SCS, Jung S, Harmelin A, Erez A.

Cell Rep. 2018 May 15;23(7):1962-1976. doi: 10.1016/j.celrep.2018.04.053.

10.

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection.

Thaiss CA, Levy M, Grosheva I, Zheng D, Soffer E, Blacher E, Braverman S, Tengeler AC, Barak O, Elazar M, Ben-Zeev R, Lehavi-Regev D, Katz MN, Pevsner-Fischer M, Gertler A, Halpern Z, Harmelin A, Aamar S, Serradas P, Grosfeld A, Shapiro H, Geiger B, Elinav E.

Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8.

PMID:
29519916
11.

Regulatory Forum Opinion Piece*: Imaging Applications in Toxicologic Pathology-Recommendations for Use in Regulated Nonclinical Toxicity Studies.

Maronpot RR, Nyska A, Troth SP, Gabrielson K, Sysa-Shah P, Kalchenko V, Kuznetsov Y, Harmelin A, Schiffenbauer YS, Bonnel D, Stauber J, Ramot Y.

Toxicol Pathol. 2017 Jun;45(4):444-471. doi: 10.1177/0192623317710014.

PMID:
28641506
12.

Subcutaneous Compared with Intraperitoneal KetamineXylazine for Anesthesia of Mice.

Levin-Arama M, Abraham L, Waner T, Harmelin A, Steinberg DM, Lahav T, Harlev M.

J Am Assoc Lab Anim Sci. 2016 Nov;55(6):794-800.

13.

Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations.

Thaiss CA, Levy M, Korem T, Dohnalová L, Shapiro H, Jaitin DA, David E, Winter DR, Gury-BenAri M, Tatirovsky E, Tuganbaev T, Federici S, Zmora N, Zeevi D, Dori-Bachash M, Pevsner-Fischer M, Kartvelishvily E, Brandis A, Harmelin A, Shibolet O, Halpern Z, Honda K, Amit I, Segal E, Elinav E.

Cell. 2016 Dec 1;167(6):1495-1510.e12. doi: 10.1016/j.cell.2016.11.003.

14.

Persistent microbiome alterations modulate the rate of post-dieting weight regain.

Thaiss CA, Itav S, Rothschild D, Meijer MT, Levy M, Moresi C, Dohnalová L, Braverman S, Rozin S, Malitsky S, Dori-Bachash M, Kuperman Y, Biton I, Gertler A, Harmelin A, Shapiro H, Halpern Z, Aharoni A, Segal E, Elinav E.

Nature. 2016 Dec 22;540(7634):544-551. doi: 10.1038/nature20796. Epub 2016 Nov 24.

PMID:
27906159
15.

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.

Gury-BenAri M, Thaiss CA, Serafini N, Winter DR, Giladi A, Lara-Astiaso D, Levy M, Salame TM, Weiner A, David E, Shapiro H, Dori-Bachash M, Pevsner-Fischer M, Lorenzo-Vivas E, Keren-Shaul H, Paul F, Harmelin A, Eberl G, Itzkovitz S, Tanay A, Di Santo JP, Elinav E, Amit I.

Cell. 2016 Aug 25;166(5):1231-1246.e13. doi: 10.1016/j.cell.2016.07.043. Epub 2016 Aug 18.

16.

ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.

Ben-Shoshan SO, Kagan P, Sultan M, Barabash Z, Dor C, Jacob-Hirsch J, Harmelin A, Pappo O, Marcu-Malina V, Ben-Ari Z, Amariglio N, Rechavi G, Goldstein I, Safran M.

RNA Biol. 2017 May 4;14(5):587-602. doi: 10.1080/15476286.2016.1203501. Epub 2016 Jun 30.

17.

CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting.

Kuperman Y, Weiss M, Dine J, Staikin K, Golani O, Ramot A, Nahum T, Kühne C, Shemesh Y, Wurst W, Harmelin A, Deussing JM, Eder M, Chen A.

Cell Metab. 2016 Jun 14;23(6):1185-1199. doi: 10.1016/j.cmet.2016.04.017. Epub 2016 May 19.

18.

Genetic manipulation of iron biomineralization enhances MR relaxivity in a ferritin-M6A chimeric complex.

Radoul M, Lewin L, Cohen B, Oren R, Popov S, Davidov G, Vandsburger MH, Harmelin A, Bitton R, Greneche JM, Neeman M, Zarivach R.

Sci Rep. 2016 May 23;6:26550. doi: 10.1038/srep26550.

19.

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.

Levy M, Thaiss CA, Zeevi D, Dohnalová L, Zilberman-Schapira G, Mahdi JA, David E, Savidor A, Korem T, Herzig Y, Pevsner-Fischer M, Shapiro H, Christ A, Harmelin A, Halpern Z, Latz E, Flavell RA, Amit I, Segal E, Elinav E.

Cell. 2015 Dec 3;163(6):1428-43. doi: 10.1016/j.cell.2015.10.048.

20.

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.

Korem T, Zeevi D, Suez J, Weinberger A, Avnit-Sagi T, Pompan-Lotan M, Matot E, Jona G, Harmelin A, Cohen N, Sirota-Madi A, Thaiss CA, Pevsner-Fischer M, Sorek R, Xavier R, Elinav E, Segal E.

Science. 2015 Sep 4;349(6252):1101-1106. doi: 10.1126/science.aac4812. Epub 2015 Jul 30.

21.

A simple approach for non-invasive transcranial optical vascular imaging (nTOVI).

Kalchenko V, Israeli D, Kuznetsov Y, Meglinski I, Harmelin A.

J Biophotonics. 2015 Nov;8(11-12):897-901. doi: 10.1002/jbio.201400140. Epub 2015 Apr 29.

PMID:
25924020
22.

Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis.

Thaiss CA, Zeevi D, Levy M, Zilberman-Schapira G, Suez J, Tengeler AC, Abramson L, Katz MN, Korem T, Zmora N, Kuperman Y, Biton I, Gilad S, Harmelin A, Shapiro H, Halpern Z, Segal E, Elinav E.

Cell. 2014 Oct 23;159(3):514-29. doi: 10.1016/j.cell.2014.09.048. Epub 2014 Oct 16.

23.

Artificial sweeteners induce glucose intolerance by altering the gut microbiota.

Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss CA, Maza O, Israeli D, Zmora N, Gilad S, Weinberger A, Kuperman Y, Harmelin A, Kolodkin-Gal I, Shapiro H, Halpern Z, Segal E, Elinav E.

Nature. 2014 Oct 9;514(7521):181-6. doi: 10.1038/nature13793. Epub 2014 Sep 17.

PMID:
25231862
24.

A simple cage-autonomous method for the maintenance of the barrier status of germ-free mice during experimentation.

Hecht G, Bar-Nathan C, Milite G, Alon I, Moshe Y, Greenfeld L, Dotsenko N, Suez J, Levy M, Thaiss CA, Dafni H, Elinav E, Harmelin A.

Lab Anim. 2014 Oct;48(4):292-7. doi: 10.1177/0023677214544728. Epub 2014 Aug 5.

PMID:
25097255
25.

Transcranial optical vascular imaging (TOVI) of cortical hemodynamics in mouse brain.

Kalchenko V, Israeli D, Kuznetsov Y, Harmelin A.

Sci Rep. 2014 Jul 25;4:5839. doi: 10.1038/srep05839.

26.

Ear swelling test by using laser speckle imaging with a long exposure time.

Kalchenko V, Kuznetsov Y, Preise D, Meglinski I, Harmelin A.

J Biomed Opt. 2014 Jun;19(6):060502. doi: 10.1117/1.JBO.19.6.060502.

27.

Multimodal imaging reveals a role for Akt1 in fetal cardiac development.

Vandoorne K, Vandsburger MH, Weisinger K, Brumfeld V, Hemmings BA, Harmelin A, Neeman M.

Physiol Rep. 2013 Nov;1(6):e00143. doi: 10.1002/phy2.143. Epub 2013 Nov 7.

28.

Man made disease: clinical manifestations of low phenylalanine levels in an inadequately treated phenylketonuria patient and mouse study.

Pode-Shakked B, Shemer-Meiri L, Harmelin A, Stettner N, Brenner O, Abraham S, Schwartz G, Anikster Y.

Mol Genet Metab. 2013;110 Suppl:S66-70. doi: 10.1016/j.ymgme.2013.10.006. Epub 2013 Oct 12.

PMID:
24206931
29.

Chronic Akt1 deficiency attenuates adverse remodeling and enhances angiogenesis after myocardial infarction.

Vandoorne K, Vandsburger MH, Raz T, Shalev M, Weisinger K, Biton I, Brumfeld V, Raanan C, Nevo N, Eilam R, Hemmings BA, Tzahor E, Harmelin A, Gepstein L, Neeman M.

Circ Cardiovasc Imaging. 2013 Nov;6(6):992-1000. doi: 10.1161/CIRCIMAGING.113.000828. Epub 2013 Oct 17.

PMID:
24134954
30.

Label free in vivo laser speckle imaging of blood and lymph vessels.

Kalchenko V, Kuznetsov Y, Meglinski I, Harmelin A.

J Biomed Opt. 2012 May;17(5):050502. doi: 10.1117/1.JBO.17.5.050502.

31.

Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function.

Margalit O, Simon AJ, Yakubov E, Puca R, Yosepovich A, Avivi C, Jacob-Hirsch J, Gelernter I, Harmelin A, Barshack I, Rechavi G, D'Orazi G, Givol D, Amariglio N.

Int J Cancer. 2012 Aug 15;131(4):E562-8. doi: 10.1002/ijc.26441. Epub 2011 Nov 30.

32.

In vivo characterization of tumor and tumor vascular network using multi-modal imaging approach.

Kalchenko V, Madar-Balakirski N, Meglinski I, Harmelin A.

J Biophotonics. 2011 Sep;4(9):645-9. doi: 10.1002/jbio.201100033. Epub 2011 Jun 28.

PMID:
21714099
33.

Survival and size are differentially regulated by placental and fetal PKBalpha/AKT1 in mice.

Plaks V, Berkovitz E, Vandoorne K, Berkutzki T, Damari GM, Haffner R, Dekel N, Hemmings BA, Neeman M, Harmelin A.

Biol Reprod. 2011 Mar;84(3):537-45. doi: 10.1095/biolreprod.110.085951. Epub 2010 Oct 27.

34.

Functional phenotyping of the maternal albumin turnover in the mouse placenta by dynamic contrast-enhanced MRI.

Plaks V, Sapoznik S, Berkovitz E, Haffner-Krausz R, Dekel N, Harmelin A, Neeman M.

Mol Imaging Biol. 2011 Jun;13(3):481-492. doi: 10.1007/s11307-010-0390-1.

35.

Bone vascularization and trabecular bone formation are mediated by PKB alpha/Akt1 in a gene-dosage-dependent manner: in vivo and ex vivo MRI.

Vandoorne K, Magland J, Plaks V, Sharir A, Zelzer E, Wehrli F, Hemmings BA, Harmelin A, Neeman M.

Magn Reson Med. 2010 Jul;64(1):54-64. doi: 10.1002/mrm.22395.

36.

Adenosine-to-inosine RNA editing shapes transcriptome diversity in primates.

Paz-Yaacov N, Levanon EY, Nevo E, Kinar Y, Harmelin A, Jacob-Hirsch J, Amariglio N, Eisenberg E, Rechavi G.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12174-9. doi: 10.1073/pnas.1006183107. Epub 2010 Jun 21.

37.

Ferritin as a reporter gene for MRI: chronic liver over expression of H-ferritin during dietary iron supplementation and aging.

Ziv K, Meir G, Harmelin A, Shimoni E, Klein E, Neeman M.

NMR Biomed. 2010 Jun;23(5):523-31. doi: 10.1002/nbm.1491.

38.

Ferritin nanoparticles as magnetic resonance reporter gene.

Cohen B, Ziv K, Plaks V, Harmelin A, Neeman M.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Mar-Apr;1(2):181-8. doi: 10.1002/wnan.11. Review.

PMID:
20049789
39.

Gonadotropin-regulated lymphangiogenesis in ovarian cancer is mediated by LEDGF-induced expression of VEGF-C.

Sapoznik S, Cohen B, Tzuman Y, Meir G, Ben-Dor S, Harmelin A, Neeman M.

Cancer Res. 2009 Dec 15;69(24):9306-14. doi: 10.1158/0008-5472.CAN-09-1213.

40.

Transcriptional regulation of vascular endothelial growth factor C by oxidative and thermal stress is mediated by lens epithelium-derived growth factor/p75.

Cohen B, Addadi Y, Sapoznik S, Meir G, Kalchenko V, Harmelin A, Ben-Dor S, Neeman M.

Neoplasia. 2009 Sep;11(9):921-33.

41.

Embryonic pig pancreatic tissue for the treatment of diabetes in a nonhuman primate model.

Hecht G, Eventov-Friedman S, Rosen C, Shezen E, Tchorsh D, Aronovich A, Freud E, Golan H, El-Hasid R, Katchman H, Hering BJ, Zung A, Kra-Oz Z, Shaked-Mishan P, Yusim A, Shtabsky A, Idelevitch P, Tobar A, Harmelin A, Bachar-Lustig E, Reisner Y.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8659-64. doi: 10.1073/pnas.0812253106. Epub 2009 May 11.

42.

Interspecies comparison of prostate cancer gene-expression profiles reveals genes associated with aggressive tumors.

Kela I, Harmelin A, Waks T, Orr-Urtreger A, Domany E, Eshhar Z.

Prostate. 2009 Jul 1;69(10):1034-44. doi: 10.1002/pros.20950.

PMID:
19343735
43.

Anti-inflammatory effects of an inflammatory chemokine: CCL2 inhibits lymphocyte homing by modulation of CCL21-triggered integrin-mediated adhesions.

Flaishon L, Hart G, Zelman E, Moussion C, Grabovsky V, Lapidot Tal G, Feigelson S, Margalit R, Harmelin A, Avin-Wittenberg T, Shoseyov D, Alon R, Girard JP, Shachar I.

Blood. 2008 Dec 15;112(13):5016-25. doi: 10.1182/blood-2007-12-129122. Epub 2008 Sep 18.

PMID:
18802011
44.

Cell lineage analysis of a mouse tumor.

Frumkin D, Wasserstrom A, Itzkovitz S, Stern T, Harmelin A, Eilam R, Rechavi G, Shapiro E.

Cancer Res. 2008 Jul 15;68(14):5924-31. doi: 10.1158/0008-5472.CAN-07-6216.

45.

Estimating cell depth from somatic mutations.

Wasserstrom A, Frumkin D, Adar R, Itzkovitz S, Stern T, Kaplan S, Shefer G, Shur I, Zangi L, Reizel Y, Harmelin A, Dor Y, Dekel N, Reisner Y, Benayahu D, Tzahor E, Segal E, Shapiro E.

PLoS Comput Biol. 2008 May 9;4(4):e1000058. doi: 10.1371/journal.pcbi.1000058.

46.

Reconstruction of cell lineage trees in mice.

Wasserstrom A, Adar R, Shefer G, Frumkin D, Itzkovitz S, Stern T, Shur I, Zangi L, Kaplan S, Harmelin A, Reisner Y, Benayahu D, Tzahor E, Segal E, Shapiro E.

PLoS One. 2008 Apr 9;3(4):e1939. doi: 10.1371/journal.pone.0001939.

47.

Amplification of multiple genomic loci from single cells isolated by laser micro-dissection of tissues.

Frumkin D, Wasserstrom A, Itzkovitz S, Harmelin A, Rechavi G, Shapiro E.

BMC Biotechnol. 2008 Feb 20;8:17. doi: 10.1186/1472-6750-8-17.

48.

Irradiation enhances the metastatic potential of prostatic small cell carcinoma xenografts.

Agemy L, Harmelin A, Waks T, Leibovitch I, Rabin T, Pfeffer MR, Eshhar Z.

Prostate. 2008 Apr 1;68(5):530-9. doi: 10.1002/pros.20702.

PMID:
18247403
49.

In vivo dynamic light scattering imaging of blood coagulation.

Kalchenko V, Brill A, Bayewitch M, Fine I, Zharov V, Galanzha E, Tuchin V, Harmelin A.

J Biomed Opt. 2007 Sep-Oct;12(5):052002.

50.

In vivo dynamic light scattering microscopy of tumour blood vessels.

Kalchenko V, Preise D, Bayewitch M, Fine I, Burd K, Harmelin A.

J Microsc. 2007 Nov;228(Pt 2):118-22.

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