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Items: 1 to 50 of 51

1.

Identification and validation of two peptide markers for the recognition of Clostridioides difficile MLST-1 and MLST-11 by MALDI-MS.

Corver J, Sen J, Hornung BVH, Mertens BJ, Berssenbrugge EKL, Harmanus C, Sanders IMJG, Kumar N, Lawley TD, Kuijper EJ, Hensbergen PJ, Nicolardi S.

Clin Microbiol Infect. 2019 Jul;25(7):904.e1-904.e7. doi: 10.1016/j.cmi.2018.10.008. Epub 2018 Oct 26.

PMID:
31130255
2.

Clostridium difficile in wild rodents and insectivores in the Netherlands.

Krijger IM, Meerburg BG, Harmanus C, Burt SA.

Lett Appl Microbiol. 2019 Jul;69(1):35-40. doi: 10.1111/lam.13159. Epub 2019 May 2.

3.

Detection of Clostridium difficile in the environment in a veterinary teaching hospital.

Villagómez-Estrada S, Blanco JL, Melo-Duran D, Martín C, Harmanus C, Kuijper EJ, García ME.

Anaerobe. 2019 Jun;57:55-58. doi: 10.1016/j.anaerobe.2019.03.011. Epub 2019 Mar 18.

PMID:
30898637
4.

Characterization of the virulence of a non-RT027, non-RT078 and binary toxin-positive Clostridium difficile strain associated with severe diarrhea.

Li C, Harmanus C, Zhu D, Meng X, Wang S, Duan J, Liu S, Fu C, Zhou P, Liu R, Wu A, Kuijper EJ, Smits WK, Fu L, Sun X.

Emerg Microbes Infect. 2018 Dec 12;7(1):211. doi: 10.1038/s41426-018-0211-1.

6.

Distribution and tracking of Clostridium difficile and Clostridium perfringens in a free-range pig abattoir and processing plant.

Álvarez-Pérez S, Blanco JL, Astorga RJ, Gómez-Laguna J, Barrero-Domínguez B, Galán-Relaño A, Harmanus C, Kuijper E, García ME.

Food Res Int. 2018 Nov;113:456-464. doi: 10.1016/j.foodres.2018.07.040. Epub 2018 Jul 30.

PMID:
30195542
7.

Wild mice in and around the city of Utrecht, the Netherlands, are carriers of Clostridium difficile but not ESBL-producing Enterobacteriaceae, Salmonella spp. or MRSA.

Burt SA, Meijer K, Burggraaff P, Kamerich WS, Harmanus C.

Lett Appl Microbiol. 2018 Nov;67(5):513-519. doi: 10.1111/lam.13066. Epub 2018 Sep 19.

PMID:
30144118
8.

First molecular characterisation and PCR ribotyping of Clostridium difficile strains isolated in two Algerian Hospitals.

Djebbar A, Sebaihia M, Kuijper E, Harmanus C, Sanders I, Benbraham N, Hacène H.

J Infect Dev Ctries. 2018 Jan 31;12(1):15-21. doi: 10.3855/jidc.9580.

9.

Ribotype 078 Clostridium difficile infection incidence in Dutch hospitals is not associated with provincial pig farming: Results from a national sentinel surveillance, 2009-2015.

van Dorp SM, de Greeff SC, Harmanus C, Sanders IMJG, Dekkers OM, Knetsch CW, Kampinga GA, Notermans DW, Kuijper EJ.

PLoS One. 2017 Dec 29;12(12):e0189183. doi: 10.1371/journal.pone.0189183. eCollection 2017.

10.

A helicase-containing module defines a family of pCD630-like plasmids in Clostridium difficile.

Smits WK, Weese JS, Roberts AP, Harmanus C, Hornung B.

Anaerobe. 2018 Feb;49:78-84. doi: 10.1016/j.anaerobe.2017.12.005. Epub 2017 Dec 12.

11.

Zoonotic Transfer of Clostridium difficile Harboring Antimicrobial Resistance between Farm Animals and Humans.

Knetsch CW, Kumar N, Forster SC, Connor TR, Browne HP, Harmanus C, Sanders IM, Harris SR, Turner L, Morris T, Perry M, Miyajima F, Roberts P, Pirmohamed M, Songer JG, Weese JS, Indra A, Corver J, Rupnik M, Wren BW, Riley TV, Kuijper EJ, Lawley TD.

J Clin Microbiol. 2018 Feb 22;56(3). pii: e01384-17. doi: 10.1128/JCM.01384-17. Print 2018 Mar.

12.

PCR-ribotype distribution of Clostridium difficile in Irish pigs.

Stein K, Egan S, Lynch H, Harmanus C, Kyne L, Herra C, McDermott S, Kuijper E, Fitzpatrick F, FitzGerald S, Fenelon L, Drudy D.

Anaerobe. 2017 Dec;48:237-241. doi: 10.1016/j.anaerobe.2017.10.004. Epub 2017 Oct 9.

PMID:
29024758
13.

An outbreak of Clostridium difficile infections due to new PCR ribotype 826: epidemiologic and microbiologic analyses.

Crobach MJT, Voor In 't Holt AF, Knetsch CW, van Dorp SM, Bras W, Harmanus C, Kuijper EJ, Vos MC.

Clin Microbiol Infect. 2018 Mar;24(3):309.e1-309.e4. doi: 10.1016/j.cmi.2017.08.014. Epub 2017 Aug 19.

14.

Data from a survey of Clostridium perfringens and Clostridium difficile shedding by dogs and cats in the Madrid region (Spain), including phenotypic and genetic characteristics of recovered isolates.

Álvarez-Pérez S, Blanco JL, Harmanus C, Kuijper EJ, García ME.

Data Brief. 2017 Jul 15;14:88-100. doi: 10.1016/j.dib.2017.07.029. eCollection 2017 Oct.

15.

Prevalence and characteristics of Clostridium perfringens and Clostridium difficile in dogs and cats attended in diverse veterinary clinics from the Madrid region.

Álvarez-Pérez S, Blanco JL, Harmanus C, Kuijper EJ, García ME.

Anaerobe. 2017 Dec;48:47-55. doi: 10.1016/j.anaerobe.2017.06.023. Epub 2017 Jul 5.

PMID:
28687280
16.

Recreational sandboxes for children and dogs can be a source of epidemic ribotypes of Clostridium difficile.

Orden C, Neila C, Blanco JL, Álvarez-Pérez S, Harmanus C, Kuijper EJ, García ME.

Zoonoses Public Health. 2018 Feb;65(1):88-95. doi: 10.1111/zph.12374. Epub 2017 Jul 7.

PMID:
28686001
17.

Molecular typing and antimicrobial susceptibility testing to six antimicrobials of Clostridium difficile isolates from three Czech hospitals in Eastern Bohemia in 2011-2012.

Beran V, Kuijper EJ, Harmanus C, Sanders IM, van Dorp SM, Knetsch CW, Janeckova J, Seidelova A, Barekova L, Tvrdik J, Chmelar D, Ciznar I.

Folia Microbiol (Praha). 2017 Sep;62(5):445-451. doi: 10.1007/s12223-017-0515-x. Epub 2017 Mar 22.

PMID:
28332133
18.

Occurrence of Clostridium difficile ribotype 027 in hospitals of Silesia, Poland.

Aptekorz M, Szczegielniak A, Wiechuła B, Harmanus C, Kuijper E, Martirosian G.

Anaerobe. 2017 Jun;45:106-113. doi: 10.1016/j.anaerobe.2017.02.002. Epub 2017 Feb 12.

PMID:
28216085
19.

Subtyping and antimicrobial susceptibility of Clostridium difficile PCR ribotype 078/126 isolates of human and animal origin.

Álvarez-Pérez S, Blanco JL, Harmanus C, Kuijper E, García ME.

Vet Microbiol. 2017 Feb;199:15-22. doi: 10.1016/j.vetmic.2016.12.001. Epub 2016 Dec 5.

PMID:
28110780
20.

Isolation of Clostridium difficile from dogs with digestive disorders, including stable metronidazole-resistant strains.

Orden C, Blanco JL, Álvarez-Pérez S, Garcia-Sancho M, Rodriguez-Franco F, Sainz A, Villaescusa A, Harmanus C, Kuijper E, Garcia ME.

Anaerobe. 2017 Feb;43:78-81. doi: 10.1016/j.anaerobe.2016.12.008. Epub 2016 Dec 11.

PMID:
27965048
21.

Toxigenic Clostridium difficile PCR ribotypes in edible marine bivalve molluscs in Italy.

Troiano T, Harmanus C, Sanders IM, Pasquale V, Dumontet S, Capuano F, Romano V, Kuijper EJ.

Int J Food Microbiol. 2015 Sep 2;208:30-4. doi: 10.1016/j.ijfoodmicro.2015.05.002. Epub 2015 May 11.

PMID:
26022983
22.

Development and validation of an internationally-standardized, high-resolution capillary gel-based electrophoresis PCR-ribotyping protocol for Clostridium difficile.

Fawley WN, Knetsch CW, MacCannell DR, Harmanus C, Du T, Mulvey MR, Paulick A, Anderson L, Kuijper EJ, Wilcox MH.

PLoS One. 2015 Feb 13;10(2):e0118150. doi: 10.1371/journal.pone.0118150. eCollection 2015.

23.

Faecal shedding of antimicrobial-resistant Clostridium difficile strains by dogs.

Álvarez-Pérez S, Blanco JL, Peláez T, Lanzarot MP, Harmanus C, Kuijper E, García ME.

J Small Anim Pract. 2015 Mar;56(3):190-5. doi: 10.1111/jsap.12311. Epub 2014 Dec 5.

PMID:
25483272
24.

Occurrence of Clostridium difficile PCR-ribotype 027 and it's closely related PCR-ribotype 176 in hospitals in Poland in 2008-2010.

Obuch-Woszczatyński P, Lachowicz D, Schneider A, Mól A, Pawłowska J, Ożdżeńska-Milke E, Pruszczyk P, Wultańska D, Młynarczyk G, Harmanus C, Kuijper EJ, van Belkum A, Pituch H.

Anaerobe. 2014 Aug;28:13-7. doi: 10.1016/j.anaerobe.2014.04.007. Epub 2014 May 2.

PMID:
24799338
25.

Increased incidence of Clostridium difficile PCR ribotype 027 in Hesse, Germany, 2011 to 2013.

Arvand M, Vollandt D, Bettge-Weller G, Harmanus C, Kuijper EJ; Clostridium difficile study group Hesse.

Euro Surveill. 2014 Mar 13;19(10). pii: 20732.

26.

Shedding of Clostridium difficile PCR ribotype 078 by zoo animals, and report of an unstable metronidazole-resistant isolate from a zebra foal (Equus quagga burchellii).

Álvarez-Pérez S, Blanco JL, Martínez-Nevado E, Peláez T, Harmanus C, Kuijper E, García ME.

Vet Microbiol. 2014 Mar 14;169(3-4):218-22. doi: 10.1016/j.vetmic.2013.12.018. Epub 2014 Jan 4.

PMID:
24467928
27.

High prevalence of the epidemic Clostridium difficile PCR ribotype 078 in Iberian free-range pigs.

Álvarez-Pérez S, Blanco JL, Peláez T, Astorga RJ, Harmanus C, Kuijper E, García ME.

Res Vet Sci. 2013 Oct;95(2):358-61. doi: 10.1016/j.rvsc.2013.06.021. Epub 2013 Jul 19.

PMID:
23876331
28.

Clostridium difficile infection associated with pig farms.

Keessen EC, Harmanus C, Dohmen W, Kuijper EJ, Lipman LJ.

Emerg Infect Dis. 2013 Jun;19(6):1032-4. doi: 10.3201/eid1906.121645. No abstract available.

29.

Emergence of Clostridium difficile infection in tuberculosis patients due to a highly rifampicin-resistant PCR ribotype 046 clone in Poland.

Obuch-Woszczatyński P, Dubiel G, Harmanus C, Kuijper E, Duda U, Wultańska D, van Belkum A, Pituch H.

Eur J Clin Microbiol Infect Dis. 2013 Aug;32(8):1027-30. doi: 10.1007/s10096-013-1845-5. Epub 2013 Feb 27.

30.

Analysis of a Clostridium difficile PCR ribotype 078 100 kilobase island reveals the presence of a novel transposon, Tn6164.

Corver J, Bakker D, Brouwer MS, Harmanus C, Hensgens MP, Roberts AP, Lipman LJ, Kuijper EJ, van Leeuwen HC.

BMC Microbiol. 2012 Jul 2;12:130. doi: 10.1186/1471-2180-12-130.

31.

Comparative analysis of an expanded Clostridium difficile reference strain collection reveals genetic diversity and evolution through six lineages.

Knetsch CW, Terveer EM, Lauber C, Gorbalenya AE, Harmanus C, Kuijper EJ, Corver J, van Leeuwen HC.

Infect Genet Evol. 2012 Oct;12(7):1577-85. doi: 10.1016/j.meegid.2012.06.003. Epub 2012 Jun 15.

PMID:
22705462
32.

Clostridium difficile in Dutch animals: their presence, characteristics and similarities with human isolates.

Koene MG, Mevius D, Wagenaar JA, Harmanus C, Hensgens MP, Meetsma AM, Putirulan FF, van Bergen MA, Kuijper EJ.

Clin Microbiol Infect. 2012 Aug;18(8):778-84. doi: 10.1111/j.1469-0691.2011.03651.x. Epub 2011 Sep 15.

33.

Type-specific risk factors and outcome in an outbreak with 2 different Clostridium difficile types simultaneously in 1 hospital.

Goorhuis A, Debast SB, Dutilh JC, van Kinschot CM, Harmanus C, Cannegieter SC, Hagen EC, Kuijper EJ.

Clin Infect Dis. 2011 Nov;53(9):860-9. doi: 10.1093/cid/cir549. Epub 2011 Sep 13.

PMID:
21914851
34.

Genetic markers for Clostridium difficile lineages linked to hypervirulence.

Knetsch CW, Hensgens MP, Harmanus C, van der Bijl MW, Savelkoul PH, Kuijper EJ, Corver J, van Leeuwen HC.

Microbiology. 2011 Nov;157(Pt 11):3113-23. doi: 10.1099/mic.0.051953-0. Epub 2011 Aug 26.

PMID:
21873406
35.

Isolation of the first three cases of Clostridium difficile polymerase chain reaction ribotype 027 in Singapore.

Lim PL, Ling ML, Lee HY, Koh TH, Tan AL, Kuijper EJ, Goh SS, Low BS, Ang LP, Harmanus C, Lin RT, Krishnan P, James L, Lee CE.

Singapore Med J. 2011 May;52(5):361-4.

36.

Characterization and antimicrobial susceptibility of Clostridium difficile strains isolated from adult patients with diarrhoea hospitalized in two university hospitals in Poland, 2004-2006.

Pituch H, Obuch-Woszczatyński P, Wultańska D, Nurzyńska G, Harmanus C, Banaszkiewicz A, Radzikowski A, Łuczak M, van Belkum A, Kuijper E.

J Med Microbiol. 2011 Aug;60(Pt 8):1200-5. doi: 10.1099/jmm.0.029801-0. Epub 2011 Mar 17.

PMID:
21415206
37.

Clostridium difficile infection in an endemic setting in the Netherlands.

Hensgens MP, Goorhuis A, van Kinschot CM, Crobach MJ, Harmanus C, Kuijper EJ.

Eur J Clin Microbiol Infect Dis. 2011 Apr;30(4):587-93. doi: 10.1007/s10096-010-1127-4. Epub 2010 Dec 31.

38.

Prevalence of Clostridium difficile in retailed meat in the Netherlands.

de Boer E, Zwartkruis-Nahuis A, Heuvelink AE, Harmanus C, Kuijper EJ.

Int J Food Microbiol. 2011 Jan 5;144(3):561-4. doi: 10.1016/j.ijfoodmicro.2010.11.007. Epub 2010 Nov 13.

PMID:
21131085
39.

Acquisition of Clostridium difficile by piglets.

Hopman NE, Keessen EC, Harmanus C, Sanders IM, van Leengoed LA, Kuijper EJ, Lipman LJ.

Vet Microbiol. 2011 Apr 21;149(1-2):186-92. doi: 10.1016/j.vetmic.2010.10.013. Epub 2010 Nov 4.

PMID:
21111541
40.

Relatedness of human and animal Clostridium difficile PCR ribotype 078 isolates determined on the basis of multilocus variable-number tandem-repeat analysis and tetracycline resistance.

Bakker D, Corver J, Harmanus C, Goorhuis A, Keessen EC, Fawley WN, Wilcox MH, Kuijper EJ.

J Clin Microbiol. 2010 Oct;48(10):3744-9. doi: 10.1128/JCM.01171-10. Epub 2010 Aug 4.

41.

Molecular characterization of Capnocytophaga canimorsus and other canine Capnocytophaga spp. and assessment by PCR of their frequencies in dogs.

van Dam AP, van Weert A, Harmanus C, Hovius KE, Claas EC, Reubsaet FA.

J Clin Microbiol. 2009 Oct;47(10):3218-25. doi: 10.1128/JCM.01246-09. Epub 2009 Jul 29.

42.

Application of multiple-locus variable-number tandem-repeat analysis to determine clonal spread of toxin A-negative Clostridium difficile in a general hospital in Buenos Aires, Argentina.

Goorhuis A, Legaria MC, van den Berg RJ, Harmanus C, Klaassen CH, Brazier JS, Lumelsky G, Kuijper EJ.

Clin Microbiol Infect. 2009 Dec;15(12):1080-6. doi: 10.1111/j.1469-0691.2009.02759.x. Epub 2009 May 11.

43.

Clostridium difficile PCR ribotype 078 toxinotype V found in diarrhoeal pigs identical to isolates from affected humans.

Debast SB, van Leengoed LA, Goorhuis A, Harmanus C, Kuijper EJ, Bergwerff AA.

Environ Microbiol. 2009 Feb;11(2):505-11. doi: 10.1111/j.1462-2920.2008.01790.x.

PMID:
19196280
44.

Typing Clostridium difficile strains based on tandem repeat sequences.

Zaiss NH, Rupnik M, Kuijper EJ, Harmanus C, Michielsen D, Janssens K, Nübel U.

BMC Microbiol. 2009 Jan 8;9:6. doi: 10.1186/1471-2180-9-6.

45.

Emergence of Clostridium difficile infection due to a new hypervirulent strain, polymerase chain reaction ribotype 078.

Goorhuis A, Bakker D, Corver J, Debast SB, Harmanus C, Notermans DW, Bergwerff AA, Dekker FW, Kuijper EJ.

Clin Infect Dis. 2008 Nov 1;47(9):1162-70. doi: 10.1086/592257.

PMID:
18808358
46.

Emergence of reduced susceptibility to metronidazole in Clostridium difficile.

Baines SD, O'Connor R, Freeman J, Fawley WN, Harmanus C, Mastrantonio P, Kuijper EJ, Wilcox MH.

J Antimicrob Chemother. 2008 Nov;62(5):1046-52. doi: 10.1093/jac/dkn313. Epub 2008 Aug 7.

PMID:
18693234
47.

First confirmed cases of Clostridium difficile PCR ribotype 027 in Norway.

Ingebretsen A, Hansen G, Harmanus C, Kuijper EJ.

Euro Surveill. 2008 Jan 10;13(2). pii: 8011. No abstract available.

48.

First cluster of clindamycin-resistant Clostridium difficile PCR ribotype 027 in Switzerland.

Fenner L, Widmer AF, Stranden A, Conzelmann M, Goorhuis A, Harmanus C, Kuijper EJ, Frei R.

Clin Microbiol Infect. 2008 May;14(5):514-5. doi: 10.1111/j.1469-0691.2008.01989.x. No abstract available.

49.

Clostridium difficile PCR ribotype 078: an emerging strain in humans and in pigs?

Goorhuis A, Debast SB, van Leengoed LA, Harmanus C, Notermans DW, Bergwerff AA, Kuijper EJ.

J Clin Microbiol. 2008 Mar;46(3):1157; author reply 1158. doi: 10.1128/JCM.01536-07. No abstract available.

50.

Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains.

Fawley WN, Freeman J, Smith C, Harmanus C, van den Berg RJ, Kuijper EJ, Wilcox MH.

J Clin Microbiol. 2008 Mar;46(3):954-60. doi: 10.1128/JCM.01764-07. Epub 2008 Jan 23.

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