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Items: 34


Clinical Reasoning: Transient speech deficits in a patient with history of medulloblastoma.

Schulte JD, Hargus G, Canoll P, Sisti MB, Wang TJC, Lignelli A, Lassman AB.

Neurology. 2018 Sep 18;91(12):e1196-e1201. doi: 10.1212/WNL.0000000000006202. No abstract available. Erratum in: Neurology. 2018 Nov 27;91(22):1031.


Intracranial intraaxial cerebral tufted angioma: case report.

D'Amico RS, Zanazzi G, Hargus G, Dyster T, Chan S, Lignelli-Dipple A, Wang TJC, Faust PL, McKhann GM.

J Neurosurg. 2018 Feb;128(2):524-529. doi: 10.3171/2016.10.JNS162207. Epub 2017 Feb 24.


Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein.

Hallmann AL, Araúzo-Bravo MJ, Mavrommatis L, Ehrlich M, Röpke A, Brockhaus J, Missler M, Sterneckert J, Schöler HR, Kuhlmann T, Zaehres H, Hargus G.

Sci Rep. 2017 Mar 3;7:42991. doi: 10.1038/srep42991.


Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors.

Ehrlich M, Mozafari S, Glatza M, Starost L, Velychko S, Hallmann AL, Cui QL, Schambach A, Kim KP, Bachelin C, Marteyn A, Hargus G, Johnson RM, Antel J, Sterneckert J, Zaehres H, Schöler HR, Baron-Van Evercooren A, Kuhlmann T.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2243-E2252. doi: 10.1073/pnas.1614412114. Epub 2017 Feb 28.


Comparative transcriptome analysis in induced neural stem cells reveals defined neural cell identities in vitro and after transplantation into the adult rodent brain.

Hallmann AL, Araúzo-Bravo MJ, Zerfass C, Senner V, Ehrlich M, Psathaki OE, Han DW, Tapia N, Zaehres H, Schöler HR, Kuhlmann T, Hargus G.

Stem Cell Res. 2016 May;16(3):776-81. doi: 10.1016/j.scr.2016.04.015. Epub 2016 Apr 19.


Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein.

Ehrlich M, Hallmann AL, Reinhardt P, Araúzo-Bravo MJ, Korr S, Röpke A, Psathaki OE, Ehling P, Meuth SG, Oblak AL, Murrell JR, Ghetti B, Zaehres H, Schöler HR, Sterneckert J, Kuhlmann T, Hargus G.

Stem Cell Reports. 2015 Jul 14;5(1):83-96. doi: 10.1016/j.stemcr.2015.06.001. Epub 2015 Jul 2.


Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin.

Dorn I, Klich K, Arauzo-Bravo MJ, Radstaak M, Santourlidis S, Ghanjati F, Radke TF, Psathaki OE, Hargus G, Kramer J, Einhaus M, Kim JB, Kögler G, Wernet P, Schöler HR, Schlenke P, Zaehres H.

Haematologica. 2015 Jan;100(1):32-41. doi: 10.3324/haematol.2014.108068. Epub 2014 Oct 17.


Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain.

Hargus G, Ehrlich M, Araúzo-Bravo MJ, Hemmer K, Hallmann AL, Reinhardt P, Kim KP, Adachi K, Santourlidis S, Ghanjati F, Fauser M, Ossig C, Storch A, Kim JB, Schwamborn JC, Sterneckert J, Schöler HR, Kuhlmann T, Zaehres H.

Cell Rep. 2014 Sep 25;8(6):1697-1703. doi: 10.1016/j.celrep.2014.08.014. Epub 2014 Sep 15.


Usefulness of 5-ALA (Gliolan®)-derived PPX fluorescence for demonstrating the extent of infiltration in atypical meningiomas.

Wilbers E, Hargus G, Wölfer J, Stummer W.

Acta Neurochir (Wien). 2014 Oct;156(10):1853-4. doi: 10.1007/s00701-014-2148-z. Epub 2014 Jun 28. No abstract available.


The extracellular matrix glycoprotein tenascin-R regulates neurogenesis during development and in the adult dentate gyrus of mice.

Xu JC, Xiao MF, Jakovcevski I, Sivukhina E, Hargus G, Cui YF, Irintchev A, Schachner M, Bernreuther C.

J Cell Sci. 2014 Feb 1;127(Pt 3):641-52. doi: 10.1242/jcs.137612. Epub 2013 Dec 11.


Human stem cell models of neurodegeneration: a novel approach to study mechanisms of disease development.

Hargus G, Ehrlich M, Hallmann AL, Kuhlmann T.

Acta Neuropathol. 2014 Feb;127(2):151-73. doi: 10.1007/s00401-013-1222-6. Epub 2013 Dec 5. Review.


Bilateral ganglioglioma of the trigeminal nerve in an 83-year-old man.

Hargus G, Bink A, Nagel I, Paulus W, Harder A.

Neuropathology. 2014 Apr;34(2):159-63. doi: 10.1111/neup.12054. Epub 2013 Jul 29.


Cerebellar anaplastic astrocytoma in an adult with neurofibromatosis type 1: case report and review of literature.

Brokinkel B, Schober O, Ewelt C, Heindel W, Hargus G, Stummer W, Holling M, Wölfer J.

J Neurol Surg A Cent Eur Neurosurg. 2013 Dec;74 Suppl 1:e203-6. doi: 10.1055/s-0033-1342938. Epub 2013 May 13.


Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.

Reinhardt P, Schmid B, Burbulla LF, Schöndorf DC, Wagner L, Glatza M, Höing S, Hargus G, Heck SA, Dhingra A, Wu G, Müller S, Brockmann K, Kluba T, Maisel M, Krüger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki OE, Klingauf J, Kuhlmann T, Klewin M, Müller H, Gasser T, Schöler HR, Sterneckert J.

Cell Stem Cell. 2013 Mar 7;12(3):354-67. doi: 10.1016/j.stem.2013.01.008.


Minor cartilage collagens type IX and XI are expressed during embryonic stem cell-derived in vitro chondrogenesis.

Krug D, Klinger M, Haller R, Hargus G, Büning J, Rohwedel J, Kramer J.

Ann Anat. 2013 Jan;195(1):88-97. doi: 10.1016/j.aanat.2012.06.004. Epub 2012 Aug 21.


Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.

Cooper O, Seo H, Andrabi S, Guardia-Laguarta C, Graziotto J, Sundberg M, McLean JR, Carrillo-Reid L, Xie Z, Osborn T, Hargus G, Deleidi M, Lawson T, Bogetofte H, Perez-Torres E, Clark L, Moskowitz C, Mazzulli J, Chen L, Volpicelli-Daley L, Romero N, Jiang H, Uitti RJ, Huang Z, Opala G, Scarffe LA, Dawson VL, Klein C, Feng J, Ross OA, Trojanowski JQ, Lee VM, Marder K, Surmeier DJ, Wszolek ZK, Przedborski S, Krainc D, Dawson TM, Isacson O.

Sci Transl Med. 2012 Jul 4;4(141):141ra90. doi: 10.1126/scitranslmed.3003985.


In vitro generation of three-dimensional substrate-adherent embryonic stem cell-derived neural aggregates for application in animal models of neurological disorders.

Hargus G, Cui YF, Dihné M, Bernreuther C, Schachner M.

Curr Protoc Stem Cell Biol. 2012 May;Chapter 2:Unit 2D.11. doi: 10.1002/9780470151808.sc02d11s21.


Transplanted L1 expressing radial glia and astrocytes enhance recovery after spinal cord injury.

Xu JC, Bernreuther C, Cui YF, Jakovcevski I, Hargus G, Xiao MF, Schachner M.

J Neurotrauma. 2011 Sep;28(9):1921-37. doi: 10.1089/neu.2011.1783. Epub 2011 Aug 31.


Oct4-induced reprogramming is required for adult brain neural stem cell differentiation into midbrain dopaminergic neurons.

Deleidi M, Cooper O, Hargus G, Levy A, Isacson O.

PLoS One. 2011;6(5):e19926. doi: 10.1371/journal.pone.0019926. Epub 2011 May 31.


Development of histocompatible primate-induced pluripotent stem cells for neural transplantation.

Deleidi M, Hargus G, Hallett P, Osborn T, Isacson O.

Stem Cells. 2011 Jul;29(7):1052-63. doi: 10.1002/stem.662.


Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice.

Cui YF, Xu JC, Hargus G, Jakovcevski I, Schachner M, Bernreuther C.

PLoS One. 2011 Mar 18;6(3):e17126. doi: 10.1371/journal.pone.0017126.


Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats.

Hargus G, Cooper O, Deleidi M, Levy A, Lee K, Marlow E, Yow A, Soldner F, Hockemeyer D, Hallett PJ, Osborn T, Jaenisch R, Isacson O.

Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15921-6. doi: 10.1073/pnas.1010209107. Epub 2010 Aug 23.


Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.

Cooper O, Hargus G, Deleidi M, Blak A, Osborn T, Marlow E, Lee K, Levy A, Perez-Torres E, Yow A, Isacson O.

Mol Cell Neurosci. 2010 Nov;45(3):258-66. doi: 10.1016/j.mcn.2010.06.017. Epub 2010 Jul 24.


Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice.

Cui YF, Hargus G, Xu JC, Schmid JS, Shen YQ, Glatzel M, Schachner M, Bernreuther C.

Brain. 2010 Jan;133(Pt 1):189-204. doi: 10.1093/brain/awp290. Epub 2009 Dec 7.


Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors.

Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG, Hargus G, Blak A, Cooper O, Mitalipova M, Isacson O, Jaenisch R.

Cell. 2009 Mar 6;136(5):964-77. doi: 10.1016/j.cell.2009.02.013.


Close homologue of adhesion molecule L1 promotes survival of Purkinje and granule cells and granule cell migration during murine cerebellar development.

Jakovcevski I, Siering J, Hargus G, Karl N, Hoelters L, Djogo N, Yin S, Zecevic N, Schachner M, Irintchev A.

J Comp Neurol. 2009 Apr 10;513(5):496-510. doi: 10.1002/cne.21981.


Chondrocytes derived from mouse embryonic stem cells.

Kramer J, Hegert C, Hargus G, Rohwedel J.

Cytotechnology. 2003 Mar;41(2-3):177-87. doi: 10.1023/A:1024835025011.


Tenascin-R promotes neuronal differentiation of embryonic stem cells and recruitment of host-derived neural precursor cells after excitotoxic lesion of the mouse striatum.

Hargus G, Cui Y, Schmid JS, Xu J, Glatzel M, Schachner M, Bernreuther C.

Stem Cells. 2008 Aug;26(8):1973-84. doi: 10.1634/stemcells.2007-0929. Epub 2008 May 22.


Loss of Sox9 function results in defective chondrocyte differentiation of mouse embryonic stem cells in vitro.

Hargus G, Kist R, Kramer J, Gerstel D, Neitz A, Scherer G, Rohwedel J.

Int J Dev Biol. 2008;52(4):323-32. doi: 10.1387/ijdb.072490gh.


Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum.

Bernreuther C, Dihné M, Johann V, Schiefer J, Cui Y, Hargus G, Schmid JS, Xu J, Kosinski CM, Schachner M.

J Neurosci. 2006 Nov 8;26(45):11532-9.


Derivation and characterization of chondrocytes from embryonic stem cells in vitro.

Kramer J, Hargus G, Rohwedel J.

Methods Mol Biol. 2006;330:171-90.


Ultrastructural analysis of mouse embryonic stem cell-derived chondrocytes.

Kramer J, Klinger M, Kruse C, Faza M, Hargus G, Rohwedel J.

Anat Embryol (Berl). 2005 Oct;210(3):175-85. Epub 2005 Oct 18.


Mouse ES cell lines show a variable degree of chondrogenic differentiation in vitro.

Kramer J, Hegert C, Hargus G, Rohwedel J.

Cell Biol Int. 2005 Feb;29(2):139-46. Epub 2005 Jan 22.


Differentiation plasticity of chondrocytes derived from mouse embryonic stem cells.

Hegert C, Kramer J, Hargus G, Müller J, Guan K, Wobus AM, Müller PK, Rohwedel J.

J Cell Sci. 2002 Dec 1;115(Pt 23):4617-28.

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