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Items: 17


Control of Stimulus-Dependent Responses in Macrophages by SWI/SNF Chromatin Remodeling Complexes.

Gatchalian J, Liao J, Maxwell MB, Hargreaves DC.

Trends Immunol. 2020 Jan 9. pii: S1471-4906(19)30258-3. doi: 10.1016/ [Epub ahead of print] Review.


Tuning the chromatin landscape of embryonic stem cells.

Hargreaves DC.

Stem Cell Investig. 2019 Jul 2;6:16. doi: 10.21037/sci.2019.06.02. eCollection 2019. No abstract available.


Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.

Gao F, Elliott NJ, Ho J, Sharp A, Shokhirev MN, Hargreaves DC.

Mol Cell. 2019 Sep 5;75(5):891-904.e7. doi: 10.1016/j.molcel.2019.06.024. Epub 2019 Jul 30.


A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells.

Gatchalian J, Malik S, Ho J, Lee DS, Kelso TWR, Shokhirev MN, Dixon JR, Hargreaves DC.

Nat Commun. 2018 Dec 3;9(1):5139. doi: 10.1038/s41467-018-07528-9.


Racheting Up Repair.

Gatchalian J, Hargreaves DC.

Immunity. 2018 Oct 16;49(4):577-579. doi: 10.1016/j.immuni.2018.09.012.


Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal.

Marian CA, Stoszko M, Wang L, Leighty MW, de Crignis E, Maschinot CA, Gatchalian J, Carter BC, Chowdhury B, Hargreaves DC, Duvall JR, Crabtree GR, Mahmoudi T, Dykhuizen EC.

Cell Chem Biol. 2018 Dec 20;25(12):1443-1455.e14. doi: 10.1016/j.chembiol.2018.08.004. Epub 2018 Sep 6.


Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.

Kelso TWR, Porter DK, Amaral ML, Shokhirev MN, Benner C, Hargreaves DC.

Elife. 2017 Oct 2;6. pii: e30506. doi: 10.7554/eLife.30506.


TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin.

Miller EL, Hargreaves DC, Kadoch C, Chang CY, Calarco JP, Hodges C, Buenrostro JD, Cui K, Greenleaf WJ, Zhao K, Crabtree GR.

Nat Struct Mol Biol. 2017 Apr;24(4):344-352. doi: 10.1038/nsmb.3384. Epub 2017 Feb 27.


BAF complexes facilitate decatenation of DNA by topoisomerase II╬▒.

Dykhuizen EC, Hargreaves DC, Miller EL, Cui K, Korshunov A, Kool M, Pfister S, Cho YJ, Zhao K, Crabtree GR.

Nature. 2013 May 30;497(7451):624-7. doi: 10.1038/nature12146. Epub 2013 May 22.


Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.

Kadoch C, Hargreaves DC, Hodges C, Elias L, Ho L, Ranish J, Crabtree GR.

Nat Genet. 2013 Jun;45(6):592-601. doi: 10.1038/ng.2628. Epub 2013 May 5.


ATP-dependent chromatin remodeling: genetics, genomics and mechanisms.

Hargreaves DC, Crabtree GR.

Cell Res. 2011 Mar;21(3):396-420. doi: 10.1038/cr.2011.32. Epub 2011 Mar 1. Review.


Control of inducible gene expression by signal-dependent transcriptional elongation.

Hargreaves DC, Horng T, Medzhitov R.

Cell. 2009 Jul 10;138(1):129-45. doi: 10.1016/j.cell.2009.05.047.


Gene-specific control of inflammation by TLR-induced chromatin modifications.

Foster SL, Hargreaves DC, Medzhitov R.

Nature. 2007 Jun 21;447(7147):972-8. Epub 2007 May 30. Erratum in: Nature. 2008 Jan 3;451(7174):102.


Innate sensors of microbial infection.

Hargreaves DC, Medzhitov R.

J Clin Immunol. 2005 Nov;25(6):503-10. Review.


Traffic patterns of B cells and plasma cells.

Cyster JG, Ansel KM, Ngo VN, Hargreaves DC, Lu TT.

Adv Exp Med Biol. 2002;512:35-41. Review. No abstract available.


Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis.

Luther SA, Bidgol A, Hargreaves DC, Schmidt A, Xu Y, Paniyadi J, Matloubian M, Cyster JG.

J Immunol. 2002 Jul 1;169(1):424-33.


A coordinated change in chemokine responsiveness guides plasma cell movements.

Hargreaves DC, Hyman PL, Lu TT, Ngo VN, Bidgol A, Suzuki G, Zou YR, Littman DR, Cyster JG.

J Exp Med. 2001 Jul 2;194(1):45-56.

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