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Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms.

Moore EC, Sun L, Clavijo PE, Friedman J, Harford JB, Saleh AD, Van Waes C, Chang EH, Allen CT.

Oncoimmunology. 2018 May 7;7(7):e1404216. doi: 10.1080/2162402X.2017.1404216. eCollection 2018.


Targeted nanocomplex carrying siRNA against MALAT1 sensitizes glioblastoma to temozolomide.

Kim SS, Harford JB, Moghe M, Rait A, Pirollo KF, Chang EH.

Nucleic Acids Res. 2018 Feb 16;46(3):1424-1440. doi: 10.1093/nar/gkx1221.


Nanotherapeutics for Gene Modulation that Prevents Apoptosis in the Brain and Fatal Neuroinflammation.

Kim SS, Rait A, Garrido-Sanabria ER, Pirollo KF, Harford JB, Chang EH.

Mol Ther. 2018 Jan 3;26(1):84-94. doi: 10.1016/j.ymthe.2017.10.003. Epub 2017 Oct 10.


Nanomedicine: Past, present and future - A global perspective.

Chang EH, Harford JB, Eaton MA, Boisseau PM, Dube A, Hayeshi R, Swai H, Lee DS.

Biochem Biophys Res Commun. 2015 Dec 18;468(3):511-7. doi: 10.1016/j.bbrc.2015.10.136. Epub 2015 Oct 28. Review.


Breast cancer by age at diagnosis in the Gharbiah, Egypt, population-based registry compared to the United States Surveillance, Epidemiology, and End Results Program, 2004-2008.

Schlichting JA, Soliman AS, Schairer C, Harford JB, Hablas A, Ramadan M, Seifeldin I, Merajver SD.

Biomed Res Int. 2015;2015:381574. doi: 10.1155/2015/381574. Epub 2015 Oct 1.


Barriers to overcome for effective cancer control in Africa.

Harford JB.

Lancet Oncol. 2015 Aug;16(8):e385-93. doi: 10.1016/S1470-2045(15)00160-6. Review.


Effective treatment of glioblastoma requires crossing the blood-brain barrier and targeting tumors including cancer stem cells: The promise of nanomedicine.

Kim SS, Harford JB, Pirollo KF, Chang EH.

Biochem Biophys Res Commun. 2015 Dec 18;468(3):485-9. doi: 10.1016/j.bbrc.2015.06.137. Epub 2015 Jun 24. Review.


Sorting reality from what we think we know about breast cancer in Africa.

Mohammed SI, Harford JB.

PLoS Med. 2014 Sep 9;11(9):e1001721. doi: 10.1371/journal.pmed.1001721. eCollection 2014 Sep. Review. No abstract available.


A comparison of criteria to identify inflammatory breast cancer cases from medical records and the Surveillance, Epidemiology and End Results data base, 2007-2009.

Hirko KA, Soliman AS, Banerjee M, Ruterbusch J, Harford JB, Merajver SD, Schwartz K.

Breast J. 2014 Mar-Apr;20(2):185-91. doi: 10.1111/tbj.12234. Epub 2013 Dec 26.


Trends in Breast Cancer Incidence Rates by Age and Stage at Diagnosis in Gharbiah, Egypt, over 10 Years (1999-2008).

Hirko KA, Soliman AS, Hablas A, Seifeldin IA, Ramadan M, Banerjee M, Harford JB, Chamberlain RM, Merajver SD.

J Cancer Epidemiol. 2013;2013:916394. doi: 10.1155/2013/916394. Epub 2013 Oct 24.


Perspectives on breast cancer in Arab populations.

Corbex M, Harford JB.

Lancet Oncol. 2013 Dec;14(13):e582. doi: 10.1016/S1470-2045(13)70503-5. No abstract available.


Supportive and palliative care for metastatic breast cancer: resource allocations in low- and middle-income countries. A Breast Health Global Initiative 2013 consensus statement.

Cleary J, Ddungu H, Distelhorst SR, Ripamonti C, Rodin GM, Bushnaq MA, Clegg-Lamptey JN, Connor SR, Diwani MB, Eniu A, Harford JB, Kumar S, Rajagopal MR, Thompson B, Gralow JR, Anderson BO.

Breast. 2013 Oct;22(5):616-27. doi: 10.1016/j.breast.2013.07.052. Epub 2013 Aug 21. Review.


Characterizing inflammatory breast cancer among Arab Americans in the California, Detroit and New Jersey Surveillance, Epidemiology and End Results (SEER) registries (1988-2008).

Hirko KA, Soliman AS, Banerjee M, Ruterbusch J, Harford JB, Chamberlain RM, Graff JJ, Merajver SD, Schwartz K.

Springerplus. 2013 Dec;2(1):3. doi: 10.1186/2193-1801-2-3. Epub 2013 Jan 7.


Evaluation of the impact of NCI's Summer Curriculum on Cancer Prevention on participants from low- and middle-income countries.

Williams MJ, Otero IV, Harford JB.

J Cancer Educ. 2013 Mar;28(1):27-32. doi: 10.1007/s13187-013-0455-3.


The need for more and better palliative care for Muslim patients.

Harford JB, Aljawi DM.

Palliat Support Care. 2013 Feb;11(1):1-4. doi: 10.1017/S1478951512000053. Epub 2012 Jul 6. No abstract available.


Approaches for the Evaluation of the National Cancer Institute's Summer Curriculum in Cancer Prevention: lessons from the all-Ireland NCI cancer consortium.

Otero IV, Williams M, Harford JB.

J Cancer Educ. 2012 Jun;27(3):450-5. doi: 10.1007/s13187-012-0368-6.


Viral infections and human cancers: the legacy of Denis Burkitt.

Harford JB.

Br J Haematol. 2012 Mar;156(6):709-18. doi: 10.1111/j.1365-2141.2011.09017.x. Epub 2012 Jan 11. Review.


Association of inflammatory and noninflammatory breast cancer with socioeconomic characteristics in the Surveillance, Epidemiology, and End Results database, 2000-2007.

Schlichting JA, Soliman AS, Schairer C, Banerjee M, Rozek LS, Schottenfeld D, Harford JB, Merajver SD.

Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):155-65. doi: 10.1158/1055-9965.EPI-11-0833. Epub 2011 Oct 25.


Optimisation of breast cancer management in low-resource and middle-resource countries: executive summary of the Breast Health Global Initiative consensus, 2010.

Anderson BO, Cazap E, El Saghir NS, Yip CH, Khaled HM, Otero IV, Adebamowo CA, Badwe RA, Harford JB.

Lancet Oncol. 2011 Apr;12(4):387-98. doi: 10.1016/S1470-2045(11)70031-6.


Breast cancer management in middle-resource countries (MRCs): consensus statement from the Breast Health Global Initiative.

Yip CH, Cazap E, Anderson BO, Bright KL, Caleffi M, Cardoso F, Elzawawy AM, Harford JB, Krygier GD, Masood S, Murillo R, Muse IM, Otero IV, Passman LJ, Santini LA, da Silva RC, Thomas DB, Torres S, Zheng Y, Khaled HM.

Breast. 2011 Apr;20 Suppl 2:S12-9. doi: 10.1016/j.breast.2011.02.015.


Problem solving for breast health care delivery in low and middle resource countries (LMCs): consensus statement from the Breast Health Global Initiative.

Harford JB, Otero IV, Anderson BO, Cazap E, Gradishar WJ, Gralow JR, Kane GM, Niëns LM, Porter PL, Reeler AV, Rieger PT, Shockney LD, Shulman LN, Soldak T, Thomas DB, Thompson B, Winchester DP, Zelle SG, Badwe RA.

Breast. 2011 Apr;20 Suppl 2:S20-9. doi: 10.1016/j.breast.2011.02.007. Epub 2011 Mar 4.


Breast-cancer early detection in low-income and middle-income countries: do what you can versus one size fits all.

Harford JB.

Lancet Oncol. 2011 Mar;12(3):306-12. doi: 10.1016/S1470-2045(10)70273-4.


Cancer control-planning and monitoring population-based systems.

Harford JB, Edwards BK, Nandakumar A, Ndom P, Capocaccia R, Coleman MP; ICCC-3 Session A Group.

Tumori. 2009 Sep-Oct;95(5):568-78.


High proportion of inflammatory breast cancer in the Population-based Cancer Registry of Gharbiah, Egypt.

Soliman AS, Banerjee M, Lo AC, Ismail K, Hablas A, Seifeldin IA, Ramadan M, Omar HG, Fokuda A, Harford JB, Merajver SD.

Breast J. 2009 Jul-Aug;15(4):432-4. doi: 10.1111/j.1524-4741.2009.00755.x. No abstract available.


New ways of initiating translation in eukaryotes.

Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donzé O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M Jr, Gehrke L, Goldman E, Groner Y, Harford JB, Hatzglou M, He B, Hellen CU, Hentze MW, Hershey J, Hershey P, Hohn T, Holcik M, Hunter CP, Igarashi K, Jackson R, Jagus R, Jefferson LS, Joshi B, Kaempfer R, Katze M, Kaufman RJ, Kiledjian M, Kimball SR, Kimchi A, Kirkegaard K, Koromilas AE, Krug RM, Kruys V, Lamphear BJ, Lemon S, Lloyd RE, Maquat LE, Martinez-Salas E, Mathews MB, Mauro VP, Miyamoto S, Mohr I, Morris DR, Moss EG, Nakashima N, Palmenberg A, Parkin NT, Pe'ery T, Pelletier J, Peltz S, Pestova TV, Pilipenko EV, Prats AC, Racaniello V, Read GS, Rhoads RE, Richter JD, Rivera-Pomar R, Rouault T, Sachs A, Sarnow P, Scheper GC, Schiff L, Schoenberg DR, Semler BL, Siddiqui A, Skern T, Sonenberg N, Sossin W, Standart N, Tahara SM, Thomas AA, Toulmé JJ, Wilusz J, Wimmer E, Witherell G, Wormington M.

Mol Cell Biol. 2001 Dec;21(23):8238-46. No abstract available.


Translation-targeted therapeutics for viral diseases.

Harford JB.

Gene Expr. 1995;4(6):357-67. Review.


Cellular iron homeostasis: a paradigm for mechanisms of posttranscriptional control of gene expression.

Harford JB.

Prog Liver Dis. 1994;12:47-62. Review. No abstract available.


Regulating the fate of mRNA: the control of cellular iron metabolism.

Klausner RD, Rouault TA, Harford JB.

Cell. 1993 Jan 15;72(1):19-28. Review. No abstract available.


Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

Haile DJ, Rouault TA, Harford JB, Kennedy MC, Blondin GA, Beinert H, Klausner RD.

Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):11735-9.


Iron regulates the activity of the iron-responsive element binding protein without changing its rate of synthesis or degradation.

Tang CK, Chin J, Harford JB, Klausner RD, Rouault TA.

J Biol Chem. 1992 Dec 5;267(34):24466-70.


Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster.

Haile DJ, Rouault TA, Tang CK, Chin J, Harford JB, Klausner RD.

Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7536-40.


A general method for the detection and quantitation of antigens in solubilized cells using radiolabeled Fab fragment.

Harford JB.

Anal Biochem. 1992 Aug 1;204(2):409-11. No abstract available.


An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein.

Rouault TA, Haile DJ, Downey WE, Philpott CC, Tang C, Samaniego F, Chin J, Paul I, Orloff D, Harford JB, et al.

Biometals. 1992 Autumn;5(3):131-40. Review.


A regulated RNA binding protein also possesses aconitase activity.

Kaptain S, Downey WE, Tang C, Philpott C, Haile D, Orloff DG, Harford JB, Rouault TA, Klausner RD.

Proc Natl Acad Sci U S A. 1991 Nov 15;88(22):10109-13.


Translation and the stability of mRNAs encoding the transferrin receptor and c-fos.

Koeller DM, Horowitz JA, Casey JL, Klausner RD, Harford JB.

Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7778-82.


Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: functional implications.

Rouault TA, Stout CD, Kaptain S, Harford JB, Klausner RD.

Cell. 1991 Mar 8;64(5):881-3. No abstract available.


Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein.

Rouault TA, Tang CK, Kaptain S, Burgess WH, Haile DJ, Samaniego F, McBride OW, Harford JB, Klausner RD.

Proc Natl Acad Sci U S A. 1990 Oct;87(20):7958-62.


The inhibition of the iron responsive element RNA-protein interaction by heme does not mimic in vivo iron regulation.

Haile DJ, Rouault TA, Harford JB, Klausner RD.

J Biol Chem. 1990 Aug 5;265(22):12786-9.


cis-trans models for post-transcriptional gene regulation.

Klausner RD, Harford JB.

Science. 1989 Nov 17;246(4932):870-2. Review. No abstract available.


Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements.

Haile DJ, Hentze MW, Rouault TA, Harford JB, Klausner RD.

Mol Cell Biol. 1989 Nov;9(11):5055-61.


Chromosomal localization of nucleic acid-binding proteins by affinity mapping: assignment of the IRE-binding protein gene to human chromosome 9.

Hentze MW, Seuanez HN, O'Brien SJ, Harford JB, Klausner RD.

Nucleic Acids Res. 1989 Aug 11;17(15):6103-8.


The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein.

Rouault TA, Hentze MW, Haile DJ, Harford JB, Klausner RD.

Proc Natl Acad Sci U S A. 1989 Aug;86(15):5768-72.


A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.

Koeller DM, Casey JL, Hentze MW, Gerhardt EM, Chan LN, Klausner RD, Harford JB.

Proc Natl Acad Sci U S A. 1989 May;86(10):3574-8.

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