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Items: 1 to 50 of 91

1.

Draft Genome of Busseola fusca, the Maize Stalk Borer, a Major Crop Pest in Sub-Saharan Africa.

Hardwick KM, Ojwang' AME, Stomeo F, Maina S, Bichang'a G, Calatayud PA, Filée J, Djikeng A, Miller C, Cepko L, Darby AC, Le Ru B, Schaack S.

Genome Biol Evol. 2019 Aug 1;11(8):2203-2207. doi: 10.1093/gbe/evz166.

2.

The Bub1-TPR Domain Interacts Directly with Mad3 to Generate Robust Spindle Checkpoint Arrest.

Leontiou I, London N, May KM, Ma Y, Grzesiak L, Medina-Pritchard B, Amin P, Jeyaprakash AA, Biggins S, Hardwick KG.

Curr Biol. 2019 Jul 22;29(14):2407-2414.e7. doi: 10.1016/j.cub.2019.06.011. Epub 2019 Jun 27.

3.

Conservation of the Threatened Species, Pulsatilla vulgaris Mill. (Pasqueflower), is Aided by Reproductive System and Polyploidy.

Gargiulo R, Worswick G, Arnold C, Pike LJ, Cowan RS, Hardwick KA, Chapman T, Fay MF.

J Hered. 2019 Aug 16;110(5):618-628. doi: 10.1093/jhered/esz035.

PMID:
31102445
4.

The choice of tree prior and molecular clock does not substantially affect phylogenetic inferences of diversification rates.

Sarver BAJ, Pennell MW, Brown JW, Keeble S, Hardwick KM, Sullivan J, Harmon LJ.

PeerJ. 2019 Mar 13;7:e6334. doi: 10.7717/peerj.6334. eCollection 2019.

5.

Regulated reconstitution of spindle checkpoint arrest and silencing through chemically induced dimerisation in vivo.

Amin P, Soper Ní Chafraidh S, Leontiou I, Hardwick KG.

J Cell Sci. 2018 Oct 4;132(4). pii: jcs219766. doi: 10.1242/jcs.219766.

6.

Neurogaming Technology Meets Neuroscience Education: A Cost-Effective, Scalable, and Highly Portable Undergraduate Teaching Laboratory for Neuroscience.

de Wit B, Badcock NA, Grootswagers T, Hardwick K, Teichmann L, Wehrman J, Williams M, Kaplan DM.

J Undergrad Neurosci Educ. 2017 Jun 15;15(2):A104-A109. eCollection 2017 Spring.

7.

Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest.

May KM, Paldi F, Hardwick KG.

Curr Biol. 2017 Apr 24;27(8):1221-1228. doi: 10.1016/j.cub.2017.03.013. Epub 2017 Mar 30.

8.

Neurochemistry of neurons in the ventrolateral medulla activated by hypotension: Are the same neurons activated by glucoprivation?

Parker LM, Le S, Wearne TA, Hardwick K, Kumar NN, Robinson KJ, McMullan S, Goodchild AK.

J Comp Neurol. 2017 Jun 15;525(9):2249-2264. doi: 10.1002/cne.24203. Epub 2017 Mar 29.

PMID:
28295336
9.

Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast.

Meadows JC, Lancaster TC, Buttrick GJ, Sochaj AM, Messin LJ, Del Mar Mora-Santos M, Hardwick KG, Millar JBA.

Cell Rep. 2017 Feb 7;18(6):1422-1433. doi: 10.1016/j.celrep.2017.01.032.

10.

Generation of a Spindle Checkpoint Arrest from Synthetic Signaling Assemblies.

Yuan I, Leontiou I, Amin P, May KM, Soper Ní Chafraidh S, Zlámalová E, Hardwick KG.

Curr Biol. 2017 Jan 9;27(1):137-143. doi: 10.1016/j.cub.2016.11.014. Epub 2016 Dec 22.

11.

Correction: Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests.

Zich J, May K, Paraskevopoulos K, Sen O, Syred HM, van der Sar S, Patel H, Moresco JJ, Sarkeshik A, Yates JR 3rd, Rappsilber J, Hardwick KG.

PLoS Genet. 2016 Apr 21;12(4):e1006009. doi: 10.1371/journal.pgen.1006009. eCollection 2016 Apr. No abstract available.

12.

Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests.

Zich J, May K, Paraskevopoulos K, Sen O, Syred HM, van der Sar S, Patel H, Moresco JJ, Sarkeshik A, Yates JR 3rd, Rappsilber J, Hardwick KG.

PLoS Genet. 2016 Feb 16;12(2):e1005834. doi: 10.1371/journal.pgen.1005834. eCollection 2016 Feb. Erratum in: PLoS Genet. 2016 Apr;12(4):e1006009.

13.

The population genomics of rapid adaptation: disentangling signatures of selection and demography in white sands lizards.

Laurent S, Pfeifer SP, Settles ML, Hunter SS, Hardwick KM, Ormond L, Sousa VC, Jensen JD, Rosenblum EB.

Mol Ecol. 2016 Jan;25(1):306-23. doi: 10.1111/mec.13385. Epub 2015 Oct 30.

PMID:
26363411
14.

When field experiments yield unexpected results: lessons learned from measuring selection in White Sands lizards.

Hardwick KM, Harmon LJ, Hardwick SD, Rosenblum EB.

PLoS One. 2015 Feb 25;10(2):e0118560. doi: 10.1371/journal.pone.0118560. eCollection 2015.

15.

The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast.

Folco HD, Campbell CS, May KM, Espinoza CA, Oegema K, Hardwick KG, Grewal SIS, Desai A.

Curr Biol. 2015 Feb 2;25(3):348-356. doi: 10.1016/j.cub.2014.11.060. Epub 2015 Jan 22.

16.

Dss1 is a 26S proteasome ubiquitin receptor.

Paraskevopoulos K, Kriegenburg F, Tatham MH, Rösner HI, Medina B, Larsen IB, Brandstrup R, Hardwick KG, Hay RT, Kragelund BB, Hartmann-Petersen R, Gordon C.

Mol Cell. 2014 Nov 6;56(3):453-61. doi: 10.1016/j.molcel.2014.09.008. Epub 2014 Oct 9.

17.

CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation.

Vanoosthuyse V, Legros P, van der Sar SJ, Yvert G, Toda K, Le Bihan T, Watanabe Y, Hardwick K, Bernard P.

PLoS Genet. 2014 Jun 19;10(6):e1004415. doi: 10.1371/journal.pgen.1004415. eCollection 2014 Jun.

18.

Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function.

Kim HS, Mukhopadhyay R, Rothbart SB, Silva AC, Vanoosthuyse V, Radovani E, Kislinger T, Roguev A, Ryan CJ, Xu J, Jahari H, Hardwick KG, Greenblatt JF, Krogan NJ, Fillingham JS, Strahl BD, Bouhassira EE, Edelmann W, Keogh MC.

Cell Rep. 2014 Mar 13;6(5):892-905. doi: 10.1016/j.celrep.2014.01.029. Epub 2014 Feb 22.

19.

Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1.

Patel H, Zich J, Serrels B, Rickman C, Hardwick KG, Frame MC, Brunton VG.

Nat Commun. 2013;4:2056. doi: 10.1038/ncomms3056.

PMID:
23804033
20.

Goldilocks Meets Santa Rosalia: An Ephemeral Speciation Model Explains Patterns of Diversification Across Time Scales.

Rosenblum EB, Sarver BA, Brown JW, Des Roches S, Hardwick KM, Hether TD, Eastman JM, Pennell MW, Harmon LJ.

Evol Biol. 2012 Jun;39(2):255-261. Epub 2012 Mar 14.

21.

Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint.

Shepperd LA, Meadows JC, Sochaj AM, Lancaster TC, Zou J, Buttrick GJ, Rappsilber J, Hardwick KG, Millar JB.

Curr Biol. 2012 May 22;22(10):891-9. doi: 10.1016/j.cub.2012.03.051. Epub 2012 Apr 19.

22.

Evaluation of portable single-gas monitors for the detection of low levels of hydrogen sulfide and sulfur dioxide in petroleum industry environments.

Hemingway MA, Walsh PT, Hardwick KR, Wilcox G.

J Occup Environ Hyg. 2012;9(5):319-28. doi: 10.1080/15459624.2012.670794.

PMID:
22500974
23.

Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex.

Zich J, Sochaj AM, Syred HM, Milne L, Cook AG, Ohkura H, Rappsilber J, Hardwick KG.

Curr Biol. 2012 Feb 21;22(4):296-301. doi: 10.1016/j.cub.2011.12.049. Epub 2012 Jan 25.

24.

Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B.

Buttrick GJ, Meadows JC, Lancaster TC, Vanoosthuyse V, Shepperd LA, Hoe KL, Kim DU, Park HO, Hardwick KG, Millar JB.

Mol Biol Cell. 2011 Dec;22(23):4486-502. doi: 10.1091/mbc.E11-07-0608. Epub 2011 Sep 30.

25.

Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors.

Meadows JC, Shepperd LA, Vanoosthuyse V, Lancaster TC, Sochaj AM, Buttrick GJ, Hardwick KG, Millar JB.

Dev Cell. 2011 Jun 14;20(6):739-50. doi: 10.1016/j.devcel.2011.05.008.

26.

The role of botanic gardens in the science and practice of ecological restoration.

Hardwick KA, Fiedler P, Lee LC, Pavlik B, Hobbs RJ, Aronson J, Bidartondo M, Black E, Coates D, Daws MI, Dixon K, Elliott S, Ewing K, Gann G, Gibbons D, Gratzfeld J, Hamilton M, Hardman D, Harris J, Holmes PM, Jones M, Mabberley D, Mackenzie A, Magdalena C, Marrs R, Milliken W, Mills A, Lughadha EN, Ramsay M, Smith P, Taylor N, Trivedi C, Way M, Whaley O, Hopper SD.

Conserv Biol. 2011 Apr;25(2):265-75. doi: 10.1111/j.1523-1739.2010.01632.x. Epub 2011 Feb 10.

PMID:
21309850
27.

Spindle checkpoint silencing: ensuring rapid and concerted anaphase onset.

Hardwick KG, Shah JV.

F1000 Biol Rep. 2010 Jul 22;2:55. doi: 10.3410/B2-55.

28.

Overcoming inhibition in the spindle checkpoint.

Vanoosthuyse V, Hardwick KG.

Genes Dev. 2009 Dec 15;23(24):2799-805. doi: 10.1101/gad.1882109. Review.

29.

An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe.

Kim HS, Vanoosthuyse V, Fillingham J, Roguev A, Watt S, Kislinger T, Treyer A, Carpenter LR, Bennett CS, Emili A, Greenblatt JF, Hardwick KG, Krogan NJ, Bähler J, Keogh MC.

Nat Struct Mol Biol. 2009 Dec;16(12):1286-93. doi: 10.1038/nsmb.1688. Epub 2009 Nov 15.

30.

Bub3p facilitates spindle checkpoint silencing in fission yeast.

Vanoosthuyse V, Meadows JC, van der Sar SJ, Millar JB, Hardwick KG.

Mol Biol Cell. 2009 Dec;20(24):5096-105. doi: 10.1091/mbc.E09-09-0762.

31.

Getting down to the phosphorylated 'nuts and bolts' of spindle checkpoint signalling.

Zich J, Hardwick KG.

Trends Biochem Sci. 2010 Jan;35(1):18-27. doi: 10.1016/j.tibs.2009.09.002. Epub 2009 Oct 15. Review.

PMID:
19836959
32.

A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism.

Vanoosthuyse V, Hardwick KG.

Curr Biol. 2009 Jul 28;19(14):1176-81. doi: 10.1016/j.cub.2009.05.060. Epub 2009 Jul 9.

33.

The spindle checkpoint: assays for the analysis of spindle checkpoint arrest and recovery.

Fernius J, Hardwick KG.

Methods Mol Biol. 2009;545:243-58. doi: 10.1007/978-1-60327-993-2_15.

PMID:
19475393
34.

Volunteering for the long-term good.

Hardwick KS.

Compend Contin Educ Dent. 2009 Apr;30(3):126, 128. No abstract available.

PMID:
19397067
35.

The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

Sczaniecka M, Feoktistova A, May KM, Chen JS, Blyth J, Gould KL, Hardwick KG.

J Biol Chem. 2008 Aug 22;283(34):23039-47. doi: 10.1074/jbc.M803594200. Epub 2008 Jun 13.

36.

Evidence-based care and the curriculum.

Winning T, Needleman I, Rohlin M, Carrassi A, Chadwick B, Eaton K, Hardwick K, Ivancakova R, Jallaludin RL, Johnsen D, Kim JG, Lekkas D, Li D, Onisei D, Pissiotis A, Reynolds P, Tonni I, Vanobbergen J, Vassileva R, Virtanen J, Wesselink P, Wilson N.

Eur J Dent Educ. 2008 Feb;12 Suppl 1:48-63. doi: 10.1111/j.1600-0579.2007.00480.x. Review.

PMID:
18289268
37.

The spindle checkpoint: how do cells delay anaphase onset?

Sczaniecka MM, Hardwick KG.

SEB Exp Biol Ser. 2008;59:243-56. Review.

PMID:
18368927
39.

Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis.

Fernius J, Hardwick KG.

PLoS Genet. 2007 Nov;3(11):e213. Epub 2007 Oct 15.

40.

Comment on "A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint".

Taylor SS, Hardwick KG, Sawin KE, Biggins S, Piatti S, Khodjakov A, Rieder CL, Salmon ED, Musacchio A.

Science. 2007 May 18;316(5827):982; author reply 982.

41.

Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores.

King EM, Rachidi N, Morrice N, Hardwick KG, Stark MJ.

Genes Dev. 2007 May 15;21(10):1163-8.

42.
43.

Novel sfi1 alleles uncover additional functions for Sfi1p in bipolar spindle assembly and function.

Anderson VE, Prudden J, Prochnik S, Giddings TH Jr, Hardwick KG.

Mol Biol Cell. 2007 Jun;18(6):2047-56. Epub 2007 Mar 28.

44.

Shugoshin 2 regulates localization of the chromosomal passenger proteins in fission yeast mitosis.

Vanoosthuyse V, Prykhozhij S, Hardwick KG.

Mol Biol Cell. 2007 May;18(5):1657-69. Epub 2007 Feb 14.

45.

The spindle checkpoint.

May KM, Hardwick KG.

J Cell Sci. 2006 Oct 15;119(Pt 20):4139-42. Review. No abstract available.

46.

Research education and training in otolaryngology: meeting summary and research opportunities.

Grandis JR, Battey JF, Califf RM, Chole RA, Gantz BJ, Gates GA, Gorelic L, Hannley MT, Hardwick KS, Harris JP, Kapoor WN, Lai SY, Lalwani AK, Minor LB, Nadol JP, Post JC, Roland PS, Schechter AM, Schuller DE, Sklare DA, Wackym PA, Weber RS, Weymuller EA Jr, Wolf GT, Woodson GE.

Otolaryngol Head Neck Surg. 2006 Sep;135(3):361-7. No abstract available.

PMID:
16949965
47.

Control of Shugoshin function during fission-yeast meiosis.

Vaur S, Cubizolles F, Plane G, Genier S, Rabitsch PK, Gregan J, Nasmyth K, Vanoosthuyse V, Hardwick KG, Javerzat JP.

Curr Biol. 2005 Dec 20;15(24):2263-70.

48.

Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis.

Vanoosthuyse V, Hardwick KG.

Trends Cell Biol. 2005 May;15(5):231-3. Review.

PMID:
15866025
49.

Measuring the fate of plant diversity: towards a foundation for future monitoring and opportunities for urgent action.

Nic Lughadha E, Baillie J, Barthlott W, Brummitt NA, Cheek MR, Farjon A, Govaerts R, Hardwick KA, Hilton-Taylor C, Meagher TR, Moat J, Mutke J, Paton AJ, Pleasants LJ, Savolainen V, Schatz GE, Smith P, Turner I, Wyse-Jackson P, Crane PR.

Philos Trans R Soc Lond B Biol Sci. 2005 Feb 28;360(1454):359-72.

50.

Checkpoint signalling: Mad2 conformers and signal propagation.

Hardwick KG.

Curr Biol. 2005 Feb 22;15(4):R122-4. Review.

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