Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 201

1.

Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice.

Wotzka SY, Kreuzer M, Maier L, Arnoldini M, Nguyen BD, Brachmann AO, Berthold DL, Zünd M, Hausmann A, Bakkeren E, Hoces D, Gül E, Beutler M, Dolowschiak T, Zimmermann M, Fuhrer T, Moor K, Sauer U, Typas A, Piel J, Diard M, Macpherson AJ, Stecher B, Sunagawa S, Slack E, Hardt WD.

Nat Microbiol. 2019 Dec;4(12):2164-2174. doi: 10.1038/s41564-019-0568-5. Epub 2019 Oct 7.

PMID:
31591555
2.

Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut.

Bakkeren E, Huisman JS, Fattinger SA, Hausmann A, Furter M, Egli A, Slack E, Sellin ME, Bonhoeffer S, Regoes RR, Diard M, Hardt WD.

Nature. 2019 Sep;573(7773):276-280. doi: 10.1038/s41586-019-1521-8. Epub 2019 Sep 4.

PMID:
31485077
3.

Effects of system response delays on elderly humans' cognitive performance in a virtual training scenario.

Wirzberger M, Schmidt R, Georgi M, Hardt W, Brunnett G, Rey GD.

Sci Rep. 2019 Jun 5;9(1):8291. doi: 10.1038/s41598-019-44718-x.

4.

Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract.

Furter M, Sellin ME, Hansson GC, Hardt WD.

Cell Rep. 2019 May 28;27(9):2665-2678.e3. doi: 10.1016/j.celrep.2019.04.106.

5.

Barcoded Consortium Infections Resolve Cell Type-Dependent Salmonella enterica Serovar Typhimurium Entry Mechanisms.

Di Martino ML, Ek V, Hardt WD, Eriksson J, Sellin ME.

MBio. 2019 May 21;10(3). pii: e00603-19. doi: 10.1128/mBio.00603-19.

6.

Enchained growth and cluster dislocation: A possible mechanism for microbiota homeostasis.

Bansept F, Schumann-Moor K, Diard M, Hardt WD, Slack E, Loverdo C.

PLoS Comput Biol. 2019 May 3;15(5):e1006986. doi: 10.1371/journal.pcbi.1006986. eCollection 2019 May.

7.

Publisher Correction: Definitions and guidelines for research on antibiotic persistence.

Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson DI, Brynildsen MP, Bumann D, Camilli A, Collins JJ, Dehio C, Fortune S, Ghigo JM, Hardt WD, Harms A, Heinemann M, Hung DT, Jenal U, Levin BR, Michiels J, Storz G, Tan MW, Tenson T, Van Melderen L, Zinkernagel A.

Nat Rev Microbiol. 2019 Jul;17(7):460. doi: 10.1038/s41579-019-0207-4.

PMID:
31036919
8.

Definitions and guidelines for research on antibiotic persistence.

Balaban NQ, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson DI, Brynildsen MP, Bumann D, Camilli A, Collins JJ, Dehio C, Fortune S, Ghigo JM, Hardt WD, Harms A, Heinemann M, Hung DT, Jenal U, Levin BR, Michiels J, Storz G, Tan MW, Tenson T, Van Melderen L, Zinkernagel A.

Nat Rev Microbiol. 2019 Jul;17(7):441-448. doi: 10.1038/s41579-019-0196-3. Review. Erratum in: Nat Rev Microbiol. 2019 Apr 29;:.

9.

The Interplay between Salmonella enterica Serovar Typhimurium and the Intestinal Mucosa during Oral Infection.

Hausmann A, Hardt WD.

Microbiol Spectr. 2019 Mar;7(2). doi: 10.1128/microbiolspec.BAI-0004-2019.

PMID:
30953432
10.

Multi-omic measurements of heterogeneity in HeLa cells across laboratories.

Liu Y, Mi Y, Mueller T, Kreibich S, Williams EG, Van Drogen A, Borel C, Frank M, Germain PL, Bludau I, Mehnert M, Seifert M, Emmenlauer M, Sorg I, Bezrukov F, Bena FS, Zhou H, Dehio C, Testa G, Saez-Rodriguez J, Antonarakis SE, Hardt WD, Aebersold R.

Nat Biotechnol. 2019 Mar;37(3):314-322. doi: 10.1038/s41587-019-0037-y. Epub 2019 Feb 18.

PMID:
30778230
11.

ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens.

Proietti M, Perruzza L, Scribano D, Pellegrini G, D'Antuono R, Strati F, Raffaelli M, Gonzalez SF, Thelen M, Hardt WD, Slack E, Nicoletti M, Grassi F.

Nat Commun. 2019 Jan 16;10(1):250. doi: 10.1038/s41467-018-08156-z.

12.

The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium.

Westermann AJ, Venturini E, Sellin ME, Förstner KU, Hardt WD, Vogel J.

MBio. 2019 Jan 2;10(1). pii: e02504-18. doi: 10.1128/mBio.02504-18.

13.

Microbiota stability in healthy individuals after single-dose lactulose challenge-A randomized controlled study.

Wotzka SY, Kreuzer M, Maier L, Zünd M, Schlumberger M, Nguyen B, Fox M, Pohl D, Heinrich H, Rogler G, Biedermann L, Scharl M, Sunagawa S, Hardt WD, Misselwitz B.

PLoS One. 2018 Oct 25;13(10):e0206214. doi: 10.1371/journal.pone.0206214. eCollection 2018.

14.

Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition.

Daga N, Eicher S, Kannan A, Casanova A, Low SH, Kreibich S, Andritschke D, Emmenlauer M, Jenkins JL, Hardt WD, Greber UF, Dehio C, von Mering C.

Nucleic Acids Res. 2018 Oct 12;46(18):9309-9320. doi: 10.1093/nar/gky798.

15.

Inflammatory bactericidal lectin RegIIIβ: Friend or foe for the host?

Miki T, Okada N, Hardt WD.

Gut Microbes. 2018 Mar 4;9(2):179-187. doi: 10.1080/19490976.2017.1387344. Epub 2017 Oct 17.

16.

Basic Processes in Salmonella-Host Interactions: Within-Host Evolution and the Transmission of the Virulent Genotype.

Diard M, Hardt WD.

Microbiol Spectr. 2017 Sep;5(5). doi: 10.1128/microbiolspec.MTBP-0012-2016. Review.

PMID:
28884670
17.

Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness.

Takizawa H, Fritsch K, Kovtonyuk LV, Saito Y, Yakkala C, Jacobs K, Ahuja AK, Lopes M, Hausmann A, Hardt WD, Gomariz Á, Nombela-Arrieta C, Manz MG.

Cell Stem Cell. 2017 Aug 3;21(2):225-240.e5. doi: 10.1016/j.stem.2017.06.013. Epub 2017 Jul 20.

18.

Evolution of bacterial virulence.

Diard M, Hardt WD.

FEMS Microbiol Rev. 2017 Sep 1;41(5):679-697. doi: 10.1093/femsre/fux023. Review.

PMID:
28531298
19.

Consequences of Epithelial Inflammasome Activation by Bacterial Pathogens.

Sellin ME, Müller AA, Hardt WD.

J Mol Biol. 2018 Jan 19;430(2):193-206. doi: 10.1016/j.jmb.2017.03.031. Epub 2017 Apr 25. Review.

PMID:
28454742
20.

Salmonella Typhimurium Diarrhea Reveals Basic Principles of Enteropathogen Infection and Disease-Promoted DNA Exchange.

Wotzka SY, Nguyen BD, Hardt WD.

Cell Host Microbe. 2017 Apr 12;21(4):443-454. doi: 10.1016/j.chom.2017.03.009. Review.

21.

High-avidity IgA protects the intestine by enchaining growing bacteria.

Moor K, Diard M, Sellin ME, Felmy B, Wotzka SY, Toska A, Bakkeren E, Arnoldini M, Bansept F, Co AD, Völler T, Minola A, Fernandez-Rodriguez B, Agatic G, Barbieri S, Piccoli L, Casiraghi C, Corti D, Lanzavecchia A, Regoes RR, Loverdo C, Stocker R, Brumley DR, Hardt WD, Slack E.

Nature. 2017 Apr 27;544(7651):498-502. doi: 10.1038/nature22058. Epub 2017 Apr 12.

PMID:
28405025
22.

Inflammation boosts bacteriophage transfer between Salmonella spp.

Diard M, Bakkeren E, Cornuault JK, Moor K, Hausmann A, Sellin ME, Loverdo C, Aertsen A, Ackermann M, De Paepe M, Slack E, Hardt WD.

Science. 2017 Mar 17;355(6330):1211-1215. doi: 10.1126/science.aaf8451. Epub 2017 Mar 16.

PMID:
28302859
23.

Myeloperoxidase targets oxidative host attacks to Salmonella and prevents collateral tissue damage.

Schürmann N, Forrer P, Casse O, Li J, Felmy B, Burgener AV, Ehrenfeuchter N, Hardt WD, Recher M, Hess C, Tschan-Plessl A, Khanna N, Bumann D.

Nat Microbiol. 2017 Jan 23;2:16268. doi: 10.1038/nmicrobiol.2016.268.

PMID:
28112722
24.

The Bactericidal Lectin RegIIIβ Prolongs Gut Colonization and Enteropathy in the Streptomycin Mouse Model for Salmonella Diarrhea.

Miki T, Goto R, Fujimoto M, Okada N, Hardt WD.

Cell Host Microbe. 2017 Feb 8;21(2):195-207. doi: 10.1016/j.chom.2016.12.008. Epub 2017 Jan 19.

25.

A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion.

Andritschke D, Dilling S, Emmenlauer M, Welz T, Schmich F, Misselwitz B, Rämö P, Rottner K, Kerkhoff E, Wada T, Penninger JM, Beerenwinkel N, Horvath P, Dehio C, Hardt WD.

PLoS One. 2016 Sep 14;11(9):e0161965. doi: 10.1371/journal.pone.0161965. eCollection 2016.

26.

Antimicrobial resistance: Survival by reversible resistance.

Hardt WD.

Nat Microbiol. 2016 May 26;1(6):16072. doi: 10.1038/nmicrobiol.2016.72. No abstract available.

PMID:
27572844
27.

The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium.

Colgan AM, Kröger C, Diard M, Hardt WD, Puente JL, Sivasankaran SK, Hokamp K, Hinton JC.

PLoS Genet. 2016 Aug 26;12(8):e1006258. doi: 10.1371/journal.pgen.1006258. eCollection 2016 Aug.

28.

IFN-γ Hinders Recovery from Mucosal Inflammation during Antibiotic Therapy for Salmonella Gut Infection.

Dolowschiak T, Mueller AA, Pisan LJ, Feigelman R, Felmy B, Sellin ME, Namineni S, Nguyen BD, Wotzka SY, Heikenwalder M, von Mering C, Mueller C, Hardt WD.

Cell Host Microbe. 2016 Aug 10;20(2):238-49. doi: 10.1016/j.chom.2016.06.008. Epub 2016 Jul 21.

29.

An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection.

Müller AA, Dolowschiak T, Sellin ME, Felmy B, Verbree C, Gadient S, Westermann AJ, Vogel J, LeibundGut-Landmann S, Hardt WD.

PLoS Pathog. 2016 Jun 24;12(6):e1005723. doi: 10.1371/journal.ppat.1005723. eCollection 2016 Jun.

30.

Epitope-Tagged Autotransporters as Single-Cell Reporters for Gene Expression by a Salmonella Typhimurium wbaP Mutant.

Curkić I, Schütz M, Oberhettinger P, Diard M, Claassen M, Linke D, Hardt WD.

PLoS One. 2016 May 5;11(5):e0154828. doi: 10.1371/journal.pone.0154828. eCollection 2016.

31.

Autophagy Proteins Promote Repair of Endosomal Membranes Damaged by the Salmonella Type Three Secretion System 1.

Kreibich S, Emmenlauer M, Fredlund J, Rämö P, Münz C, Dehio C, Enninga J, Hardt WD.

Cell Host Microbe. 2015 Nov 11;18(5):527-37. doi: 10.1016/j.chom.2015.10.015.

32.

Antibiotics: Homed to the hideout.

Hardt WD.

Nature. 2015 Nov 19;527(7578):309-10. doi: 10.1038/nature15647. Epub 2015 Nov 4. No abstract available.

PMID:
26536107
33.

Erratum to: gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens.

Schmich F, Szczurek E, Kreibich S, Dilling S, Andritschke D, Casanova A, Low SH, Eicher S, Muntwiler S, Emmenlauer M, Rämo P, Conde-Alvarez R, von Mering C, Hardt WD, Dehio C, Beerenwinkel N.

Genome Biol. 2015 Oct 21;16:233. doi: 10.1186/s13059-015-0807-x. No abstract available.

34.

Population Dynamics Analysis of Ciprofloxacin-Persistent S. Typhimurium Cells in a Mouse Model for Salmonella Diarrhea.

Kaiser P, Regoes RR, Hardt WD.

Methods Mol Biol. 2016;1333:189-203. doi: 10.1007/978-1-4939-2854-5_16.

PMID:
26468110
35.

gespeR: a statistical model for deconvoluting off-target-confounded RNA interference screens.

Schmich F, Szczurek E, Kreibich S, Dilling S, Andritschke D, Casanova A, Low SH, Eicher S, Muntwiler S, Emmenlauer M, Rämö P, Conde-Alvarez R, von Mering C, Hardt WD, Dehio C, Beerenwinkel N.

Genome Biol. 2015 Oct 7;16:220. doi: 10.1186/s13059-015-0783-1. Erratum in: Genome Biol. 2015;16:233.

36.

CD4 T cells are required for both development and maintenance of disease in a new mouse model of reversible colitis.

Brasseit J, Althaus-Steiner E, Faderl M, Dickgreber N, Saurer L, Genitsch V, Dolowschiak T, Li H, Finke D, Hardt WD, McCoy KD, Macpherson AJ, Corazza N, Noti M, Mueller C.

Mucosal Immunol. 2016 May;9(3):689-701. doi: 10.1038/mi.2015.93. Epub 2015 Sep 16.

PMID:
26376366
37.

Correction: Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis.

Maier L, Diard M, Sellin ME, Chouffane ES, Trautwein-Weidner K, Periaswamy B, Slack E, Dolowschiak T, Stecher B, Loverdo C, Regoes RR, Hardt WD.

PLoS Pathog. 2015 Jul 17;11(7):e1005047. doi: 10.1371/journal.ppat.1005047. eCollection 2015 Jul. No abstract available.

38.

Inflammasomes of the intestinal epithelium.

Sellin ME, Maslowski KM, Maloy KJ, Hardt WD.

Trends Immunol. 2015 Aug;36(8):442-50. doi: 10.1016/j.it.2015.06.002. Epub 2015 Jul 9. Review.

PMID:
26166583
39.

Experimental approaches to phenotypic diversity in infection.

Kreibich S, Hardt WD.

Curr Opin Microbiol. 2015 Oct;27:25-36. doi: 10.1016/j.mib.2015.06.007. Epub 2015 Jul 1. Review.

PMID:
26143306
40.

Low-oxygen tensions found in Salmonella-infected gut tissue boost Salmonella replication in macrophages by impairing antimicrobial activity and augmenting Salmonella virulence.

Jennewein J, Matuszak J, Walter S, Felmy B, Gendera K, Schatz V, Nowottny M, Liebsch G, Hensel M, Hardt WD, Gerlach RG, Jantsch J.

Cell Microbiol. 2015 Dec;17(12):1833-47. doi: 10.1111/cmi.12476. Epub 2015 Jul 16.

PMID:
26104016
41.

Indirect Toll-like receptor 5-mediated activation of conventional dendritic cells promotes the mucosal adjuvant activity of flagellin in the respiratory tract.

Fougeron D, Van Maele L, Songhet P, Cayet D, Hot D, Van Rooijen N, Mollenkopf HJ, Hardt WD, Benecke AG, Sirard JC.

Vaccine. 2015 Jun 26;33(29):3331-41. doi: 10.1016/j.vaccine.2015.05.022. Epub 2015 May 21.

PMID:
26003491
42.

Cholera toxin-B (ctxB) antigen expressing Salmonella Typhimurium polyvalent vaccine exerts protective immune response against Vibrio cholerae infection.

Vishwakarma V, Sahoo SS, Das S, Ray S, Hardt WD, Suar M.

Vaccine. 2015 Apr 8;33(15):1880-9. doi: 10.1016/j.vaccine.2015.02.014. Epub 2015 Feb 18.

PMID:
25701672
43.

Simultaneous analysis of large-scale RNAi screens for pathogen entry.

Rämö P, Drewek A, Arrieumerlou C, Beerenwinkel N, Ben-Tekaya H, Cardel B, Casanova A, Conde-Alvarez R, Cossart P, Csúcs G, Eicher S, Emmenlauer M, Greber U, Hardt WD, Helenius A, Kasper C, Kaufmann A, Kreibich S, Kühbacher A, Kunszt P, Low SH, Mercer J, Mudrak D, Muntwiler S, Pelkmans L, Pizarro-Cerdá J, Podvinec M, Pujadas E, Rinn B, Rouilly V, Schmich F, Siebourg-Polster J, Snijder B, Stebler M, Studer G, Szczurek E, Truttmann M, von Mering C, Vonderheit A, Yakimovich A, Bühlmann P, Dehio C.

BMC Genomics. 2014 Dec 22;15:1162. doi: 10.1186/1471-2164-15-1162.

44.

Granulocytes impose a tight bottleneck upon the gut luminal pathogen population during Salmonella typhimurium colitis.

Maier L, Diard M, Sellin ME, Chouffane ES, Trautwein-Weidner K, Periaswamy B, Slack E, Dolowschiak T, Stecher B, Loverdo C, Regoes RR, Hardt WD.

PLoS Pathog. 2014 Dec 18;10(12):e1004557. doi: 10.1371/journal.ppat.1004557. eCollection 2014 Dec. Erratum in: PLoS Pathog. 2015 Jul;11(7):e1005047.

45.

Salmonella Typhimurium strain ATCC14028 requires H2-hydrogenases for growth in the gut, but not at systemic sites.

Maier L, Barthel M, Stecher B, Maier RJ, Gunn JS, Hardt WD.

PLoS One. 2014 Oct 10;9(10):e110187. doi: 10.1371/journal.pone.0110187. eCollection 2014.

46.

Bistable expression of virulence genes in salmonella leads to the formation of an antibiotic-tolerant subpopulation.

Arnoldini M, Vizcarra IA, Peña-Miller R, Stocker N, Diard M, Vogel V, Beardmore RE, Hardt WD, Ackermann M.

PLoS Biol. 2014 Aug 19;12(8):e1001928. doi: 10.1371/journal.pbio.1001928. eCollection 2014 Aug.

47.

Antibiotic treatment selects for cooperative virulence of Salmonella typhimurium.

Diard M, Sellin ME, Dolowschiak T, Arnoldini M, Ackermann M, Hardt WD.

Curr Biol. 2014 Sep 8;24(17):2000-5. doi: 10.1016/j.cub.2014.07.028. Epub 2014 Aug 14.

48.

Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa.

Sellin ME, Müller AA, Felmy B, Dolowschiak T, Diard M, Tardivel A, Maslowski KM, Hardt WD.

Cell Host Microbe. 2014 Aug 13;16(2):237-248. doi: 10.1016/j.chom.2014.07.001.

49.

The Salmonella Typhimurium effector protein SopE transiently localizes to the early SCV and contributes to intracellular replication.

Vonaesch P, Sellin ME, Cardini S, Singh V, Barthel M, Hardt WD.

Cell Microbiol. 2014 Dec;16(12):1723-35. doi: 10.1111/cmi.12333. Epub 2014 Aug 26.

PMID:
25052734
50.

Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens.

Franceschini A, Meier R, Casanova A, Kreibich S, Daga N, Andritschke D, Dilling S, Rämö P, Emmenlauer M, Kaufmann A, Conde-Álvarez R, Low SH, Pelkmans L, Helenius A, Hardt WD, Dehio C, von Mering C.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4548-53. doi: 10.1073/pnas.1402353111. Epub 2014 Mar 10.

Supplemental Content

Support Center