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Items: 1 to 50 of 86

1.

NK cell-intrinsic FcεRIγ limits CD8+ T-cell expansion and thereby turns an acute into a chronic viral infection.

Duhan V, Hamdan TA, Xu HC, Shinde P, Bhat H, Li F, Al-Matary Y, Häussinger D, Bezgovsek J, Friedrich SK, Hardt C, Lang PA, Lang KS.

PLoS Pathog. 2019 Jun 20;15(6):e1007797. doi: 10.1371/journal.ppat.1007797. eCollection 2019 Jun.

2.

Computational Network Analysis for Drug Toxicity Prediction.

Hardt C, Bauer C, Schuchhardt J, Herwig R.

Methods Mol Biol. 2018;1819:335-355. doi: 10.1007/978-1-4939-8618-7_16.

PMID:
30421412
3.

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.

Khairnar V, Duhan V, Patil AM, Zhou F, Bhat H, Thoens C, Sharma P, Adomati T, Friendrich SK, Bezgovsek J, Dreesen JD, Wennemuth G, Westendorf AM, Zelinskyy G, Dittmer U, Hardt C, Timm J, Göthert JR, Lang PA, Singer BB, Lang KS.

Nat Commun. 2018 Jul 2;9(1):2561. doi: 10.1038/s41467-018-04832-2.

4.

Presentation of Autoantigen in Peripheral Lymph Nodes Is Sufficient for Priming Autoreactive CD8+ T Cells.

Honke N, Shaabani N, Teijaro JR, Christen U, Hardt C, Bezgovsek J, Lang PA, Lang KS.

Front Immunol. 2017 Feb 10;8:113. doi: 10.3389/fimmu.2017.00113. eCollection 2017.

5.

Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus Infection.

Honke N, Shaabani N, Hardt C, Krings C, Häussinger D, Lang PA, Lang KS, Keitel V.

Cell Physiol Biochem. 2017;41(1):323-338. doi: 10.1159/000456168. Epub 2017 Jan 25.

6.

CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection.

Shaabani N, Duhan V, Khairnar V, Gassa A, Ferrer-Tur R, Häussinger D, Recher M, Zelinskyy G, Liu J, Dittmer U, Trilling M, Scheu S, Hardt C, Lang PA, Honke N, Lang KS.

Cell Death Dis. 2016 Nov 3;7(11):e2446. doi: 10.1038/cddis.2016.350.

7.

Multiple functions of USP18.

Honke N, Shaabani N, Zhang DE, Hardt C, Lang KS.

Cell Death Dis. 2016 Nov 3;7(11):e2444. doi: 10.1038/cddis.2016.326. Review.

8.

Analyzing and interpreting genome data at the network level with ConsensusPathDB.

Herwig R, Hardt C, Lienhard M, Kamburov A.

Nat Protoc. 2016 Oct;11(10):1889-907. doi: 10.1038/nprot.2016.117. Epub 2016 Sep 8.

PMID:
27606777
9.

ToxDB: pathway-level interpretation of drug-treatment data.

Hardt C, Beber ME, Rasche A, Kamburov A, Hebels DG, Kleinjans JC, Herwig R.

Database (Oxford). 2016 Apr 13;2016. pii: baw052. doi: 10.1093/database/baw052. Print 2016.

10.

High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model.

Gassa A, Kalkavan H, Jian F, Duhan V, Khairnar V, Shaabani N, Honke N, Carpinteiro A, Botezatu L, Crivello P, Dolff S, Ferencik S, Häussinger D, Khandanpour C, Fleischhauer K, Witzke O, Wahlers T, Hardt C, Lang PA, Lang KS.

Cell Physiol Biochem. 2016;38(4):1343-53. doi: 10.1159/000443078. Epub 2016 Mar 24.

11.

IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts.

Gassa A, Jian F, Kalkavan H, Duhan V, Honke N, Shaabani N, Friedrich SK, Dolff S, Wahlers T, Kribben A, Hardt C, Lang PA, Witzke O, Lang KS.

Cell Physiol Biochem. 2016;38(3):1171-81. doi: 10.1159/000443067. Epub 2016 Mar 11.

12.

Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line.

Broecker F, Hardt C, Herwig R, Timmermann B, Kerick M, Wunderlich A, Schweiger MR, Borsig L, Heikenwalder M, Lehrach H, Moelling K.

FEBS J. 2016 May;283(9):1669-88. doi: 10.1111/febs.13694. Epub 2016 Mar 25.

13.

An Impaired Respiratory Electron Chain Triggers Down-regulation of the Energy Metabolism and De-ubiquitination of Solute Carrier Amino Acid Transporters.

Aretz I, Hardt C, Wittig I, Meierhofer D.

Mol Cell Proteomics. 2016 May;15(5):1526-38. doi: 10.1074/mcp.M115.053181. Epub 2016 Feb 6.

14.

Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8(+) T-cell priming and viral control.

Duhan V, Khairnar V, Friedrich SK, Zhou F, Gassa A, Honke N, Shaabani N, Gailus N, Botezatu L, Khandanpour C, Dittmer U, Häussinger D, Recher M, Hardt C, Lang PA, Lang KS.

Sci Rep. 2016 Jan 25;6:19191. doi: 10.1038/srep19191.

15.

Two separate mechanisms of enforced viral replication balance innate and adaptive immune activation.

Shaabani N, Khairnar V, Duhan V, Zhou F, Tur RF, Häussinger D, Recher M, Tumanov AV, Hardt C, Pinschewer D, Christen U, Lang PA, Honke N, Lang KS.

J Autoimmun. 2016 Feb;67:82-89. doi: 10.1016/j.jaut.2015.10.004. Epub 2015 Nov 7.

PMID:
26553386
16.

Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection.

Merches K, Khairnar V, Knuschke T, Shaabani N, Honke N, Duhan V, Recher M, Navarini AA, Hardt C, Häussinger D, Tümmler B, Gulbins E, Futerman AH, Hoffmann D, Lang F, Lang PA, Westendorf AM, Lang KS.

Cell Physiol Biochem. 2015;36(6):2379-92. doi: 10.1159/000430200. Epub 2015 Jul 27.

17.

IFN-γ licenses CD11b(+) cells to induce progression of systemic lupus erythematosus.

Shaabani N, Honke N, Dolff S, Görg B, Khairnar V, Merches K, Duhan V, Metzger S, Recher M, Barthuber C, Hardt C, Proksch P, Häussinger D, Witzke O, Lang PA, Lang KS.

J Autoimmun. 2015 Aug;62:11-21. doi: 10.1016/j.jaut.2015.05.007. Epub 2015 Jun 19.

PMID:
26094774
18.

CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production.

Khairnar V, Duhan V, Maney SK, Honke N, Shaabani N, Pandyra AA, Seifert M, Pozdeev V, Xu HC, Sharma P, Baldin F, Marquardsen F, Merches K, Lang E, Kirschning C, Westendorf AM, Häussinger D, Lang F, Dittmer U, Küppers R, Recher M, Hardt C, Scheffrahn I, Beauchemin N, Göthert JR, Singer BB, Lang PA, Lang KS.

Nat Commun. 2015 Feb 18;6:6217. doi: 10.1038/ncomms7217.

19.

CD49d Treg cells with high suppressive capacity are remarkably less efficient on activated CD45RA- than on naive CD45RA+ Teff cells.

Kraczyk B, Remus R, Hardt C.

Cell Physiol Biochem. 2014;34(2):346-55. doi: 10.1159/000363004. Epub 2014 Jul 9.

20.

Effect of a hyperbolide mastication apparatus for the treatment of severe sleep bruxism in a child with cerebral palsy: long-term follow-up.

Giannasi LC, Freitas Batista SR, Matsui MY, Hardt CT, Gomes CP, Oliveira Amorim JB, Oliveira CS, de Oliveira LV, Gomes MF.

J Bodyw Mov Ther. 2014 Jan;18(1):62-7. doi: 10.1016/j.jbmt.2013.05.009. Epub 2013 Jul 24.

PMID:
24411151
21.

Effects of neuromuscular electrical stimulation, laser therapy and LED therapy on the masticatory system and the impact on sleep variables in cerebral palsy patients: a randomized, five arms clinical trial.

Giannasi LC, Matsui MY, de Freitas Batista SR, Hardt CT, Gomes CP, Amorim JB, de Carvalho Aguiar I, Collange L, Dos Reis Dos Santos I, Dias IS, de Oliveira CS, de Oliveira LV, Gomes MF.

BMC Musculoskelet Disord. 2012 May 15;13:71. doi: 10.1186/1471-2474-13-71.

22.

DIPSBC--data integration platform for systems biology collaborations.

Dreher F, Kreitler T, Hardt C, Kamburov A, Yildirimman R, Schellander K, Lehrach H, Lange BM, Herwig R.

BMC Bioinformatics. 2012 May 8;13:85. doi: 10.1186/1471-2105-13-85.

23.

Co-cultivation of murine BMDCs with 67NR mouse mammary carcinoma cells give rise to highly drug resistant cells.

Nagler C, Hardt C, Zänker KS, Dittmar T.

Cancer Cell Int. 2011 Jun 28;11(1):21. doi: 10.1186/1475-2867-11-21.

24.

Combined sedation with midazolam/propofol for gastrointestinal endoscopy in elderly patients.

Kerker A, Hardt C, Schlief HE, Dumoulin FL.

BMC Gastroenterol. 2010 Jan 27;10:11. doi: 10.1186/1471-230X-10-11.

25.

[Teaching non-technical skills for critical incidents: Crisis resource management training for medical students].

Krüger A, Gillmann B, Hardt C, Döring R, Beckers SK, Rossaint R.

Anaesthesist. 2009 Jun;58(6):582-8. doi: 10.1007/s00101-009-1511-6. German.

PMID:
19189061
27.

Atrial-radiofrequency catheter ablation mediated targeting of mesenchymal stromal cells.

Schweizer PA, Krause U, Becker R, Seckinger A, Bauer A, Hardt C, Eckstein V, Ho AD, Koenen M, Katus HA, Zehelein J.

Stem Cells. 2007 Jun;25(6):1546-51.

28.

CD4+CD25+FoxP3+ T lymphocytes fail to suppress myelin basic protein-induced proliferation in patients with multiple sclerosis.

Kumar M, Putzki N, Limmroth V, Remus R, Lindemann M, Knop D, Mueller N, Hardt C, Kreuzfelder E, Grosse-Wilde H.

J Neuroimmunol. 2006 Nov;180(1-2):178-84. Epub 2006 Sep 29.

PMID:
17011048
29.

Sequence-based typing reveals a novel DLA-88 allele, DLA-88*04501, in a beagle family.

Hardt C, Ferencik S, Tak R, Hoogerbrugge PM, Wagner V, Grosse-Wilde H.

Tissue Antigens. 2006 Feb;67(2):163-5.

PMID:
16441490
30.

Identification of a new HLA-B allele, HLA-B*4443, in a German family.

Thude H, Hardt C, Schorner U, Ferencik S, Helfricht C, Barz D.

Tissue Antigens. 2005 Dec;66(6):696-9.

PMID:
16305687
31.

Multilocus statistics to uncover epistasis and heterogeneity in complex diseases: revisiting a set of multiple sclerosis data.

Böhringer S, Hardt C, Miterski B, Steland A, Epplen JT.

Eur J Hum Genet. 2003 Aug;11(8):573-84.

32.

Helicobacter pylori infection: CagA-specific antibodies are associated with clinical outcome, but not with HLA-class II polymorphisms of the host.

Kunstmann E, Hardt C, Crabtree JE, Suerbaum S, Epplen JT.

Int J Med Microbiol. 2003 Feb;292(7-8):537-40.

PMID:
12635936
33.

[Quality of life in patients with remitting-relapsing multiple sclerosis in Germany].

Haupts M, Elias G, Hardt C, Langenbahn H, Obert H, Pöhlau D, Sczesni B, von Wussow P.

Nervenarzt. 2003 Feb;74(2):144-50. German.

PMID:
12596015
34.

A null mutation in the CNTF gene is not associated with early onset of multiple sclerosis.

Hoffmann V, Hardt C.

Arch Neurol. 2002 Dec;59(12):1974; author reply 1974-5. No abstract available.

PMID:
12470191
35.

Outcome of implant therapy in relation to experienced loss of periodontal bone support: a retrospective 5- year study.

Hardt CR, Gröndahl K, Lekholm U, Wennström JL.

Clin Oral Implants Res. 2002 Oct;13(5):488-94.

PMID:
12453125
36.

Cytokine gene polymorphism in human disease: on-line databases, supplement 2.

Haukim N, Bidwell JL, Smith AJ, Keen LJ, Gallagher G, Kimberly R, Huizinga T, McDermott MF, Oksenberg J, McNicholl J, Pociot F, Hardt C, D'Alfonso S.

Genes Immun. 2002 Sep;3(6):313-30. Review. No abstract available.

37.
38.

In the European population HLA-class II genes are not associated with Helicobacter pylori infection.

Kunstmann E, Hardt C, Treitz H, Suerbaum S, Faller G, Peitz U, Schmiegel W, Epplen JT.

Eur J Gastroenterol Hepatol. 2002 Jan;14(1):49-53.

PMID:
11782575
39.

A complex containing at least one zinc dependent HeLa nuclear protein binds to the intronic (gaa)(n) block of the frataxin gene.

Mäueler W, Bassili G, Hardt C, Keyl HG, Epplen JT.

Gene. 2001 May 30;270(1-2):131-43.

PMID:
11404010
40.

Cytokine gene polymorphism in human disease: on-line databases, supplement 1.

Bidwell J, Keen L, Gallagher G, Kimberly R, Huizinga T, McDermott MF, Oksenberg J, McNicholl J, Pociot F, Hardt C, D'Alfonso S.

Genes Immun. 2001 Apr;2(2):61-70. Review. No abstract available.

41.

Quality of life as a predictor for change in disability in MS.

Haupts MR, Hardt C, Pöhlau D, Sczesni B, Elias W, Langenbahn H, Obert HJ, Wussow PV.

Neurology. 2001 May 8;56(9):1250. No abstract available.

PMID:
11342708
42.

The GAA repeat expansion in intron 1 of the frataxin gene is related to the severity of cardiac manifestation in patients with Friedreich's ataxia.

Bit-Avragim N, Perrot A, Schöls L, Hardt C, Kreuz FR, Zühlke C, Bubel S, Laccone F, Vogel HP, Dietz R, Osterziel KJ.

J Mol Med (Berl). 2001;78(11):626-32.

PMID:
11269509
43.

The interferon gene cluster: a candidate region for MS predisposition? Multiple Sclerosis Study Group.

Miterski B, Jaeckel S, Epplen JT, Pöhlau D, Hardt C.

Genes Immun. 1999 Sep;1(1):37-44.

44.

Cytokine gene polymorphism in human disease: on-line databases.

Bidwell J, Keen L, Gallagher G, Kimberly R, Huizinga T, McDermott MF, Oksenberg J, McNicholl J, Pociot F, Hardt C, D'Alfonso S.

Genes Immun. 1999 Sep;1(1):3-19. Review.

45.

Lack of association between the interferon regulatory factor-1 (IRF1) locus at 5q31.1 and multiple sclerosis in Germany, northern Italy, Sardinia and Sweden.

Vandenbroeck K, Hardt C, Louage J, Fiten P, Jäckel S, Ronsse I, Epplen JT, Grimaldi LM, Olsson T, Marrosu MG, Billiau A, Opdenakker G.

Genes Immun. 2000;1(4):290-2.

46.

Interferon gamma gene in rheumatoid arthritis.

Vandenbroeck K, Goris A, Billiau A, Opdenakker G, Hardt C.

Lancet. 2000 Dec 23-30;356(9248):2191-2. No abstract available.

PMID:
11191569
47.

Paternity analysis of alternative male reproductive routes among the langurs (Semnopithecus entellus) of Ramnagar.

Launhardt K, Borries C, Hardt C, Epplen JT, Winkler P.

Anim Behav. 2001 Jan;61(1):53-64.

PMID:
11170696
48.

Oxidative stress in patients with Friedreich ataxia.

Schulz JB, Dehmer T, Schöls L, Mende H, Hardt C, Vorgerd M, Bürk K, Matson W, Dichgans J, Beal MF, Bogdanov MB.

Neurology. 2000 Dec 12;55(11):1719-21.

PMID:
11113228
49.

Genetic analysis of immunomodulating factors in sporadic Parkinson's disease.

Krüger R, Hardt C, Tschentscher F, Jäckel S, Kuhn W, Müller T, Werner J, Woitalla D, Berg D, Kühnl N, Fuchs GA, Santos EJ, Przuntek H, Epplen JT, Schöls L, Riess O.

J Neural Transm (Vienna). 2000;107(5):553-62.

PMID:
11072751
50.

The nonfunctional allele TCRBV6S1B is strongly associated with Helicobacter pylori infection.

Kunstmann E, Hardt C, Elitok E, Harder M, Suerbaum S, Peitz U, Schmiegel W, Epplen JT.

Infect Immun. 2000 Nov;68(11):6493-5.

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