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Items: 1 to 50 of 164

1.

Elevated local senescence in diabetic wound healing is linked to pathological repair via CXCR2.

Wilkinson HN, Clowes C, Banyard KL, Matteuci P, Mace K, Hardman MJ.

J Invest Dermatol. 2019 Jan 23. pii: S0022-202X(19)30021-1. doi: 10.1016/j.jid.2019.01.005. [Epub ahead of print]

PMID:
30684552
2.

Acute phenibut withdrawal: A comprehensive literature review and illustrative case report.

Hardman MI, Sprung J, Weingarten TN.

Bosn J Basic Med Sci. 2018 Dec 3. doi: 10.17305/bjbms.2018.4008. [Epub ahead of print] Review.

3.

A Novel Silver Bioactive Glass Elicits Antimicrobial Efficacy Against Pseudomonas aeruginosa and Staphylococcus aureus in an ex Vivo Skin Wound Biofilm Model.

Wilkinson HN, Iveson S, Catherall P, Hardman MJ.

Front Microbiol. 2018 Jul 3;9:1450. doi: 10.3389/fmicb.2018.01450. eCollection 2018.

4.

Microbial Host Interactions and Impaired Wound Healing in Mice and Humans: Defining a Role for BD14 and NOD2.

Williams H, Campbell L, Crompton RA, Singh G, McHugh BJ, Davidson DJ, McBain AJ, Cruickshank SM, Hardman MJ.

J Invest Dermatol. 2018 Oct;138(10):2264-2274. doi: 10.1016/j.jid.2018.04.014. Epub 2018 Apr 30.

5.

Silver oxysalts promote cutaneous wound healing independent of infection.

Thomason HA, Lovett JM, Spina CJ, Stephenson C, McBain AJ, Hardman MJ.

Wound Repair Regen. 2018 Mar;26(2):144-152. doi: 10.1111/wrr.12627. Epub 2018 Apr 26.

PMID:
29528167
6.

Evaluating STZ-Induced Impaired Wound Healing in Rats.

Ansell DM, Marsh C, Walker L, Hardman MJ, Holden K.

J Invest Dermatol. 2018 Apr;138(4):994-997. doi: 10.1016/j.jid.2017.10.020. Epub 2017 Oct 26. No abstract available.

PMID:
29106932
7.

The role of estrogen in cutaneous ageing and repair.

Wilkinson HN, Hardman MJ.

Maturitas. 2017 Sep;103:60-64. doi: 10.1016/j.maturitas.2017.06.026. Epub 2017 Jun 23. Review.

PMID:
28778334
8.

Cutaneous Nod2 Expression Regulates the Skin Microbiome and Wound Healing in a Murine Model.

Williams H, Crompton RA, Thomason HA, Campbell L, Singh G, McBain AJ, Cruickshank SM, Hardman MJ.

J Invest Dermatol. 2017 Nov;137(11):2427-2436. doi: 10.1016/j.jid.2017.05.029. Epub 2017 Jun 22.

9.

Response to Comment on Crews et al. Role and Determinants of Adherence to Off-loading in Diabetic Foot Ulcer Healing: A Prospective Investigation. Diabetes Care 2016;39:1371-1377.

Crews RT, Shen BJ, Campbell L, Lamont PJ, Hardman M, Boulton AJ, Peyrot M, Kirsner RS, Vileikyte L.

Diabetes Care. 2016 Dec;39(12):e222-e223. No abstract available.

PMID:
27879362
10.

Comparing the Effectiveness of Polymer Debriding Devices Using a Porcine Wound Biofilm Model.

Wilkinson HN, McBain AJ, Stephenson C, Hardman MJ.

Adv Wound Care (New Rochelle). 2016 Nov 1;5(11):475-485.

11.

An ex vivo porcine skin model to evaluate pressure-reducing devices of different mechanical properties used for pressure ulcer prevention.

Yeung CC, Holmes DF, Thomason HA, Stephenson C, Derby B, Hardman MJ.

Wound Repair Regen. 2016 Nov;24(6):1089-1096. doi: 10.1111/wrr.12481. Epub 2016 Oct 18.

PMID:
27717144
12.

Oestrogen promotes healing in a bacterial LPS model of delayed cutaneous wound repair.

Crompton R, Williams H, Ansell D, Campbell L, Holden K, Cruickshank S, Hardman MJ.

Lab Invest. 2016 Apr;96(4):439-49. doi: 10.1038/labinvest.2015.160. Epub 2016 Feb 8.

13.

Ectodysplasin A Pathway Contributes to Human and Murine Skin Repair.

Garcin CL, Huttner KM, Kirby N, Schneider P, Hardman MJ.

J Invest Dermatol. 2016 May;136(5):1022-1030. doi: 10.1016/j.jid.2015.09.002. Epub 2016 Jan 29.

14.

Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialization.

Garcin CL, Ansell DM, Headon DJ, Paus R, Hardman MJ.

Stem Cells. 2016 May;34(5):1377-85. doi: 10.1002/stem.2289. Epub 2016 Feb 2.

15.

Do not be alarmed: understanding IL33-ST2 signalling in wound repair.

Ansell DM, Hardman MJ.

Exp Dermatol. 2016 Jan;25(1):22-3. doi: 10.1111/exd.12887. Epub 2015 Dec 11. No abstract available.

PMID:
26519250
16.

Global Gene Expression Analysis in PKCα-/- Mouse Skin Reveals Structural Changes in the Dermis and Defective Wound Granulation Tissue.

Cooper NH, Balachandra JP, Hardman MJ.

J Invest Dermatol. 2015 Dec;135(12):3173-3182. doi: 10.1038/jid.2015.338. Epub 2015 Sep 9.

17.

Good pharma? Bad pharma? Better pharma.

Hardman M.

J R Coll Physicians Edinb. 2014;44(4):269-72. doi: 10.4997/JRCPE.2014.403. No abstract available.

PMID:
25516893
18.

Estrogen receptor-alpha promotes alternative macrophage activation during cutaneous repair.

Campbell L, Emmerson E, Williams H, Saville CR, Krust A, Chambon P, Mace KA, Hardman MJ.

J Invest Dermatol. 2014 Sep;134(9):2447-2457. doi: 10.1038/jid.2014.175. Epub 2014 Apr 9.

19.

A statistical analysis of murine incisional and excisional acute wound models.

Ansell DM, Campbell L, Thomason HA, Brass A, Hardman MJ.

Wound Repair Regen. 2014 Mar-Apr;22(2):281-7. doi: 10.1111/wrr.12148.

20.

Topical photodynamic therapy following excisional wounding of human skin increases production of transforming growth factor-β3 and matrix metalloproteinases 1 and 9, with associated improvement in dermal matrix organization.

Mills SJ, Farrar MD, Ashcroft GS, Griffiths CE, Hardman MJ, Rhodes LE.

Br J Dermatol. 2014 Jul;171(1):55-62. doi: 10.1111/bjd.12843. Epub 2014 Jun 24.

PMID:
24471979
21.

Course fees and academic ranking: insights from the IMI EMTRAIN on-course® database.

Payton A, Dallakian P, Fitton A, Payton A, Hardman M, Yuille M.

Drug Discov Today. 2014 Jul;19(7):830-3. doi: 10.1016/j.drudis.2013.12.001. Epub 2013 Dec 8. Review.

PMID:
24325828
22.

Novel parallelized quadrupole/linear ion trap/Orbitrap tribrid mass spectrometer improving proteome coverage and peptide identification rates.

Senko MW, Remes PM, Canterbury JD, Mathur R, Song Q, Eliuk SM, Mullen C, Earley L, Hardman M, Blethrow JD, Bui H, Specht A, Lange O, Denisov E, Makarov A, Horning S, Zabrouskov V.

Anal Chem. 2013 Dec 17;85(24):11710-4. doi: 10.1021/ac403115c. Epub 2013 Nov 27.

PMID:
24251866
23.

Diabetes induces stable intrinsic changes to myeloid cells that contribute to chronic inflammation during wound healing in mice.

Bannon P, Wood S, Restivo T, Campbell L, Hardman MJ, Mace KA.

Dis Model Mech. 2013 Nov;6(6):1434-47. doi: 10.1242/dmm.012237. Epub 2013 Sep 18.

24.

Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin.

Meier NT, Haslam IS, Pattwell DM, Zhang GY, Emelianov V, Paredes R, Debus S, Augustin M, Funk W, Amaya E, Kloepper JE, Hardman MJ, Paus R.

PLoS One. 2013 Sep 2;8(9):e73596. doi: 10.1371/journal.pone.0073596. eCollection 2013.

25.

Estrogen receptor-mediated signalling in female mice is locally activated in response to wounding.

Emmerson E, Rando G, Meda C, Campbell L, Maggi A, Hardman MJ.

Mol Cell Endocrinol. 2013 Aug 15;375(1-2):149-56. doi: 10.1016/j.mce.2013.05.015. Epub 2013 May 29.

PMID:
23727624
26.

on-course(®) portal: a tool for in-service training and career development for biomedical scientists.

Payton A, Janko C, Renn O, Hardman M; EMTRAIN Consortium.

Drug Discov Today. 2013 Sep;18(17-18):803-6. doi: 10.1016/j.drudis.2013.04.004. Epub 2013 Apr 15.

PMID:
23597757
27.

Local arginase 1 activity is required for cutaneous wound healing.

Campbell L, Saville CR, Murray PJ, Cruickshank SM, Hardman MJ.

J Invest Dermatol. 2013 Oct;133(10):2461-2470. doi: 10.1038/jid.2013.164. Epub 2013 Apr 3.

28.

Nod2 deficiency impairs inflammatory and epithelial aspects of the cutaneous wound-healing response.

Campbell L, Williams H, Crompton RA, Cruickshank SM, Hardman MJ.

J Pathol. 2013 Jan;229(1):121-31. doi: 10.1002/path.4095.

PMID:
22951952
29.

Insulin-like growth factor-1 promotes wound healing in estrogen-deprived mice: new insights into cutaneous IGF-1R/ERα cross talk.

Emmerson E, Campbell L, Davies FC, Ross NL, Ashcroft GS, Krust A, Chambon P, Hardman MJ.

J Invest Dermatol. 2012 Dec;132(12):2838-48. doi: 10.1038/jid.2012.228. Epub 2012 Jul 19.

30.

Animal models of wound repair: Are they cutting it?

Ansell DM, Holden KA, Hardman MJ.

Exp Dermatol. 2012 Aug;21(8):581-5. doi: 10.1111/j.1600-0625.2012.01540.x.

31.

Direct evidence that PKCα positively regulates wound re-epithelialization: correlation with changes in desmosomal adhesiveness.

Thomason HA, Cooper NH, Ansell DM, Chiu M, Merrit AJ, Hardman MJ, Garrod DR.

J Pathol. 2012 Jul;227(3):346-56. doi: 10.1002/path.4016. Epub 2012 May 8.

PMID:
22407785
32.

Tumor necrosis factor-alpha (TNF-α) is a therapeutic target for impaired cutaneous wound healing.

Ashcroft GS, Jeong MJ, Ashworth JJ, Hardman M, Jin W, Moutsopoulos N, Wild T, McCartney-Francis N, Sim D, McGrady G, Song XY, Wahl SM.

Wound Repair Regen. 2012 Jan-Feb;20(1):38-49. doi: 10.1111/j.1524-475X.2011.00748.x. Epub 2011 Dec 8.

33.

Group therapy for school-aged children who stutter: a survey of current practices.

Liddle H, James S, Hardman M.

J Fluency Disord. 2011 Dec;36(4):274-9. doi: 10.1016/j.jfludis.2011.02.004. Epub 2011 Mar 1.

PMID:
22133404
34.

Collaborative project to co-ordinate care for patients with dementia.

Kennerley D, Bolas R, Bourne J, Branson K, Cavenagh P, Chappell P, Collins G, Coveney N, Day N, Hardman M, Hayter S, Fenner P, Jones J, Jordan S, Noble B, Osbourne S, Smith C, Wigens L; Suffolk Nurse Leaders Group.

Nurs Manag (Harrow). 2011 May;18(2):27-31.

PMID:
21675487
35.

The role of estrogen deficiency in skin ageing and wound healing.

Emmerson E, Hardman MJ.

Biogerontology. 2012 Feb;13(1):3-20. doi: 10.1007/s10522-011-9322-y. Epub 2011 Mar 3. Review.

PMID:
21369728
36.

MIF: a key player in cutaneous biology and wound healing.

Gilliver SC, Emmerson E, Bernhagen J, Hardman MJ.

Exp Dermatol. 2011 Jan;20(1):1-6. doi: 10.1111/j.1600-0625.2010.01194.x. Review.

PMID:
21158933
37.

Coping and depression in diabetic foot ulcer healing: causal influence, mechanistic evidence or none of the above?

Gonzalez JS, Hardman MJ, Boulton AJ, Vileikyte L.

Diabetologia. 2011 Jan;54(1):205-6. doi: 10.1007/s00125-010-1926-2. Epub 2010 Oct 13. No abstract available.

PMID:
20938635
38.

Exploring the "hair growth-wound healing connection": anagen phase promotes wound re-epithelialization.

Ansell DM, Kloepper JE, Thomason HA, Paus R, Hardman MJ.

J Invest Dermatol. 2011 Feb;131(2):518-28. doi: 10.1038/jid.2010.291. Epub 2010 Oct 7.

39.

Estrogen promotes cutaneous wound healing via estrogen receptor beta independent of its antiinflammatory activities.

Campbell L, Emmerson E, Davies F, Gilliver SC, Krust A, Chambon P, Ashcroft GS, Hardman MJ.

J Exp Med. 2010 Aug 30;207(9):1825-33. doi: 10.1084/jem.20100500. Epub 2010 Aug 23.

40.

17beta-estradiol inhibits wound healing in male mice via estrogen receptor-alpha.

Gilliver SC, Emmerson E, Campbell L, Chambon P, Hardman MJ, Ashcroft GS.

Am J Pathol. 2010 Jun;176(6):2707-21. doi: 10.2353/ajpath.2010.090432. Epub 2010 May 6.

41.

Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice.

Waite A, Gilliver SC, Masterson GR, Hardman MJ, Ashcroft GS.

Br J Anaesth. 2010 Jun;104(6):768-73. doi: 10.1093/bja/aeq093. Epub 2010 Apr 24.

42.

The phytoestrogen genistein promotes wound healing by multiple independent mechanisms.

Emmerson E, Campbell L, Ashcroft GS, Hardman MJ.

Mol Cell Endocrinol. 2010 Jun 10;321(2):184-93. doi: 10.1016/j.mce.2010.02.026. Epub 2010 Mar 1.

PMID:
20193736
43.

The role of sex hormones in the development of Th2 immunity in a gender-biased model of Trichuris muris infection.

Hepworth MR, Hardman MJ, Grencis RK.

Eur J Immunol. 2010 Feb;40(2):406-16. doi: 10.1002/eji.200939589.

44.

Whole-mount assays for gene induction and barrier formation in the developing epidermis.

Byrne C, Avilion AA, O'Shaughnessy RF, Welti JC, Hardman MJ.

Methods Mol Biol. 2010;585:271-86. doi: 10.1007/978-1-60761-380-0_19.

PMID:
19908010
45.

Novel locally active estrogens accelerate cutaneous wound healing. A preliminary study.

Brufani M, Ceccacci F, Filocamo L, Garofalo B, Joudioux R, La Bella A, Leonelli F, Migneco LM, Bettolo RM, Farina PM, Ashcroft GS, Routley C, Hardman M, Meda C, Rando G, Maggi A.

Mol Pharm. 2009 Mar-Apr;6(2):543-56. doi: 10.1021/mp800206b.

PMID:
19718805
46.

Unique and synergistic roles for 17beta-estradiol and macrophage migration inhibitory factor during cutaneous wound closure are cell type specific.

Emmerson E, Campbell L, Ashcroft GS, Hardman MJ.

Endocrinology. 2009 Jun;150(6):2749-57. doi: 10.1210/en.2008-1569. Epub 2009 Feb 5.

PMID:
19196797
47.

5alpha-dihydrotestosterone (DHT) retards wound closure by inhibiting re-epithelialization.

Gilliver SC, Ruckshanthi JP, Hardman MJ, Zeef LA, Ashcroft GS.

J Pathol. 2009 Jan;217(1):73-82. doi: 10.1002/path.2444.

PMID:
18855875
48.

Sex dimorphism in wound healing: the roles of sex steroids and macrophage migration inhibitory factor.

Gilliver SC, Ruckshanthi JP, Hardman MJ, Nakayama T, Ashcroft GS.

Endocrinology. 2008 Nov;149(11):5747-57. doi: 10.1210/en.2008-0355. Epub 2008 Jul 24.

PMID:
18653719
49.

Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly.

Hardman MJ, Ashcroft GS.

Genome Biol. 2008;9(5):R80. doi: 10.1186/gb-2008-9-5-r80. Epub 2008 May 13.

50.

Molecular systematics of the Holarctic Anoplocephaloides variabilis (Douthitt, 1915) complex, with the proposal of Microcephaloides n. g. (Cestoda: Anoplocephalidae).

Haukisalmi V, Hardman LM, Hardman M, Rausch RL, Henttonen H.

Syst Parasitol. 2008 May;70(1):15-26. doi: 10.1007/s11230-008-9129-7. Epub 2008 Mar 29.

PMID:
18373216

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