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Items: 17


Bone, subcutaneous tissue and plasma pharmacokinetics of cefuroxime in total knee replacement patients - a randomized controlled trial comparing continuous and short-term infusion.

Tøttrup M, Søballe K, Bibby BM, Hardlei TF, Hansen P, Fuursted K, Birke-Sørensen H, Bue M.

APMIS. 2019 Dec;127(12):779-788. doi: 10.1111/apm.12996. Epub 2019 Oct 14.


Population Pharmacokinetics of Meropenem in Plasma and Subcutis from Patients on Extracorporeal Membrane Oxygenation Treatment.

Hanberg P, Öbrink-Hansen K, Thorsted A, Bue M, Tøttrup M, Friberg LE, Hardlei TF, Søballe K, Gjedsted J.

Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02390-17. doi: 10.1128/AAC.02390-17. Print 2018 May.


Penicillin G Treatment in Infective Endocarditis Patients - Does Standard Dosing Result in Therapeutic Plasma Concentrations?

Öbrink-Hansen K, Wiggers H, Bibby BM, Hardlei TF, Jensen K, Kragh Thomsen M, Brock B, Petersen E.

Basic Clin Pharmacol Toxicol. 2017 Feb;120(2):179-186. doi: 10.1111/bcpt.12661. Epub 2016 Sep 16.


Artemether-Lumefantrine Concentrations in Tablets and Powders from Ghana Measured by a New High-Performance Liquid Chromatography Method.

Debrah P, Nettey H, Miltersen KK, Ayeh-Kumi P, Brock B, Sarkodie JA, Akwo-Kretchy I, Owusu-Danso P, Adjei S, Petersen E, Hardlei TF.

Am J Trop Med Hyg. 2016 Jul 6;95(1):158-63. doi: 10.4269/ajtmh.15-0868. Epub 2016 May 2.


Piperacillin/tazobactam continuous infusion at 12G/1.5G per day in CF patients results in target plasma-concentrations.

Öbrink-Hansen K, Jensen-Fangel S, Brock B, Hardlei TF, Adelfred A, Nejatbakhsh Y, Kragh Thomsen M, Petersen E.

J Cyst Fibros. 2016 Mar;15(2):e13-4. doi: 10.1016/j.jcf.2015.10.005. Epub 2015 Oct 17. No abstract available.


Population pharmacokinetics of piperacillin in the early phase of septic shock: does standard dosing result in therapeutic plasma concentrations?

Öbrink-Hansen K, Juul RV, Storgaard M, Thomsen MK, Hardlei TF, Brock B, Kreilgaard M, Gjedsted J.

Antimicrob Agents Chemother. 2015 Nov;59(11):7018-26. doi: 10.1128/AAC.01347-15. Epub 2015 Sep 8.


Single-dose pharmacokinetics of vancomycin in porcine cancellous and cortical bone determined by microdialysis.

Bue M, Birke-Sørensen H, Thillemann TM, Hardlei TF, Søballe K, Tøttrup M.

Int J Antimicrob Agents. 2015 Oct;46(4):434-8. doi: 10.1016/j.ijantimicag.2015.06.014. Epub 2015 Jul 28.


Moxifloxacin pharmacokinetic profile and efficacy evaluation in empiric treatment of community-acquired pneumonia.

Öbrink-Hansen K, Hardlei TF, Brock B, Jensen-Fangel S, Kragh Thomsen M, Petersen E, Kreilgaard M.

Antimicrob Agents Chemother. 2015 Apr;59(4):2398-404. doi: 10.1128/AAC.04659-14. Epub 2015 Feb 9.


Continuous versus short-term infusion of cefuroxime: assessment of concept based on plasma, subcutaneous tissue, and bone pharmacokinetics in an animal model.

Tøttrup M, Bibby BM, Hardlei TF, Bue M, Kerrn-Jespersen S, Fuursted K, Søballe K, Birke-Sørensen H.

Antimicrob Agents Chemother. 2015 Jan;59(1):67-75. doi: 10.1128/AAC.03857-14. Epub 2014 Oct 13.


Pharmacokinetics of cefuroxime in porcine cortical and cancellous bone determined by microdialysis.

Tøttrup M, Hardlei TF, Bendtsen M, Bue M, Brock B, Fuursted K, Søballe K, Birke-Sørensen H.

Antimicrob Agents Chemother. 2014 Jun;58(6):3200-5. doi: 10.1128/AAC.02438-14. Epub 2014 Mar 24.


Low-dose acetylsalicylic acid therapy monitored with ultra high performance liquid chromatography.

Rubak P, Hardlei TF, Würtz M, Kristensen SD, Hvas AM.

Clin Biochem. 2013 Aug;46(12):988-992. doi: 10.1016/j.clinbiochem.2013.04.007. Epub 2013 Apr 19.


Cobalamin analogues in humans: a study on maternal and cord blood.

Hardlei TF, Obeid R, Herrmann W, Nexo E.

PLoS One. 2013 Apr 9;8(4):e61194. doi: 10.1371/journal.pone.0061194. Print 2013.


The vitamin B12 absorption test, CobaSorb, identifies patients not requiring vitamin B12 injection therapy.

Hvas AM, Morkbak AL, Hardlei TF, Nexo E.

Scand J Clin Lab Invest. 2011 Sep;71(5):432-8. doi: 10.3109/00365513.2011.581389. Epub 2011 May 30.


Assessment of vitamin B(12) absorption based on the accumulation of orally administered cyanocobalamin on transcobalamin.

Hardlei TF, Mørkbak AL, Bor MV, Bailey LB, Hvas AM, Nexo E.

Clin Chem. 2010 Mar;56(3):432-6. doi: 10.1373/clinchem.2009.131524. Epub 2009 Dec 29.


A new principle for measurement of cobalamin and corrinoids, used for studies of cobalamin analogs on serum haptocorrin.

Hardlei TF, Nexo E.

Clin Chem. 2009 May;55(5):1002-10. doi: 10.1373/clinchem.2008.114132. Epub 2009 Mar 19.


High concentrations of haptocorrin interfere with routine measurement of cobalamins in human serum and milk. A problem and its solution.

Lildballe DL, Hardlei TF, Allen LH, Nexo E.

Clin Chem Lab Med. 2009;47(2):182-7. doi: 10.1515/CCLM.2009.047.


Enzymatic extraction of cobalamin from monoclonal antibody captured haptocorrin and transcobalamin.

Hardlei TF, Morkbak AL, Nexo E.

Clin Biochem. 2007 Dec;40(18):1392-7. Epub 2007 Sep 25.


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