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Items: 21

1.

Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice.

Belmar NA, Chan SW, Fox MI, Samayoa JA, Stickler MM, Tran NN, Akamatsu Y, Hollenbaugh D, Harding FA, Alvarez HM.

J Immunol. 2017 Jun 1;198(11):4502-4512. doi: 10.4049/jimmunol.1601512. Epub 2017 Apr 26.

2.

The human G1m1 allotype associates with CD4+ T-cell responsiveness to a highly conserved IgG1 constant region peptide and confers an asparaginyl endopeptidase cleavage site.

Stickler MM, Reddy A, Xiong JM, Hinton PR, DuBridge R, Harding FA.

Genes Immun. 2011 Apr;12(3):213-21. doi: 10.1038/gene.2010.68. Epub 2011 Feb 17.

3.

The immunogenicity of humanized and fully human antibodies: residual immunogenicity resides in the CDR regions.

Harding FA, Stickler MM, Razo J, DuBridge RB.

MAbs. 2010 May-Jun;2(3):256-65. Epub 2010 May 1.

4.

A beta-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy.

Harding FA, Liu AD, Stickler M, Razo OJ, Chin R, Faravashi N, Viola W, Graycar T, Yeung VP, Aehle W, Meijer D, Wong S, Rashid MH, Valdes AM, Schellenberger V.

Mol Cancer Ther. 2005 Nov;4(11):1791-800.

5.

Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope.

Yeung VP, Chang J, Miller J, Barnett C, Stickler M, Harding FA.

J Immunol. 2004 Jun 1;172(11):6658-65.

6.

The HLA-DR2 haplotype is associated with an increased proliferative response to the immunodominant CD4(+) T-cell epitope in human interferon-beta.

Stickler M, Valdes AM, Gebel W, Razo OJ, Faravashi N, Chin R, Rochanayon N, Harding FA.

Genes Immun. 2004 Jan;5(1):1-7.

PMID:
14735143
7.

An in vitro human cell-based assay to rank the relative immunogenicity of proteins.

Stickler M, Rochanayon N, Razo OJ, Mucha J, Gebel W, Faravashi N, Chin R, Holmes S, Harding FA.

Toxicol Sci. 2004 Feb;77(2):280-9. Epub 2003 Dec 22.

PMID:
14691215
8.

Human population-based identification of CD4(+) T-cell peptide epitope determinants.

Stickler M, Chin R, Faravashi N, Gebel W, Razo OJ, Rochanayon N, Power S, Valdes AM, Holmes S, Harding FA.

J Immunol Methods. 2003 Oct 1;281(1-2):95-108.

PMID:
14580884
9.

Enhanced immunogenicity of a functional enzyme by T cell epitope modification.

Mucha JM, Stickler MM, Poulose AJ, Ganshaw G, Saldajeno M, Collier K, Huang MT, Harding FA.

BMC Immunol. 2002;3:2. Epub 2002 Jan 25.

10.

CD4+ T-cell epitope determination using unexposed human donor peripheral blood mononuclear cells.

Stickler MM, Estell DA, Harding FA.

J Immunother. 2000 Nov-Dec;23(6):654-60.

PMID:
11186153
11.

Class switching in human immunoglobulin transgenic mice.

Harding FA, Lonberg N.

Ann N Y Acad Sci. 1995 Sep 29;764:536-46.

PMID:
7486582
12.

Antigen-specific human antibodies from mice comprising four distinct genetic modifications.

Lonberg N, Taylor LD, Harding FA, Trounstine M, Higgins KM, Schramm SR, Kuo CC, Mashayekh R, Wymore K, McCabe JG, et al.

Nature. 1994 Apr 28;368(6474):856-9.

PMID:
8159246
13.

MHC restriction of T-cell proliferative responses in Xenopus.

Harding FA, Flajnik MF, Cohen N.

Dev Comp Immunol. 1993 Sep-Oct;17(5):425-37.

PMID:
7505753
14.
15.

Immune system activation associated with a naturally occurring infection in Xenopus laevis.

Haynes L, Harding FA, Koniski AD, Cohen N.

Dev Comp Immunol. 1992 Nov-Dec;16(6):453-62.

PMID:
1473595
16.

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones.

Harding FA, McArthur JG, Gross JA, Raulet DH, Allison JP.

Nature. 1992 Apr 16;356(6370):607-9.

PMID:
1313950
17.

Evolutionary development of immunoglobulin gene diversity.

Litman GW, Amemiya CT, Harding FA, Haire RN, Hinds KR, Litman RT, Ohta Y, Shamblott MJ, Varner JA.

Adv Exp Med Biol. 1991;292:11-7. Review. No abstract available.

PMID:
1950762
18.

Two distinct immunoglobulin heavy chain isotypes in a primitive, cartilaginous fish, Raja erinacea.

Harding FA, Amemiya CT, Litman RT, Cohen N, Litman GW.

Nucleic Acids Res. 1990 Nov 11;18(21):6369-76.

19.

Immunoglobulin heavy chain gene organization and complexity in the skate, Raja erinacea.

Harding FA, Cohen N, Litman GW.

Nucleic Acids Res. 1990 Feb 25;18(4):1015-20.

20.

Teratogen metabolism: thalidomide activation is mediated by cytochrome P-450.

Braun AG, Harding FA, Weinreb SL.

Toxicol Appl Pharmacol. 1986 Jan;82(1):175-9.

PMID:
3945939
21.

Should vocational rehabilitation agencies rehabilitate the Negro?

Harding FA.

J Rehabil. 1968 May;34(3):14-5. No abstract available.

PMID:
5653286

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