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Items: 1 to 50 of 69

1.

Longitudinal free-breathing MRI measurement of murine lung physiology in a progressive model of lung fibrosis.

Guo J, Hardie WD, Cleveland ZI, Davidson C, Xu X, Madala SK, Woods JC.

J Appl Physiol (1985). 2019 Apr 1;126(4):1138-1149. doi: 10.1152/japplphysiol.00993.2018. Epub 2019 Feb 7.

PMID:
30730810
2.

Subacute TGFβ expression drives inflammation, goblet cell hyperplasia, and pulmonary function abnormalities in mice with effects dependent on CFTR function.

Kramer EL, Hardie WD, Madala SK, Davidson C, Clancy JP.

Am J Physiol Lung Cell Mol Physiol. 2018 Sep 1;315(3):L456-L465. doi: 10.1152/ajplung.00530.2017. Epub 2018 Jun 7.

PMID:
29877096
3.

Mast cell chymase affects the proliferation and metastasis of lung carcinoma cells in vitro.

Jiang Y, Wu Y, Hardie WJ, Zhou X.

Oncol Lett. 2017 Sep;14(3):3193-3198. doi: 10.3892/ol.2017.6487. Epub 2017 Jun 28.

4.

Bronchopulmonary Dysplasia and Perinatal Characteristics Predict 1-Year Respiratory Outcomes in Newborns Born at Extremely Low Gestational Age: A Prospective Cohort Study.

Keller RL, Feng R, DeMauro SB, Ferkol T, Hardie W, Rogers EE, Stevens TP, Voynow JA, Bellamy SL, Shaw PA, Moore PE; Prematurity and Respiratory Outcomes Program.

J Pediatr. 2017 Aug;187:89-97.e3. doi: 10.1016/j.jpeds.2017.04.026. Epub 2017 May 17.

5.

Magnetic resonance imaging of disease progression and resolution in a transgenic mouse model of pulmonary fibrosis.

Cleveland ZI, Zhou YM, Akinyi TG, Dunn RS, Davidson CR, Guo J, Woods JC, Hardie WD.

Am J Physiol Lung Cell Mol Physiol. 2017 Apr 1;312(4):L488-L499. doi: 10.1152/ajplung.00458.2016. Epub 2017 Jan 27.

6.

Results of a Prospective Study Evaluating a Noninvasive Method of Hemoglobin Adjustment for Determining the Diffusing Capacity of the Lung.

Foster KE, Sahay RD, Zhang N, Hardie WD.

Ann Am Thorac Soc. 2017 Jan;14(1):41-48. doi: 10.1513/AnnalsATS.201603-197OC.

PMID:
27870589
7.

Unique and Redundant Functions of p70 Ribosomal S6 Kinase Isoforms Regulate Mesenchymal Cell Proliferation and Migration in Pulmonary Fibrosis.

Madala SK, Sontake V, Edukulla R, Davidson CR, Schmidt S, Hardie WD.

Am J Respir Cell Mol Biol. 2016 Dec;55(6):792-803.

8.

Mechanisms of Lung Fibrosis Resolution.

Glasser SW, Hagood JS, Wong S, Taype CA, Madala SK, Hardie WD.

Am J Pathol. 2016 May;186(5):1066-77. doi: 10.1016/j.ajpath.2016.01.018. Epub 2016 Mar 25. Review.

9.

Pulmonary Morbidity in Infancy after Exposure to Chorioamnionitis in Late Preterm Infants.

McDowell KM, Jobe AH, Fenchel M, Hardie WD, Gisslen T, Young LR, Chougnet CA, Davis SD, Kallapur SG.

Ann Am Thorac Soc. 2016 Jun;13(6):867-76. doi: 10.1513/AnnalsATS.201507-411OC.

10.

p70 ribosomal S6 kinase regulates subpleural fibrosis following transforming growth factor-α expression in the lung.

Madala SK, Thomas G, Edukulla R, Davidson C, Schmidt S, Schehr A, Hardie WD.

Am J Physiol Lung Cell Mol Physiol. 2016 Jan 15;310(2):L175-86. doi: 10.1152/ajplung.00063.2015. Epub 2015 Nov 13.

11.

Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease.

Sontake V, Shanmukhappa SK, DiPasquale BA, Reddy GB, Medvedovic M, Hardie WD, White ES, Madala SK.

J Immunol. 2015 Oct 15;195(8):3978-91. doi: 10.4049/jimmunol.1500963. Epub 2015 Sep 14.

12.

Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis.

Madala SK, Korfhagen TR, Schmidt S, Davidson C, Edukulla R, Ikegami M, Violette SM, Weinreb PH, Sheppard D, Hardie WD.

Am J Physiol Lung Cell Mol Physiol. 2014 Apr 15;306(8):L726-35. doi: 10.1152/ajplung.00357.2013. Epub 2014 Feb 7.

13.

Dual targeting of MEK and PI3K pathways attenuates established and progressive pulmonary fibrosis.

Madala SK, Edukulla R, Phatak M, Schmidt S, Davidson C, Acciani TH, Korfhagen TR, Medvedovic M, Lecras TD, Wagner K, Hardie WD.

PLoS One. 2014 Jan 27;9(1):e86536. doi: 10.1371/journal.pone.0086536. eCollection 2014.

14.

Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis.

Madala SK, Edukulla R, Schmidt S, Davidson C, Ikegami M, Hardie WD.

Am J Respir Cell Mol Biol. 2014 Apr;50(4):777-86. doi: 10.1165/rcmb.2013-0042OC.

15.

Targeted overexpression of TGF-α in the corneal epithelium of adult transgenic mice induces changes in anterior segment morphology and activates noncanonical Wnt signaling.

Yuan Y, Yeh LK, Liu H, Yamanaka O, Hardie WD, Kao WW, Liu CY.

Invest Ophthalmol Vis Sci. 2013 Mar 11;54(3):1829-37. doi: 10.1167/iovs.12-11477.

16.

Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis.

Madala SK, Edukulla R, Davis KR, Schmidt S, Davidson C, Kitzmiller JA, Hardie WD, Korfhagen TR.

Respir Res. 2012 Jun 22;13:51. doi: 10.1186/1465-9921-13-51.

17.

MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation.

Madala SK, Schmidt S, Davidson C, Ikegami M, Wert S, Hardie WD.

Am J Respir Cell Mol Biol. 2012 Mar;46(3):380-8. doi: 10.1165/rcmb.2011-0237OC. Epub 2011 Oct 20.

18.

Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease.

Kramer EL, Hardie WD, Mushaben EM, Acciani TH, Pastura PA, Korfhagen TR, Hershey GK, Whitsett JA, Le Cras TD.

J Appl Physiol (1985). 2011 Dec;111(6):1760-7. doi: 10.1152/japplphysiol.00737.2011. Epub 2011 Sep 8.

19.

Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice.

Madala SK, Maxfield MD, Davidson CR, Schmidt SM, Garry D, Ikegami M, Hardie WD, Glasser SW.

Pulm Med. 2011;2011:653524. doi: 10.1155/2011/653524. Epub 2011 Mar 21.

20.

Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma.

Le Cras TD, Acciani TH, Mushaben EM, Kramer EL, Pastura PA, Hardie WD, Korfhagen TR, Sivaprasad U, Ericksen M, Gibson AM, Holtzman MJ, Whitsett JA, Hershey GK.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L414-21. doi: 10.1152/ajplung.00346.2010. Epub 2010 Dec 17.

21.

Signaling pathways in the epithelial origins of pulmonary fibrosis.

Hardie WD, Hagood JS, Dave V, Perl AK, Whitsett JA, Korfhagen TR, Glasser S.

Cell Cycle. 2010 Jul 15;9(14):2769-76. Epub 2010 Jul 3. Review.

22.

Pathogenesis of Interstitial Lung Disease in Children and Adults.

Glasser SW, Hardie WD, Hagood JS.

Pediatr Allergy Immunol Pulmonol. 2010 Mar;23(1):9-14.

23.

Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis.

Le Cras TD, Korfhagen TR, Davidson C, Schmidt S, Fenchel M, Ikegami M, Whitsett JA, Hardie WD.

Am J Pathol. 2010 Feb;176(2):679-86. doi: 10.2353/ajpath.2010.090123. Epub 2009 Dec 30.

24.

Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.

Deshmukh HS, McLachlan A, Atkinson JJ, Hardie WD, Korfhagen TR, Dietsch M, Liu Y, Di PY, Wesselkamper SC, Borchers MT, Leikauf GD.

Am J Respir Crit Care Med. 2009 Nov 1;180(9):834-45. doi: 10.1164/rccm.200903-0328OC. Epub 2009 Aug 6.

25.

Emerging concepts in the pathogenesis of lung fibrosis.

Hardie WD, Glasser SW, Hagood JS.

Am J Pathol. 2009 Jul;175(1):3-16. doi: 10.2353/ajpath.2009.081170. Epub 2009 Jun 4. Review.

26.

Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis.

Korfhagen TR, Le Cras TD, Davidson CR, Schmidt SM, Ikegami M, Whitsett JA, Hardie WD.

Am J Respir Cell Mol Biol. 2009 Nov;41(5):562-72. doi: 10.1165/rcmb.2008-0377OC. Epub 2009 Feb 24.

27.

Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice.

Kramer EL, Mushaben EM, Pastura PA, Acciani TH, Deutsch GH, Khurana Hershey GK, Korfhagen TR, Hardie WD, Whitsett JA, Le Cras TD.

Am J Respir Cell Mol Biol. 2009 Oct;41(4):415-25. doi: 10.1165/rcmb.2008-0470OC. Epub 2009 Feb 2.

28.

Surfactant-associated protein B is critical to survival in nickel-induced injury in mice.

Bein K, Wesselkamper SC, Liu X, Dietsch M, Majumder N, Concel VJ, Medvedovic M, Sartor MA, Henning LN, Venditto C, Borchers MT, Barchowsky A, Weaver TE, Tichelaar JW, Prows DR, Korfhagen TR, Hardie WD, Bachurski CJ, Leikauf GD.

Am J Respir Cell Mol Biol. 2009 Aug;41(2):226-36. doi: 10.1165/rcmb.2008-0317OC. Epub 2009 Jan 8.

30.

Acceptability and repeatability of spirometry in children using updated ATS/ERS criteria.

Loeb JS, Blower WC, Feldstein JF, Koch BA, Munlin AL, Hardie WD.

Pediatr Pulmonol. 2008 Oct;43(10):1020-4. doi: 10.1002/ppul.20908.

PMID:
18785259
31.

EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis.

Hardie WD, Davidson C, Ikegami M, Leikauf GD, Le Cras TD, Prestridge A, Whitsett JA, Korfhagen TR.

Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1217-25. doi: 10.1152/ajplung.00020.2008. Epub 2008 Apr 18.

32.

Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.

Deshmukh HS, Shaver C, Case LM, Dietsch M, Wesselkamper SC, Hardie WD, Korfhagen TR, Corradi M, Nadel JA, Borchers MT, Leikauf GD.

Am J Respir Cell Mol Biol. 2008 Apr;38(4):446-54. Epub 2007 Nov 15.

33.

Cavitary lung lesions in a 2-year-old child.

McPhail GL, Hardie WD.

Respiration. 2008;76(1):117-8. Epub 2007 Nov 1. No abstract available.

PMID:
17975297
34.

Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.

Hardie WD, Korfhagen TR, Sartor MA, Prestridge A, Medvedovic M, Le Cras TD, Ikegami M, Wesselkamper SC, Davidson C, Dietsch M, Nichols W, Whitsett JA, Leikauf GD.

Am J Respir Cell Mol Biol. 2007 Sep;37(3):309-21. Epub 2007 May 11.

35.

Perinatal increases in TGF-{alpha} disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysis.

Kramer EL, Deutsch GH, Sartor MA, Hardie WD, Ikegami M, Korfhagen TR, Le Cras TD.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L314-27. Epub 2007 Apr 27.

36.

Long-term results of microwave thermotherapy for symptomatic benign prostatic hyperplasia.

Tan AH, Nott L, Hardie WR, Chin JL, Denstedt JD, Razvi H.

J Endourol. 2005 Dec;19(10):1191-5.

PMID:
16359213
37.

TGF-alpha perturbs surfactant homeostasis in vivo.

Ikegami M, Le Cras TD, Hardie WD, Stahlman MT, Whitsett JA, Korfhagen TR.

Am J Physiol Lung Cell Mol Physiol. 2005 Jul;289(1):L34-43. Epub 2005 Mar 11.

38.

Transient induction of TGF-alpha disrupts lung morphogenesis, causing pulmonary disease in adulthood.

Le Cras TD, Hardie WD, Deutsch GH, Albertine KH, Ikegami M, Whitsett JA, Korfhagen TR.

Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L718-29. Epub 2004 Apr 16.

39.

Persistent abnormal lung function after childhood empyema.

Kohn GL, Walston C, Feldstein J, Warner BW, Succop P, Hardie WD.

Am J Respir Med. 2002;1(6):441-5.

PMID:
14720031
40.

Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis.

Hardie WD, Le Cras TD, Jiang K, Tichelaar JW, Azhar M, Korfhagen TR.

Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L741-9. Epub 2003 Dec 5.

41.

Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha.

Le Cras TD, Hardie WD, Fagan K, Whitsett JA, Korfhagen TR.

Am J Physiol Lung Cell Mol Physiol. 2003 Nov;285(5):L1046-54. Epub 2003 Aug 1.

42.

Pathogenomic mechanisms for particulate matter induction of acute lung injury and inflammation in mice.

Leikauf GD, McDowell SA, Wesselkamper SC, Miller CR, Hardie WD, Gammon K, Biswas PP, Korfhagen TR, Bachurski CJ, Wiest JS, Willeke K, Bingham E, Leikauf JE, Aronow BJ, Prows DR.

Res Rep Health Eff Inst. 2001 Dec;(105):5-58; discussion 59-71.

PMID:
11954676
43.

Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha.

Hardie WD, Prows DR, Piljan-Gentle A, Dunlavy MR, Wesselkamper SC, Leikauf GD, Korfhagen TR.

Am J Respir Cell Mol Biol. 2002 Apr;26(4):430-7.

PMID:
11919079
44.

Acute lung injury: functional genomics and genetic susceptibility.

Leikauf GD, McDowell SA, Wesselkamper SC, Hardie WD, Leikauf JE, Korfhagen TR, Prows DR.

Chest. 2002 Mar;121(3 Suppl):70S-75S.

PMID:
11893692
45.

Functional genomics of oxidant-induced lung injury.

Leikauf GD, McDowell SA, Bachurski CJ, Aronow BJ, Gammon K, Wesselkamper SC, Hardie W, Wiest JS, Leikauf JE, Korfhagen TR, Prows DR.

Adv Exp Med Biol. 2001;500:479-87. Review.

PMID:
11764985
46.

Dose-dependent lung remodeling in transgenic mice expressing transforming growth factor-alpha.

Hardie WD, Piljan-Gentle A, Dunlavy MR, Ikegami M, Korfhagen TR.

Am J Physiol Lung Cell Mol Physiol. 2001 Nov;281(5):L1088-94.

47.

Use of the internet for self-education by patients with prostate cancer.

Pautler SE, Tan JK, Dugas GR, Pus N, Ferri M, Hardie WR, Chin JL.

Urology. 2001 Feb;57(2):230-3.

PMID:
11182326
48.

Declining pediatric subspecialty training and rising educational debt.

Hardie WD, Jaskiewicz JA.

J Pediatr. 2001 Jan;138(1):149-51. No abstract available.

PMID:
11148539
49.
50.

Attenuation of acute lung injury in transgenic mice expressing human transforming growth factor-alpha.

Hardie WD, Prows DR, Leikauf GD, Korfhagen TR.

Am J Physiol. 1999 Nov;277(5):L1045-50. doi: 10.1152/ajplung.1999.277.5.L1045.

PMID:
10564191

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