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Items: 41

1.

A Simple Polymicrobial Biofilm Keratinocyte Colonization Model for Exploring Interactions Between Commensals, Pathogens and Antimicrobials.

Jordana-Lluch E, Garcia V, Kingdon ADH, Singh N, Alexander C, Williams P, Hardie KR.

Front Microbiol. 2020 Feb 26;11:291. doi: 10.3389/fmicb.2020.00291. eCollection 2020.

2.

Dual bioresponsive antibiotic and quorum sensing inhibitor combination nanoparticles for treatment of Pseudomonas aeruginosa biofilms in vitro and ex vivo.

Singh N, Romero M, Travanut A, Monteiro PF, Jordana-Lluch E, Hardie KR, Williams P, Alexander MR, Alexander C.

Biomater Sci. 2019 Sep 24;7(10):4099-4111. doi: 10.1039/c9bm00773c.

PMID:
31355397
3.

The fitness burden imposed by synthesising quorum sensing signals.

Ruparell A, Dubern JF, Ortori CA, Harrison F, Halliday NM, Emtage A, Ashawesh MM, Laughton CA, Diggle SP, Williams P, Barrett DA, Hardie KR.

Sci Rep. 2016 Sep 12;6:33101. doi: 10.1038/srep33101.

4.

The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strain.

Baban ST, Kuehne SA, Barketi-Klai A, Cartman ST, Kelly ML, Hardie KR, Kansau I, Collignon A, Minton NP.

PLoS One. 2013 Sep 23;8(9):e73026. doi: 10.1371/journal.pone.0073026. eCollection 2013.

5.

Impact of an educational intervention upon the hand hygiene compliance of children.

Randle J, Metcalfe J, Webb H, Luckett JC, Nerlich B, Vaughan N, Segal JI, Hardie KR.

J Hosp Infect. 2013 Nov;85(3):220-5. doi: 10.1016/j.jhin.2013.07.013. Epub 2013 Sep 6.

PMID:
24080083
6.

A novel virulence strategy for Pseudomonas aeruginosa mediated by an autotransporter with arginine-specific aminopeptidase activity.

Luckett JC, Darch O, Watters C, Abuoun M, Wright V, Paredes-Osses E, Ward J, Goto H, Heeb S, Pommier S, Rumbaugh KP, Cámara M, Hardie KR.

PLoS Pathog. 2012;8(8):e1002854. doi: 10.1371/journal.ppat.1002854. Epub 2012 Aug 23.

7.

In Helicobacter pylori auto-inducer-2, but not LuxS/MccAB catalysed reverse transsulphuration, regulates motility through modulation of flagellar gene transcription.

Shen F, Hobley L, Doherty N, Loh JT, Cover TL, Sockett RE, Hardie KR, Atherton JC.

BMC Microbiol. 2010 Aug 6;10:210. doi: 10.1186/1471-2180-10-210.

8.

Quantitative liquid chromatography-tandem mass spectrometry profiling of activated methyl cycle metabolites involved in LuxS-dependent quorum sensing in Escherichia coli.

Halliday NM, Hardie KR, Williams P, Winzer K, Barrett DA.

Anal Biochem. 2010 Aug;403(1-2):20-9. doi: 10.1016/j.ab.2010.04.021. Epub 2010 Apr 22.

PMID:
20417170
9.

Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen.

O'Toole PW, Snelling WJ, Canchaya C, Forde BM, Hardie KR, Josenhans C, Graham RLj, McMullan G, Parkhill J, Belda E, Bentley SD.

BMC Genomics. 2010 Mar 10;11:164. doi: 10.1186/1471-2164-11-164.

10.

In Helicobacter pylori, LuxS is a key enzyme in cysteine provision through a reverse transsulfuration pathway.

Doherty NC, Shen F, Halliday NM, Barrett DA, Hardie KR, Winzer K, Atherton JC.

J Bacteriol. 2010 Mar;192(5):1184-92. doi: 10.1128/JB.01372-09. Epub 2010 Jan 8.

11.

AI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro.

Holmes K, Tavender TJ, Winzer K, Wells JM, Hardie KR.

BMC Microbiol. 2009 Oct 8;9:214. doi: 10.1186/1471-2180-9-214.

12.

Growth deficiencies of Neisseria meningitidis pfs and luxS mutants are not due to inactivation of quorum sensing.

Heurlier K, Vendeville A, Halliday N, Green A, Winzer K, Tang CM, Hardie KR.

J Bacteriol. 2009 Feb;191(4):1293-302. doi: 10.1128/JB.01170-08. Epub 2008 Dec 12. Erratum in: J Bacteriol. 2009 Aug;191(16):5332.

13.

LuxS-independent formation of AI-2 from ribulose-5-phosphate.

Tavender TJ, Halliday NM, Hardie KR, Winzer K.

BMC Microbiol. 2008 Jun 18;8:98. doi: 10.1186/1471-2180-8-98.

14.

Establishing bacterial communities by 'word of mouth': LuxS and autoinducer 2 in biofilm development.

Hardie KR, Heurlier K.

Nat Rev Microbiol. 2008 Aug;6(8):635-43. doi: 10.1038/nrmicro1916. Epub 2008 Jun 9. Review.

PMID:
18536728
15.

Functional association between the Helicobacter pylori virulence factors VacA and CagA.

Argent RH, Thomas RJ, Letley DP, Rittig MG, Hardie KR, Atherton JC.

J Med Microbiol. 2008 Feb;57(Pt 2):145-50. doi: 10.1099/jmm.0.47465-0.

PMID:
18201978
16.
17.

All subtypes of the cytotoxin VacA adsorb to the surface of Helicobacter pylori post-secretion.

Fitchen N, Letley DP, O'Shea P, Atherton JC, Williams P, Hardie KR.

J Med Microbiol. 2005 Jul;54(Pt 7):621-30.

PMID:
15947426
18.

Making 'sense' of metabolism: autoinducer-2, LuxS and pathogenic bacteria.

Vendeville A, Winzer K, Heurlier K, Tang CM, Hardie KR.

Nat Rev Microbiol. 2005 May;3(5):383-96. Review.

PMID:
15864263
19.

LuxS and autoinducer-2: their contribution to quorum sensing and metabolism in bacteria.

Winzer K, Hardie KR, Williams P.

Adv Appl Microbiol. 2003;53:291-396. Review. No abstract available.

PMID:
14696323
20.

Functional complementation of E. coli secD and secG mutants by Helicobacter pylori homologues.

Fitchen N, Williams P, Hardie KR.

FEMS Microbiol Lett. 2003 Dec 5;229(1):57-63.

21.

Electrostatic sensor for identifying interactions between peptides and bacterial membranes.

Fitchen N, O'Shea P, Williams P, Hardie KR.

Mol Immunol. 2003 Nov;40(7):407-11.

PMID:
14568386
22.

NapA protects Helicobacter pylori from oxidative stress damage, and its production is influenced by the ferric uptake regulator.

Cooksley C, Jenks PJ, Green A, Cockayne A, Logan RPH, Hardie KR.

J Med Microbiol. 2003 Jun;52(Pt 6):461-469. doi: 10.1099/jmm.0.05070-0.

PMID:
12748264
23.

Autoinducer 2 activity in Escherichia coli culture supernatants can be actively reduced despite maintenance of an active synthase, LuxS.

Hardie KR, Cooksley C, Green AD, Winzer K.

Microbiology. 2003 Mar;149(Pt 3):715-728. doi: 10.1099/mic.0.25853-0.

PMID:
12634340
25.

Bacterial cell-to-cell communication: sorry, can't talk now - gone to lunch!

Winzer K, Hardie KR, Williams P.

Curr Opin Microbiol. 2002 Apr;5(2):216-22. Review.

PMID:
11934621
26.

LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone.

Winzer K, Hardie KR, Burgess N, Doherty N, Kirke D, Holden MTG, Linforth R, Cornell KA, Taylor AJ, Hill PJ, Williams P.

Microbiology. 2002 Apr;148(Pt 4):909-922. doi: 10.1099/00221287-148-4-909.

PMID:
11932438
27.

Role of Neisseria meningitidis luxS in cell-to-cell signaling and bacteremic infection.

Winzer K, Sun YH, Green A, Delory M, Blackley D, Hardie KR, Baldwin TJ, Tang CM.

Infect Immun. 2002 Apr;70(4):2245-8.

28.

LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence.

Burgess NA, Kirke DF, Williams P, Winzer K, Hardie KR, Meyers NL, Aduse-Opoku J, Curtis MA, Cámara M.

Microbiology. 2002 Mar;148(Pt 3):763-772. doi: 10.1099/00221287-148-3-763.

PMID:
11882711
29.
30.

In vitro biosynthesis of the Pseudomonas aeruginosa quorum-sensing signal molecule N-butanoyl-L-homoserine lactone.

Jiang Y, Camara M, Chhabra SR, Hardie KR, Bycroft BW, Lazdunski A, Salmond GP, Stewart GS, Williams P.

Mol Microbiol. 1998 Apr;28(1):193-203.

31.

Analysis of the carbapenem gene cluster of Erwinia carotovora: definition of the antibiotic biosynthetic genes and evidence for a novel beta-lactam resistance mechanism.

McGowan SJ, Sebaihia M, O'Leary S, Hardie KR, Williams P, Stewart GS, Bycroft BW, Salmond GP.

Mol Microbiol. 1997 Nov;26(3):545-56.

32.

Recent progress and future directions in studies of the main terminal branch of the general secretory pathway in Gram-negative bacteria--a review.

Pugsley AP, Francetic O, Possot OM, Sauvonnet N, Hardie KR.

Gene. 1997 Jun 11;192(1):13-9. Review.

PMID:
9224869
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36.

Vibrio spp. secrete proaerolysin as a folded dimer without the need for disulphide bond formation.

Hardie KR, Schulze A, Parker MW, Buckley JT.

Mol Microbiol. 1995 Sep;17(6):1035-44.

PMID:
8594324
37.

The C-terminal peptide produced upon proteolytic activation of the cytolytic toxin aerolysin is not involved in channel formation.

van der Goot FG, Hardie KR, Parker MW, Buckley JT.

J Biol Chem. 1994 Dec 2;269(48):30496-501.

38.
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40.

Transferrin-binding ability of invasive and commensal isolates of Haemophilus spp.

Hardie KR, Adams RA, Towner KJ.

J Med Microbiol. 1993 Sep;39(3):218-24.

PMID:
8366521
41.

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