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Items: 24

1.

Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma.

Williams PA, Braine CE, Kizhatil K, Foxworth NE, Tolman NG, Harder JM, Scott RA, Sousa GL, Panitch A, Howell GR, John SWM.

Mol Neurodegener. 2019 Jan 22;14(1):6. doi: 10.1186/s13024-018-0303-3.

2.

Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice.

Harder JM, Williams PA, Soto I, Foxworth NE, Fernandes KA, Freeburg NF, Libby RT, John SWM.

Cell Death Dis. 2018 Jun 13;9(6):705. doi: 10.1038/s41419-018-0705-8.

3.

Nicotinamide treatment robustly protects from inherited mouse glaucoma.

Williams PA, Harder JM, Cardozo BH, Foxworth NE, John SWM.

Commun Integr Biol. 2018 Jan 19;11(1):e1356956. doi: 10.1080/19420889.2017.1356956. eCollection 2018.

4.

Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma.

Williams PA, Harder JM, John SWM.

J Glaucoma. 2017 Dec;26(12):1161-1168. doi: 10.1097/IJG.0000000000000767. Review.

5.

Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma.

Williams PA, Harder JM, Foxworth NE, Cardozo BH, Cochran KE, John SWM.

Front Neurosci. 2017 Apr 25;11:232. doi: 10.3389/fnins.2017.00232. eCollection 2017.

6.

Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective.

Harder JM, Braine CE, Williams PA, Zhu X, MacNicoll KH, Sousa GL, Buchanan RA, Smith RS, Libby RT, Howell GR, John SWM.

Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3839-E3848. doi: 10.1073/pnas.1608769114. Epub 2017 Apr 26.

7.

Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice.

Williams PA, Harder JM, Foxworth NE, Cochran KE, Philip VM, Porciatti V, Smithies O, John SW.

Science. 2017 Feb 17;355(6326):756-760. doi: 10.1126/science.aal0092.

8.

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease.

Graham LC, Harder JM, Soto I, de Vries WN, John SW, Howell GR.

Sci Rep. 2016 Feb 18;6:21568. doi: 10.1038/srep21568.

9.

Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities.

Fernandes KA, Harder JM, Williams PA, Rausch RL, Kiernan AE, Nair KS, Anderson MG, John SW, Howell GR, Libby RT.

Exp Eye Res. 2015 Dec;141:42-56. doi: 10.1016/j.exer.2015.06.019. Epub 2015 Jun 24. Review.

10.

Corrigendum: a common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.

Aung T, Ozaki M, Mizoguchi T, Allingham RR, Li Z, Haripriya A, Nakano S, Uebe S, Harder JM, Chan AS, Lee MC, Burdon KP, Astakhov YS, Abu-Amero KK, Zenteno JC, Nilgün Y, Zarnowski T, Pakravan M, Safieh LA, Jia L, Wang YX, Williams S, Paoli D, Schlottmann PG, Huang L, Sim KS, Foo JN, Nakano M, Ikeda Y, Kumar RS, Ueno M, Manabe S, Hayashi K, Kazama S, Ideta R, Mori Y, Miyata K, Sugiyama K, Higashide T, Chihara E, Inoue K, Ishiko S, Yoshida A, Yanagi M, Kiuchi Y, Aihara M, Ohashi T, Sakurai T, Sugimoto T, Chuman H, Matsuda F, Yamashiro K, Gotoh N, Miyake M, Astakhov SY, Osman EA, Al-Obeidan SA, Owaidhah O, Al-Jasim L, Shahwan SA, Fogarty RA, Leo P, Yetkin Y, Oğuz Ç, Kanavi MR, Beni AN, Yazdani S, Akopov EL, Toh KY, Howell GR, Orr AC, Goh Y, Meah WY, Peh SQ, Kosior-Jarecka E, Lukasik U, Krumbiegel M, Vithana EN, Wong TY, Liu Y, Koch AE, Challa P, Rautenbach RM, Mackey DA, Hewitt AW, Mitchell P, Wang JJ, Ziskind A, Carmichael T, Ramakrishnan R, Narendran K, Venkatesh R, Vijayan S, Zhao P, Chen X, Guadarrama-Vallejo D, Cheng CY, Perera SA, Husain R, Ho SL, Welge-Luessen UC, Mardin C, Schloetzer-Schrehardt U, Hillmer AM, Herms S, Moebus S, Nöthen MM, Weisschuh N, Shetty R, Ghosh A, Teo YY, Brown MA, Lischinsky I; Blue Mountains Eye Study GWAS Team; Wellcome Trust Case Control Consortium 2, Crowston JG, Coote M, Zhao B, Sang J, Zhang N, You Q, Vysochinskaya V, Founti P, Chatzikyriakidou A, Lambropoulos A, Anastasopoulos E, Coleman AL, Wilson MR, Rhee DJ, Kang JH, May-Bolchakova I, Heegaard S, Mori K, Alward WL, Jonas JB, Xu L, Liebmann JM, Chowbay B, Schaeffeler E, Schwab M, Lerner F, Wang N, Yang Z, Frezzotti P, Kinoshita S, Fingert JH, Inatani M, Tashiro K, Reis A, Edward DP, Pasquale LR, Kubota T, Wiggs JL, Pasutto F, Topouzis F, Dubina M, Craig JE, Yoshimura N, Sundaresan P, John SW, Ritch R, Hauser MA, Khor CC.

Nat Genet. 2015 Jun;47(6):689. doi: 10.1038/ng0615-689c. No abstract available.

PMID:
26018902
11.

A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.

Aung T, Ozaki M, Mizoguchi T, Allingham RR, Li Z, Haripriya A, Nakano S, Uebe S, Harder JM, Chan AS, Lee MC, Burdon KP, Astakhov YS, Abu-Amero KK, Zenteno JC, Nilgün Y, Zarnowski T, Pakravan M, Safieh LA, Jia L, Wang YX, Williams S, Paoli D, Schlottmann PG, Huang L, Sim KS, Foo JN, Nakano M, Ikeda Y, Kumar RS, Ueno M, Manabe S, Hayashi K, Kazama S, Ideta R, Mori Y, Miyata K, Sugiyama K, Higashide T, Chihara E, Inoue K, Ishiko S, Yoshida A, Yanagi M, Kiuchi Y, Aihara M, Ohashi T, Sakurai T, Sugimoto T, Chuman H, Matsuda F, Yamashiro K, Gotoh N, Miyake M, Astakhov SY, Osman EA, Al-Obeidan SA, Owaidhah O, Al-Jasim L, Al Shahwan S, Fogarty RA, Leo P, Yetkin Y, Oğuz Ç, Kanavi MR, Beni AN, Yazdani S, Akopov EL, Toh KY, Howell GR, Orr AC, Goh Y, Meah WY, Peh SQ, Kosior-Jarecka E, Lukasik U, Krumbiegel M, Vithana EN, Wong TY, Liu Y, Koch AE, Challa P, Rautenbach RM, Mackey DA, Hewitt AW, Mitchell P, Wang JJ, Ziskind A, Carmichael T, Ramakrishnan R, Narendran K, Venkatesh R, Vijayan S, Zhao P, Chen X, Guadarrama-Vallejo D, Cheng CY, Perera SA, Husain R, Ho SL, Welge-Luessen UC, Mardin C, Schloetzer-Schrehardt U, Hillmer AM, Herms S, Moebus S, Nöthen MM, Weisschuh N, Shetty R, Ghosh A, Teo YY, Brown MA, Lischinsky I; Blue Mountains Eye Study GWAS Team; Wellcome Trust Case Control Consortium 2, Crowston JG, Coote M, Zhao B, Sang J, Zhang N, You Q, Vysochinskaya V, Founti P, Chatzikyriakidou A, Lambropoulos A, Anastasopoulos E, Coleman AL, Wilson MR, Rhee DJ, Kang JH, May-Bolchakova I, Heegaard S, Mori K, Alward WL, Jonas JB, Xu L, Liebmann JM, Chowbay B, Schaeffeler E, Schwab M, Lerner F, Wang N, Yang Z, Frezzotti P, Kinoshita S, Fingert JH, Inatani M, Tashiro K, Reis A, Edward DP, Pasquale LR, Kubota T, Wiggs JL, Pasutto F, Topouzis F, Dubina M, Craig JE, Yoshimura N, Sundaresan P, John SW, Ritch R, Hauser MA, Khor CC.

Nat Genet. 2015 Apr;47(4):387-92. doi: 10.1038/ng.3226. Epub 2015 Feb 23. Erratum in: Nat Genet. 2015 Jun;47(6):689.

12.

Animal models of exfoliation syndrome, now and future.

John SW, Harder JM, Fingert JH, Anderson MG.

J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S68-72. doi: 10.1097/IJG.0000000000000121. Review.

13.

Fractional exhaled nitric oxide of at least 100 ppb and implications for future asthma research.

Chipps BE, Anderson CT, Harder JM.

Ann Allergy Asthma Immunol. 2014 Jul;113(1):118-9. doi: 10.1016/j.anai.2014.05.005. No abstract available.

PMID:
24950849
14.

DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury.

Fernandes KA, Harder JM, John SW, Shrager P, Libby RT.

Neurobiol Dis. 2014 Sep;69:108-16. doi: 10.1016/j.nbd.2014.05.015. Epub 2014 May 27.

15.

JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells.

Fernandes KA, Harder JM, Kim J, Libby RT.

Exp Eye Res. 2013 Jul;112:106-17. doi: 10.1016/j.exer.2013.04.021. Epub 2013 May 3.

16.

Deficiency in Bim, Bid and Bbc3 (Puma) do not prevent axonal injury induced death.

Harder JM, Libby RT.

Cell Death Differ. 2013 Jan;20(1):182. doi: 10.1038/cdd.2012.119. Epub 2012 Sep 21. No abstract available.

17.

BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells.

Harder JM, Ding Q, Fernandes KA, Cherry JD, Gan L, Libby RT.

Mol Cell Neurosci. 2012 Aug;51(1-2):53-9. doi: 10.1016/j.mcn.2012.07.006. Epub 2012 Jul 24.

18.

The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice.

Harder JM, Fernandes KA, Libby RT.

Sci Rep. 2012;2:530. doi: 10.1038/srep00530. Epub 2012 Jul 25.

19.

JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death.

Fernandes KA, Harder JM, Fornarola LB, Freeman RS, Clark AF, Pang IH, John SW, Libby RT.

Neurobiol Dis. 2012 May;46(2):393-401. doi: 10.1016/j.nbd.2012.02.003. Epub 2012 Feb 14.

20.

BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina.

Harder JM, Libby RT.

Mol Neurodegener. 2011 Jul 15;6:50. doi: 10.1186/1750-1326-6-50.

21.

Phenotypic expressions of childhood wheezing and asthma: implications for therapy.

Chipps BE, Bacharier LB, Harder JM.

J Pediatr. 2011 Jun;158(6):878-884.e1. doi: 10.1016/j.jpeds.2011.01.057. Epub 2011 Mar 22. No abstract available.

PMID:
21429508
22.

Antihistamine treatment for allergic rhinitis: different routes, different outcomes?

Chipps BE, Harder JM.

Allergy Asthma Proc. 2009 Nov-Dec;30(6):589-94. doi: 10.2500/aap.2009.30.3287.

PMID:
20031005
23.

Targeted interventions for difficult-to-treat asthma.

Chipps BE, Harder JM.

Expert Opin Ther Targets. 2007 Jan;11(1):11-20. Review.

PMID:
17150031
24.

Dose counting and the use of pressurized metered-dose inhalers: running on empty.

Sander N, Fusco-Walkert SJ, Harder JM, Chipps BE.

Ann Allergy Asthma Immunol. 2006 Jul;97(1):34-8.

PMID:
16892778

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