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Items: 1 to 20 of 110


Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells.

Harder BG, Peng S, Sereduk CP, Sodoma AM, Kitange GJ, Loftus JC, Sarkaria JN, Tran NL.

Mol Med. 2019 Nov 14;25(1):49. doi: 10.1186/s10020-019-0116-z.


Social Connectedness Factors that Facilitate Use of Healthcare Services: Comparison of Transgender and Gender Nonconforming and Cisgender Adolescents.

Taliaferro LA, Harder BM, Lampe NM, Carter SK, Rider GN, Eisenberg ME.

J Pediatr. 2019 Aug;211:172-178. doi: 10.1016/j.jpeds.2019.04.024. Epub 2019 May 10.


Healthworlds, Cultural Health Toolkits, and Choice: How Acculturation Affects Patients' Views of Prescription Drugs and Prescription Drug Advertising.

Adams C, Harder BM, Chatterjee A, Hayes Mathias L.

Qual Health Res. 2019 Aug;29(10):1419-1432. doi: 10.1177/1049732319827282. Epub 2019 Feb 9.


Nonclinical safety assessment of a human interleukin-22FC IG fusion protein demonstrates in vitro to in vivo and cross-species translatability.

Lee DW, Zhong S, Pai R, Rae J, Sukumaran S, Stefanich EG, Lutman J, Doudement E, Wang X, Harder B, Lekkerkerker A, Herman A, Ouyang W, Danilenko DM.

Pharmacol Res Perspect. 2018 Nov 15;6(6):e00434. doi: 10.1002/prp2.434. eCollection 2018 Dec.


Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma.

Harder BG, Blomquist MR, Wang J, Kim AJ, Woodworth GF, Winkles JA, Loftus JC, Tran NL.

Front Oncol. 2018 Oct 23;8:462. doi: 10.3389/fonc.2018.00462. eCollection 2018. Review.


The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance.

Hersh DS, Harder BG, Roos A, Peng S, Heath JE, Legesse T, Kim AJ, Woodworth GF, Tran NL, Winkles JA.

Neuro Oncol. 2018 Sep 3;20(10):1321-1330. doi: 10.1093/neuonc/noy063.


Beyond unequal access: Acculturation, race, and resistance to pharmaceuticalization in the United States.

Adams C, Chatterjee A, Harder BM, Mathias LH.

SSM Popul Health. 2018 Apr 12;4:350-357. doi: 10.1016/j.ssmph.2018.04.003. eCollection 2018 Apr.


Bat detective-Deep learning tools for bat acoustic signal detection.

Mac Aodha O, Gibb R, Barlow KE, Browning E, Firman M, Freeman R, Harder B, Kinsey L, Mead GR, Newson SE, Pandourski I, Parsons S, Russ J, Szodoray-Paradi A, Szodoray-Paradi F, Tilova E, Girolami M, Brostow G, Jones KE.

PLoS Comput Biol. 2018 Mar 8;14(3):e1005995. doi: 10.1371/journal.pcbi.1005995. eCollection 2018 Mar.


Low-level arsenic causes proteotoxic stress and not oxidative stress.

Dodson M, de la Vega MR, Harder B, Castro-Portuguez R, Rodrigues SD, Wong PK, Chapman E, Zhang DD.

Toxicol Appl Pharmacol. 2018 Feb 15;341:106-113. doi: 10.1016/j.taap.2018.01.014. Epub 2018 Feb 3.


Temperature-dependent dynamic control of the TCA cycle increases volumetric productivity of itaconic acid production by Escherichia coli.

Harder BJ, Bettenbrock K, Klamt S.

Biotechnol Bioeng. 2018 Jan;115(1):156-164. doi: 10.1002/bit.26446. Epub 2017 Oct 6.


Arsenic Compromises Both p97 and Proteasome Functions.

Tillotson J, Zerio CJ, Harder B, Ambrose AJ, Jung KS, Kang M, Zhang DD, Chapman E.

Chem Res Toxicol. 2017 Jul 17;30(7):1508-1514. doi: 10.1021/acs.chemrestox.7b00158. Epub 2017 Jul 7.


Brusatol overcomes chemoresistance through inhibition of protein translation.

Harder B, Tian W, La Clair JJ, Tan AC, Ooi A, Chapman E, Zhang DD.

Mol Carcinog. 2017 May;56(5):1493-1500. doi: 10.1002/mc.22609. Epub 2017 Feb 8.


Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients.

Schuster AK, Harder BC, Schlichtenbrede FC, Jarczok MN, Tesarz J.

Cochrane Database Syst Rev. 2016 Nov 14;11:CD011503. Review.


Model-based metabolic engineering enables high yield itaconic acid production by Escherichia coli.

Harder BJ, Bettenbrock K, Klamt S.

Metab Eng. 2016 Nov;38:29-37. doi: 10.1016/j.ymben.2016.05.008. Epub 2016 Jun 4.


Best practice recommendations for the transfer of cell-based assays for the measurement of neutralizing anti-drug antibodies.

Belouski SS, Born D, Jacques S, Harder B, Reynhardt K, Kaliyaperumal A, Gupta S.

Bioanalysis. 2016 Sep;8(17):1845-57. doi: 10.4155/bio-2016-4998. Epub 2016 Aug 15.


Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle-age period.

Corenblum MJ, Ray S, Remley QW, Long M, Harder B, Zhang DD, Barnes CA, Madhavan L.

Aging Cell. 2016 Aug;15(4):725-36. doi: 10.1111/acel.12482. Epub 2016 Apr 20.


Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention.

Harder B, Jiang T, Wu T, Tao S, Rojo de la Vega M, Tian W, Chapman E, Zhang DD.

Biochem Soc Trans. 2015 Aug;43(4):680-6. doi: 10.1042/BST20150020. Epub 2015 Aug 3. Review.


p62 links autophagy and Nrf2 signaling.

Jiang T, Harder B, Rojo de la Vega M, Wong PK, Chapman E, Zhang DD.

Free Radic Biol Med. 2015 Nov;88(Pt B):199-204. doi: 10.1016/j.freeradbiomed.2015.06.014. Epub 2015 Jun 24. Review.


[Living liver donor: indications and technical aspects].

Nadalin S, Capobianco I, Königsrainer I, Harder B, Königsrainer A.

Chirurg. 2015 Jun;86(6):609-21; quiz 622. doi: 10.1007/s00104-015-0017-9. Review. German.


Hospital quality reporting by US News & World Report: why, how, and what's ahead.

Harder B, Comarow A.

JAMA. 2015 May 19;313(19):1903-4. doi: 10.1001/jama.2015.4566. No abstract available.


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