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Noninvasive Immunohistochemical Diagnosis and Novel MUC1 Mutations Causing Autosomal Dominant Tubulointerstitial Kidney Disease.

Živná M, Kidd K, Přistoupilová A, Barešová V, DeFelice M, Blumenstiel B, Harden M, Conlon P, Lavin P, Connaughton DM, Hartmannová H, Hodaňová K, Stránecký V, Vrbacká A, Vyleťal P, Živný J, Votruba M, Sovová J, Hůlková H, Robins V, Perry R, Wenzel A, Beck BB, Seeman T, Viklický O, Rajnochová-Bloudíčková S, Papagregoriou G, Deltas CC, Alper SL, Greka A, Bleyer AJ, Kmoch S.

J Am Soc Nephrol. 2018 Jul 2. pii: ASN.2018020180. doi: 10.1681/ASN.2018020180. [Epub ahead of print]


Updated meta-review of evidence on support for carers.

Dalton J, Thomas S, Harden M, Eastwood A, Parker G.

J Health Serv Res Policy. 2018 Jul;23(3):196-207. doi: 10.1177/1355819618766559. Epub 2018 May 16.


Integrated Care to Address the Physical Health Needs of People with Severe Mental Illness: A Mapping Review of the Recent Evidence on Barriers, Facilitators and Evaluations.

Rodgers M, Dalton J, Harden M, Street A, Parker G, Eastwood A.

Int J Integr Care. 2018 Jan 25;18(1):9. doi: 10.5334/ijic.2605.


High-throughput non-invasive prenatal testing for fetal rhesus D status in RhD-negative women not known to be sensitised to the RhD antigen: a systematic review and economic evaluation.

Saramago P, Yang H, Llewellyn A, Walker R, Harden M, Palmer S, Griffin S, Simmonds M.

Health Technol Assess. 2018 Mar;22(13):1-172. doi: 10.3310/hta22130.


Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma.

Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, Eisenhaure T, Gjini E, Stevens J, Lane WJ, Javeri I, Nellaiappan K, Salazar AM, Daley H, Seaman M, Buchbinder EI, Yoon CH, Harden M, Lennon N, Gabriel S, Rodig SJ, Barouch DH, Aster JC, Getz G, Wucherpfennig K, Neuberg D, Ritz J, Lander ES, Fritsch EF, Hacohen N, Wu CJ.

Nature. 2018 Mar 14;555(7696):402. doi: 10.1038/nature25145.


The provision of services in the UK for UK armed forces veterans with PTSD: a rapid evidence synthesis.

Dalton J, Thomas S, Melton H, Harden M, Eastwood A.

Southampton (UK): NIHR Journals Library; 2018 Feb.


An Evaluation of Supramaximally Loaded Eccentric Leg Press Exercise.

Harden M, Wolf A, Russell M, Hicks KM, French D, Howatson G.

J Strength Cond Res. 2018 Feb 20. doi: 10.1519/JSC.0000000000002497. [Epub ahead of print]


The influence of hospitalisation on the initiation, continuation and discontinuation of benzodiazepines and Z-drugs - an observational study.

Grimmsmann T, Harden M, Fiß T, Himmel W.

Swiss Med Wkly. 2018 Feb 14;148:w14590. doi: 10.4414/smw.2018.14590. eCollection 2018.


Evaluating progestogens for prevention of preterm birth international collaborative (EPPPIC) individual participant data (IPD) meta-analysis: protocol.

Stewart LA, Simmonds M, Duley L, Dietz KC, Harden M, Hodkinson A, Llewellyn A, Sharif S, Walker R, Wright K; EPPPIC group.

Syst Rev. 2017 Nov 28;6(1):235. doi: 10.1186/s13643-017-0600-x. Review.


Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people: systematic review and economic evaluation.

Duarte A, Mebrahtu T, Goncalves PS, Harden M, Murphy R, Palmer S, Woolacott N, Rodgers M, Rothery C.

Health Technol Assess. 2017 Nov;21(64):1-244. doi: 10.3310/hta21640. Review.


Certolizumab pegol and secukinumab for treating active psoriatic arthritis following inadequate response to disease-modifying antirheumatic drugs: a systematic review and economic evaluation.

Corbett M, Chehadah F, Biswas M, Moe-Byrne T, Palmer S, Soares M, Walton M, Harden M, Ho P, Woolacott N, Bojke L.

Health Technol Assess. 2017 Oct;21(56):1-326. doi: 10.3310/hta21560. Review.


A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.

Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Macías H, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Caulkins L, Puppala S, Fontanillas P, Williams AL, Bonàs-Guarch S, Hartl C, Ripke S; Diabetes Prevention Program Research Group, Tooley K, Lane J, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza-Caamal E, Contreras-Cubas C, González-Villalpando ME, Cruz-Bautista I, Muñoz-Hernández L, Gómez-Velasco D, Alvirde U, Henderson BE, Wilkens LR, Le Marchand L, Arellano-Campos O, Riba L, Harden M; Broad Genomics Platform, Gabriel S; T2D-GENES Consortium, Abboud HE, Cortes ML, Revilla-Monsalve C, Islas-Andrade S, Soberon X, Curran JE, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis CL, Bell GI, Boehnke M, Blangero J, Duggirala R, Saxena R, MacArthur D, Ferrer J, McCarroll SA, Torrents D, Knowler WC, Baier LJ, Burtt N, González-Villalpando C, Haiman CA, Aguilar-Salinas CA, Tusié-Luna T, Flannick J, Jacobs SBR, Orozco L, Altshuler D, Florez JC; SIGMA T2D Genetics Consortium.

Diabetes. 2017 Nov;66(11):2903-2914. doi: 10.2337/db17-0187. Epub 2017 Aug 24.


An immunogenic personal neoantigen vaccine for patients with melanoma.

Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, Eisenhaure T, Gjini E, Stevens J, Lane WJ, Javeri I, Nellaiappan K, Salazar AM, Daley H, Seaman M, Buchbinder EI, Yoon CH, Harden M, Lennon N, Gabriel S, Rodig SJ, Barouch DH, Aster JC, Getz G, Wucherpfennig K, Neuberg D, Ritz J, Lander ES, Fritsch EF, Hacohen N, Wu CJ.

Nature. 2017 Jul 13;547(7662):217-221. doi: 10.1038/nature22991. Epub 2017 Jul 5. Erratum in: Nature. 2018 Mar 14;555(7696):402.


Human papillomavirus molecular biology.

Harden ME, Munger K.

Mutat Res Rev Mutat Res. 2017 Apr - Jun;772:3-12. doi: 10.1016/j.mrrev.2016.07.002. Epub 2016 Jul 5. Review.


Human papillomavirus 16 E6 and E7 oncoprotein expression alters microRNA expression in extracellular vesicles.

Harden ME, Munger K.

Virology. 2017 Aug;508:63-69. doi: 10.1016/j.virol.2017.05.005. Epub 2017 May 10.


Perturbation of DROSHA and DICER expression by human papillomavirus 16 oncoproteins.

Harden ME, Munger K.

Virology. 2017 Jul;507:192-198. doi: 10.1016/j.virol.2017.04.022. Epub 2017 Apr 24.


Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study.

Schütz E, Fischer A, Beck J, Harden M, Koch M, Wuensch T, Stockmann M, Nashan B, Kollmar O, Matthaei J, Kanzow P, Walson PD, Brockmöller J, Oellerich M.

PLoS Med. 2017 Apr 25;14(4):e1002286. doi: 10.1371/journal.pmed.1002286. eCollection 2017 Apr.


Updated meta-review of evidence on support for carers.

Thomas S, Dalton J, Harden M, Eastwood A, Parker G.

Southampton (UK): NIHR Journals Library; 2017 Mar.


Crizotinib for Untreated Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

Morgan P, Woolacott N, Biswas M, Mebrahtu T, Harden M, Hodgson R.

Pharmacoeconomics. 2017 Sep;35(9):909-919. doi: 10.1007/s40273-017-0497-1. Review.


Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 Oncoproteins.

Harden ME, Prasad N, Griffiths A, Munger K.

MBio. 2017 Jan 3;8(1). pii: e02170-16. doi: 10.1128/mBio.02170-16.


Results of medial patellofemoral ligament reconstruction compared with trochleoplasty plus individual extensor apparatus balancing in patellar instability caused by severe trochlear dysplasia: a systematic review and meta-analysis.

Balcarek P, Rehn S, Howells NR, Eldridge JD, Kita K, Dejour D, Nelitz M, Banke IJ, Lambrecht D, Harden M, Friede T.

Knee Surg Sports Traumatol Arthrosc. 2017 Dec;25(12):3869-3877. doi: 10.1007/s00167-016-4365-x. Epub 2016 Oct 27. Review.


Unexpectedly high incidence of hypothermia before induction of anesthesia in elective surgical patients.

Wetz AJ, Perl T, Brandes IF, Harden M, Bauer M, Bräuer A.

J Clin Anesth. 2016 Nov;34:282-9. doi: 10.1016/j.jclinane.2016.03.065. Epub 2016 May 16.


A Review of Ruxolitinib for the Treatment of Myelofibrosis: A Critique of the Evidence.

Wade R, Hodgson R, Biswas M, Harden M, Woolacott N.

Pharmacoeconomics. 2017 Feb;35(2):203-213. doi: 10.1007/s40273-016-0447-3. Review.


Catechol-O-methyltransferase association with hemoglobin A1c.

Hall KT, Jablonski KA, Chen L, Harden M, Tolkin BR, Kaptchuk TJ, Bray GA, Ridker PM, Florez JC; Diabetes Prevention Program Research Group, Mukamal KJ, Chasman DI.

Metabolism. 2016 Jul;65(7):961-967. doi: 10.1016/j.metabol.2016.04.001. Epub 2016 Apr 14.


Back schools for the treatment of chronic low back pain: possibility of benefit but no convincing evidence after 47 years of research-systematic review and meta-analysis.

Straube S, Harden M, Schröder H, Arendacka B, Fan X, Moore RA, Friede T.

Pain. 2016 Oct;157(10):2160-72. doi: 10.1097/j.pain.0000000000000640. Review.


Integrated care to address the physical health needs of people with severe mental illness: a rapid review.

Rodgers M, Dalton J, Harden M, Street A, Parker G, Eastwood A.

Southampton (UK): NIHR Journals Library; 2016 Apr.


Spontaneous regression of pulmonary metastatic melanoma.

Ong SF, Harden M, Irandoust S, Lee RW.

Respirol Case Rep. 2015 Dec 8;4(1):7-9. doi: 10.1002/rcr2.138. eCollection 2016 Mar.


Developing a methodological framework for organisational case studies: a rapid review and consensus development process.

Rodgers M, Thomas S, Harden M, Parker G, Street A, Eastwood A.

Southampton (UK): NIHR Journals Library; 2016 Jan.


Service user engagement in health service reconfiguration: a rapid evidence synthesis.

Dalton J, Chambers D, Harden M, Street A, Parker G, Eastwood A.

J Health Serv Res Policy. 2016 Jul;21(3):195-205. doi: 10.1177/1355819615623305. Epub 2015 Dec 20. Review.


Diagnostic accuracy of the Whooley questions for the identification of depression: a diagnostic meta-analysis.

Bosanquet K, Bailey D, Gilbody S, Harden M, Manea L, Nutbrown S, McMillan D.

BMJ Open. 2015 Dec 9;5(12):e008913. doi: 10.1136/bmjopen-2015-008913. Review.


A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling.

Patterson HC, Gerbeth C, Thiru P, Vögtle NF, Knoll M, Shahsafaei A, Samocha KE, Huang CX, Harden MM, Song R, Chen C, Kao J, Shi J, Salmon W, Shaul YD, Stokes MP, Silva JC, Bell GW, MacArthur DG, Ruland J, Meisinger C, Lodish HF.

Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):E5679-88. doi: 10.1073/pnas.1517932112. Epub 2015 Oct 5. Erratum in: Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2094.


Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials.

Papandonatos GD, Pan Q, Pajewski NM, Delahanty LM, Peter I, Erar B, Ahmad S, Harden M, Chen L, Fontanillas P; GIANT Consortium, Wagenknecht LE, Kahn SE, Wing RR, Jablonski KA, Huggins GS, Knowler WC, Florez JC, McCaffery JM, Franks PW; Diabetes Prevention Program and the Look AHEAD Research Groups.

Diabetes. 2015 Dec;64(12):4312-21. doi: 10.2337/db15-0441. Epub 2015 Aug 7.


Using decision trees to understand structure in missing data.

Tierney NJ, Harden FA, Harden MJ, Mengersen KL.

BMJ Open. 2015 Jun 29;5(6):e007450. doi: 10.1136/bmjopen-2014-007450.


African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans.

Tandon A, Chen CJ, Penman A, Hancock H, James M, Husain D, Andreoli C, Li X, Kuo JZ, Idowu O, Riche D, Papavasilieou E, Brauner S, Smith SO, Hoadley S, Richardson C, Kieser T, Vazquez V, Chi C, Fernandez M, Harden M, Cotch MF, Siscovick D, Taylor HA, Wilson JG, Reich D, Wong TY, Klein R, Klein BE, Rotter JI, Patterson N, Sobrin L.

Invest Ophthalmol Vis Sci. 2015 Jun;56(6):3999-4005. doi: 10.1167/iovs.15-16674.


Macacine Herpesvirus 1 in Long-Tailed Macaques, Malaysia, 2009-2011.

Lee MH, Rostal MK, Hughes T, Sitam F, Lee CY, Japning J, Harden ME, Griffiths A, Basir M, Wolfe ND, Epstein JH, Daszak P.

Emerg Infect Dis. 2015 Jul;21(7):1107-13. doi: 10.3201/eid2107.140162.


Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation.

Van Allen EM, Golay HG, Liu Y, Koyama S, Wong K, Taylor-Weiner A, Giannakis M, Harden M, Rojas-Rudilla V, Chevalier A, Thai T, Lydon C, Mach S, Avila AG, Wong JA, Rabin AR, Helmkamp J, Sholl L, Carter SL, Oxnard G, Janne P, Getz G, Lindeman N, Hammerman PS, Garraway LA, Hodi FS, Rodig SJ, Dranoff G, Wong KK, Barbie DA.

Cancer Immunol Res. 2015 Aug;3(8):855-63. doi: 10.1158/2326-6066.CIR-15-0024. Epub 2015 May 26.


Psychiatric symptoms in patients with sporadic Creutzfeldt-Jakob disease in Germany.

Krasnianski A, Bohling GT, Harden M, Zerr I.

J Clin Psychiatry. 2015 Sep;76(9):1209-15. doi: 10.4088/JCP.13m08915.


Service user engagement and health service reconfiguration: a rapid evidence synthesis.

Dalton J, Chambers D, Harden M, Street A, Parker G, Eastwood A.

Southampton (UK): NIHR Journals Library; 2015 Apr.


The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.

Walford GA, Colomo N, Todd JN, Billings LK, Fernandez M, Chamarthi B, Warner AS, Davis J, Littleton KR, Hernandez AM, Fanelli RR, Lanier A, Barbato C, Ackerman RJ, Khan SQ, Bui R, Garber L, Stolerman ES, Moore AF, Huang C, Kaur V, Harden M, Taylor A, Chen L, Manning AK, Huang P, Wexler D, McCarthy RM, Lo J, Thomas MK, Grant RW, Goldfine A, Hudson MS, Florez JC.

PLoS One. 2015 Mar 26;10(3):e0121553. doi: 10.1371/journal.pone.0121553. eCollection 2015.


An exploration of the implementation of open disclosure of adverse events in the UK: a scoping review and qualitative exploration.

Birks Y, Harrison R, Bosanquet K, Hall J, Harden M, Entwistle V, Watt I, Walsh P, Ronaldson S, Roberts D, Adamson J, Wright J, Iedema R.

Southampton (UK): NIHR Journals Library; 2014 Jul.


Acid-adapted strains of Escherichia coli K-12 obtained by experimental evolution.

Harden MM, He A, Creamer K, Clark MW, Hamdallah I, Martinez KA 2nd, Kresslein RL, Bush SP, Slonczewski JL.

Appl Environ Microbiol. 2015 Mar;81(6):1932-41. doi: 10.1128/AEM.03494-14. Epub 2015 Jan 2.


Interventions for adult Eustachian tube dysfunction: a systematic review.

Llewellyn A, Norman G, Harden M, Coatesworth A, Kimberling D, Schilder A, McDaid C.

Health Technol Assess. 2014 Jul;18(46):1-180, v-vi. doi: 10.3310/hta18460. Review.


Behaviour change interventions to promote prescribing of generic drugs: a rapid evidence synthesis and systematic review.

Moe-Byrne T, Chambers D, Harden M, McDaid C.

BMJ Open. 2014 May 14;4(5):e004623. doi: 10.1136/bmjopen-2013-004623. Review.


Systematic review of the limited evidence base for treatments of Eustachian tube dysfunction: a health technology assessment.

Norman G, Llewellyn A, Harden M, Coatesworth A, Kimberling D, Schilder A, McDaid C.

Clin Otolaryngol. 2014 Feb;39(1):6-21. doi: 10.1111/coa.12220. Review.


Malignant Cardiac Tamponade from Non-Small Cell Lung Cancer: Case Series from the Era of Molecular Targeted Therapy.

Li BT, Pearson A, Pavlakis N, Bell D, Lee A, Chan D, Harden M, Mathur M, Marshman D, Brady P, Clarke S.

J Clin Med. 2014 Dec 30;4(1):75-84. doi: 10.3390/jcm4010075.


Acupuncture and other physical treatments for the relief of pain due to osteoarthritis of the knee: network meta-analysis.

Corbett MS, Rice SJ, Madurasinghe V, Slack R, Fayter DA, Harden M, Sutton AJ, Macpherson H, Woolacott NF.

Osteoarthritis Cartilage. 2013 Sep;21(9):1290-8. doi: 10.1016/j.joca.2013.05.007. Review.


The contribution of nurses to incident disclosure: a narrative review.

Harrison R, Birks Y, Hall J, Bosanquet K, Harden M, Iedema R.

Int J Nurs Stud. 2014 Feb;51(2):334-45. doi: 10.1016/j.ijnurstu.2013.07.001. Epub 2013 Jul 30. Review.


The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.

Ezzat S, Zheng L, Florez JC, Stefan N, Mayr T, Hliang MM, Jablonski K, Harden M, Stančáková A, Laakso M, Haring HU, Ullrich A, Asa SL.

Cell Metab. 2013 Jun 4;17(6):929-40. doi: 10.1016/j.cmet.2013.05.002.


Escherichia coli K-12 survives anaerobic exposure at pH 2 without RpoS, Gad, or hydrogenases, but shows sensitivity to autoclaved broth products.

Riggins DP, Narvaez MJ, Martinez KA, Harden MM, Slonczewski JL.

PLoS One. 2013;8(3):e56796. doi: 10.1371/journal.pone.0056796. Epub 2013 Mar 8.


Lower versus higher oxygen concentration for delivery room stabilisation of preterm neonates: systematic review.

Brown JV, Moe-Byrne T, Harden M, McGuire W.

PLoS One. 2012;7(12):e52033. doi: 10.1371/journal.pone.0052033. Epub 2012 Dec 20. Review.

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