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Items: 40

1.

A standardized approach to the evaluation of antivirals against DNA viruses: Orthopox-, adeno-, and herpesviruses.

Hartline CB, Keith KA, Eagar J, Harden EA, Bowlin TL, Prichard MN.

Antiviral Res. 2018 Nov;159:104-112. doi: 10.1016/j.antiviral.2018.09.015. Epub 2018 Oct 1.

PMID:
30287226
2.

Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification.

Beadle JR, Valiaeva N, Yang G, Yu JH, Broker TR, Aldern KA, Harden EA, Keith KA, Prichard MN, Hartman T, Buckheit RW Jr, Chow LT, Hostetler KY.

J Med Chem. 2016 Dec 8;59(23):10470-10478. Epub 2016 Nov 28.

PMID:
27933957
3.

SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer.

van Reesema LLS, Zheleva V, Winston JS, Jansen RJ, O'Connor CF, Isbell AJ, Bian M, Qin R, Bassett PT, Hinson VJ, Dorsch KA, Kirby BW, Van Sciver RE, Tang-Tan AM, Harden EA, Chang DZ, Allen CA, Perry RR, Hoefer RA, Tang AH.

EBioMedicine. 2016 Sep;11:183-198. doi: 10.1016/j.ebiom.2016.08.014. Epub 2016 Aug 14.

4.

Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.

Prichard MN, Williams JD, Komazin-Meredith G, Khan AR, Price NB, Jefferson GM, Harden EA, Hartline CB, Peet NP, Bowlin TL.

Antimicrob Agents Chemother. 2013 Aug;57(8):3518-27. doi: 10.1128/AAC.00429-13. Epub 2013 May 13.

5.

Mixed treatment comparison of the treatment discontinuations of biologic disease-modifying antirheumatic drugs in adults with rheumatoid arthritis.

Desai RJ, Hansen RA, Rao JK, Wilkins TM, Harden EA, Yuen A, Jonas DE, Roubey R, Jonas B, Gartlehner G, Lux L, Donahue KE.

Ann Pharmacother. 2012 Nov;46(11):1491-505. doi: 10.1345/aph.1R203. Epub 2012 Oct 23. Review.

PMID:
23092868
6.

Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides.

Williams JD, Khan AR, Harden EA, Hartline CB, Jefferson GM, Keith KA, Prichard MN, Zemlicka J, Peet NP, Bowlin TL.

Bioorg Med Chem. 2012 Jun 15;20(12):3710-8. doi: 10.1016/j.bmc.2012.04.049. Epub 2012 May 1.

7.

Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase.

James SH, Hartline CB, Harden EA, Driebe EM, Schupp JM, Engelthaler DM, Keim PS, Bowlin TL, Kern ER, Prichard MN.

Antimicrob Agents Chemother. 2011 Oct;55(10):4682-91. doi: 10.1128/AAC.00571-11. Epub 2011 Jul 25.

8.

Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.

Prichard MN, Quenelle DC, Hartline CB, Harden EA, Jefferson G, Frederick SL, Daily SL, Whitley RJ, Tiwari KN, Maddry JA, Secrist JA 3rd, Kern ER.

Antimicrob Agents Chemother. 2009 Dec;53(12):5251-8. doi: 10.1128/AAC.00417-09. Epub 2009 Sep 21.

9.

Virucidal activity of polysaccharide extracts from four algal species against herpes simplex virus.

Harden EA, Falshaw R, Carnachan SM, Kern ER, Prichard MN.

Antiviral Res. 2009 Sep;83(3):282-9. doi: 10.1016/j.antiviral.2009.06.007. Epub 2009 Jul 1.

10.

Transcriptional regulation of subclass 5b fimbriae.

Bodero MD, Harden EA, Munson GP.

BMC Microbiol. 2008 Oct 14;8:180. doi: 10.1186/1471-2180-8-180.

11.

Inhibition of herpesvirus replication by hexadecyloxypropyl esters of purine- and pyrimidine-based phosphonomethoxyethyl nucleoside phosphonates.

Prichard MN, Hartline CB, Harden EA, Daily SL, Beadle JR, Valiaeva N, Kern ER, Hostetler KY.

Antimicrob Agents Chemother. 2008 Dec;52(12):4326-30. doi: 10.1128/AAC.00918-08. Epub 2008 Oct 13.

12.

Selective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase.

Prichard MN, Keith KA, Johnson MP, Harden EA, McBrayer A, Luo M, Qiu S, Chattopadhyay D, Fan X, Torrence PF, Kern ER.

Antimicrob Agents Chemother. 2007 May;51(5):1795-803. Epub 2007 Feb 26.

13.

Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs.

Prichard MN, Williams AD, Keith KA, Harden EA, Kern ER.

Antiviral Res. 2006 Aug;71(1):1-6. Epub 2006 Feb 28.

PMID:
16530858
14.

Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro.

Williams-Aziz SL, Hartline CB, Harden EA, Daily SL, Prichard MN, Kushner NL, Beadle JR, Wan WB, Hostetler KY, Kern ER.

Antimicrob Agents Chemother. 2005 Sep;49(9):3724-33.

15.

In vitro activity and mechanism of action of methylenecyclopropane analogs of nucleosides against herpesvirus replication.

Kern ER, Kushner NL, Hartline CB, Williams-Aziz SL, Harden EA, Zhou S, Zemlicka J, Prichard MN.

Antimicrob Agents Chemother. 2005 Mar;49(3):1039-45.

16.

Inhibition of herpesvirus replication by a series of 4-oxo-dihydroquinolines with viral polymerase activity.

Hartline CB, Harden EA, Williams-Aziz SL, Kushner NL, Brideau RJ, Kern ER.

Antiviral Res. 2005 Feb;65(2):97-105.

PMID:
15708636
17.

Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro.

Kushner NL, Williams SL, Hartline CB, Harden EA, Bidanset DJ, Chen X, Zemlicka J, Kern ER.

Nucleosides Nucleotides Nucleic Acids. 2003 Dec;22(12):2105-19.

PMID:
14714760
18.

In vitro activities of benzimidazole D- and L-ribonucleosides against herpesviruses.

Williams SL, Hartline CB, Kushner NL, Harden EA, Bidanset DJ, Drach JC, Townsend LB, Underwood MR, Biron KK, Kern ER.

Antimicrob Agents Chemother. 2003 Jul;47(7):2186-92.

19.

Carmustine, Ara C, cyclophosphamide and etoposide with autologous bone marrow transplantation in relapsed or refractory lymphoma: a dose-finding study.

Snyder MJ, Johnson DB, Daly MB, Giguere JK, Harman GH, Harden EA, Johnson RA, Leff RS, Mercier RJ, Messerschmidt GL, et al.

Bone Marrow Transplant. 1994 Oct;14(4):595-600.

PMID:
7858534
20.

Reduced renal accumulation and toxicity of cisplatin in experimental galactosemia.

Cacini W, Harden EA, Skau KA.

Proc Soc Exp Biol Med. 1993 Jul;203(3):348-53.

PMID:
8516346
21.

Dose-related cutaneous toxicities with etoposide.

Murphy CP, Harden EA, Herzig RH.

Cancer. 1993 May 15;71(10):3153-5.

PMID:
8490845
22.

Encephalopathy and seizures induced by intravesical alum irrigations.

Murphy CP, Cox RL, Harden EA, Stevens DA, Heye MM, Herzig RH.

Bone Marrow Transplant. 1992 Oct;10(4):383-5.

PMID:
1422497
23.

Generalized seizures secondary to high-dose busulfan therapy.

Murphy CP, Harden EA, Thompson JM.

Ann Pharmacother. 1992 Jan;26(1):30-1.

PMID:
1606341
24.

Bone marrow purging in patients with refractory cancer.

Meagher RC, Stevens DA, Herzig GP, Fay JW, Harden EA, Montes VM, Heye MM, Herzig RH.

Prog Clin Biol Res. 1992;377:281-7. No abstract available.

PMID:
1438426
25.
26.

High-dose etoposide and cyclophosphamide without bone marrow transplantation for resistant hematologic malignancy.

Brown RA, Herzig RH, Wolff SN, Frei-Lahr D, Pineiro L, Bolwell BJ, Lowder JN, Harden EA, Hande KR, Herzig GP.

Blood. 1990 Aug 1;76(3):473-9.

27.

Hodgkin's lymphoma of the uterus presenting as refractory pelvic inflammatory disease. A case report.

Raggio ML, Bostrom SG, Harden EA.

J Reprod Med. 1988 Oct;33(10):827-30.

PMID:
3193414
28.
29.

Acute neurologic dysfunction after high-dose etoposide therapy for malignant glioma.

Leff RS, Thompson JM, Daly MB, Johnson DB, Harden EA, Mercier RJ, Messerschmidt GL.

Cancer. 1988 Jul 1;62(1):32-5.

PMID:
3289726
30.

The Pawtucket Heart Health Program. III. Social marketing to promote community health.

Lefebvre RC, Harden EA, Zompa B.

R I Med J. 1988 Jan;71(1):27-30. No abstract available.

PMID:
3422499
31.

Case report 487: Primary lymphoma of radius.

Genez BM, Zirilli VL, Schlesinger AE, Harden EA, Murphy KD, Dryer RF.

Skeletal Radiol. 1988;17(4):306-9. No abstract available.

PMID:
3062793
32.

Characteristics of participants in community health promotion programs: four-year results.

Lefebvre RC, Harden EA, Rakowski W, Lasater TM, Carleton RA.

Am J Public Health. 1987 Oct;77(10):1342-4.

33.
34.

Expression of antigens by cultured epithelial cells: comparison of epidermis and thymic epithelium.

Singer KH, Harden EA, Robertson AL, Lobach DF, Haynes BF.

J Invest Dermatol. 1985 Jul;85(1 Suppl):67s-71s.

35.

In vitro growth and phenotypic characterization of mesodermal-derived and epithelial components of normal and abnormal human thymus.

Singer KH, Harden EA, Robertson AL, Lobach DF, Haynes BF.

Hum Immunol. 1985 Jul;13(3):161-76.

PMID:
3874195
36.

Phenotypic and functional characterization of human malignant T cells.

Harden EA, Haynes BF.

Semin Hematol. 1985 Jan;22(1):13-26. Review.

PMID:
3918348
37.

Mitomycin-induced hemolytic-uremic syndrome.

Proia AD, Harden EA, Silberman HR.

Arch Pathol Lab Med. 1984 Dec;108(12):959-62.

PMID:
6210069
38.

Leukemia-associated arthritis: identification of leukemic cells in synovial fluid using monoclonal and polyclonal antibodies.

Harden EA, Moore JO, Haynes BF.

Arthritis Rheum. 1984 Nov;27(11):1306-8. No abstract available.

PMID:
6497923
39.

Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation.

Haynes BF, Harden EA, Telen MJ, Hemler ME, Strominger JL, Palker TJ, Scearce RM, Eisenbarth GS.

J Immunol. 1983 Sep;131(3):1195-200.

PMID:
6224850
40.

Effect of thymectomy on peripheral lymphocyte subsets in myasthenia gravis: selective effect on T-cells in patients with thymic atrophy.

Haynes BF, Harden EA, Olanow CW, Eisenbarth GS, Wechsler AS, Hensley LL, Roses AD.

J Immunol. 1983 Aug;131(2):773-7.

PMID:
6408188

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