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Items: 5


ATP promotes the fast migration of dendritic cells through the activity of pannexin 1 channels and P2X7 receptors.

Sáez PJ, Vargas P, Shoji KF, Harcha PA, Lennon-Duménil AM, Sáez JC.

Sci Signal. 2017 Nov 21;10(506). pii: eaah7107. doi: 10.1126/scisignal.aah7107.


Hemichannels Are Required for Amyloid β-Peptide-Induced Degranulation and Are Activated in Brain Mast Cells of APPswe/PS1dE9 Mice.

Harcha PA, Vargas A, Yi C, Koulakoff AA, Giaume C, Sáez JC.

J Neurosci. 2015 Jun 24;35(25):9526-38. doi: 10.1523/JNEUROSCI.3686-14.2015.


Pannexin1 channels act downstream of P2X 7 receptors in ATP-induced murine T-cell death.

Shoji KF, Sáez PJ, Harcha PA, Aguila HL, Sáez JC.

Channels (Austin). 2014;8(2):142-56. doi: 10.4161/chan.28122. Epub 2014 Mar 3.


Possible involvement of TLRs and hemichannels in stress-induced CNS dysfunction via mastocytes, and glia activation.

Aguirre A, Maturana CJ, Harcha PA, Sáez JC.

Mediators Inflamm. 2013;2013:893521. doi: 10.1155/2013/893521. Epub 2013 Jul 2. Review.


ATP is required and advances cytokine-induced gap junction formation in microglia in vitro.

Sáez PJ, Shoji KF, Retamal MA, Harcha PA, Ramírez G, Jiang JX, von Bernhardi R, Sáez JC.

Mediators Inflamm. 2013;2013:216402. doi: 10.1155/2013/216402. Epub 2013 Apr 23.

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