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Items: 32

1.

Single-cell Wnt signaling niches maintain stemness of alveolar type 2 cells.

Nabhan AN, Brownfield DG, Harbury PB, Krasnow MA, Desai TJ.

Science. 2018 Mar 9;359(6380):1118-1123. doi: 10.1126/science.aam6603. Epub 2018 Feb 1.

2.

Automated cell-type classification in intact tissues by single-cell molecular profiling.

Nagendran M, Riordan DP, Harbury PB, Desai TJ.

Elife. 2018 Jan 10;7. pii: e30510. doi: 10.7554/eLife.30510.

3.

Ultrasensitive optical imaging with lanthanide lumiphores.

Cho U, Riordan DP, Ciepla P, Kocherlakota KS, Chen JK, Harbury PB.

Nat Chem Biol. 2018 Jan;14(1):15-21. doi: 10.1038/nchembio.2513. Epub 2017 Nov 6.

4.

Determination of the conformational ensemble of the TAR RNA by X-ray scattering interferometry.

Shi X, Walker P, Harbury PB, Herschlag D.

Nucleic Acids Res. 2017 May 5;45(8):e64. doi: 10.1093/nar/gkw1352.

5.

Directed Chemical Evolution with an Outsized Genetic Code.

Krusemark CJ, Tilmans NP, Brown PO, Harbury PB.

PLoS One. 2016 Aug 10;11(8):e0154765. doi: 10.1371/journal.pone.0154765. eCollection 2016.

6.

The solution structural ensembles of RNA kink-turn motifs and their protein complexes.

Shi X, Huang L, Lilley DM, Harbury PB, Herschlag D.

Nat Chem Biol. 2016 Mar;12(3):146-52. doi: 10.1038/nchembio.1997. Epub 2016 Jan 4.

7.

From a structural average to the conformational ensemble of a DNA bulge.

Shi X, Beauchamp KA, Harbury PB, Herschlag D.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1473-80. doi: 10.1073/pnas.1317032111. Epub 2014 Mar 31.

8.

Mesofluidic devices for DNA-programmed combinatorial chemistry.

Weisinger RM, Marinelli RJ, Wrenn SJ, Harbury PB.

PLoS One. 2012;7(3):e32299. doi: 10.1371/journal.pone.0032299. Epub 2012 Mar 29.

9.

Highly parallel translation of DNA sequences into small molecules.

Weisinger RM, Wrenn SJ, Harbury PB.

PLoS One. 2012;7(3):e28056. doi: 10.1371/journal.pone.0028056. Epub 2012 Mar 29.

10.

Structural and kinetic mapping of side-chain exposure onto the protein energy landscape.

Bernstein R, Schmidt KL, Harbury PB, Marqusee S.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10532-7. doi: 10.1073/pnas.1103629108. Epub 2011 Jun 13.

11.

Design of protein-ligand binding based on the molecular-mechanics energy model.

Boas FE, Harbury PB.

J Mol Biol. 2008 Jul 4;380(2):415-24. doi: 10.1016/j.jmb.2008.04.001. Epub 2008 Apr 8.

12.

Misincorporation proton-alkyl exchange (MPAX): engineering cysteine probes into proteins.

Burguete AS, Harbury PB, Pfeffer SR.

Curr Protoc Protein Sci. 2005 Dec;Chapter 26:Unit26.1. doi: 10.1002/0471140864.ps2601s42.

PMID:
18429287
13.

Synthetic ligands discovered by in vitro selection.

Wrenn SJ, Weisinger RM, Halpin DR, Harbury PB.

J Am Chem Soc. 2007 Oct 31;129(43):13137-43. Epub 2007 Oct 6.

14.

Chemical evolution as a tool for molecular discovery.

Wrenn SJ, Harbury PB.

Annu Rev Biochem. 2007;76:331-49. Review.

PMID:
17506635
15.

Potential energy functions for protein design.

Boas FE, Harbury PB.

Curr Opin Struct Biol. 2007 Apr;17(2):199-204. Epub 2007 Mar 26. Review.

PMID:
17387014
16.

Accurate, conformation-dependent predictions of solvent effects on protein ionization constants.

Barth P, Alber T, Harbury PB.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):4898-903. Epub 2007 Mar 14.

17.

In vitro selection and prediction of TIP47 protein-interaction interfaces.

Burguete AS, Harbury PB, Pfeffer SR.

Nat Methods. 2004 Oct;1(1):55-60. Epub 2004 Sep 29.

PMID:
15782153
18.

Structural test of the parameterized-backbone method for protein design.

Plecs JJ, Harbury PB, Kim PS, Alber T.

J Mol Biol. 2004 Sep 3;342(1):289-97.

PMID:
15313624
19.

DNA display III. Solid-phase organic synthesis on unprotected DNA.

Halpin DR, Lee JA, Wrenn SJ, Harbury PB.

PLoS Biol. 2004 Jul;2(7):E175. Epub 2004 Jun 22.

20.
21.

DNA display I. Sequence-encoded routing of DNA populations.

Halpin DR, Harbury PB.

PLoS Biol. 2004 Jul;2(7):E173. Epub 2004 Jun 22.

22.

The equilibrium unfolding pathway of a (beta/alpha)8 barrel.

Silverman JA, Harbury PB.

J Mol Biol. 2002 Dec 13;324(5):1031-40.

PMID:
12470957
23.

Automated design of specificity in molecular recognition.

Havranek JJ, Harbury PB.

Nat Struct Biol. 2003 Jan;10(1):45-52.

PMID:
12459719
24.

Rapid mapping of protein structure, interactions, and ligand binding by misincorporation proton-alkyl exchange.

Silverman JA, Harbury PB.

J Biol Chem. 2002 Aug 23;277(34):30968-75. Epub 2002 May 25.

25.

Reverse engineering the (beta/alpha )8 barrel fold.

Silverman JA, Balakrishnan R, Harbury PB.

Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3092-7.

26.

Modular enzymes.

Khosla C, Harbury PB.

Nature. 2001 Jan 11;409(6817):247-52. Review.

PMID:
11196653
27.

Tanford-Kirkwood electrostatics for protein modeling.

Havranek JJ, Harbury PB.

Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11145-50.

28.

High-resolution protein design with backbone freedom.

Harbury PB, Plecs JJ, Tidor B, Alber T, Kim PS.

Science. 1998 Nov 20;282(5393):1462-7.

29.

Repacking protein cores with backbone freedom: structure prediction for coiled coils.

Harbury PB, Tidor B, Kim PS.

Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8408-12.

30.

Crystal structure of an isoleucine-zipper trimer.

Harbury PB, Kim PS, Alber T.

Nature. 1994 Sep 1;371(6492):80-3.

PMID:
8072533
31.

A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants.

Harbury PB, Zhang T, Kim PS, Alber T.

Science. 1993 Nov 26;262(5138):1401-7.

PMID:
8248779
32.

Extraction of protein-bound ATP and ADP from human platelets in plasma.

Beurling-Harbury C, Harbury PB.

Thromb Haemost. 1990 Apr 12;63(2):286-90.

PMID:
2163554

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