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Microbiologic Changes Induced by Biliary Drainage Require Adapted Antibiotic Prophylaxis during Duodenopancreatectomy.

Windisch O, Frossard JL, Schiffer E, Harbarth S, Morel P, Bühler L.

Surg Infect (Larchmt). 2019 Jul 12. doi: 10.1089/sur.2019.088. [Epub ahead of print]


Performance of surgical site infection risk prediction models in colorectal surgery: external validity assessment from three European national surveillance networks.

Grant R, Aupee M, Buchs NC, Cooper K, Eisenring MC, Lamagni T, Ris F, Tanguy J, Troillet N, Harbarth S, Abbas M.

Infect Control Hosp Epidemiol. 2019 Jun 20:1-8. doi: 10.1017/ice.2019.163. [Epub ahead of print]


How to improve antibiotic awareness campaigns: findings of a WHO global survey.

Huttner B, Saam M, Moja L, Mah K, Sprenger M, Harbarth S, Magrini N.

BMJ Glob Health. 2019 May 9;4(3):e001239. doi: 10.1136/bmjgh-2018-001239. eCollection 2019.


Broadening the infection prevention and control network globally; 2017 Geneva IPC-think tank (part 3).

Zingg W, Storr J, Park BJ, Jernigan JA, Harbarth S, Grayson ML, Tacconelli E, Allegranzi B, Cardo D, Pittet D; 2017 Geneva-IPC Think Tank.

Antimicrob Resist Infect Control. 2019 May 10;8:74. doi: 10.1186/s13756-019-0528-0. eCollection 2019.


Estimands to quantify prolonged hospital stay associated with nosocomial infections.

Wolkewitz M, Schumacher M, Rücker G, Harbarth S, Beyersmann J.

BMC Med Res Methodol. 2019 May 31;19(1):111. doi: 10.1186/s12874-019-0752-6.


Effect of carbapenem resistance on outcomes of bloodstream infection caused by Enterobacteriaceae in low-income and middle-income countries (PANORAMA): a multinational prospective cohort study.

Stewardson AJ, Marimuthu K, Sengupta S, Allignol A, El-Bouseary M, Carvalho MJ, Hassan B, Delgado-Ramirez MA, Arora A, Bagga R, Owusu-Ofori AK, Ovosi JO, Aliyu S, Saad H, Kanj SS, Khanal B, Bhattarai B, Saha SK, Uddin J, Barman P, Sharma L, El-Banna T, Zahra R, Saleemi MA, Kaur A, Iregbu K, Uwaezuoke NS, Abi Hanna P, Feghali R, Correa AL, Munera MI, Le TAT, Tran TTN, Phukan C, Phukan C, Valderrama-Beltrán SL, Alvarez-Moreno C, Walsh TR, Harbarth S.

Lancet Infect Dis. 2019 Jun;19(6):601-610. doi: 10.1016/S1473-3099(18)30792-8. Epub 2019 Apr 29.


The pharmacokinetics of nitrofurantoin in healthy female volunteers: a randomized crossover study.

Huttner A, Wijma RA, Stewardson AJ, Olearo F, Von Dach E, Harbarth S, Brüggemann RJM, Mouton JW, Muller AE.

J Antimicrob Chemother. 2019 Jun 1;74(6):1656-1661. doi: 10.1093/jac/dkz095.


Nation-wide survey of screening practices to detect carriers of multi-drug resistant organisms upon admission to Swiss healthcare institutions.

Martischang R, Buetti N, Balmelli C, Saam M, Widmer A, Harbarth S.

Antimicrob Resist Infect Control. 2019 Feb 13;8:37. doi: 10.1186/s13756-019-0479-5. eCollection 2019.


Implementation of infection prevention and control in acute care hospitals in Mainland China - a systematic review.

Wang J, Liu F, Tan JBX, Harbarth S, Pittet D, Zingg W.

Antimicrob Resist Infect Control. 2019 Feb 11;8:32. doi: 10.1186/s13756-019-0481-y. eCollection 2019.


'A five-day course of oral antibiotics followed by faecal transplantation to eradicate carriage of multidrug-resistant Enterobacteriaceae' - Author's reply.

Huttner BD, Galperine T, Kapel N, Harbarth S.

Clin Microbiol Infect. 2019 Jul;25(7):914-915. doi: 10.1016/j.cmi.2019.02.001. Epub 2019 Feb 13. No abstract available.


Potential in vivo transfer of a blaCTX-M14-harbouring plasmid established by combining long- and short-read sequencing.

Xavier BB, Renzi G, Lammens C, Cherkaoui A, Goossens H, Schrenzel J, Harbarth S, Malhotra-Kumar S.

J Microbiol Methods. 2019 Apr;159:1-4. doi: 10.1016/j.mimet.2019.02.004. Epub 2019 Feb 7.


The successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex 'mix-and-match' implementation package.

Hays JP, Mitsakakis K, Luz S, van Belkum A, Becker K, van den Bruel A, Harbarth S, Rex JH, Simonsen GS, Werner G, Di Gregori V, Lüdke G, van Staa T, Moran-Gilad J, Bachmann TT; JPIAMR AMR-RDT consortium.

Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1015-1022. doi: 10.1007/s10096-019-03492-4. Epub 2019 Feb 2. Review.


A 5-day course of oral antibiotics followed by faecal transplantation to eradicate carriage of multidrug-resistant Enterobacteriaceae: a randomized clinical trial.

Huttner BD, de Lastours V, Wassenberg M, Maharshak N, Mauris A, Galperine T, Zanichelli V, Kapel N, Bellanger A, Olearo F, Duval X, Armand-Lefevre L, Carmeli Y, Bonten M, Fantin B, Harbarth S; R-Gnosis WP3 study group.

Clin Microbiol Infect. 2019 Jul;25(7):830-838. doi: 10.1016/j.cmi.2018.12.009. Epub 2019 Jan 4.


Combatting Antibiotic Resistance Together: How Can We Enlist the Help of Industry?

Edwards SE, Morel CM, Busse R, Harbarth S.

Antibiotics (Basel). 2018 Dec 18;7(4). pii: E111. doi: 10.3390/antibiotics7040111.


A community outbreak of Legionnaires' disease in Geneva, Switzerland, June to September 2017.

Zanella MC, Yerly S, Cherkaoui A, Renzi G, Mamin A, Lourenço Cordes L, Delaporte E, Baranczuk-Turska Z, Keiser O, Schrenzel J, Harbarth S, Gaia V, Kaiser L.

Swiss Med Wkly. 2018 Dec 2;148:w14687. doi: 10.4414/smw.2018.14687. eCollection 2018 Nov 19.


Impact of participation in a surgical site infection surveillance network: results from a large international cohort study.

Abbas M, de Kraker MEA, Aghayev E, Astagneau P, Aupee M, Behnke M, Bull A, Choi HJ, de Greeff SC, Elgohari S, Gastmeier P, Harrison W, Koek MBG, Lamagni T, Limon E, Løwer HL, Lyytikäinen O, Marimuthu K, Marquess J, McCann R, Prantner I, Presterl E, Pujol M, Reilly J, Roberts C, Segagni Lusignani L, Si D, Szilágyi E, Tanguy J, Tempone S, Troillet N, Worth LJ, Pittet D, Harbarth S.

J Hosp Infect. 2019 Jul;102(3):267-276. doi: 10.1016/j.jhin.2018.12.003. Epub 2018 Dec 7.


Control of Carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa in Healthcare Facilities: A Systematic Review and Reanalysis of Quasi-experimental Studies.

Tomczyk S, Zanichelli V, Grayson ML, Twyman A, Abbas M, Pires D, Allegranzi B, Harbarth S.

Clin Infect Dis. 2019 Feb 15;68(5):873-884. doi: 10.1093/cid/ciy752.


Should antibiotic prophylaxis before orthopedic implant surgery depend on the duration of pre-surgical hospital stay?

Davat M, Wuarin L, Stafylakis D, Abbas M, Harbarth S, Hannouche D, Uçkay I.

Antimicrob Resist Infect Control. 2018 Nov 8;7:131. doi: 10.1186/s13756-018-0421-2. eCollection 2018.


Adaptive designs in clinical trials in critically ill patients: principles, advantages and pitfalls.

van Werkhoven CH, Harbarth S, Bonten MJM.

Intensive Care Med. 2019 May;45(5):678-682. doi: 10.1007/s00134-018-5426-z. Epub 2018 Oct 30. No abstract available.


Impact of a multifaceted prevention program on ventilator-associated pneumonia including selective oropharyngeal decontamination.

Landelle C, Nocquet Boyer V, Abbas M, Genevois E, Abidi N, Naimo S, Raulais R, Bouchoud L, Boroli F, Terrisse H, Bosson JL, Harbarth S, Pugin J.

Intensive Care Med. 2018 Nov;44(11):1777-1786. doi: 10.1007/s00134-018-5227-4. Epub 2018 Oct 21.


Analysis of the clinical antibacterial and antituberculosis pipeline.

Theuretzbacher U, Gottwalt S, Beyer P, Butler M, Czaplewski L, Lienhardt C, Moja L, Paul M, Paulin S, Rex JH, Silver LL, Spigelman M, Thwaites GE, Paccaud JP, Harbarth S.

Lancet Infect Dis. 2019 Feb;19(2):e40-e50. doi: 10.1016/S1473-3099(18)30513-9. Epub 2018 Oct 15. Review.


Screening for Intestinal Carriage of Extended-spectrum Beta-lactamase-producing Enterobacteriaceae in Critically Ill Patients: Expected Benefits and Evidence-based Controversies.

Zahar JR, Blot S, Nordmann P, Martischang R, Timsit JF, Harbarth S, Barbier F.

Clin Infect Dis. 2019 May 30;68(12):2125-2130. doi: 10.1093/cid/ciy864.


Shining a light on ultraviolet-C disinfection: No golden promises for infection prevention.

de Kraker MEA, Harbarth S, Dancer SJ.

Am J Infect Control. 2018 Dec;46(12):1422-1423. doi: 10.1016/j.ajic.2018.07.026. Epub 2018 Oct 4. No abstract available.


Antibiotic Treatment for Uncomplicated Urinary Tract Infections-Reply.

Huttner A, Leibovici L, Harbarth S.

JAMA. 2018 Sep 25;320(12):1284-1285. doi: 10.1001/jama.2018.10018. No abstract available.


Ensuring Antibiotic Development, Equitable Availability, and Responsible Use of Effective Antibiotics: Recommendations for Multisectoral Action.

Monnier AA, Schouten J, Tebano G, Zanichelli V, Huttner BD, Pulcini C, Årdal C, Harbarth S, Hulscher ME, Gyssens IC.

Clin Infect Dis. 2019 May 17;68(11):1952-1959. doi: 10.1093/cid/ciy824.


Conflicts of interest in infection prevention and control research: no smoke without fire. A narrative review.

Abbas M, Pires D, Peters A, Morel CM, Hurst S, Holmes A, Saito H, Allegranzi B, Lucet JC, Zingg W, Harbarth S, Pittet D.

Intensive Care Med. 2018 Oct;44(10):1679-1690. doi: 10.1007/s00134-018-5361-z. Epub 2018 Sep 11. Review.


Carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae and the risk of surgical site infection after colorectal surgery: a prospective cohort study.

Dubinsky-Pertzov B, Temkin E, Harbarth S, Fankhauser-Rodriguez C, Carevic B, Radovanovic I, Ris F, Kariv Y, Buchs NC, Schiffer E, Cohen Percia S, Nutman A, Fallach N, Klausner J, Carmeli Y; R-GNOSIS WP4 study group.

Clin Infect Dis. 2018 Sep 10. doi: 10.1093/cid/ciy768. [Epub ahead of print]


Stimulating Research and Development of New Antibiotics While Ensuring Sustainable Use and Access: Further Insights from the DRIVE-AB Project and Others.

Bettiol E, Hackett J, Harbarth S.

J Law Med Ethics. 2018 Jun;46(1_suppl):5-8. doi: 10.1177/1073110518782910.


Emergence of ESBL-producing Escherichia coli ST131-C1-M27 clade colonizing patients in Europe.

Merino I, Hernández-García M, Turrientes MC, Pérez-Viso B, López-Fresneña N, Diaz-Agero C, Maechler F, Fankhauser-Rodriguez C, Kola A, Schrenzel J, Harbarth S, Bonten M, Gastmeier P, Canton R, Ruiz-Garbajosa P; R-GNOSIS Study Group .

J Antimicrob Chemother. 2018 Nov 1;73(11):2973-2980. doi: 10.1093/jac/dky296.


Optimizing the Design and Analysis of Clinical Trials for Antibacterials Against Multidrug-resistant Organisms: A White Paper From COMBACTE's STAT-Net.

de Kraker MEA, Sommer H, de Velde F, Gravestock I, Weiss E, McAleenan A, Nikolakopoulos S, Amit O, Ashton T, Beyersmann J, Held L, Lovering AM, MacGowan AP, Mouton JW, Timsit JF, Wilson D, Wolkewitz M, Bettiol E, Dane A, Harbarth S; COMBACTE-NET Consortium.

Clin Infect Dis. 2018 Nov 28;67(12):1922-1931. doi: 10.1093/cid/ciy516.


Remarkable geographical variations between India and Europe in carriage of the staphylococcal surface protein-encoding sasX/sesI and in the population structure of methicillin-resistant Staphylococcus aureus belonging to clonal complex 8.

De Backer S, Xavier BB, Vanjari L, Coppens J, Lammens C, Vemu L, Carevic B, Hryniewicz W, Jorens P, Kumar-Singh S, Lee A, Harbarth S, Schrenzel J, Tacconelli E, Goossens H, Malhotra-Kumar S.

Clin Microbiol Infect. 2019 May;25(5):628.e1-628.e7. doi: 10.1016/j.cmi.2018.07.024. Epub 2018 Aug 2.


Antibiotic resistance in Swiss nursing homes: analysis of National Surveillance Data over an 11-year period between 2007 and 2017.

Kohler P, Fulchini R, Albrich WC, Egli A, Balmelli C, Harbarth S, Héquet D, Kahlert CR, Kuster SP, Petignat C, Schlegel M, Kronenberg A.

Antimicrob Resist Infect Control. 2018 Jul 20;7:88. doi: 10.1186/s13756-018-0378-1. eCollection 2018.


Effectiveness of a hospital-wide infection control programme on the incidence of healthcare-associated infections and associated severe sepsis and septic shock: a prospective interventional study.

Hagel S, Ludewig K, Pletz MW, Frosinski J, Moeser A, Wolkewitz M, Gastmeier P, Harbarth S, Brunkhorst FM, Kesselmeier M, Scherag A.

Clin Microbiol Infect. 2019 Apr;25(4):462-468. doi: 10.1016/j.cmi.2018.07.010. Epub 2018 Jul 21.


Study protocol for a multicentre, cluster randomised, superiority trial evaluating the impact of computerised decision support, audit and feedback on antibiotic use: the COMPuterized Antibiotic Stewardship Study (COMPASS).

Catho G, De Kraker M, Waldispühl Suter B, Valotti R, Harbarth S, Kaiser L, Elzi L, Meyer R, Bernasconi E, Huttner BD.

BMJ Open. 2018 Jun 27;8(6):e022666. doi: 10.1136/bmjopen-2018-022666.


Infection prevention: is copper the new gold?

Abbas M, Pires D, Harbarth S, de Kraker MEA.

J Hosp Infect. 2019 Jan;101(1):109-110. doi: 10.1016/j.jhin.2018.06.012. Epub 2018 Jun 21. No abstract available.


Variation in antibiotic use among and within different settings: a systematic review.

Zanichelli V, Monnier AA, Gyssens IC, Adriaenssens N, Versporten A, Pulcini C, Le Maréchal M, Tebano G, Vlahovic-Palcevski V, Stanic Benic M, Milanic R, Harbarth S, Hulscher ME, Huttner B.

J Antimicrob Chemother. 2018 Jun 1;73(suppl_6):vi17-vi29. doi: 10.1093/jac/dky115.


Introduction: DRIVE-AB's definitions and indicators to monitor responsible antibiotic use.

Harbarth S, Hackett J.

J Antimicrob Chemother. 2018 Jun 1;73(suppl_6):vi2. doi: 10.1093/jac/dky113. No abstract available.


Methicillin-resistant Staphylococcus aureus.

Lee AS, de Lencastre H, Garau J, Kluytmans J, Malhotra-Kumar S, Peschel A, Harbarth S.

Nat Rev Dis Primers. 2018 May 31;4:18033. doi: 10.1038/nrdp.2018.33. Review.


Patient-related determinants of antibiotic use: a systematic review.

Zanichelli V, Tebano G, Gyssens IC, Vlahović-Palčevski V, Monnier AA, Stanic Benic M, Harbarth S, Hulscher M, Pulcini C, Huttner BD.

Clin Microbiol Infect. 2019 Jan;25(1):48-53. doi: 10.1016/j.cmi.2018.04.031. Epub 2018 May 17.


Views and experiences with regard to antibiotic use of hospitalized patients in five European countries: a qualitative descriptive study.

Zanichelli V, Monnier AA, Tebano G, Stanić BM, Gyssens IC, Pulcini C, Vlahović-Palčevski V, Schindler M, Harbarth S, Hulscher M, Huttner BD.

Clin Microbiol Infect. 2019 Feb;25(2):249.e7-249.e12. doi: 10.1016/j.cmi.2018.04.030. Epub 2018 May 17.


Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial.

Huttner A, Kowalczyk A, Turjeman A, Babich T, Brossier C, Eliakim-Raz N, Kosiek K, Martinez de Tejada B, Roux X, Shiber S, Theuretzbacher U, von Dach E, Yahav D, Leibovici L, Godycki-Cwirko M, Mouton JW, Harbarth S.

JAMA. 2018 May 1;319(17):1781-1789. doi: 10.1001/jama.2018.3627.


First case of Candida auris in Switzerland: discussion about preventive strategies.

Riat A, Neofytos D, Coste A, Harbarth S, Bizzini A, Grandbastien B, Pugin J, Lamoth F.

Swiss Med Wkly. 2018 Apr 26;148:w14622. doi: 10.4414/smw.2018.14622. eCollection 2018. No abstract available.


[Multiresistant bacteria : practical aspects for doctors working in ambulatory practice].

Masson-Roy S, Harbarth S.

Rev Med Suisse. 2018 Apr 11;14(602):795-799. French.


The Prevalence of Healthcare-Associated Infections in Mainland China: A Systematic Review and Meta-analysis.

Wang J, Liu F, Tartari E, Huang J, Harbarth S, Pittet D, Zingg W.

Infect Control Hosp Epidemiol. 2018 Jun;39(6):701-709. doi: 10.1017/ice.2018.60. Epub 2018 Apr 15.


Developing core elements and checklist items for global hospital antimicrobial stewardship programmes: a consensus approach.

Pulcini C, Binda F, Lamkang AS, Trett A, Charani E, Goff DA, Harbarth S, Hinrichsen SL, Levy-Hara G, Mendelson M, Nathwani D, Gunturu R, Singh S, Srinivasan A, Thamlikitkul V, Thursky K, Vlieghe E, Wertheim H, Zeng M, Gandra S, Laxminarayan R.

Clin Microbiol Infect. 2019 Jan;25(1):20-25. doi: 10.1016/j.cmi.2018.03.033. Epub 2018 Apr 3.


Risk prediction for Staphylococcus aureus surgical site infection following cardiothoracic surgery; A secondary analysis of the V710-P003 trial.

Paling FP, Olsen K, Ohneberg K, Wolkewitz M, Fowler VG Jr, DiNubile MJ, Jafri HS, Sifakis F, Bonten MJM, Harbarth SJ, Kluytmans JAJW.

PLoS One. 2018 Mar 21;13(3):e0193445. doi: 10.1371/journal.pone.0193445. eCollection 2018.


The effects of antibiotic cycling and mixing on antibiotic resistance in intensive care units: a cluster-randomised crossover trial.

van Duijn PJ, Verbrugghe W, Jorens PG, Spöhr F, Schedler D, Deja M, Rothbart A, Annane D, Lawrence C, Nguyen Van JC, Misset B, Jereb M, Seme K, Šifrer F, Tomiç V, Estevez F, Carneiro J, Harbarth S, Eijkemans MJC, Bonten M; SATURN consortium.

Lancet Infect Dis. 2018 Apr;18(4):401-409. doi: 10.1016/S1473-3099(18)30056-2. Epub 2018 Jan 26.


Effect of outpatient antibiotics for urinary tract infections on antimicrobial resistance among commensal Enterobacteriaceae: a multinational prospective cohort study.

Stewardson AJ, Vervoort J, Adriaenssens N, Coenen S, Godycki-Cwirko M, Kowalczyk A, Huttner BD, Lammens C, Malhotra-Kumar S, Goossens H, Harbarth S; SATURN WP1 Study Group; SATURN WP3 Study Group.

Clin Microbiol Infect. 2018 Sep;24(9):972-979. doi: 10.1016/j.cmi.2017.12.026. Epub 2018 Jan 10.


Classifying antibiotics in the WHO Essential Medicines List for optimal use-be AWaRe.

Sharland M, Pulcini C, Harbarth S, Zeng M, Gandra S, Mathur S, Magrini N; 21st WHO Expert Committee on Selection and Use of Essential Medicines.

Lancet Infect Dis. 2018 Jan;18(1):18-20. doi: 10.1016/S1473-3099(17)30724-7. Epub 2017 Dec 20. No abstract available.


Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis.

Tacconelli E, Carrara E, Savoldi A, Harbarth S, Mendelson M, Monnet DL, Pulcini C, Kahlmeter G, Kluytmans J, Carmeli Y, Ouellette M, Outterson K, Patel J, Cavaleri M, Cox EM, Houchens CR, Grayson ML, Hansen P, Singh N, Theuretzbacher U, Magrini N; WHO Pathogens Priority List Working Group.

Lancet Infect Dis. 2018 Mar;18(3):318-327. doi: 10.1016/S1473-3099(17)30753-3. Epub 2017 Dec 21.


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